sulpiride has been researched along with Long QT Syndrome in 13 studies
Sulpiride: A dopamine D2-receptor antagonist. It has been used therapeutically as an antidepressant, antipsychotic, and as a digestive aid. (From Merck Index, 11th ed)
sulpiride : A member of the class of benzamides obtained from formal condensation between the carboxy group of 2-methoxy-5-sulfamoylbenzoic acid and the primary amino group of (1-ethylpyrrolidin-2-yl)methylamine.
Long QT Syndrome: A condition that is characterized by episodes of fainting (SYNCOPE) and varying degree of ventricular arrhythmia as indicated by the prolonged QT interval. The inherited forms are caused by mutation of genes encoding cardiac ion channel proteins. The two major forms are ROMANO-WARD SYNDROME and JERVELL-LANGE NIELSEN SYNDROME.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Sulpiride-induced torsades de pointes is rare." | 5.35 | Long QT syndrome and torsades de pointes induced by acute sulpiride poisoning. ( Chang, JH; Fang, CC; Weng, TI, 2009) |
| "There was 1 case of torsade de pointes in a thioridazine overdose." | 1.42 | Prolonged QT Risk Assessment in Antipsychotic Overdose Using the QT Nomogram. ( Berling, I; Isbister, GK, 2015) |
| "Amisulpride is used for the treatment of schizophrenia and part of its safety profile is that is has no effect on the QT interval in therapeutic doses." | 1.36 | Amisulpride overdose: suggested management of prolonged QTc. ( Stevenson, RJ, 2010) |
| "Sulpiride-induced torsades de pointes is rare." | 1.35 | Long QT syndrome and torsades de pointes induced by acute sulpiride poisoning. ( Chang, JH; Fang, CC; Weng, TI, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 7 (53.85) | 29.6817 |
| 2010's | 6 (46.15) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Berling, I | 1 |
| Isbister, GK | 3 |
| Barceló, B | 1 |
| Yates, C | 1 |
| Castanyer, B | 1 |
| Puiguriguer, J | 1 |
| Chang, JH | 1 |
| Weng, TI | 1 |
| Fang, CC | 1 |
| Balit, CR | 1 |
| Macleod, D | 1 |
| Duffull, SB | 2 |
| Stevenson, RJ | 1 |
| Joy, JP | 1 |
| Coulter, CV | 1 |
| Teng, PR | 1 |
| Shen, TY | 1 |
| Lai, TJ | 1 |
| Sugiyama, A | 2 |
| Satoh, Y | 1 |
| Shiina, H | 1 |
| Takeda, S | 1 |
| Hashimoto, K | 1 |
| Su, KP | 1 |
| Shen, WW | 1 |
| Chuang, CL | 1 |
| Chen, KP | 1 |
| Chen, CC | 1 |
| Ward, DI | 1 |
| Huang, BH | 1 |
| Hsia, CP | 1 |
| Chen, CY | 1 |
| Züchner, H | 1 |
1 review available for sulpiride and Long QT Syndrome
| Article | Year |
|---|---|
[Effects of clinically available drugs on the repolarization process of the heart assessed by the in vivo canine models].
Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Antipsychotic Agents; Antitubercular Agents; Cat | 2003 |
1 trial available for sulpiride and Long QT Syndrome
| Article | Year |
|---|---|
A pilot cross-over design study on QTc interval prolongation associated with sulpiride and haloperidol.
Topics: Adolescent; Adult; Antipsychotic Agents; Cross-Over Studies; Female; Haloperidol; Heart Conduction S | 2003 |
11 other studies available for sulpiride and Long QT Syndrome
| Article | Year |
|---|---|
Prolonged QT Risk Assessment in Antipsychotic Overdose Using the QT Nomogram.
Topics: Adolescent; Adult; Aged; Amisulpride; Antipsychotic Agents; Drug Overdose; Electrocardiography; Fema | 2015 |
[Prolonged QT interval in two cases of amisulpride overdose].
Topics: Amisulpride; Antipsychotic Agents; Drug Overdose; Female; Follow-Up Studies; Humans; Long QT Syndrom | 2010 |
Long QT syndrome and torsades de pointes induced by acute sulpiride poisoning.
Topics: Dopamine Antagonists; Female; Humans; Lidocaine; Long QT Syndrome; Magnesium Sulfate; Sulpiride; Tor | 2009 |
Amisulpride overdose is frequently associated with QT prolongation and torsades de pointes.
Topics: Adult; Amisulpride; Antipsychotic Agents; Bradycardia; Cohort Studies; Drug Overdose; Electrocardiog | 2010 |
Amisulpride overdose: suggested management of prolonged QTc.
Topics: Adult; Amisulpride; Antipsychotic Agents; Calcium; Drug Overdose; Humans; Hypocalcemia; Infusions, I | 2010 |
Prediction of torsade de pointes from the QT interval: analysis of a case series of amisulpride overdoses.
Topics: Adolescent; Adult; Amisulpride; Antipsychotic Agents; Dose-Response Relationship, Drug; Drug Overdos | 2011 |
Sulpiride-associated torsade de pointes in a woman with bipolar disorder.
Topics: Antimanic Agents; Antipsychotic Agents; Bipolar Disorder; Drug Therapy, Combination; Electrocardiogr | 2012 |
Torsadegenic action of the antipsychotic drug sulpiride assessed using in vivo canine models.
Topics: Action Potentials; Aged; Aged, 80 and over; Animals; Antipsychotic Agents; Dogs; Dopamine Antagonist | 2002 |
Two cases of amisulpride overdose: a cause for prolonged QT syndrome.
Topics: Adult; Amisulpride; Antipsychotic Agents; Calcium Gluconate; Female; Humans; Hypocalcemia; Infusions | 2005 |
Sulpiride induced torsade de pointes.
Topics: Aged; Antipsychotic Agents; Bipolar Disorder; Coronary Angiography; Dose-Response Relationship, Drug | 2007 |
[QT prolongation and torsade de pointes--tachycardia in therapy with maprotiline].
Topics: Amisulpride; Antidepressive Agents, Second-Generation; Antipsychotic Agents; Brain Damage, Chronic; | 2002 |