sulpiride has been researched along with Hyperprolactinemia in 67 studies
Sulpiride: A dopamine D2-receptor antagonist. It has been used therapeutically as an antidepressant, antipsychotic, and as a digestive aid. (From Merck Index, 11th ed)
sulpiride : A member of the class of benzamides obtained from formal condensation between the carboxy group of 2-methoxy-5-sulfamoylbenzoic acid and the primary amino group of (1-ethylpyrrolidin-2-yl)methylamine.
Hyperprolactinemia: Increased levels of PROLACTIN in the BLOOD, which may be associated with AMENORRHEA and GALACTORRHEA. Relatively common etiologies include PROLACTINOMA, medication effect, KIDNEY FAILURE, granulomatous diseases of the PITUITARY GLAND, and disorders which interfere with the hypothalamic inhibition of prolactin release. Ectopic (non-pituitary) production of prolactin may also occur. (From Joynt, Clinical Neurology, 1992, Ch36, pp77-8)
| Excerpt | Relevance | Reference |
|---|---|---|
| " Hyperprolactinaemia generated by the dopamine D2 receptor antagonist, levosulpiride, is associated with higher levels of vasoinhibin in the vitreous of patients with DR, implying a beneficial outcome due to vasoinhibin-mediated inhibition of retinal vascular alterations." | 8.12 | Sulpiride-induced hyperprolactinaemia increases retinal vasoinhibin and protects against diabetic retinopathy in rats. ( Adán-Castro, E; Bertsch, T; Clapp, C; Díaz-Lezama, N; Martínez de la Escalera, G; Núñez, FF; Núñez-Amaro, CD; Ramírez-Hernández, G; Robles-Osorio, ML; Ruíz-Herrera, X; Siqueiros-Márquez, L; Triebel, J, 2022) |
| " We conducted this 6-month, parallel-group study to prospectively investigate the effects of the dopamine agonist cabergoline on sexual dysfunction in clinically stable patients with schizophrenia (DSM-IV, AP 194) and hyperprolactinemia (PRL > 20 ng/ml for men and PRL > 25 ng/ml for women)." | 7.79 | Effects of cabergoline on hyperprolactinemia, psychopathology, and sexual functioning in schizophrenic patients. ( Arvanitakis, P; Dimopoulou, K; Kalkavoura, CS; Lykouras, L; Michopoulos, I; Theodoropoulou, P; Tzebelikos, E, 2013) |
| "We aimed to develop an anovulation model, using sulpiride-induced hyperprolactinemia in common marmosets." | 7.70 | New hyperprolactinemia and anovulation model in common marmoset (Callithrix jacchus) and effect of cabergoline. ( Inada, Y; Kojima, M; Komatsu, H; Miyata, H; Moro, M; Torii, R, 1999) |
| "We investigated the influence of chronic (27-65 days) sulpiride-induced hyperprolactinemia on the menstrual cycles of four normal women." | 7.67 | Effects of chronic sulpiride-induced hyperprolactinemia on menstrual cycles of normal women. ( Aso, T; Morikawa, K; Motohashi, T; Oseko, F, 1988) |
| "Hyperprolactinemia was experimentally produced in rats by administration of ovine prolactin (oPRL) and sulpiride, and tried to evaluate the effect of hyperprolactinemia on ovarian receptor for luteinizing hormone (LH) as well as that on serum gonadotropin and steroid hormone levels." | 7.67 | Modulation of ovarian LH receptor and serum hormone levels in rats with hyperprolactinemia induced by administration of ovine prolactin or sulpiride. ( Fukushima, M; Ota, H; Wakizaka, A, 1986) |
| "The effect of a potent agonistic analog of LHRH, D-Trp6-LHRH, on hyperprolactinemia induced by sulpiride was studied in normal men." | 7.67 | D-Trp6-luteinizing hormone-releasing hormone inhibits sulpiride-induced hyperprolactinemia in normal men. ( Cabranes, JA; Calle, JR; Charro, AL; Rubio, MA; Schally, AV; Torres-Aleman, I, 1987) |
| "005) by sulpiride-induced hyperprolactinaemia." | 7.67 | Inhibition of ovulation, steroidogenesis and collagenolytic activity in rabbits by sulpiride-induced hyperprolactinaemia. ( Kawamura, N; Lin, KC; Mori, T; Okamura, H, 1988) |
| "Hyperprolactinemia is an important but neglected adverse effect of antipsychotic medication." | 6.73 | Time course of the changes in antipsychotic-induced hyperprolactinemia following the switch to aripiprazole. ( Chen, CH; Lu, ML; Shen, WW, 2008) |
| " First, in preclinical experiments in female rats the estradiol antagonist/agonist drug tamoxifen or estradiol itself have been shown to completely prevent the obesity provoked by the AP sulpiride, and to induce an endocrine-metabolic milieu that seems to counteract AP-induced obesity." | 4.80 | Body weight gain induced by antipsychotic drugs: mechanisms and management. ( Baptista, T, 1999) |
| " Hyperprolactinaemia generated by the dopamine D2 receptor antagonist, levosulpiride, is associated with higher levels of vasoinhibin in the vitreous of patients with DR, implying a beneficial outcome due to vasoinhibin-mediated inhibition of retinal vascular alterations." | 4.12 | Sulpiride-induced hyperprolactinaemia increases retinal vasoinhibin and protects against diabetic retinopathy in rats. ( Adán-Castro, E; Bertsch, T; Clapp, C; Díaz-Lezama, N; Martínez de la Escalera, G; Núñez, FF; Núñez-Amaro, CD; Ramírez-Hernández, G; Robles-Osorio, ML; Ruíz-Herrera, X; Siqueiros-Márquez, L; Triebel, J, 2022) |
| "Levosulpiride/Cimetidine treatment induced mild hyperprolactinaemia that was associated with NKC activation and Th1-type cytokine profile." | 3.91 | Prolactin Induces IL-2 Associated TRAIL Expression on Natural Killer Cells from Chronic Hepatitis C Patients ( Bernal, AR; Cordova, J; Garcia, AP; Hernández, J; Kershenobich, D; Luna, JS; Medel, MLH; Mummidi, S; Parra, A; Porras, LM; Reyes, GG, 2019) |
| " He was diagnosed with oligozoospermia, asthenozoospermia and hyperprolactinemia probably induced by sulpiride for depression, because semen quality gradually improved after cessation of sulpiride administration." | 3.79 | [A case of male infertility caused by drug-induced hyperprolactinemia]. ( Iwasaki, A; Kato, Y; Kobayashi, M; Kuroda, S; Noguchi, K; Takeshima, T; Yumura, Y, 2013) |
| " We conducted this 6-month, parallel-group study to prospectively investigate the effects of the dopamine agonist cabergoline on sexual dysfunction in clinically stable patients with schizophrenia (DSM-IV, AP 194) and hyperprolactinemia (PRL > 20 ng/ml for men and PRL > 25 ng/ml for women)." | 3.79 | Effects of cabergoline on hyperprolactinemia, psychopathology, and sexual functioning in schizophrenic patients. ( Arvanitakis, P; Dimopoulou, K; Kalkavoura, CS; Lykouras, L; Michopoulos, I; Theodoropoulou, P; Tzebelikos, E, 2013) |
| "In this study, 11 healthy male subjects taking different doses of sulpiride and 24 male patients with DSM-IV-diagnosed schizophrenia taking different antipsychotic drugs (risperidone, olanzapine, haloperidol, and sulpiride) participated." | 3.76 | Positron emission tomography measurement of dopamine D₂ receptor occupancy in the pituitary and cerebral cortex: relation to antipsychotic-induced hyperprolactinemia. ( Arakawa, R; Ito, H; Maeda, J; Okubo, Y; Okumura, M; Suhara, T; Takahashi, H; Takano, A; Takano, H, 2010) |
| " To enhance PRL release, we induced hyperprolactinemia by administering chronic injections of sulpiride (40 mg." | 3.71 | Effects of hyperprolactinemia on rat prostate growth: evidence of androgeno-dependence. ( Ahidouch, A; Authie, D; Beauvillain, JC; Carpentier, F; Cousse, H; Croix, D; Dewailly, E; Dupouy, JP; Fournier, S; Le Bourhis, X; Legrand, G; Prevarskaya, N; Raynaud, JP; Slomianny, C; Van Coppenolle, F, 2001) |
| "We aimed to develop an anovulation model, using sulpiride-induced hyperprolactinemia in common marmosets." | 3.70 | New hyperprolactinemia and anovulation model in common marmoset (Callithrix jacchus) and effect of cabergoline. ( Inada, Y; Kojima, M; Komatsu, H; Miyata, H; Moro, M; Torii, R, 1999) |
| "005) by sulpiride-induced hyperprolactinaemia." | 3.67 | Inhibition of ovulation, steroidogenesis and collagenolytic activity in rabbits by sulpiride-induced hyperprolactinaemia. ( Kawamura, N; Lin, KC; Mori, T; Okamura, H, 1988) |
| "The effect of a potent agonistic analog of LHRH, D-Trp6-LHRH, on hyperprolactinemia induced by sulpiride was studied in normal men." | 3.67 | D-Trp6-luteinizing hormone-releasing hormone inhibits sulpiride-induced hyperprolactinemia in normal men. ( Cabranes, JA; Calle, JR; Charro, AL; Rubio, MA; Schally, AV; Torres-Aleman, I, 1987) |
| "Hyperprolactinemia was experimentally produced in rats by administration of ovine prolactin (oPRL) and sulpiride, and tried to evaluate the effect of hyperprolactinemia on ovarian receptor for luteinizing hormone (LH) as well as that on serum gonadotropin and steroid hormone levels." | 3.67 | Modulation of ovarian LH receptor and serum hormone levels in rats with hyperprolactinemia induced by administration of ovine prolactin or sulpiride. ( Fukushima, M; Ota, H; Wakizaka, A, 1986) |
| "To clarify the possible direct effects of hyperprolactinemia on the ovulatory process, we experimentally established hyperprolactinemia in female rabbits with 4 daily injections of sulpiride (SLP) at different doses and induced ovulation with human chorionic gonadotropin (hCG)." | 3.67 | Inhibition of human chorionic gonadotropin-induced ovulation and steroidogenesis by short-term hyperprolactinemia in female rabbits. ( Lin, KC; Mori, T; Okamura, H, 1987) |
| "We investigated the influence of chronic (27-65 days) sulpiride-induced hyperprolactinemia on the menstrual cycles of four normal women." | 3.67 | Effects of chronic sulpiride-induced hyperprolactinemia on menstrual cycles of normal women. ( Aso, T; Morikawa, K; Motohashi, T; Oseko, F, 1988) |
| "A total of 111 patients with schizophrenia who were either started on or switched to amisulpride were assessed for prolactin levels and endocrine-related adverse effects using 6 items derived from the Liverpool University neuroleptic side-effect rating scale (LUNSERS) at baseline, 8 weeks, and 1 year." | 2.77 | Relationship between prolactin levels and subjective endocrine-related adverse effects in patients with schizophrenia receiving long-term treatment with amisulpride. ( Ahn, YM; Jung, DC; Kim, EY; Kim, SH; Kim, YS; Lee, NY, 2012) |
| "The mean dosage of amisulpride was 195." | 2.77 | Hyperprolactinemia induced by low-dosage amisulpride in Korean psychiatric patients. ( Kang, SG; Kim, TW; Lee, BH; Lee, HJ; Park, YM; Yoon, HK, 2012) |
| "Hyperprolactinemia is an important but neglected adverse effect of antipsychotic medication." | 2.73 | Time course of the changes in antipsychotic-induced hyperprolactinemia following the switch to aripiprazole. ( Chen, CH; Lu, ML; Shen, WW, 2008) |
| "The much lower prevalence of hyperprolactinaemia over 2 000 mIU/l differentiates olanzapine from amisulpride and risperidone." | 2.73 | Differences in the effect of second-generation antipsychotics on prolactinaemia: six weeks open-label trial in female in-patients. ( Cejpková, A; Rodáková, I; Svestka, J; Synek, O; Tomanová, J, 2007) |
| "Antipsychotic drugs are the mainstay of treatment in schizophrenia." | 1.35 | Hyperprolactinemia and possibly related development of prolactinoma during amisulpride treatment; three cases. ( Akkaya, C; Ersoy, C; Kaya, B; Kirli, S; Kotan, Z; Sarandol, A, 2009) |
| " However, increased implantation loss was observed at 10 mg/kg or more, which was considered to be caused by the adverse effect of sulpiride on oocyte development." | 1.35 | Collaborative work on evaluation of ovarian toxicity. 17) Two- or four-week repeated-dose studies and fertility study of sulpiride in female rats. ( Adachi, T; Inoue, Y; Ishii, S; Mutai, M; Okada, M; Sugimoto, J; Ube, M; Uno, Y, 2009) |
| " No significant correlation was detected between prolactin levels and either amisulpride dosage or duration of administration." | 1.34 | Amisulpride-induced hyperprolactinemia is reversible following discontinuation. ( Liappas, J; Mourikis, I; Paparrigopoulos, T; Soldatos, C; Tzavellas, E, 2007) |
| "Risperidone monotherapy treatment was associated with hyperprolactinaemia in 69% of patients ( n = 35) and in 100% of female patients (n = 16) and amisulpride monotherapy in 100% (n = 7)." | 1.34 | Prevalence of hyperprolactinaemia in a naturalistic cohort of schizophrenia and bipolar outpatients during treatment with typical and atypical antipsychotics. ( Bushe, C; Shaw, M, 2007) |
| " However, no correlation between prolactin levels and dosage could be found." | 1.32 | [Plasma prolactin level and incidence of adverse endocrinologic effects during therapy with atypical neuroleptics]. ( Fric, M; Laux, G, 2003) |
| "When there was a pituitary adenoma or supra-sellar lesion the PRL response to sulpiride was always less than 481%." | 1.28 | [The combined stimulation test sulpiride-TRH in the investigation of prolactin secretion]. ( Claustrat, F; Dechaud, H; Miras-Mirakian, P; Pugeat, M, 1992) |
| "The sulpiride-induced PRL increase was higher than that induced by TRH." | 1.27 | Prolactin dynamics in a patient with isolated ACTH deficiency accompanied by hyperprolactinemia. ( Shibutani, Y, 1988) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 14 (20.90) | 18.7374 |
| 1990's | 11 (16.42) | 18.2507 |
| 2000's | 24 (35.82) | 29.6817 |
| 2010's | 16 (23.88) | 24.3611 |
| 2020's | 2 (2.99) | 2.80 |
| Authors | Studies |
|---|---|
| Adán-Castro, E | 1 |
| Siqueiros-Márquez, L | 1 |
| Ramírez-Hernández, G | 1 |
| Díaz-Lezama, N | 1 |
| Ruíz-Herrera, X | 1 |
| Núñez, FF | 1 |
| Núñez-Amaro, CD | 1 |
| Robles-Osorio, ML | 1 |
| Bertsch, T | 1 |
| Triebel, J | 1 |
| Martínez de la Escalera, G | 1 |
| Clapp, C | 1 |
| das, B | 1 |
| Nadeem, S | 1 |
| Radojkovic, D | 2 |
| Pesic, M | 2 |
| Radojkovic, M | 1 |
| Dimic, D | 1 |
| Vukelic Nikolic, M | 1 |
| Jevtovic Stoimenov, T | 1 |
| Radenkovic, S | 1 |
| Velojic Golubovic, M | 1 |
| Radjenovic Petkovic, T | 1 |
| Antic, S | 1 |
| Medel, MLH | 1 |
| Reyes, GG | 1 |
| Porras, LM | 1 |
| Bernal, AR | 1 |
| Luna, JS | 1 |
| Garcia, AP | 1 |
| Cordova, J | 1 |
| Parra, A | 1 |
| Mummidi, S | 1 |
| Kershenobich, D | 1 |
| Hernández, J | 1 |
| Takeshima, T | 1 |
| Kuroda, S | 1 |
| Kobayashi, M | 1 |
| Kato, Y | 2 |
| Yumura, Y | 1 |
| Noguchi, K | 1 |
| Iwasaki, A | 1 |
| Voicu, V | 1 |
| Medvedovici, A | 1 |
| Ranetti, AE | 1 |
| Rădulescu, FŞ | 1 |
| Kalkavoura, CS | 1 |
| Michopoulos, I | 1 |
| Arvanitakis, P | 1 |
| Theodoropoulou, P | 1 |
| Dimopoulou, K | 1 |
| Tzebelikos, E | 1 |
| Lykouras, L | 1 |
| Andrade, C | 1 |
| Pasquini, M | 1 |
| Berardelli, I | 1 |
| Calabrò, F | 1 |
| Roselli, V | 1 |
| Hefner, S | 1 |
| Biondi, M | 1 |
| Ristić, T | 1 |
| Kutsuna, S | 1 |
| Mezaki, K | 1 |
| Nagamatsu, M | 1 |
| Kunimatsu, J | 1 |
| Yamamoto, K | 1 |
| Fujiya, Y | 1 |
| Mawatari, M | 1 |
| Takeshita, N | 1 |
| Hayakawa, K | 1 |
| Kanagawa, S | 1 |
| Ohmagari, N | 1 |
| Akkaya, C | 1 |
| Kaya, B | 1 |
| Kotan, Z | 1 |
| Sarandol, A | 1 |
| Ersoy, C | 1 |
| Kirli, S | 1 |
| Lu, ML | 2 |
| Shen, WW | 1 |
| Chen, CH | 2 |
| Chen, YY | 1 |
| Huang, MC | 2 |
| Wu, KC | 1 |
| Saitis, M | 1 |
| Papazisis, G | 1 |
| Katsigiannopoulos, K | 1 |
| Kouvelas, D | 1 |
| Ishii, S | 1 |
| Ube, M | 1 |
| Okada, M | 1 |
| Adachi, T | 1 |
| Sugimoto, J | 1 |
| Inoue, Y | 1 |
| Uno, Y | 1 |
| Mutai, M | 1 |
| Tschoner, A | 1 |
| Engl, J | 1 |
| Rettenbacher, MA | 1 |
| Kaser, S | 1 |
| Ott, HW | 1 |
| Fleischhacker, WW | 1 |
| Patsch, JR | 1 |
| Ebenbichler, CF | 1 |
| Peitl, MV | 1 |
| Pavlović, E | 1 |
| Peitl, A | 1 |
| Peitl, V | 1 |
| Arakawa, R | 1 |
| Okumura, M | 1 |
| Ito, H | 1 |
| Takano, A | 1 |
| Takahashi, H | 1 |
| Takano, H | 1 |
| Maeda, J | 1 |
| Okubo, Y | 1 |
| Suhara, T | 1 |
| Höfer, P | 1 |
| Friedrich, F | 1 |
| Vyssoki, B | 1 |
| Spindelegger, C | 1 |
| Schmook, M | 1 |
| Barnas, C | 1 |
| Lesch, OM | 1 |
| Walter, H | 1 |
| Ružić, K | 1 |
| Grahovac, T | 1 |
| Graovac, M | 1 |
| Dadić-Hero, E | 1 |
| Sepić-Grahovac, D | 1 |
| Sabljić, V | 1 |
| Lee, BH | 1 |
| Kang, SG | 1 |
| Kim, TW | 1 |
| Lee, HJ | 1 |
| Yoon, HK | 1 |
| Park, YM | 1 |
| Kim, EY | 1 |
| Kim, SH | 1 |
| Lee, NY | 1 |
| Jung, DC | 1 |
| Kim, YS | 1 |
| Ahn, YM | 1 |
| Lee, SJ | 1 |
| Lee, JH | 1 |
| Jung, SW | 1 |
| Koo, BH | 1 |
| Choi, TY | 1 |
| Lee, KH | 1 |
| Marchese, G | 2 |
| Ruiu, S | 2 |
| Casti, P | 2 |
| Saba, P | 2 |
| Gessa, GL | 2 |
| Pani, L | 2 |
| Fric, M | 1 |
| Laux, G | 1 |
| Bressan, RA | 1 |
| Erlandsson, K | 1 |
| Spencer, EP | 1 |
| Ell, PJ | 1 |
| Pilowsky, LS | 1 |
| Bliesener, N | 1 |
| Yokusoglu, H | 1 |
| Quednow, BB | 1 |
| Klingmüller, D | 1 |
| Kühn, KU | 1 |
| Kopecek, M | 2 |
| Bares, M | 2 |
| Svarc, J | 1 |
| Dockery, C | 1 |
| Horácek, J | 2 |
| Paparrigopoulos, T | 1 |
| Liappas, J | 1 |
| Tzavellas, E | 1 |
| Mourikis, I | 1 |
| Soldatos, C | 1 |
| Paulzen, M | 1 |
| Gründer, G | 1 |
| Peritogiannis, V | 1 |
| Goulia, P | 1 |
| Pappas, D | 1 |
| Hyphantis, T | 1 |
| Mavreas, V | 1 |
| Bushe, C | 1 |
| Shaw, M | 1 |
| Svestka, J | 1 |
| Synek, O | 1 |
| Tomanová, J | 1 |
| Rodáková, I | 1 |
| Cejpková, A | 1 |
| Anderson, GM | 1 |
| Kieser, DC | 1 |
| Steyn, FJ | 1 |
| Grattan, DR | 1 |
| Sánchez, P | 1 |
| Torres, JM | 1 |
| Vílchez, P | 1 |
| Del Moral, RG | 1 |
| Ortega, E | 1 |
| Knoepfelmacher, M | 1 |
| Villares, SM | 1 |
| Nicolau, W | 1 |
| Germek, OO | 1 |
| Lerário, AC | 1 |
| Wajchenberg, BL | 1 |
| Liberman, B | 1 |
| Marín-López, G | 1 |
| Vílchez-Martínez, J | 1 |
| Hernández-Yañez, L | 1 |
| Torres-Morales, A | 1 |
| Bishop, W | 1 |
| Azuma, K | 1 |
| Irahara, M | 1 |
| Aono, T | 1 |
| Moro, M | 1 |
| Inada, Y | 1 |
| Kojima, M | 1 |
| Miyata, H | 1 |
| Komatsu, H | 1 |
| Torii, R | 1 |
| Baptista, T | 1 |
| Oliveira, MC | 1 |
| Messinger, HP | 1 |
| Tannhauser, M | 1 |
| Barbosa-Coutinho, L | 1 |
| Van Coppenolle, F | 1 |
| Slomianny, C | 1 |
| Carpentier, F | 1 |
| Le Bourhis, X | 1 |
| Ahidouch, A | 1 |
| Croix, D | 1 |
| Legrand, G | 1 |
| Dewailly, E | 1 |
| Fournier, S | 1 |
| Cousse, H | 1 |
| Authie, D | 1 |
| Raynaud, JP | 1 |
| Beauvillain, JC | 1 |
| Dupouy, JP | 1 |
| Prevarskaya, N | 1 |
| Roś, LT | 1 |
| Bartholini, F | 1 |
| Miras-Mirakian, P | 1 |
| Claustrat, F | 1 |
| Dechaud, H | 1 |
| Pugeat, M | 1 |
| Hattori, N | 1 |
| Ikekubo, K | 1 |
| Ishihara, T | 1 |
| Moridera, K | 1 |
| Hino, M | 1 |
| Kurahachi, H | 1 |
| Usuki, S | 1 |
| Ichikawa, Y | 1 |
| Kira, J | 1 |
| Harada, M | 1 |
| Yamaguchi, Y | 1 |
| Shida, N | 1 |
| Goto, I | 1 |
| Falaschi, P | 1 |
| Rosa, M | 1 |
| Rocco, A | 1 |
| D'Urso, R | 1 |
| Proietti, A | 1 |
| Melis, GB | 1 |
| Nakano, R | 4 |
| Nishi, T | 3 |
| Yagi, S | 2 |
| Shibutani, Y | 1 |
| Lin, KC | 2 |
| Kawamura, N | 1 |
| Okamura, H | 2 |
| Mori, T | 3 |
| Rubio, MA | 1 |
| Torres-Aleman, I | 1 |
| Calle, JR | 1 |
| Cabranes, JA | 1 |
| Schally, AV | 1 |
| Charro, AL | 1 |
| Ota, H | 1 |
| Wakizaka, A | 1 |
| Fukushima, M | 1 |
| Horie, K | 1 |
| Ban, C | 1 |
| Taii, S | 1 |
| Aso, T | 2 |
| Sowa, M | 1 |
| Tsuji, K | 1 |
| Oseko, F | 1 |
| Morikawa, K | 1 |
| Motohashi, T | 1 |
| Barguño, JM | 1 |
| del Pozo, E | 1 |
| Cruz, M | 1 |
| Figueras, J | 1 |
| Lewis, M | 1 |
| Howie, PW | 1 |
| Melloni, GF | 1 |
| Catenazzo, G | 1 |
| Torri, A | 1 |
| Fiorenza, AM | 1 |
| Melloni, R | 1 |
| Scarazatti, E | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Therapy With Bromocriptine in Patients With Symptomatic Risperidone-Induced Hyperprolactinemia[NCT00315081] | Phase 3 | 20 participants | Interventional | 2006-05-31 | Not yet recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
5 reviews available for sulpiride and Hyperprolactinemia
| Article | Year |
|---|---|
Drug-induced hypo- and hyperprolactinemia: mechanisms, clinical and therapeutic consequences.
Topics: Amisulpride; Antipsychotic Agents; Aripiprazole; Blood-Brain Barrier; Humans; Hyperprolactinemia; Is | 2013 |
Is amisulpride safe when prescribed to breast and prostate cancer patients?
Topics: Amisulpride; Antidepressive Agents; Breast Neoplasms; Depression; Female; Humans; Hyperprolactinemia | 2013 |
[Metoclopramide, sulpiride, and chlorpromazine loading test].
Topics: Chlorpromazine; Humans; Hyperprolactinemia; Metoclopramide; Pituitary Function Tests; Pituitary Glan | 1997 |
Body weight gain induced by antipsychotic drugs: mechanisms and management.
Topics: Animals; Antipsychotic Agents; Body Weight; Dose-Response Relationship, Drug; Endocrine System; Estr | 1999 |
[Changes in the endocrine system in the course of sulpiride therapy].
Topics: Antidepressive Agents, Second-Generation; Antipsychotic Agents; Depressive Disorder; Dopamine Antago | 2001 |
9 trials available for sulpiride and Hyperprolactinemia
| Article | Year |
|---|---|
Time course of the changes in antipsychotic-induced hyperprolactinemia following the switch to aripiprazole.
Topics: Adolescent; Adult; Analysis of Variance; Antipsychotic Agents; Aripiprazole; Cross-Over Studies; Dru | 2008 |
Hyperprolactinemia induced by low-dosage amisulpride in Korean psychiatric patients.
Topics: Adult; Amisulpride; Asian People; Dopamine Antagonists; Dose-Response Relationship, Drug; Female; Hu | 2012 |
Relationship between prolactin levels and subjective endocrine-related adverse effects in patients with schizophrenia receiving long-term treatment with amisulpride.
Topics: Adult; Amisulpride; Antipsychotic Agents; Drug Tolerance; Female; Humans; Hyperprolactinemia; Male; | 2012 |
A 6-week, randomized, multicentre, open-label study comparing efficacy and tolerability of amisulpride at a starting dose of 400 mg/day versus 800 mg/day in patients with acute exacerbations of schizophrenia.
Topics: Adult; Aged; Amisulpride; Analysis of Variance; Antipsychotic Agents; Chi-Square Distribution; Disea | 2012 |
Usefulness of bromocriptine in the treatment of amisulpride-induced hyperprolactinemia: a case report.
Topics: Adult; Amisulpride; Antipsychotic Agents; Bromocriptine; Estradiol; Female; Follicle Stimulating Hor | 2004 |
Hyperprolactinemia after low dose of amisulpride.
Topics: Adult; Amisulpride; Anti-Anxiety Agents; Antidepressive Agents; Antipsychotic Agents; Depression; Dr | 2004 |
Differences in the effect of second-generation antipsychotics on prolactinaemia: six weeks open-label trial in female in-patients.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Amisulpride; Antipsychotic Agents; Benzodiazepines; Dibe | 2007 |
Effect of ritanserin, specific 5HT-2 antagonist, on PRL secretion in normal subjects and in different hyperprolactinaemic conditions.
Topics: Adenoma; Female; Follicular Phase; Humans; Hyperprolactinemia; Piperidines; Pituitary Neoplasms; Pos | 1991 |
Failure of maintained hyperprolactinemia to improve lactational performance in late puerperium.
Topics: Adolescent; Adult; Body Weight; Female; Humans; Hyperprolactinemia; Infant, Newborn; Lactation; Post | 1988 |
53 other studies available for sulpiride and Hyperprolactinemia
| Article | Year |
|---|---|
Sulpiride-induced hyperprolactinaemia increases retinal vasoinhibin and protects against diabetic retinopathy in rats.
Topics: Animals; Diabetes Mellitus, Experimental; Diabetic Retinopathy; Humans; Hyperprolactinemia; Prolacti | 2022 |
Levosulpiride-induced Hyperprolactinemia.
Topics: Humans; Hyperprolactinemia; Sulpiride | 2020 |
Expression of prolactin receptors in the duodenum, kidneys and skeletal system during physiological and sulpiride-induced hyperprolactinaemia.
Topics: Animals; Bone and Bones; Calcium; Duodenum; Female; Hyperprolactinemia; Kidney; Osteocalcin; Parathy | 2018 |
Prolactin Induces IL-2 Associated TRAIL Expression on Natural Killer Cells from Chronic Hepatitis C Patients
Topics: Cells, Cultured; Cimetidine; Gene Expression; Hepatitis C, Chronic; Humans; Hyperprolactinemia; Inte | 2019 |
[A case of male infertility caused by drug-induced hyperprolactinemia].
Topics: Antidepressive Agents, Second-Generation; Humans; Hyperprolactinemia; Infertility, Male; Male; Middl | 2013 |
Effects of cabergoline on hyperprolactinemia, psychopathology, and sexual functioning in schizophrenic patients.
Topics: Adult; Amisulpride; Antipsychotic Agents; Cabergoline; Diagnostic and Statistical Manual of Mental D | 2013 |
Low-dose amisulpride and elevation in serum prolactin.
Topics: Dopamine Antagonists; Dose-Response Relationship, Drug; Humans; Hyperprolactinemia; Prolactin; Sulpi | 2013 |
Bone turnover markers in medicamentous and physiological hyperprolactinemia in female rats.
Topics: Animals; Biomarkers; Bone and Bones; Bone Density; Calcium; Female; Hyperprolactinemia; Osteocalcin; | 2014 |
Two Cases of Granulomatous Mastitis Caused by Corynebacterium kroppenstedtii Infection in Nulliparous Young Women with Hyperprolactinemia.
Topics: Adult; Anti-Bacterial Agents; Corynebacterium; Corynebacterium Infections; Drainage; Female; Granulo | 2015 |
Hyperprolactinemia and possibly related development of prolactinoma during amisulpride treatment; three cases.
Topics: Adult; Amisulpride; Antipsychotic Agents; Brain; Female; Humans; Hyperprolactinemia; Magnetic Resona | 2009 |
Weight gain in a patient with schizophrenia switched from quetiapine to amisulpride.
Topics: Adult; Amisulpride; Antipsychotic Agents; Appetite; Dibenzothiazepines; Dose-Response Relationship, | 2008 |
Aripiprazole resolves amisulpride and ziprasidone-induced hyperprolactinemia.
Topics: Amisulpride; Antipsychotic Agents; Aripiprazole; Female; Humans; Hyperprolactinemia; Long-Term Care; | 2008 |
Collaborative work on evaluation of ovarian toxicity. 17) Two- or four-week repeated-dose studies and fertility study of sulpiride in female rats.
Topics: Animals; Antipsychotic Agents; Body Weight; Drug Administration Schedule; Embryo, Mammalian; Embryon | 2009 |
Is second-generation antipsychotic-induced hyperprolactinemia due to biologically active prolactin or to biologically inactive macroprolactin? Results from a prospective study.
Topics: Adolescent; Adult; Amisulpride; Antipsychotic Agents; Diagnosis, Differential; Female; Humans; Hyper | 2009 |
Amenorrhoea - consequence of combined treatment with sulpiride and risperidone in a patient suffering from schizophrenia.
Topics: Amenorrhea; Antipsychotic Agents; Drug Therapy, Combination; Female; Humans; Hyperprolactinemia; Mid | 2010 |
Positron emission tomography measurement of dopamine D₂ receptor occupancy in the pituitary and cerebral cortex: relation to antipsychotic-induced hyperprolactinemia.
Topics: Adult; Antipsychotic Agents; Benzodiazepines; Carbon Radioisotopes; Cerebellar Cortex; Cerebral Cort | 2010 |
Hyperprolactinaemia and acute psychosis: prolactinoma or medication-induced phenomenon?
Topics: Amisulpride; Antipsychotic Agents; Benzodiazepines; Female; Follow-Up Studies; Humans; Hyperprolacti | 2010 |
Hyperprolactinaemia with amisulpride.
Topics: Amisulpride; Anti-Anxiety Agents; Antidepressive Agents; Antipsychotic Agents; Anxiety Disorders; Bo | 2011 |
Effect of the amisulpride isomers on rat prolactinemia.
Topics: Amisulpride; Animals; Dose-Response Relationship, Drug; Hyperprolactinemia; Male; Pituitary Gland; P | 2002 |
Drug-related hyperprolactinemia.
Topics: Antidepressive Agents; Antipsychotic Agents; Female; Flunarizine; Fluoxetine; Fluvoxamine; Humans; H | 2003 |
[Plasma prolactin level and incidence of adverse endocrinologic effects during therapy with atypical neuroleptics].
Topics: Adult; Amisulpride; Antipsychotic Agents; Benzodiazepines; Depressive Disorder, Major; Dibenzothiaze | 2003 |
Prolactinemia is uncoupled from central D2/D3 dopamine receptor occupancy in amisulpride treated patients.
Topics: Adult; Amisulpride; Antipsychotic Agents; Brain; Contrast Media; Dopamine D2 Receptor Antagonists; D | 2004 |
Normalization of hyperprolactinaemia after withdrawal of a low dose of amisulpride.
Topics: Adult; Amisulpride; Antipsychotic Agents; Depressive Disorder; Female; Humans; Hyperprolactinemia; M | 2005 |
Amisulpride-induced hyperprolactinemia is reversible following discontinuation.
Topics: Adult; Aged; Amisulpride; Antipsychotic Agents; Dose-Response Relationship, Drug; Female; Humans; Hy | 2007 |
Amisulpride-induced hyperprolactinaemia is not reversed by addition of aripiprazole.
Topics: Amisulpride; Antipsychotic Agents; Aripiprazole; Dopamine Agonists; Dopamine Antagonists; Drug Thera | 2007 |
Amenorrhea after sertraline introduction in an amisulpride-treated patient with undiagnosed polycystic ovary disease.
Topics: Adult; Amenorrhea; Amisulpride; Antipsychotic Agents; Depression; Drug Interactions; Female; Humans; | 2007 |
Prevalence of hyperprolactinaemia in a naturalistic cohort of schizophrenia and bipolar outpatients during treatment with typical and atypical antipsychotics.
Topics: Adult; Amisulpride; Antipsychotic Agents; Bipolar Disorder; Cohort Studies; Cross-Sectional Studies; | 2007 |
Aripiprazole resolves symptomatic hyperprolactinemia in a male schizophrenic patient.
Topics: Adult; Antipsychotic Agents; Aripiprazole; Humans; Hyperprolactinemia; Male; Piperazines; Quinolones | 2008 |
Hypothalamic prolactin receptor messenger ribonucleic acid levels, prolactin signaling, and hyperprolactinemic inhibition of pulsatile luteinizing hormone secretion are dependent on estradiol.
Topics: Animals; Estradiol; Female; Gonadotropin-Releasing Hormone; Hyperprolactinemia; Hypothalamus; Lutein | 2008 |
Effects of sulpiride on mRNA levels of steroid 5alpha-reductase isozymes in prostate of adult rats.
Topics: 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; Animals; Hyperprolactinemia; Isoenzymes; Male; Prolactin; Pro | 2008 |
Calcium and prolactin secretion in humans: effects of the channel blocker, verapamil, in the spontaneous and drug-induced hyperprolactinemia.
Topics: Adult; Calcium; Female; Humans; Hyperprolactinemia; Male; Prolactin; Prolactinoma; Sulpiride; Thyrot | 1994 |
[Leydig cell function in hyper- or hypoprolactinemic states in healthy men].
Topics: Adult; Bromocriptine; Chorionic Gonadotropin; Estradiol; Follicle Stimulating Hormone; Humans; Hyper | 1996 |
New hyperprolactinemia and anovulation model in common marmoset (Callithrix jacchus) and effect of cabergoline.
Topics: Animals; Anovulation; Bromocriptine; Cabergoline; Callithrix; Disease Models, Animal; Dopamine Agoni | 1999 |
Chronic effect of antidopaminergic drugs or estrogen on male wistar rat lactotrophs and somatotrophs.
Topics: Animals; Dopamine Antagonists; Estrogens; Fluphenazine; Growth Hormone; Haloperidol; Hyperprolactine | 1999 |
Effects of hyperprolactinemia on rat prostate growth: evidence of androgeno-dependence.
Topics: Animals; Apoptosis; Chronic Disease; Dihydrotestosterone; Dopamine Antagonists; Gonadal Steroid Horm | 2001 |
Carmoxirole is able to reduce amisulpride-induced hyperprolactinemia without affecting its central effect.
Topics: Amisulpride; Animals; Antipsychotic Agents; Binding, Competitive; Bromocriptine; Dopamine Agonists; | 2002 |
[The combined stimulation test sulpiride-TRH in the investigation of prolactin secretion].
Topics: Adenoma; Amenorrhea; Clinical Protocols; Diagnosis, Differential; Evaluation Studies as Topic; Femal | 1992 |
A normal ovulatory woman with hyperprolactinemia: presence of anti-prolactin autoantibody and the regulation of prolactin secretion.
Topics: Adult; Autoantibodies; Bromocriptine; Chromatography, Gel; Dopamine; Female; Humans; Hyperprolactine | 1992 |
Effects of hachimijiogan on dopamine, serotonin and vasoactive intestinal peptide in plasma and hypothalamus in sulpiride-induced hyperprolactinemic rats.
Topics: Animals; Bromocriptine; Dopamine; Drug Evaluation, Preclinical; Drugs, Chinese Herbal; Female; Hyper | 1991 |
Hyperprolactinemia in multiple sclerosis.
Topics: Adult; Bromocriptine; Dopamine; Female; Galactorrhea; Humans; Hyperprolactinemia; Hypothalamus; Levo | 1991 |
Progesterone feedback in normal and sulpiride-induced hyperprolactinemic postmenopausal women.
Topics: Aged; Aged, 80 and over; Ethinyl Estradiol; Feedback; Female; Follicle Stimulating Hormone; Humans; | 1989 |
Estrogen feedback in normal and sulpiride-induced hyperprolactinemic postmenopausal women.
Topics: Aged; Aged, 80 and over; Dose-Response Relationship, Drug; Ethinyl Estradiol; Feedback; Female; Foll | 1989 |
Prolactin dynamics in a patient with isolated ACTH deficiency accompanied by hyperprolactinemia.
Topics: Adrenocorticotropic Hormone; Aged; Humans; Hyperprolactinemia; Levodopa; Male; Prolactin; Sulpiride; | 1988 |
Inhibition of ovulation, steroidogenesis and collagenolytic activity in rabbits by sulpiride-induced hyperprolactinaemia.
Topics: Animals; Cathepsin H; Cathepsins; Chorionic Gonadotropin; Collagen; Cysteine Endopeptidases; Female; | 1988 |
D-Trp6-luteinizing hormone-releasing hormone inhibits sulpiride-induced hyperprolactinemia in normal men.
Topics: Follicle Stimulating Hormone; Gonadotropin-Releasing Hormone; Humans; Hyperprolactinemia; Luteinizin | 1987 |
Modulation of ovarian LH receptor and serum hormone levels in rats with hyperprolactinemia induced by administration of ovine prolactin or sulpiride.
Topics: Animals; Estradiol; Female; Follicle Stimulating Hormone; Hormones; Hyperprolactinemia; Kinetics; Lu | 1986 |
Impaired steroidogenic function of corpora lutea from hyperprolactinemic baboons induced by sulpiride.
Topics: Animals; Corpus Luteum; Disease Models, Animal; Estradiol; Female; Follicle Stimulating Hormone; Hyp | 1986 |
Effects of sulpiride-induced hyperprolactinemia on human ovarian follicles during the late follicular phase.
Topics: Adult; Estradiol; Female; Follicle Stimulating Hormone; Follicular Phase; Humans; Hyperprolactinemia | 1986 |
Inhibition of human chorionic gonadotropin-induced ovulation and steroidogenesis by short-term hyperprolactinemia in female rabbits.
Topics: Animals; Chorionic Gonadotropin; Female; Follicle Stimulating Hormone; Gonadal Steroid Hormones; Hyp | 1987 |
Effects of chronic sulpiride-induced hyperprolactinemia on menstrual cycles of normal women.
Topics: Adult; Amenorrhea; Female; Follicle Stimulating Hormone; Follicular Phase; Humans; Hyperprolactinemi | 1988 |
Pituitary and testicular response to luteinizing hormone releasing hormone in normal and sulpiride-induced hyperprolactinaemic men.
Topics: Adult; Follicle Stimulating Hormone; Gonadotropin-Releasing Hormone; Humans; Hyperprolactinemia; Lut | 1988 |
Induction of transient hyperprolactinaemia in neonatal rats by direct or maternal treatment with the dopamine receptor blocker, sulpiride.
Topics: Animals; Dose-Response Relationship, Drug; Female; Hyperprolactinemia; Injections, Intraperitoneal; | 1987 |
[Radio-hormonal study (radioimmunoassay) in young women with functional hyperprolactinemia. 1) Analysis in basal states].
Topics: Adult; Gonadotropin-Releasing Hormone; Humans; Hyperprolactinemia; Luteinizing Hormone; Nomifensine; | 1985 |