sulpiride has been researched along with Nerve Degeneration in 6 studies
Sulpiride: A dopamine D2-receptor antagonist. It has been used therapeutically as an antidepressant, antipsychotic, and as a digestive aid. (From Merck Index, 11th ed)
sulpiride : A member of the class of benzamides obtained from formal condensation between the carboxy group of 2-methoxy-5-sulfamoylbenzoic acid and the primary amino group of (1-ethylpyrrolidin-2-yl)methylamine.
Nerve Degeneration: Loss of functional activity and trophic degeneration of nerve axons and their terminal arborizations following the destruction of their cells of origin or interruption of their continuity with these cells. The pathology is characteristic of neurodegenerative diseases. Often the process of nerve degeneration is studied in research on neuroanatomical localization and correlation of the neurophysiology of neural pathways.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Bromocriptine was found to protect dopaminergic neurons from levodopa toxicity." | 1.30 | Bromocriptine protects dopaminergic neurons from levodopa-induced toxicity by stimulating D(2)receptors. ( Freed, WJ; Kishikawa, M; Takashima, H; Tsujihata, M, 1999) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (16.67) | 18.7374 |
| 1990's | 3 (50.00) | 18.2507 |
| 2000's | 2 (33.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Fuxe, K | 1 |
| Ogren, SO | 1 |
| Hall, H | 1 |
| Agnati, LF | 1 |
| Andersson, K | 1 |
| Köhler, C | 1 |
| Schwarcz, R | 1 |
| Wahl, F | 1 |
| Plotkine, M | 1 |
| Boulu, R | 1 |
| Obrenovitch, T | 1 |
| Symon, L | 1 |
| Takashima, H | 1 |
| Tsujihata, M | 1 |
| Kishikawa, M | 1 |
| Freed, WJ | 1 |
| Galvan, A | 1 |
| Floran, B | 2 |
| Erlij, D | 1 |
| Aceves, J | 2 |
| Marchese, G | 1 |
| Casu, MA | 1 |
| Bartholini, F | 1 |
| Ruiu, S | 1 |
| Saba, P | 1 |
| Gessa, GL | 1 |
| Pani, L | 1 |
| Martinez-Fong, D | 1 |
| Sierra, A | 1 |
| Hernandez, S | 1 |
| Mariscal, S | 1 |
6 other studies available for sulpiride and Nerve Degeneration
| Article | Year |
|---|---|
Effects of chronic treatment with l-sulpiride and haloperidol on central monoaminergic mechanisms.
Topics: 5-Hydroxytryptophan; Animals; Apomorphine; Behavior, Animal; Biogenic Amines; Brain; Haloperidol; Hy | 1980 |
Involvement of dopaminergic receptors in quinolinate-induced striatal lesions.
Topics: Animals; Corpus Striatum; Dopamine Agents; Dopamine Antagonists; Ergolines; Male; Necrosis; Nerve De | 1993 |
Bromocriptine protects dopaminergic neurons from levodopa-induced toxicity by stimulating D(2)receptors.
Topics: 1-Methyl-4-phenylpyridinium; Animals; Antiparkinson Agents; Antisense Elements (Genetics); Autorecep | 1999 |
Intrapallidal dopamine restores motor deficits induced by 6-hydroxydopamine in the rat.
Topics: Animals; Apomorphine; Benzazepines; Dopamine; Dopamine Agonists; Dopamine Antagonists; gamma-Aminobu | 2001 |
Sub-chronic treatment with classical but not atypical antipsychotics produces morphological changes in rat nigro-striatal dopaminergic neurons directly related to "early onset" vacuous chewing.
Topics: Amisulpride; Animals; Antipsychotic Agents; Clozapine; Dopamine; Dose-Response Relationship, Drug; D | 2002 |
L-dopa stimulates the release of [3H]gamma-aminobutyric acid in the basal ganglia of 6-hydroxydopamine lesioned rats.
Topics: Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Basal Ganglia; Benzazepines; Brain Chemistry; | 1991 |