Page last updated: 2024-11-04

sulpiride and Cocaine Abuse

sulpiride has been researched along with Cocaine Abuse in 3 studies

Sulpiride: A dopamine D2-receptor antagonist. It has been used therapeutically as an antidepressant, antipsychotic, and as a digestive aid. (From Merck Index, 11th ed)
sulpiride : A member of the class of benzamides obtained from formal condensation between the carboxy group of 2-methoxy-5-sulfamoylbenzoic acid and the primary amino group of (1-ethylpyrrolidin-2-yl)methylamine.

Research Excerpts

ExcerptRelevanceReference
"To measure behavioral and brain functional markers of drug-related attentional bias in stimulant-dependent individuals studied repeatedly after short-term dosing with dopamine D(2)/D(3) receptor antagonist and agonist challenges."1.36Influence of compulsivity of drug abuse on dopaminergic modulation of attentional bias in stimulant dependence. ( Abbott, S; Barnes, A; Bullmore, ET; Craig, KJ; Ersche, KD; Merlo-Pich, EV; Müller, U; Ooi, C; Robbins, TW; Sahakian, BJ; Shabbir, SS; Suckling, J, 2010)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (33.33)29.6817
2010's2 (66.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ersche, KD2
Bullmore, ET2
Craig, KJ2
Shabbir, SS2
Abbott, S2
Müller, U2
Ooi, C2
Suckling, J2
Barnes, A1
Sahakian, BJ2
Merlo-Pich, EV2
Robbins, TW2
Roiser, JP1
Clark, L1
Fineberg, NA1
Zhou, Y1
Spangler, R1
Ho, A1
Jeanne Kreek, M1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Dopamine D2/3- and μ-opioid Receptor Antagonists Reduce Cue-induced Reward Responding and Reward Impulsivity in Healthy Volunteers[NCT02557984]121 participants (Actual)Interventional2014-02-28Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

1 trial available for sulpiride and Cocaine Abuse

ArticleYear
Response perseveration in stimulant dependence is associated with striatal dysfunction and can be ameliorated by a D(2/3) receptor agonist.
    Biological psychiatry, 2011, Oct-15, Volume: 70, Issue:8

    Topics: Adult; Amisulpride; Amphetamine-Related Disorders; Benzothiazoles; Brain Mapping; Cocaine-Related Di

2011

Other Studies

2 other studies available for sulpiride and Cocaine Abuse

ArticleYear
Influence of compulsivity of drug abuse on dopaminergic modulation of attentional bias in stimulant dependence.
    Archives of general psychiatry, 2010, Volume: 67, Issue:6

    Topics: Adult; Amisulpride; Amphetamine-Related Disorders; Attention; Benzothiazoles; Bias; Cerebellar Corte

2010
Hypothalamic CRH mRNA levels are differentially modulated by repeated 'binge' cocaine with or without D(1) dopamine receptor blockade.
    Brain research. Molecular brain research, 2001, Oct-19, Volume: 94, Issue:1-2

    Topics: Amygdala; Animals; Benzazepines; Cocaine; Cocaine-Related Disorders; Corticotropin-Releasing Hormone

2001