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sulpiride and Neoplasms

sulpiride has been researched along with Neoplasms in 11 studies

Sulpiride: A dopamine D2-receptor antagonist. It has been used therapeutically as an antidepressant, antipsychotic, and as a digestive aid. (From Merck Index, 11th ed)
sulpiride : A member of the class of benzamides obtained from formal condensation between the carboxy group of 2-methoxy-5-sulfamoylbenzoic acid and the primary amino group of (1-ethylpyrrolidin-2-yl)methylamine.

Neoplasms: New abnormal growth of tissue. Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms.

Research Excerpts

ExcerptRelevanceReference
" We designed a comparative controlled study of Sulpiride and Domperidone, against nausea and vomiting during cancer chemotherapy."7.67[Clinical evaluation of sulpiride against nausea and vomiting during cancer chemotherapy compared with domperidone--envelope method]. ( Kawakami, K; Kawatsu, S; Komatsu, Y; Okamoto, K; Sakata, Y; Satoh, T; Suzuki, H; Takagi, S; Tanabe, K; Yoshida, Y, 1986)
"[125I] Iodosulpride binding was examined on eight human cell lines derived from lung, breast and digestive tract carcinomas, neuroblastomas and leukemia."3.67Presence of dopamine D-2 receptors in human tumoral cell lines. ( Martres, MP; Riou, JF; Schwartz, JC; Sokoloff, P, 1989)
" We designed a comparative controlled study of Sulpiride and Domperidone, against nausea and vomiting during cancer chemotherapy."3.67[Clinical evaluation of sulpiride against nausea and vomiting during cancer chemotherapy compared with domperidone--envelope method]. ( Kawakami, K; Kawatsu, S; Komatsu, Y; Okamoto, K; Sakata, Y; Satoh, T; Suzuki, H; Takagi, S; Tanabe, K; Yoshida, Y, 1986)
"Thirty patients with advanced cancer, who were no longer receiving antineoplastic therapy, were randomly assigned to receive either L 75 mg/day or M 30 mg/day."2.68Effectiveness of levosulpiride versus metoclopramide for nausea and vomiting in advanced cancer patients: a double-blind, randomized, crossover study. ( Battaiotto, L; Corli, O; Cozzolino, A, 1995)
"Family caregivers of cancer patients suffer from physical, psychological, and social distress and therefore are often referred to as second order patients."1.37Drug-induced akathisia as a cause of distress in spouse caregivers of cancer patients. ( Ishida, M; Ito, H; Iwamitsu, Y; Mizuno, K; Narabayashi, M; Onishi, H; Shioi, A; Tada, Y; Wada, M; Wada, T, 2011)
"One hundred six consecutive cancer outpatients with depressive symptoms were treated in a prospective, intention to treat, 4-week study, and were evaluated in single-blind with Montgomery Asberg rating scale for depression (MADRS), clinical global impression (CGI) and dosage record treatment emergent symptom scale (DOTES) to assess side effects of treatment."1.34Amisulpride in the short-term treatment of depressive and physical symptoms in cancer patients during chemotherapies. ( Berra, C; Binaschi, L; Borio, R; Torta, R, 2007)
"The third chapter develops non-hormonal treatments of menopause, their specific mode of action and advantages, with a reference to veralipride."1.27[Cancer and menopause]. ( Olivier, JP, 1984)
"The treatment of cancer pain by psychotropic drugs is a method which has been employed for a long time [8] and in which the results obtained have appeared very interesting from the beginning: there is a high percentage of success, rapid action, absence of addiction, and although there are sometimes unpleasant side-effects, they are reversible when the treatment is stopped."1.26Pain infirmity and psychotropic drugs in oncology. ( Boudouresque, G; Bourhis, A; Fondarai, J; Pellet, W; Ponzio, J; Spitalier, JM, 1978)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19904 (36.36)18.7374
1990's1 (9.09)18.2507
2000's4 (36.36)29.6817
2010's2 (18.18)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
De Simone, G1
Vitale, RM1
Di Fiore, A1
Pedone, C1
Scozzafava, A2
Montero, JL1
Winum, JY1
Supuran, CT2
Santos, MA1
Marques, S1
Vullo, D1
Innocenti, A1
Diamandis, P1
Wildenhain, J1
Clarke, ID1
Sacher, AG1
Graham, J1
Bellows, DS1
Ling, EK1
Ward, RJ1
Jamieson, LG1
Tyers, M1
Dirks, PB1
Lin, R1
Elf, S1
Shan, C1
Kang, HB1
Ji, Q1
Zhou, L1
Hitosugi, T1
Zhang, L1
Zhang, S1
Seo, JH1
Xie, J1
Tucker, M1
Gu, TL1
Sudderth, J1
Jiang, L1
Mitsche, M1
DeBerardinis, RJ1
Wu, S1
Li, Y1
Mao, H1
Chen, PR1
Wang, D1
Chen, GZ1
Hurwitz, SJ1
Lonial, S1
Arellano, ML1
Khoury, HJ1
Khuri, FR1
Lee, BH1
Lei, Q1
Brat, DJ1
Ye, K1
Boggon, TJ1
He, C1
Kang, S1
Fan, J1
Chen, J1
Wada, M2
Ito, H1
Wada, T1
Tada, Y1
Ishida, M1
Mizuno, K1
Shioi, A1
Narabayashi, M1
Iwamitsu, Y1
Onishi, H1
Torta, R1
Berra, C1
Binaschi, L1
Borio, R1
Olivier, JP1
Corli, O1
Cozzolino, A1
Battaiotto, L1
Bourhis, A1
Boudouresque, G1
Pellet, W1
Fondarai, J1
Ponzio, J1
Spitalier, JM1
Sokoloff, P1
Riou, JF1
Martres, MP1
Schwartz, JC1
Sakata, Y1
Suzuki, H1
Satoh, T1
Kawatsu, S1
Tanabe, K1
Okamoto, K1
Takagi, S1
Komatsu, Y1
Kawakami, K1
Yoshida, Y1

Reviews

1 review available for sulpiride and Neoplasms

ArticleYear
6-Phosphogluconate dehydrogenase links oxidative PPP, lipogenesis and tumour growth by inhibiting LKB1-AMPK signalling.
    Nature cell biology, 2015, Volume: 17, Issue:11

    Topics: AMP-Activated Protein Kinase Kinases; AMP-Activated Protein Kinases; Humans; Lipogenesis; Neoplasms;

2015

Trials

1 trial available for sulpiride and Neoplasms

ArticleYear
Effectiveness of levosulpiride versus metoclopramide for nausea and vomiting in advanced cancer patients: a double-blind, randomized, crossover study.
    Journal of pain and symptom management, 1995, Volume: 10, Issue:7

    Topics: Aged; Antiemetics; Cross-Over Studies; Double-Blind Method; Female; Gastrointestinal Agents; Humans;

1995

Other Studies

9 other studies available for sulpiride and Neoplasms

ArticleYear
Carbonic anhydrase inhibitors: Hypoxia-activatable sulfonamides incorporating disulfide bonds that target the tumor-associated isoform IX.
    Journal of medicinal chemistry, 2006, Sep-07, Volume: 49, Issue:18

    Topics: Antigens, Neoplasm; Carbonic Anhydrase II; Carbonic Anhydrase Inhibitors; Carbonic Anhydrase IX; Car

2006
Carbonic anhydrase inhibitors: inhibition of cytosolic/tumor-associated isoforms I, II, and IX with iminodiacetic carboxylates/hydroxamates also incorporating benzenesulfonamide moieties.
    Bioorganic & medicinal chemistry letters, 2007, Mar-15, Volume: 17, Issue:6

    Topics: Carbonic Anhydrase Inhibitors; Cell Membrane; Cytosol; Humans; Hydroxamic Acids; Indicators and Reag

2007
Chemical genetics reveals a complex functional ground state of neural stem cells.
    Nature chemical biology, 2007, Volume: 3, Issue:5

    Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutic

2007
Drug-induced akathisia as a cause of distress in spouse caregivers of cancer patients.
    Palliative & supportive care, 2011, Volume: 9, Issue:2

    Topics: Aged; Akathisia, Drug-Induced; Antidepressive Agents; Antipsychotic Agents; Azepines; Caregivers; De

2011
Amisulpride in the short-term treatment of depressive and physical symptoms in cancer patients during chemotherapies.
    Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2007, Volume: 15, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Amisulpride; Antipsychotic Agents; Cohort Studies; Depression; Femal

2007
[Cancer and menopause].
    La semaine des hopitaux : organe fonde par l'Association d'enseignement medical des hopitaux de Paris, 1984, Mar-01, Volume: 60, Issue:10

    Topics: Estrogens; Female; Humans; Menopause; Neoplasms; Sulpiride

1984
Pain infirmity and psychotropic drugs in oncology.
    Pain, 1978, Volume: 5, Issue:3

    Topics: Activities of Daily Living; Amitriptyline; Dose-Response Relationship, Drug; Humans; Methotrimeprazi

1978
Presence of dopamine D-2 receptors in human tumoral cell lines.
    Biochemical and biophysical research communications, 1989, Jul-31, Volume: 162, Issue:2

    Topics: Apomorphine; Breast Neoplasms; Cell Membrane; Digestive System Neoplasms; Dopamine; Humans; Iodine R

1989
[Clinical evaluation of sulpiride against nausea and vomiting during cancer chemotherapy compared with domperidone--envelope method].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1986, Volume: 13, Issue:7

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Domperidone; Drug Evaluation; Female; H

1986