sulpiride has been researched along with Colitis in 2 studies
Sulpiride: A dopamine D2-receptor antagonist. It has been used therapeutically as an antidepressant, antipsychotic, and as a digestive aid. (From Merck Index, 11th ed)
sulpiride : A member of the class of benzamides obtained from formal condensation between the carboxy group of 2-methoxy-5-sulfamoylbenzoic acid and the primary amino group of (1-ethylpyrrolidin-2-yl)methylamine.
Colitis: Inflammation of the COLON section of the large intestine (INTESTINE, LARGE), usually with symptoms such as DIARRHEA (often with blood and mucus), ABDOMINAL PAIN, and FEVER.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To test whether sulpiride (SP), an anti-psychotic and prokinetic drug, shows beneficial effects on experimental murine colitis, a colon-targeted prodrug of SP, 5-(aminoethanoylsulfamoyl)-N-[(1-ethylpyrrolidin-2-yl)methyl]-2-methoxybenzamide (glycylsulpiride (GSP)), was synthesized and its colonic delivery and therapeutic activity against 2,4-dinitrobenzenesulfonic acid (DNBS)-induced rat colitis were assessed." | 3.91 | Therapeutic switching of sulpiride, an anti-psychotic and prokinetic drug, to an anti-colitic drug using colon-specific drug delivery. ( Jeong, S; Jung, Y; Kim, D; Kim, W; Yoo, JW, 2019) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (50.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kim, D | 2 |
| Kim, W | 1 |
| Jeong, S | 1 |
| Yoo, JW | 1 |
| Jung, Y | 1 |
| Morini, A | 1 |
| Mauceri, P | 1 |
| Pallotta, P | 1 |
| Pelliccia, G | 1 |
2 other studies available for sulpiride and Colitis
| Article | Year |
|---|---|
Therapeutic switching of sulpiride, an anti-psychotic and prokinetic drug, to an anti-colitic drug using colon-specific drug delivery.
Topics: Animals; Benzamides; Colitis; Colon; Dinitrofluorobenzene; Disease Models, Animal; Dose-Response Rel | 2019 |
[Irritable colon and psychosomatic disease].
Topics: Antidepressive Agents, Tricyclic; Benzodiazepines; Colitis; Colonic Diseases, Functional; Dyspepsia; | 1984 |