Page last updated: 2024-11-04

sulpiride and Galactorrhea

sulpiride has been researched along with Galactorrhea in 21 studies

Sulpiride: A dopamine D2-receptor antagonist. It has been used therapeutically as an antidepressant, antipsychotic, and as a digestive aid. (From Merck Index, 11th ed)
sulpiride : A member of the class of benzamides obtained from formal condensation between the carboxy group of 2-methoxy-5-sulfamoylbenzoic acid and the primary amino group of (1-ethylpyrrolidin-2-yl)methylamine.

Galactorrhea: Excessive or inappropriate LACTATION in females or males, and not necessarily related to PREGNANCY. Galactorrhea can occur either unilaterally or bilaterally, and be profuse or sparse. Its most common cause is HYPERPROLACTINEMIA.

Research Excerpts

ExcerptRelevanceReference
"The clinical courses of galactorrhea and menstrual disorders were studied in 18 women with galactorrhea induced by sulpiride (SLP) or metoclopramide (MCP) given for the treatment of gastrointestinal diseases."7.66Clinical and endocrinological analyses of patients with galactorrhea and menstrual disorders due to sulpiride or metoclopramide. ( Aono, T; Kinugasa, T; Kurachi, K; Onishi, T; Shioji, T, 1978)
"The clinical courses of galactorrhea and menstrual disorders were studied in 18 women with galactorrhea induced by sulpiride (SLP) or metoclopramide (MCP) given for the treatment of gastrointestinal diseases."3.66Clinical and endocrinological analyses of patients with galactorrhea and menstrual disorders due to sulpiride or metoclopramide. ( Aono, T; Kinugasa, T; Kurachi, K; Onishi, T; Shioji, T, 1978)
" sulpiride (a dopamine-receptor-blocking drug) led to a significant rise in plasma TSH in normal womem, in female patients with galactorrhoea, and, to a much more marked degree, in male and female patients with primary hypothyroidism."3.66Increased thyrotrophin secretion induced by sulpiride in man. ( Belforte, L; Camanni, F; Massara, F; Molinatti, GM; Vergano, V, 1978)
"Treatment with sulpiride or chlorpromazine resulted in a significant reduction of psychotic morbidity as estimated by CPRS and global ratings."2.65Clinical evaluation of sulpiride in schizophrenic patients--a double-blind comparison with chlorpromazine. ( Aberg-Wistedt, A; Bjerkenstedt, L; Björk, K; Gullberg, B; Härnryd, C; Oxenstierna, G; Sedvall, G; Wiesel, FA; Wik, G, 1984)
"The galactorrhea is one of the possible side effects of psychotropic drugs."1.33[Endocrine side effects among psychiatric patients treated with antipsychotics]. ( Kovács, G; Kovács, L, 2006)
"When there was a pituitary adenoma or supra-sellar lesion the PRL response to sulpiride was always less than 481%."1.28[The combined stimulation test sulpiride-TRH in the investigation of prolactin secretion]. ( Claustrat, F; Dechaud, H; Miras-Mirakian, P; Pugeat, M, 1992)

Research

Studies (21)

TimeframeStudies, this research(%)All Research%
pre-199013 (61.90)18.7374
1990's2 (9.52)18.2507
2000's4 (19.05)29.6817
2010's2 (9.52)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Pathania, M1
Malik, P1
Sharma, S1
Mendhekar, D1
Lohia, D1
Varol Tas, F1
Guvenir, T1
Ružić, K1
Grahovac, T1
Graovac, M1
Dadić-Hero, E1
Sepić-Grahovac, D1
Sabljić, V1
Dehning, S1
Riedel, M1
Müller, N1
Kovács, L1
Kovács, G1
Härnryd, C1
Bjerkenstedt, L1
Björk, K1
Gullberg, B1
Oxenstierna, G1
Sedvall, G1
Wiesel, FA1
Wik, G1
Aberg-Wistedt, A1
Onda, H1
Polatti, F1
Brambilla, A1
Mandelli, B1
Forgione, A1
Farrari, C1
Telloli, P1
Rampini, P1
Caldara, R1
D'Agata, R1
Aliffi, A1
Maugeri, G1
Mongioì, A1
Vicari, E1
Gulizia, S1
Massara, F2
Camanni, F2
Belforte, L2
Campagnoli, C1
Novi, RF1
Molinatti, GM2
Aono, T1
Shioji, T1
Kinugasa, T1
Onishi, T1
Kurachi, K1
Buvat, J2
Thomas, K1
Racadot, A1
Blacker, C1
Buvat-Herbaut, M1
Ferin, F1
Linquette, M1
Vergano, V1
Mancini, AM1
Aparicio, NJ1
Vargas, CA1
Debeljuk, L1
Guitelman, A1
Kato, Y1
Decroix-Blacker, C1
Legal, F1
Gasnault, JP1
Miras-Mirakian, P1
Claustrat, F1
Dechaud, H1
Pugeat, M1
Kira, J1
Harada, M1
Yamaguchi, Y1
Shida, N1
Goto, I1
Brient-Clabaux, J1

Reviews

1 review available for sulpiride and Galactorrhea

ArticleYear
[Determination of serum prolactin].
    Nihon rinsho. Japanese journal of clinical medicine, 1976, Volume: 34 suppl

    Topics: 5-Hydroxytryptophan; Amenorrhea; Brain Diseases; Chlorpromazine; Female; Galactorrhea; Humans; Hypot

1976

Trials

1 trial available for sulpiride and Galactorrhea

ArticleYear
Clinical evaluation of sulpiride in schizophrenic patients--a double-blind comparison with chlorpromazine.
    Acta psychiatrica Scandinavica. Supplementum, 1984, Volume: 311

    Topics: Adolescent; Adult; Benzodiazepines; Chlorpromazine; Clinical Trials as Topic; Double-Blind Method; D

1984

Other Studies

19 other studies available for sulpiride and Galactorrhea

ArticleYear
Good clinical history scores over extensive workup in unmasking a case of galactorrhoea.
    BMJ case reports, 2018, Apr-07, Volume: 2018

    Topics: Depression; Dyspepsia; Female; Galactorrhea; Helicobacter Infections; Humans; Pituitary Gland; Proto

2018
Amisulpride and galactorrhoea: delayed or withdrawal?
    The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry, 2009, Volume: 10, Issue:4 Pt 3

    Topics: Adult; Amisulpride; Antipsychotic Agents; Female; Galactorrhea; Humans; Receptors, Dopamine D2; Rece

2009
Amisulpride treatment of adolescent patients with schizophrenia or schizo-affective disorders.
    European child & adolescent psychiatry, 2009, Volume: 18, Issue:8

    Topics: Adolescent; Amisulpride; Antiparkinson Agents; Antipsychotic Agents; Biperiden; Dose-Response Relati

2009
Hyperprolactinaemia with amisulpride.
    Psychiatria Danubina, 2011, Volume: 23, Issue:1

    Topics: Amisulpride; Anti-Anxiety Agents; Antidepressive Agents; Antipsychotic Agents; Anxiety Disorders; Bo

2011
Aripiprazole in a patient vulnerable to side effects.
    The American journal of psychiatry, 2005, Volume: 162, Issue:3

    Topics: Adult; Amenorrhea; Amisulpride; Antipsychotic Agents; Aripiprazole; Female; Galactorrhea; Humans; Pi

2005
[Endocrine side effects among psychiatric patients treated with antipsychotics].
    Neuropsychopharmacologia Hungarica : a Magyar Pszichofarmakologiai Egyesulet lapja = official journal of the Hungarian Association of Psychopharmacology, 2006, Volume: 8, Issue:2

    Topics: Adult; Amisulpride; Antipsychotic Agents; Aripiprazole; Benzodiazepines; Breast; Dibenzothiazepines;

2006
[A clinical study on the characteristics of galactorrhea-amenorrhea (especially of drug-induced galactorrhea-amenorrhea].
    Nihon Sanka Fujinka Gakkai zasshi, 1984, Volume: 36, Issue:10

    Topics: Amenorrhea; Animals; Estradiol; Female; Follicle Stimulating Hormone; Galactorrhea; Humans; Lactatio

1984
Can pharmacologic hyperprolactinemia and breast-suction induce lactation in women with normal menstrual cycles?
    Clinical and experimental obstetrics & gynecology, 1984, Volume: 11, Issue:4

    Topics: Adult; Female; Galactorrhea; Humans; Lactation; Lactation Disorders; Menstrual Cycle; Postpartum Per

1984
Hyperprolactinemic primary amenorrhea: case report with successful prolactin-lowering treatment and review of the literature.
    Gynecologic and obstetric investigation, 1980, Volume: 11, Issue:6

    Topics: Adult; Amenorrhea; Bromocriptine; Ergolines; Female; Follicle Stimulating Hormone; Galactorrhea; Hum

1980
Dynamics of Prl release in galactorrhoeic normoprolactinaemic women.
    Acta endocrinologica, 1982, Volume: 101, Issue:1

    Topics: Adult; Female; Galactorrhea; Humans; Hypothalamo-Hypophyseal System; Lactation Disorders; Pregnancy;

1982
Effect of sulpiride on plasma prolactin levels in women with puerperal or pathological hyperprolactinaemia.
    Acta endocrinologica, 1980, Volume: 95, Issue:2

    Topics: Adult; Amenorrhea; Female; Galactorrhea; Humans; Lactation Disorders; Pituitary Neoplasms; Pregnancy

1980
Clinical and endocrinological analyses of patients with galactorrhea and menstrual disorders due to sulpiride or metoclopramide.
    The Journal of clinical endocrinology and metabolism, 1978, Volume: 47, Issue:3

    Topics: Adult; Female; Follicle Stimulating Hormone; Galactorrhea; Gastrointestinal Diseases; Gonadotropin-R

1978
Changes in pituitary gonadotropins during the amenorrhoea-galactorrhoea syndrome due to sulpiride.
    Clinical endocrinology, 1978, Volume: 9, Issue:6

    Topics: Amenorrhea; Female; Follicle Stimulating Hormone; Galactorrhea; Gonadotropin-Releasing Hormone; Gona

1978
Increased thyrotrophin secretion induced by sulpiride in man.
    Clinical endocrinology, 1978, Volume: 9, Issue:5

    Topics: Adolescent; Adult; Female; Galactorrhea; Humans; Hypothyroidism; Male; Middle Aged; Pregnancy; Prola

1978
Serum levels of prolactin under basal conditions and after administration of sulpiride in normal and galactorrheic women.
    Fertility and sterility, 1978, Volume: 29, Issue:4

    Topics: Adenoma, Chromophobe; Adolescent; Adult; Amenorrhea; Female; Galactorrhea; Humans; Lactation Disorde

1978
[One thousand months of contraception with sulpiride].
    Revue francaise de gynecologie et d'obstetrique, 1976, Volume: 71, Issue:1

    Topics: Adolescent; Adult; Body Weight; Breast; Contraception; Drug Evaluation; Endometrium; Female; Galacto

1976
[The combined stimulation test sulpiride-TRH in the investigation of prolactin secretion].
    Journal de gynecologie, obstetrique et biologie de la reproduction, 1992, Volume: 21, Issue:4

    Topics: Adenoma; Amenorrhea; Clinical Protocols; Diagnosis, Differential; Evaluation Studies as Topic; Femal

1992
Hyperprolactinemia in multiple sclerosis.
    Journal of the neurological sciences, 1991, Volume: 102, Issue:1

    Topics: Adult; Bromocriptine; Dopamine; Female; Galactorrhea; Humans; Hyperprolactinemia; Hypothalamus; Levo

1991
[Agreal: its acceptibility. Review of the literature].
    Revue francaise de gynecologie et d'obstetrique, 1985, Feb-28, Volume: 80, Issue:3

    Topics: Adult; Female; Follicle Stimulating Hormone; Galactorrhea; Humans; Luteinizing Hormone; Menopause; M

1985