Page last updated: 2024-11-04

sulpiride and Colitis

sulpiride has been researched along with Colitis in 2 studies

Sulpiride: A dopamine D2-receptor antagonist. It has been used therapeutically as an antidepressant, antipsychotic, and as a digestive aid. (From Merck Index, 11th ed)
sulpiride : A member of the class of benzamides obtained from formal condensation between the carboxy group of 2-methoxy-5-sulfamoylbenzoic acid and the primary amino group of (1-ethylpyrrolidin-2-yl)methylamine.

Colitis: Inflammation of the COLON section of the large intestine (INTESTINE, LARGE), usually with symptoms such as DIARRHEA (often with blood and mucus), ABDOMINAL PAIN, and FEVER.

Research Excerpts

ExcerptRelevanceReference
"To test whether sulpiride (SP), an anti-psychotic and prokinetic drug, shows beneficial effects on experimental murine colitis, a colon-targeted prodrug of SP, 5-(aminoethanoylsulfamoyl)-N-[(1-ethylpyrrolidin-2-yl)methyl]-2-methoxybenzamide (glycylsulpiride (GSP)), was synthesized and its colonic delivery and therapeutic activity against 2,4-dinitrobenzenesulfonic acid (DNBS)-induced rat colitis were assessed."3.91Therapeutic switching of sulpiride, an anti-psychotic and prokinetic drug, to an anti-colitic drug using colon-specific drug delivery. ( Jeong, S; Jung, Y; Kim, D; Kim, W; Yoo, JW, 2019)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19901 (50.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kim, D2
Kim, W1
Jeong, S1
Yoo, JW1
Jung, Y1
Morini, A1
Mauceri, P1
Pallotta, P1
Pelliccia, G1

Other Studies

2 other studies available for sulpiride and Colitis

ArticleYear
Therapeutic switching of sulpiride, an anti-psychotic and prokinetic drug, to an anti-colitic drug using colon-specific drug delivery.
    Drug delivery and translational research, 2019, Volume: 9, Issue:1

    Topics: Animals; Benzamides; Colitis; Colon; Dinitrofluorobenzene; Disease Models, Animal; Dose-Response Rel

2019
[Irritable colon and psychosomatic disease].
    Minerva medica, 1984, Aug-25, Volume: 75, Issue:32-33

    Topics: Antidepressive Agents, Tricyclic; Benzodiazepines; Colitis; Colonic Diseases, Functional; Dyspepsia;

1984