sulpiride has been researched along with Dyspepsia in 17 studies
Sulpiride: A dopamine D2-receptor antagonist. It has been used therapeutically as an antidepressant, antipsychotic, and as a digestive aid. (From Merck Index, 11th ed)
sulpiride : A member of the class of benzamides obtained from formal condensation between the carboxy group of 2-methoxy-5-sulfamoylbenzoic acid and the primary amino group of (1-ethylpyrrolidin-2-yl)methylamine.
Dyspepsia: Impaired digestion, especially after eating.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Sulpiride and itopride are effective in the treatment of dyspepsia in the form of postprandial distress syndrome." | 9.19 | [Efficacy of sulpiride and itopride in the treatment of functional dyspepsia in women with emotional and eating disorders]. ( Chojnacki, C; Klupińska, G; Pawłowicz, M; Wachowska-Kelly, P; Walecka-Kapica, E; Wojtkiewicz, P, 2014) |
| " The aim of the study is to compare the clinical efficacy of levosulpiride and cisapride in patients with dysmotility-like functional dyspepsia." | 9.11 | Levosulpiride and cisapride in the treatment of dysmotility-like functional dyspepsia: a randomized, double-masked trial. ( Balboa, A; Jiménez, I; Mearin, F; Patón, C; Pérez-Mota, A; Rodrigo, L; Sebastián, JJ, 2004) |
| "To compare the effects of chronic oral administration of cisapride and levosulpiride in patients with functional dyspepsia and delayed gastric emptying." | 9.09 | Comparative effects of levosulpiride and cisapride on gastric emptying and symptoms in patients with functional dyspepsia and gastroparesis. ( Biagini, R; Borro, P; Giacomini, M; Mansi, C; Mele, MR; Pandolfo, N; Savarino, V, 2000) |
| "Our study first demonstrates that levosulpiride has an accelerating effect on the emptying of solids from the stomach of patients with diabetic gastroparesis." | 9.08 | Gastrokinetic effects of levosulpiride in dyspeptic patients with diabetic gastroparesis. ( De Martini, D; Mansi, C; Mela, GS; Melga, P; Perilli, D; Savarino, V; Sciabà, L; Vigneri, S, 1995) |
| "Levosulpiride is effective and well tolerated in patients with functional dyspepsia accompanied by delayed gastric emptying." | 9.08 | Effects of levosulpiride in patients with functional dyspepsia accompanied by delayed gastric emptying. ( Choe, JG; Chun, HJ; Hyun, JH; Kim, CD; Ryu, HS; Song, CW, 1998) |
| "Our results showed that levosulpiride can be usefully employed in patients affected by functional dyspepsia." | 9.07 | The effects of levosulpiride on gastric and gall-bladder emptying in functional dyspepsia. ( Arienti, V; Biagi, F; Boriani, L; Corazza, GR; Gasbarrini, G; Maconi, G; Sorge, M; Sottili, S; Ugenti, F; Van Thiel, DH, 1994) |
| "Levosulpiride, a dopaminergic antagonist was compared in a double-blind randomized study with domperidone for treatment of functional dyspepsia in 50 patients divided into two groups of 25 subjects each." | 9.07 | [Levosulpiride versus domperidone in the treatment of functional dyspepsia]. ( Blasi, A; Brogna, A; Catanzaro, R; Mangiameli, A; Sofia, M, 1994) |
| "Fifty patients suffering from functional dyspepsia have been treated in a double-blind study either with 1-sulpiride (75 mg die per os) or with metoclopramide (30 mg die per os) for 30 days." | 9.07 | [L-sulpiride versus metoclopramide in functional dyspepsia: a randomized double-blind study]. ( Biasi, L; Brunelli, E; Macarri, G; Marucci, L; Svegliati Baroni, G, 1992) |
| "Levosulpiride is a sulpiride isomer that exerts its prokinetic action through a dual mechanism: 1) as a D(2) dopamine receptor antagonist and 2) as a serotonin 5HT(4) receptor agonist, conferring this drug with a cholinergic effect." | 6.46 | [Levosulpiride in the management of functional dyspepsia and delayed gastric emptying]. ( Serra, J, 2010) |
| "Sulpiride and itopride are effective in the treatment of dyspepsia in the form of postprandial distress syndrome." | 5.19 | [Efficacy of sulpiride and itopride in the treatment of functional dyspepsia in women with emotional and eating disorders]. ( Chojnacki, C; Klupińska, G; Pawłowicz, M; Wachowska-Kelly, P; Walecka-Kapica, E; Wojtkiewicz, P, 2014) |
| " The aim of the study is to compare the clinical efficacy of levosulpiride and cisapride in patients with dysmotility-like functional dyspepsia." | 5.11 | Levosulpiride and cisapride in the treatment of dysmotility-like functional dyspepsia: a randomized, double-masked trial. ( Balboa, A; Jiménez, I; Mearin, F; Patón, C; Pérez-Mota, A; Rodrigo, L; Sebastián, JJ, 2004) |
| "To compare the effects of chronic oral administration of cisapride and levosulpiride in patients with functional dyspepsia and delayed gastric emptying." | 5.09 | Comparative effects of levosulpiride and cisapride on gastric emptying and symptoms in patients with functional dyspepsia and gastroparesis. ( Biagini, R; Borro, P; Giacomini, M; Mansi, C; Mele, MR; Pandolfo, N; Savarino, V, 2000) |
| "Our study first demonstrates that levosulpiride has an accelerating effect on the emptying of solids from the stomach of patients with diabetic gastroparesis." | 5.08 | Gastrokinetic effects of levosulpiride in dyspeptic patients with diabetic gastroparesis. ( De Martini, D; Mansi, C; Mela, GS; Melga, P; Perilli, D; Savarino, V; Sciabà, L; Vigneri, S, 1995) |
| "Levosulpiride is effective and well tolerated in patients with functional dyspepsia accompanied by delayed gastric emptying." | 5.08 | Effects of levosulpiride in patients with functional dyspepsia accompanied by delayed gastric emptying. ( Choe, JG; Chun, HJ; Hyun, JH; Kim, CD; Ryu, HS; Song, CW, 1998) |
| "Our results showed that levosulpiride can be usefully employed in patients affected by functional dyspepsia." | 5.07 | The effects of levosulpiride on gastric and gall-bladder emptying in functional dyspepsia. ( Arienti, V; Biagi, F; Boriani, L; Corazza, GR; Gasbarrini, G; Maconi, G; Sorge, M; Sottili, S; Ugenti, F; Van Thiel, DH, 1994) |
| "Levosulpiride, a dopaminergic antagonist was compared in a double-blind randomized study with domperidone for treatment of functional dyspepsia in 50 patients divided into two groups of 25 subjects each." | 5.07 | [Levosulpiride versus domperidone in the treatment of functional dyspepsia]. ( Blasi, A; Brogna, A; Catanzaro, R; Mangiameli, A; Sofia, M, 1994) |
| "Fifty patients suffering from functional dyspepsia have been treated in a double-blind study either with 1-sulpiride (75 mg die per os) or with metoclopramide (30 mg die per os) for 30 days." | 5.07 | [L-sulpiride versus metoclopramide in functional dyspepsia: a randomized double-blind study]. ( Biasi, L; Brunelli, E; Macarri, G; Marucci, L; Svegliati Baroni, G, 1992) |
| " Evaluation revealed levosulpiride, a dopamine receptor blocker commonly used for dyspepsia, to be the culprit." | 3.91 | An Unusual Cause of Camptocormia. ( Kumar, R; Lal, V; Mehta, S, 2019) |
| "Cisapride was significantly more effective than lansoprazole (OR 0." | 2.82 | Comparative Efficacy of Various Pharmacological Interventions in the Treatment of Functional Dyspepsia: A Network Meta-Analysis. ( Liang, L; Wang, G; Xiao, L; Yu, J, 2022) |
| "Functional dyspepsia is defined as a group of symptoms, whether related or unrelated to intake, localized in the upper abdomen, that manifest in the form of discomfort or epigastric pain, postprandial fullness and early satiety, in the absence of any demonstrable organic or structural anomaly." | 2.50 | [Integrative medicine in the management of functional dyspepsia. Role of the herbal preparation STW5]. ( Sebastián-Domingo, JJ, 2014) |
| "Levosulpiride is a sulpiride isomer that exerts its prokinetic action through a dual mechanism: 1) as a D(2) dopamine receptor antagonist and 2) as a serotonin 5HT(4) receptor agonist, conferring this drug with a cholinergic effect." | 2.46 | [Levosulpiride in the management of functional dyspepsia and delayed gastric emptying]. ( Serra, J, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (5.88) | 18.7374 |
| 1990's | 5 (29.41) | 18.2507 |
| 2000's | 4 (23.53) | 29.6817 |
| 2010's | 6 (35.29) | 24.3611 |
| 2020's | 1 (5.88) | 2.80 |
| Authors | Studies |
|---|---|
| Liang, L | 1 |
| Yu, J | 1 |
| Xiao, L | 1 |
| Wang, G | 1 |
| Pathania, M | 1 |
| Malik, P | 1 |
| Sharma, S | 1 |
| Mehta, S | 1 |
| Kumar, R | 1 |
| Lal, V | 1 |
| Sebastián-Domingo, JJ | 1 |
| Wachowska-Kelly, P | 1 |
| Walecka-Kapica, E | 1 |
| Wojtkiewicz, P | 1 |
| Pawłowicz, M | 1 |
| Klupińska, G | 1 |
| Chojnacki, C | 1 |
| Kim, HJ | 1 |
| Cho, JY | 1 |
| Cho, YJ | 1 |
| Hong, KS | 1 |
| Serra, J | 1 |
| Lim, HC | 1 |
| Lee, SI | 1 |
| Chen, JD | 1 |
| Park, H | 1 |
| Mearin, F | 1 |
| Rodrigo, L | 1 |
| Pérez-Mota, A | 1 |
| Balboa, A | 1 |
| Jiménez, I | 1 |
| Sebastián, JJ | 1 |
| Patón, C | 1 |
| Morini, A | 1 |
| Mauceri, P | 1 |
| Pallotta, P | 1 |
| Pelliccia, G | 1 |
| Mansi, C | 2 |
| Savarino, V | 2 |
| Vigneri, S | 1 |
| Perilli, D | 1 |
| Melga, P | 1 |
| Sciabà, L | 1 |
| De Martini, D | 1 |
| Mela, GS | 1 |
| Arienti, V | 1 |
| Corazza, GR | 1 |
| Sorge, M | 1 |
| Boriani, L | 1 |
| Ugenti, F | 1 |
| Biagi, F | 1 |
| Maconi, G | 1 |
| Sottili, S | 1 |
| Van Thiel, DH | 1 |
| Gasbarrini, G | 1 |
| Mangiameli, A | 1 |
| Brogna, A | 1 |
| Catanzaro, R | 1 |
| Sofia, M | 1 |
| Blasi, A | 1 |
| Song, CW | 1 |
| Chun, HJ | 1 |
| Kim, CD | 1 |
| Ryu, HS | 1 |
| Choe, JG | 1 |
| Hyun, JH | 1 |
| Borro, P | 1 |
| Giacomini, M | 1 |
| Biagini, R | 1 |
| Mele, MR | 1 |
| Pandolfo, N | 1 |
| Distrutti, E | 1 |
| Fiorucci, S | 1 |
| Hauer, SK | 1 |
| Pensi, MO | 1 |
| Vanasia, M | 1 |
| Morelli, A | 1 |
| Macarri, G | 1 |
| Biasi, L | 1 |
| Brunelli, E | 1 |
| Marucci, L | 1 |
| Svegliati Baroni, G | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Multi-dimensional Clinical and Pathophysiological Profiles of Patients With Functional Dyspepsia and Effect of Gut Microbiota Manipulation Using Rifaximin for Its Treatment: A Randomized Controlled Trial[NCT04302402] | Phase 2 | 132 participants (Anticipated) | Interventional | 2020-03-31 | Not yet recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 reviews available for sulpiride and Dyspepsia
| Article | Year |
|---|---|
Comparative Efficacy of Various Pharmacological Interventions in the Treatment of Functional Dyspepsia: A Network Meta-Analysis.
Topics: Cisapride; Comparative Effectiveness Research; Dyspepsia; Gastrointestinal Agents; Humans; Network M | 2022 |
[Integrative medicine in the management of functional dyspepsia. Role of the herbal preparation STW5].
Topics: Algorithms; Anti-Anxiety Agents; Anti-Bacterial Agents; Anti-Inflammatory Agents; Antidepressive Age | 2014 |
[Levosulpiride in the management of functional dyspepsia and delayed gastric emptying].
Topics: Animals; Clinical Trials as Topic; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Drug Eval | 2010 |
10 trials available for sulpiride and Dyspepsia
| Article | Year |
|---|---|
[Efficacy of sulpiride and itopride in the treatment of functional dyspepsia in women with emotional and eating disorders].
Topics: Aged; Anxiety Disorders; Benzamides; Benzyl Compounds; Depression; Dopamine Antagonists; Dyspepsia; | 2014 |
Electrogastrography associated with symptomatic changes after prokinetic drug treatment for functional dyspepsia.
Topics: Adult; Aged; Benzamides; Benzyl Compounds; Dyspepsia; Electrodiagnosis; Female; Gastrointestinal Age | 2012 |
Levosulpiride and cisapride in the treatment of dysmotility-like functional dyspepsia: a randomized, double-masked trial.
Topics: Administration, Oral; Adolescent; Adult; Aged; Cisapride; Dose-Response Relationship, Drug; Double-B | 2004 |
Gastrokinetic effects of levosulpiride in dyspeptic patients with diabetic gastroparesis.
Topics: Cross-Over Studies; Diabetes Mellitus, Type 1; Dopamine Antagonists; Double-Blind Method; Dyspepsia; | 1995 |
The effects of levosulpiride on gastric and gall-bladder emptying in functional dyspepsia.
Topics: Adult; Aged; Aged, 80 and over; Double-Blind Method; Dyspepsia; Female; Gallbladder Emptying; Gastri | 1994 |
[Levosulpiride versus domperidone in the treatment of functional dyspepsia].
Topics: Adult; Benzamides; Domperidone; Dopamine Agents; Double-Blind Method; Dyspepsia; Female; Gastric Emp | 1994 |
Effects of levosulpiride in patients with functional dyspepsia accompanied by delayed gastric emptying.
Topics: Adolescent; Adult; Double-Blind Method; Dyspepsia; Female; Gastric Emptying; Gastrointestinal Agents | 1998 |
Comparative effects of levosulpiride and cisapride on gastric emptying and symptoms in patients with functional dyspepsia and gastroparesis.
Topics: Activities of Daily Living; Administration, Oral; Adult; Aged; Anti-Ulcer Agents; Cisapride; Cross-O | 2000 |
Effect of acute and chronic levosulpiride administration on gastric tone and perception in functional dyspepsia.
Topics: Adult; Double-Blind Method; Drug Administration Schedule; Dyspepsia; Female; Gastric Emptying; Gastr | 2002 |
[L-sulpiride versus metoclopramide in functional dyspepsia: a randomized double-blind study].
Topics: Adult; Aged; Double-Blind Method; Dyspepsia; Female; Humans; Male; Metoclopramide; Middle Aged; Sulp | 1992 |
4 other studies available for sulpiride and Dyspepsia
| Article | Year |
|---|---|
Good clinical history scores over extensive workup in unmasking a case of galactorrhoea.
Topics: Depression; Dyspepsia; Female; Galactorrhea; Helicobacter Infections; Humans; Pituitary Gland; Proto | 2018 |
An Unusual Cause of Camptocormia.
Topics: Aged; Brain; Diabetes Complications; Diagnosis, Differential; Dopamine Antagonists; Dyspepsia; Femal | 2019 |
Levosulpiride-induced resting orolingual tremor.
Topics: Dopamine Antagonists; Dyskinesia, Drug-Induced; Dyspepsia; Facial Muscles; Female; Humans; Middle Ag | 2009 |
[Irritable colon and psychosomatic disease].
Topics: Antidepressive Agents, Tricyclic; Benzodiazepines; Colitis; Colonic Diseases, Functional; Dyspepsia; | 1984 |