Page last updated: 2024-11-04

sulpiride and Drug Overdose

sulpiride has been researched along with Drug Overdose in 9 studies

Sulpiride: A dopamine D2-receptor antagonist. It has been used therapeutically as an antidepressant, antipsychotic, and as a digestive aid. (From Merck Index, 11th ed)
sulpiride : A member of the class of benzamides obtained from formal condensation between the carboxy group of 2-methoxy-5-sulfamoylbenzoic acid and the primary amino group of (1-ethylpyrrolidin-2-yl)methylamine.

Drug Overdose: Accidental or deliberate use of a medication or street drug in excess of normal dosage.

Research Excerpts

ExcerptRelevanceReference
"There was 1 case of torsade de pointes in a thioridazine overdose."1.42Prolonged QT Risk Assessment in Antipsychotic Overdose Using the QT Nomogram. ( Berling, I; Isbister, GK, 2015)
" They point out that the absorption rate is similar and the elimination is prorogated in sulpiride acute poisoning compared to therapeutic doses."1.37[Sulpiride poisoning--case report confirmed with the quantitative determination of the xenobiotic serum level]. ( Ciszowski, K; Groszek, B; Szpak, D; Wilimowska, J, 2011)
"Amisulpride is used for the treatment of schizophrenia and part of its safety profile is that is has no effect on the QT interval in therapeutic doses."1.36Amisulpride overdose: suggested management of prolonged QTc. ( Stevenson, RJ, 2010)
"One patient died of pulmonary edema and subsequent heart failure, but the rest of the patients recovered without any sequelae."1.34Hemoperfusion in the treatment of acute clozapine intoxication in China. ( Cai, ZJ; He, JL; Li, WB; Ungvari, GS; Xiang, YT, 2007)
"Although clinical trials of the antipsychotic amisulpride revealed no cardiac adverse effects, four patients with severe cardiac toxicity after overdose were reported to Australian poisons information centres in 2004-2005."1.33Amisulpride deliberate self-poisoning causing severe cardiac toxicity including QT prolongation and torsades de pointes. ( Daly, F; Gosselin, S; Hackett, LP; Haider, T; Isbister, GK; John, S; Murray, L; O'Mullane, P, 2006)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (33.33)29.6817
2010's6 (66.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Berling, I1
Isbister, GK4
Barceló, B1
Yates, C1
Castanyer, B1
Puiguriguer, J1
Balit, CR1
Macleod, D1
Duffull, SB2
Stevenson, RJ1
Joy, JP1
Coulter, CV1
Ciszowski, K1
Szpak, D1
Wilimowska, J1
Groszek, B1
Murray, L1
John, S1
Hackett, LP1
Haider, T1
O'Mullane, P1
Gosselin, S1
Daly, F1
He, JL1
Xiang, YT1
Li, WB1
Cai, ZJ1
Ungvari, GS1
Teoh, R1
Page, AV1
Hardern, R1

Other Studies

9 other studies available for sulpiride and Drug Overdose

ArticleYear
Prolonged QT Risk Assessment in Antipsychotic Overdose Using the QT Nomogram.
    Annals of emergency medicine, 2015, Volume: 66, Issue:2

    Topics: Adolescent; Adult; Aged; Amisulpride; Antipsychotic Agents; Drug Overdose; Electrocardiography; Fema

2015
[Prolonged QT interval in two cases of amisulpride overdose].
    Medicina clinica, 2010, Apr-24, Volume: 134, Issue:12

    Topics: Amisulpride; Antipsychotic Agents; Drug Overdose; Female; Follow-Up Studies; Humans; Long QT Syndrom

2010
Amisulpride overdose is frequently associated with QT prolongation and torsades de pointes.
    Journal of clinical psychopharmacology, 2010, Volume: 30, Issue:4

    Topics: Adult; Amisulpride; Antipsychotic Agents; Bradycardia; Cohort Studies; Drug Overdose; Electrocardiog

2010
Amisulpride overdose: suggested management of prolonged QTc.
    Emergency medicine journal : EMJ, 2010, Volume: 27, Issue:7

    Topics: Adult; Amisulpride; Antipsychotic Agents; Calcium; Drug Overdose; Humans; Hypocalcemia; Infusions, I

2010
Prediction of torsade de pointes from the QT interval: analysis of a case series of amisulpride overdoses.
    Clinical pharmacology and therapeutics, 2011, Volume: 90, Issue:2

    Topics: Adolescent; Adult; Amisulpride; Antipsychotic Agents; Dose-Response Relationship, Drug; Drug Overdos

2011
[Sulpiride poisoning--case report confirmed with the quantitative determination of the xenobiotic serum level].
    Przeglad lekarski, 2011, Volume: 68, Issue:8

    Topics: Adolescent; Drug Overdose; Electrocardiography; Female; Humans; Hypotension, Orthostatic; Sulpiride;

2011
Amisulpride deliberate self-poisoning causing severe cardiac toxicity including QT prolongation and torsades de pointes.
    The Medical journal of Australia, 2006, Apr-03, Volume: 184, Issue:7

    Topics: Adult; Amisulpride; Antipsychotic Agents; Arrhythmias, Cardiac; Drug Overdose; Electrocardiography;

2006
Hemoperfusion in the treatment of acute clozapine intoxication in China.
    Journal of clinical psychopharmacology, 2007, Volume: 27, Issue:6

    Topics: Acute Disease; Adult; Alprazolam; Antipsychotic Agents; China; Clonazepam; Clozapine; Depressive Dis

2007
Physostigmine as treatment for severe CNS anticholinergic toxicity.
    Emergency medicine journal : EMJ, 2001, Volume: 18, Issue:5

    Topics: Amisulpride; Antipsychotic Agents; Cholinesterase Inhibitors; Drug Overdose; Humans; Male; Muscarini

2001