Page last updated: 2024-11-04

sulpiride and Neuroleptic Malignant Syndrome

sulpiride has been researched along with Neuroleptic Malignant Syndrome in 21 studies

Sulpiride: A dopamine D2-receptor antagonist. It has been used therapeutically as an antidepressant, antipsychotic, and as a digestive aid. (From Merck Index, 11th ed)
sulpiride : A member of the class of benzamides obtained from formal condensation between the carboxy group of 2-methoxy-5-sulfamoylbenzoic acid and the primary amino group of (1-ethylpyrrolidin-2-yl)methylamine.

Neuroleptic Malignant Syndrome: A potentially fatal syndrome associated primarily with the use of neuroleptic agents (see ANTIPSYCHOTIC AGENTS) which are in turn associated with dopaminergic receptor blockade (see RECEPTORS, DOPAMINE) in the BASAL GANGLIA and HYPOTHALAMUS, and sympathetic dysregulation. Clinical features include diffuse MUSCLE RIGIDITY; TREMOR; high FEVER; diaphoresis; labile blood pressure; cognitive dysfunction; and autonomic disturbances. Serum CPK level elevation and a leukocytosis may also be present. (From Adams et al., Principles of Neurology, 6th ed, p1199; Psychiatr Serv 1998 Sep;49(9):1163-72)

Research Excerpts

ExcerptRelevanceReference
" She developed these symptoms after having been administered parenteral levosulpiride to control vomiting due to secondary adrenal insufficiency."7.88Levosulpiride-induced neuroleptic malignant syndrome in rheumatoid arthritis. ( Biswas, A; Desai, D; Gupta, K; Kumar, R, 2018)
" She developed these symptoms after having been administered parenteral levosulpiride to control vomiting due to secondary adrenal insufficiency."3.88Levosulpiride-induced neuroleptic malignant syndrome in rheumatoid arthritis. ( Biswas, A; Desai, D; Gupta, K; Kumar, R, 2018)
" Following an evaluation by the psychiatrist, a diagnosis of catatonic schizophrenia was made and he was started on oral sulpiride and benhexol."3.79Neuroleptic malignant syndrome masked by cerebral malaria. ( Rajesh, KM; Sakthi, AN; Sinnathamby, V, 2013)
" The authors present a case of amisulpiride-induced catatonia, further evaluation suggested neuroleptic malignant syndrome (NMS) and showed the occurrence of temporal lobe epilepsy (TLE) and underlying brain pathology with marked frontoparietal atrophy and periventricular white matter hyperintensities."3.75Catatonia, neuroleptics and brain damage--a case report. ( Chandran, M; El-Shazly, M, 2009)
"An amisulpride-induced neuroleptic malignant syndrome was therefore diagnosed as the patho-physiological mechanism leading to death."1.39Lethal neuroleptic malignant syndrome due to amisulpride. ( Doberentz, E; Madea, B; Musshoff, F, 2013)
"We reported a case of neuroleptic malignant syndrome (NMS) associated with the syndrome of inappropriate secretion of antidiuretic hormone (SIADH)."1.29[Neuroleptic malignant syndrome associated with the syndrome of inappropriate secretion of antidiuretic hormone]. ( Takamoto, K; Tanabe, H; Yagi, K; Yamaguchi, K, 1995)
"A case of recurrent neuroleptic malignant syndrome (NMS) occurring in a 29-year-old man with mild mental handicap and a superadded psychotic disorder is described."1.28Recurrent neuroleptic malignant syndrome in a man with mild mental handicap. ( Bambrick, M; Wilson, D, 1992)

Research

Studies (21)

TimeframeStudies, this research(%)All Research%
pre-19902 (9.52)18.7374
1990's7 (33.33)18.2507
2000's5 (23.81)29.6817
2010's6 (28.57)24.3611
2020's1 (4.76)2.80

Authors

AuthorsStudies
Kaur, U1
Acharya, K1
Singh, A1
Gambhir, IS1
Chakrabarti, SS1
Barrimi, M1
El Ghazouani, F1
Zaimi, O1
Oneib, B1
Desai, D1
Gupta, K1
Kumar, R1
Biswas, A1
Musshoff, F1
Doberentz, E1
Madea, B1
Rajesh, KM1
Sinnathamby, V1
Sakthi, AN1
Nabih, FO1
Benali, A1
Adali, I1
Manoudi, F1
Asri, F1
Chandran, M1
El-Shazly, M1
Yasugi, S1
Garg, V1
Been, G1
Magoulas, P1
Atbasoglu, EC1
Ozguven, HD1
Can Saka, M1
Goker, C1
Harter, C1
Obier, C1
Druschky, KF1
Eikelmann, B1
Abay, E1
Kose, R1
Parada, MA1
de Parada, MP1
Rada, P1
Hernandez, L1
Yamaguchi, K1
Takamoto, K1
Yagi, K1
Tanabe, H1
Nisijima, K1
Oyafuso, K1
Shimada, T1
Hosino, H1
Ishiguro, T1
Bottlender, R1
Jäger, M1
Hofschuster, E1
Dobmeier, P1
Möller, HJ1
Bambrick, M1
Wilson, D1
Ottervanger, JP1
Gerbrandy-Colijn, A1
Stricker, BH1
Watts, D1
Peet, M1
Collier, J1
Kashihara, K1
Ishida, K1
Lühdorf, K1
Kruse, A1
Schulz, V1

Other Studies

21 other studies available for sulpiride and Neuroleptic Malignant Syndrome

ArticleYear
Levosulpiride associated neuroleptic malignant syndrome in an elderly patient: a tale of confusing brand names.
    Acta neurologica Belgica, 2022, Volume: 122, Issue:4

    Topics: Aged; Antipsychotic Agents; Humans; Neuroleptic Malignant Syndrome; Sulpiride

2022
[Neuroleptic malignant syndrome under amisulpride in a patient during a second acute psychotic episode].
    Presse medicale (Paris, France : 1983), 2018, Volume: 47, Issue:2

    Topics: Acute Disease; Adult; Amisulpride; Antipsychotic Agents; Female; Humans; Neuroleptic Malignant Syndr

2018
Levosulpiride-induced neuroleptic malignant syndrome in rheumatoid arthritis.
    BMJ case reports, 2018, Aug-11, Volume: 2018

    Topics: Adrenal Insufficiency; Antiemetics; Arthritis, Rheumatoid; Diagnosis, Differential; Female; Humans;

2018
Lethal neuroleptic malignant syndrome due to amisulpride.
    Forensic science, medicine, and pathology, 2013, Volume: 9, Issue:2

    Topics: Adult; Amisulpride; Antipsychotic Agents; Autopsy; Cause of Death; Fatal Outcome; Forensic Pathology

2013
Neuroleptic malignant syndrome masked by cerebral malaria.
    BMJ case reports, 2013, May-22, Volume: 2013

    Topics: Adult; Antipsychotic Agents; Delayed Diagnosis; Fatal Outcome; Humans; Malaria, Cerebral; Malaria, F

2013
[Association of atypical neuroleptics with anticonvulsants and malignant syndrome. Report of 2 cases].
    The Pan African medical journal, 2014, Volume: 18

    Topics: Adolescent; Adult; Amisulpride; Anticonvulsants; Antipsychotic Agents; Benzodiazepines; Carbamazepin

2014
Catatonia, neuroleptics and brain damage--a case report.
    Journal of psychopharmacology (Oxford, England), 2009, Volume: 23, Issue:2

    Topics: Amisulpride; Antipsychotic Agents; Atrophy; Catatonia; Epilepsy, Temporal Lobe; Female; Frontal Lobe

2009
Neuroleptic malignant syndrome.
    The Australian and New Zealand journal of psychiatry, 2010, Volume: 44, Issue:6

    Topics: Adult; Amisulpride; Antimanic Agents; Antipsychotic Agents; Bipolar Disorder; Dose-Response Relation

2010
Rhabdomyolysis and coma associated with amisulpride: a probable atypical presentation of neuroleptic malignant syndrome.
    The Journal of clinical psychiatry, 2004, Volume: 65, Issue:12

    Topics: Adult; Amisulpride; Antipsychotic Agents; Coma; Creatine Kinase; Female; Humans; Leukocytosis; Neuro

2004
[Malignant neuroleptic syndrome associated with amisulpride].
    Der Nervenarzt, 2008, Volume: 79, Issue:1

    Topics: Affective Disorders, Psychotic; Amisulpride; Anticonvulsants; Antipsychotic Agents; Creatine Kinase;

2008
Amisulpride-induced neuroleptic malignant syndrome.
    The Journal of neuropsychiatry and clinical neurosciences, 2007,Fall, Volume: 19, Issue:4

    Topics: Aged; Amisulpride; Antipsychotic Agents; Bipolar Disorder; Creatine Kinase; Humans; Male; Neurolepti

2007
Sulpiride increases and dopamine decreases intracranial temperature in rats when injected in the lateral hypothalamus: an animal model for the neuroleptic malignant syndrome?
    Brain research, 1995, Mar-13, Volume: 674, Issue:1

    Topics: Animals; Body Temperature; Brain; Disease Models, Animal; Dopamine; Fever; Hypothalamic Area, Latera

1995
[Neuroleptic malignant syndrome associated with the syndrome of inappropriate secretion of antidiuretic hormone].
    Rinsho shinkeigaku = Clinical neurology, 1995, Volume: 35, Issue:2

    Topics: Aged; Female; Humans; Inappropriate ADH Syndrome; Neuroleptic Malignant Syndrome; Sulpiride

1995
Cerebrospinal fluid monoamine metabolism in a case of neuroleptic malignant syndrome improved by electroconvulsive therapy.
    Biological psychiatry, 1996, Mar-01, Volume: 39, Issue:5

    Topics: Antidepressive Agents; Antipsychotic Agents; Depressive Disorder; Electroconvulsive Therapy; Female;

1996
Neuroleptic malignant syndrome due to atypical neuroleptics: three episodes in one patient.
    Pharmacopsychiatry, 2002, Volume: 35, Issue:3

    Topics: Amisulpride; Antipsychotic Agents; Clozapine; Female; Humans; Middle Aged; Neuroleptic Malignant Syn

2002
Recurrent neuroleptic malignant syndrome in a man with mild mental handicap.
    Journal of intellectual disability research : JIDR, 1992, Volume: 36 ( Pt 4)

    Topics: Adult; Antipsychotic Agents; Carbamazepine; Dose-Response Relationship, Drug; Drug Therapy, Combinat

1992
[Fever caused by neuroleptics].
    Nederlands tijdschrift voor geneeskunde, 1992, Nov-14, Volume: 136, Issue:46

    Topics: Adult; Delayed-Action Preparations; Female; Fever; Haloperidol; Humans; Male; Middle Aged; Neurolept

1992
Neuroleptic malignant syndrome in a case of acute post-traumatic psychosis.
    The British journal of psychiatry : the journal of mental science, 1991, Volume: 159

    Topics: Antipsychotic Agents; Carbamazepine; Diagnosis, Differential; Haloperidol; Humans; Middle Aged; Neur

1991
Use of carbamazepine in psychosis after neuroleptic malignant syndrome.
    The British journal of psychiatry : the journal of mental science, 1990, Volume: 156

    Topics: Carbamazepine; Female; Humans; Neuroleptic Malignant Syndrome; Psychoses, Substance-Induced; Sulpiri

1990
Neuroleptic malignant syndrome due to sulpiride.
    Journal of neurology, neurosurgery, and psychiatry, 1988, Volume: 51, Issue:8

    Topics: Aged; Depressive Disorder; Female; Humans; Neuroleptic Malignant Syndrome; Sulpiride

1988
Neuroleptic malignant syndrome due to combination of penfluridol and sulpiride?
    Acta psychiatrica Scandinavica, 1987, Volume: 75, Issue:3

    Topics: Aged; Drug Interactions; Female; Humans; Middle Aged; Neuroleptic Malignant Syndrome; Penfluridol; P

1987