sulpiride has been researched along with Hypothermia in 9 studies
Sulpiride: A dopamine D2-receptor antagonist. It has been used therapeutically as an antidepressant, antipsychotic, and as a digestive aid. (From Merck Index, 11th ed)
sulpiride : A member of the class of benzamides obtained from formal condensation between the carboxy group of 2-methoxy-5-sulfamoylbenzoic acid and the primary amino group of (1-ethylpyrrolidin-2-yl)methylamine.
Hypothermia: Lower than normal body temperature, especially in warm-blooded animals.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A single high dose of apomorphine (10 mg x kg(-1)) produced not only contextual sensitization to and conditioning of climbing behavior, but also context-independent tolerance to hypothermia." | 7.71 | Inhibitory effects of MK-801 on contextual sensitization to climbing behavior and on development of tolerance to hypothermia induced by a single high dose of apomorphine. ( Jang, CG; Kim, HS; Lee, MK; Lee, SC; Oh, KW; Oh, SK; Park, WK; Seong, YH; Yun, JS, 2001) |
| "A single high dose of apomorphine (10 mg x kg(-1)) produced not only contextual sensitization to and conditioning of climbing behavior, but also context-independent tolerance to hypothermia." | 3.71 | Inhibitory effects of MK-801 on contextual sensitization to climbing behavior and on development of tolerance to hypothermia induced by a single high dose of apomorphine. ( Jang, CG; Kim, HS; Lee, MK; Lee, SC; Oh, KW; Oh, SK; Park, WK; Seong, YH; Yun, JS, 2001) |
| "0 mg/kg, ip) hypothermia was reversed by the central and peripheral administration of the D2 antagonists S-(-)-sulpiride (3." | 3.68 | Dopamine D2-receptors mediate hypothermia in mice: ICV and IP effects of agonists and antagonists. ( Michel, AD; Nunes, JL; Sharif, NA; Whiting, RL, 1991) |
| "The nonselective dopamine (DA) receptor agonists R(-)apomorphine (APO) and R(-)-N-n-propylnorapomorphine (NPA) elicited dose- and time-dependent hypothermia in mice with ED50 values of 300 and 18 micrograms/kg, respectively." | 3.67 | Hypothermia in mice: D2 dopamine receptor mediation and absence of spare receptors. ( Hizami, R; Kreuter, L; Meller, E, 1989) |
| "The hypothermia induced by apomorphine, a mixed dopamine (DA) agonist in male Swiss-Webster mice, was not blocked by the selective D-1 antagonist SCH 23390 but was completely blocked by the selective D-2 antagonists haloperidol, sulpiride and YM-09151-2." | 3.67 | Influence of D-1 receptor system on the D-2 receptor-mediated hypothermic response in mice. ( Fitten, J; Gordon, LI; Kodama, CK; Menon, MK, 1988) |
| "A new benzamide, cis-N-(1-benzyl-2-methylpyrrolidin - 3 - yl) - 5 - chloro - 2 - methoxy - 4 - methylaminobenzamide (YM-09151-2) exhibited more potent and longer-lasting inhibitory effects on apomorphine-induced behaviours (stereotyped behaviour, emesis and hypothermia), and methamphetamine-induced stereotyped behaviour, conditioned avoidance response and open field behaviour, conditioned avoidance response and open field behaviour than either structurally similar benzamides (YM-0850 and sulpiride) or classical neuroleptics [chlorpromazine (CPZ) and haloperidol(HPD)]." | 3.66 | Neuroleptic properties of cis-N-(1-benzyl-2-methylpyrrolidin-3-yl)-5-chloro-2-methoxy-4-methylaminobenzamide (YM-09151-2) with selective antidopaminergic activity. ( Maeno, H; Nishikori, K; Noshiro, O; Usuda, S, 1981) |
| " This variation for fluphenazine may be explained by the fact that its pKa value is closer to that of piracetam, thus preventing better bioavailability of the neuroleptic, or its better affinity for DA-1 dopaminergic receptors." | 1.27 | Piracetam interactions with neuroleptics in psychopharmacological tests. ( Bourin, M; Larousse, C; Poisson, L, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (55.56) | 18.7374 |
| 1990's | 2 (22.22) | 18.2507 |
| 2000's | 2 (22.22) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Usuda, S | 1 |
| Nishikori, K | 1 |
| Noshiro, O | 1 |
| Maeno, H | 1 |
| Buvat, J | 1 |
| Buvat-Herbaut, M | 1 |
| Parada, MA | 1 |
| de Parada, MP | 1 |
| Rada, P | 1 |
| Hernandez, L | 1 |
| Cryan, JF | 1 |
| Harkin, A | 1 |
| Naughton, M | 1 |
| Kelly, JP | 1 |
| Leonard, BE | 1 |
| Yun, JS | 1 |
| Kim, HS | 1 |
| Lee, MK | 1 |
| Oh, KW | 1 |
| Jang, CG | 1 |
| Park, WK | 1 |
| Seong, YH | 1 |
| Lee, SC | 1 |
| Oh, SK | 1 |
| Nunes, JL | 1 |
| Sharif, NA | 1 |
| Michel, AD | 1 |
| Whiting, RL | 1 |
| Meller, E | 1 |
| Hizami, R | 1 |
| Kreuter, L | 1 |
| Bourin, M | 1 |
| Poisson, L | 1 |
| Larousse, C | 1 |
| Menon, MK | 1 |
| Gordon, LI | 1 |
| Kodama, CK | 1 |
| Fitten, J | 1 |
1 review available for sulpiride and Hypothermia
| Article | Year |
|---|---|
[New data on the physiology and treatment of vasomotor menopausal flushing].
Topics: Animals; Climacteric; Clonidine; Estrogens; Female; Haplorhini; Humans; Hypothalamic Hormones; Hypot | 1983 |
8 other studies available for sulpiride and Hypothermia
| Article | Year |
|---|---|
Neuroleptic properties of cis-N-(1-benzyl-2-methylpyrrolidin-3-yl)-5-chloro-2-methoxy-4-methylaminobenzamide (YM-09151-2) with selective antidopaminergic activity.
Topics: Animals; Antipsychotic Agents; Apomorphine; Benzamides; Chlorpropamide; Dogs; Drug Evaluation, Precl | 1981 |
Sulpiride increases and dopamine decreases intracranial temperature in rats when injected in the lateral hypothalamus: an animal model for the neuroleptic malignant syndrome?
Topics: Animals; Body Temperature; Brain; Disease Models, Animal; Dopamine; Fever; Hypothalamic Area, Latera | 1995 |
Characterization of D-fenfluramine-induced hypothermia: evidence for multiple sites of action.
Topics: Adrenergic alpha-Antagonists; Analysis of Variance; Animals; Benzofurans; Body Temperature; Cerebral | 2000 |
Inhibitory effects of MK-801 on contextual sensitization to climbing behavior and on development of tolerance to hypothermia induced by a single high dose of apomorphine.
Topics: Animals; Apomorphine; Benzazepines; Conditioning, Psychological; Depression, Chemical; Dizocilpine M | 2001 |
Dopamine D2-receptors mediate hypothermia in mice: ICV and IP effects of agonists and antagonists.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Benzazepines; Body Temperature | 1991 |
Hypothermia in mice: D2 dopamine receptor mediation and absence of spare receptors.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Adrenergic alpha-Antagonists; Animals; A | 1989 |
Piracetam interactions with neuroleptics in psychopharmacological tests.
Topics: Amphetamines; Animals; Antipsychotic Agents; Apomorphine; Behavior, Animal; Drug Interactions; Fluph | 1986 |
Influence of D-1 receptor system on the D-2 receptor-mediated hypothermic response in mice.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Anti-Anxiety Agents; Apomorphin | 1988 |