sulpiride has been researched along with Narcolepsy in 2 studies
Sulpiride: A dopamine D2-receptor antagonist. It has been used therapeutically as an antidepressant, antipsychotic, and as a digestive aid. (From Merck Index, 11th ed)
sulpiride : A member of the class of benzamides obtained from formal condensation between the carboxy group of 2-methoxy-5-sulfamoylbenzoic acid and the primary amino group of (1-ethylpyrrolidin-2-yl)methylamine.
Narcolepsy: A condition characterized by recurrent episodes of daytime somnolence and lapses in consciousness (microsomnias) that may be associated with automatic behaviors and AMNESIA. CATAPLEXY; SLEEP PARALYSIS, and hypnagogic HALLUCINATIONS frequently accompany narcolepsy. The pathophysiology of this disorder includes sleep-onset rapid eye movement (REM) sleep, which normally follows stage III or IV sleep. (From Neurology 1998 Feb;50(2 Suppl 1):S2-S7)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Narcolepsy is a sleep disorder characterized by abnormal manifestations of rapid-eye-movement (REM) sleep and excessive daytime sleepiness." | 1.28 | Dopamine D2 mechanisms in canine narcolepsy. ( Arrigoni, J; Dement, WC; Guilleminault, C; Mignot, E; Miller, JD; Nishino, S; Valtier, D, 1991) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Okura, M | 1 |
| Riehl, J | 1 |
| Mignot, E | 2 |
| Nishino, S | 2 |
| Arrigoni, J | 1 |
| Valtier, D | 1 |
| Miller, JD | 1 |
| Guilleminault, C | 1 |
| Dement, WC | 1 |
2 other studies available for sulpiride and Narcolepsy
| Article | Year |
|---|---|
Sulpiride, a D2/D3 blocker, reduces cataplexy but not REM sleep in canine narcolepsy.
Topics: Animals; Arousal; Cataplexy; Dogs; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Electroen | 2000 |
Dopamine D2 mechanisms in canine narcolepsy.
Topics: Animals; Catalepsy; Dogs; Dopamine Antagonists; Ergolines; Motor Activity; Narcolepsy; Quinpirole; R | 1991 |