Page last updated: 2024-11-04

sulpiride and Chronic Disease

sulpiride has been researched along with Chronic Disease in 33 studies

Sulpiride: A dopamine D2-receptor antagonist. It has been used therapeutically as an antidepressant, antipsychotic, and as a digestive aid. (From Merck Index, 11th ed)
sulpiride : A member of the class of benzamides obtained from formal condensation between the carboxy group of 2-methoxy-5-sulfamoylbenzoic acid and the primary amino group of (1-ethylpyrrolidin-2-yl)methylamine.

Chronic Disease: Diseases which have one or more of the following characteristics: they are permanent, leave residual disability, are caused by nonreversible pathological alteration, require special training of the patient for rehabilitation, or may be expected to require a long period of supervision, observation, or care (Dictionary of Health Services Management, 2d ed). For epidemiological studies chronic disease often includes HEART DISEASES; STROKE; CANCER; and diabetes (DIABETES MELLITUS, TYPE 2).

Research Excerpts

ExcerptRelevanceReference
"This multicenter, double-blind, randomized study evaluated the efficacy, safety and functional effects of two atypical antipsychotics, amisulpride and risperidone, in patients with chronic schizophrenia (DSM IV) with a recent worsening of symptoms."9.10Amisulpride vs. risperidone in chronic schizophrenia: results of a 6-month double-blind study. ( Fleurot, O; Lecrubier, Y; Peuskens, J; Rein, W; Sechter, D, 2002)
"In lumbar cerebrospinal fluid (CSF) obtained from patients with chronic tension-type headache (CTH), the concentrations of beta-endorphin, met-enkephalin, dynorphin, cholecystokinin (CCK), calcitonin gene-related peptide (CGRP), and somatostatin were measured before and after 8 weeks of treatment with sulpiride or paroxetine."9.07Effect of sulpiride or paroxetine on cerebrospinal fluid neuropeptide concentrations in patients with chronic tension-type headache. ( Bach, FW; Ekman, R; Langemark, M; Olesen, J; Rehfeld, JF; Schifter, S, 1994)
" A serotonin re-uptake inhibitor, paroxetine (20-30 mg daily), and a dopamine antagonist, sulpiride (200-400 mg daily) were compared in a randomized, double-blind, response-conditional cross-over pilot study in 50 non-depressed patients with chronic tension-type headache."9.07Sulpiride and paroxetine in the treatment of chronic tension-type headache. An explanatory double-blind trial. ( Langemark, M; Olesen, J, 1994)
"Seventeen patients with acute schizophrenia and 30 with chronic schizophrenia were included in a randomized, double-blind parallel-group trial comparing sulpiride and perphenazine."9.06Sulpiride and perphenazine in schizophrenia. A double-blind clinical trial. ( Gordin, A; Koskinen, T; Lepola, U; Rimón, R; Salo, H, 1989)
" Following this, two dosage regiments, a morning only dose, and the same daily total dose in two equal fractions at 8 a."6.65Sulpiride trial in chronic schizophrenia with comparison of two dosage regimens. ( Bond, HR; Curry, SH; Lewis, DM, 1983)
"Haloperidol (HAL) is a compound that shows a high affinity with these receptors, acting as an antagonist."5.46Haloperidol Decreases Hyperalgesia and Allodynia Induced by Chronic Constriction Injury. ( Espinosa-Juárez, JV; Jaramillo-Morales, OA; López-Muñoz, FJ, 2017)
"Sulpiride is a selective dopamine D2 antagonist."5.35Short-term sulpiride treatment of children and adolescents with Tourette syndrome or chronic tic disorder. ( Chen, HJ; Chiu, NC; Ho, CS; Lue, HC; Shen, EY, 2009)
"This multicenter, double-blind, randomized study evaluated the efficacy, safety and functional effects of two atypical antipsychotics, amisulpride and risperidone, in patients with chronic schizophrenia (DSM IV) with a recent worsening of symptoms."5.10Amisulpride vs. risperidone in chronic schizophrenia: results of a 6-month double-blind study. ( Fleurot, O; Lecrubier, Y; Peuskens, J; Rein, W; Sechter, D, 2002)
" In this long-term, open, randomised, multicentre trial, patients with chronic or subchronic schizophrenia received amisulpride (n =370) or haloperidol (n = 118) for 12 months."5.09Long-term safety and efficacy of amisulpride in subchronic or chronic schizophrenia. Amisulpride Study Group. ( Colonna, L; Dondey-Nouvel, L; Rein, W; Saleem, P, 2000)
"In lumbar cerebrospinal fluid (CSF) obtained from patients with chronic tension-type headache (CTH), the concentrations of beta-endorphin, met-enkephalin, dynorphin, cholecystokinin (CCK), calcitonin gene-related peptide (CGRP), and somatostatin were measured before and after 8 weeks of treatment with sulpiride or paroxetine."5.07Effect of sulpiride or paroxetine on cerebrospinal fluid neuropeptide concentrations in patients with chronic tension-type headache. ( Bach, FW; Ekman, R; Langemark, M; Olesen, J; Rehfeld, JF; Schifter, S, 1994)
" A serotonin re-uptake inhibitor, paroxetine (20-30 mg daily), and a dopamine antagonist, sulpiride (200-400 mg daily) were compared in a randomized, double-blind, response-conditional cross-over pilot study in 50 non-depressed patients with chronic tension-type headache."5.07Sulpiride and paroxetine in the treatment of chronic tension-type headache. An explanatory double-blind trial. ( Langemark, M; Olesen, J, 1994)
"Seventeen patients with acute schizophrenia and 30 with chronic schizophrenia were included in a randomized, double-blind parallel-group trial comparing sulpiride and perphenazine."5.06Sulpiride and perphenazine in schizophrenia. A double-blind clinical trial. ( Gordin, A; Koskinen, T; Lepola, U; Rimón, R; Salo, H, 1989)
" To enhance PRL release, we induced hyperprolactinemia by administering chronic injections of sulpiride (40 mg."3.71Effects of hyperprolactinemia on rat prostate growth: evidence of androgeno-dependence. ( Ahidouch, A; Authie, D; Beauvillain, JC; Carpentier, F; Cousse, H; Croix, D; Dewailly, E; Dupouy, JP; Fournier, S; Le Bourhis, X; Legrand, G; Prevarskaya, N; Raynaud, JP; Slomianny, C; Van Coppenolle, F, 2001)
" The drug had only a limited effect in reducing negative symptoms, which were relatively stable, enduring phenomena in this sample, despite dosage reduction."2.68One-year, low-dose neuroleptic study of in-patients with chronic schizophrenia characterised by persistent negative symptoms. Amisulpride v. haloperidol. ( Alberts, JL; Barnes, TR; Curson, DA; Pantelis, C; Speller, JC, 1997)
"22 patients (8 manic-depressive psychoses and 14 schizophrenias) were given sultopride as the sole therapy, in a daily dose of 4 vials."2.65[Longterm psychosis and sultopride]. ( Morel, D, 1983)
" Following this, two dosage regiments, a morning only dose, and the same daily total dose in two equal fractions at 8 a."2.65Sulpiride trial in chronic schizophrenia with comparison of two dosage regimens. ( Bond, HR; Curry, SH; Lewis, DM, 1983)
"Treatment with sulpiride was associated with a significant rise in plasma prolactin level, but paradoxically these patients had significantly reduced extrapyramidal symptoms."2.65A clinical and pharmacodynamic evaluation of sulpiride. ( Bailey, J; Bishop, M; Coppen, A; Rao, VA, 1981)
" Safety was monitored by open adverse event reporting, the Simpson-Angus Scale, the Barnes Akathisia Scale and the Abnormal Involuntary Movement scale."2.41Safety profile of amisulpride in short- and long-term use. ( Coulouvrat, C; Dondey-Nouvel, L; Rein, W, 2000)
" In patients with acute exacerbations of schizophrenia, the recommended dosage of amisulpride is 400 to 800 mg/day, although dosages < or =1200 mg/day may be administered."2.41Amisulpride: a review of its use in the management of schizophrenia. ( Curran, MP; Perry, CM, 2001)
"Haloperidol (HAL) is a compound that shows a high affinity with these receptors, acting as an antagonist."1.46Haloperidol Decreases Hyperalgesia and Allodynia Induced by Chronic Constriction Injury. ( Espinosa-Juárez, JV; Jaramillo-Morales, OA; López-Muñoz, FJ, 2017)
"Sulpiride is a selective dopamine D2 antagonist."1.35Short-term sulpiride treatment of children and adolescents with Tourette syndrome or chronic tic disorder. ( Chen, HJ; Chiu, NC; Ho, CS; Lue, HC; Shen, EY, 2009)

Research

Studies (33)

TimeframeStudies, this research(%)All Research%
pre-199012 (36.36)18.7374
1990's6 (18.18)18.2507
2000's14 (42.42)29.6817
2010's1 (3.03)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Espinosa-Juárez, JV1
Jaramillo-Morales, OA1
López-Muñoz, FJ1
Mendhekar, DN1
Terai, H1
Shimahara, M1
Ho, CS1
Chen, HJ1
Chiu, NC1
Shen, EY1
Lue, HC1
del Rosario, CN1
Pacchioni, AM1
Cancela, LM1
Sechter, D1
Peuskens, J1
Fleurot, O1
Rein, W3
Lecrubier, Y2
French, K1
Eastwood, D1
Kotler, M1
Strous, RD1
Reznik, I1
Shwartz, S1
Weizman, A1
Spivak, B1
Quintin, P1
Bouhassira, M1
Perrin, E1
Lancrenon, S1
Morel, D1
Lewis, DM1
Bond, HR1
Curry, SH1
Miyachi, Y1
Mizuchi, A1
Hamano, H1
Sarai, K1
Rao, VA1
Bailey, J1
Bishop, M1
Coppen, A1
Edwards, JG1
Alexander, JR1
Alexander, MS1
Gordon, A1
Zutchi, T1
Maier, W1
Benkert, O1
Bach, FW1
Langemark, M2
Ekman, R1
Rehfeld, JF1
Schifter, S1
Olesen, J2
Freeman, HL1
Speller, JC1
Barnes, TR1
Curson, DA1
Pantelis, C1
Alberts, JL1
Möller, HJ2
Coulouvrat, C1
Dondey-Nouvel, L2
Colonna, L1
Saleem, P1
Van Coppenolle, F1
Slomianny, C1
Carpentier, F1
Le Bourhis, X1
Ahidouch, A1
Croix, D1
Legrand, G1
Dewailly, E1
Fournier, S1
Cousse, H1
Authie, D1
Raynaud, JP1
Beauvillain, JC1
Dupouy, JP1
Prevarskaya, N1
Curran, MP1
Perry, CM1
Mielke, DH1
Gallant, DM1
Roniger, JJ1
Kessler, C1
Eckmann, F1
Lepola, U1
Koskinen, T1
Rimón, R1
Salo, H1
Gordin, A1
Zarebinski, JM1
Meltzer, HY1
Yamagami, S1
Kiriike, N1
Kawaguchi, K1
Masciocchi, A1
Reitano, S1
Vanini, M1
Cicchetti, V1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Behavioral Therapy for Children and Adolescents With Tourette Syndrome: A Randomized Controlled Trial in Taiwan[NCT03621059]46 participants (Actual)Interventional2015-01-01Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

4 reviews available for sulpiride and Chronic Disease

ArticleYear
Amisulpride compared with standard neuroleptics in acute exacerbations of schizophrenia: three efficacy studies.
    International clinical psychopharmacology, 1997, Volume: 12 Suppl 2

    Topics: Adult; Amisulpride; Antipsychotic Agents; Chronic Disease; Dose-Response Relationship, Drug; Double-

1997
Amisulpride: a review of its efficacy in schizophrenia.
    Acta psychiatrica Scandinavica. Supplementum, 2000, Volume: 400

    Topics: Acute Disease; Amisulpride; Antipsychotic Agents; Brief Psychiatric Rating Scale; Chronic Disease; C

2000
Safety profile of amisulpride in short- and long-term use.
    Acta psychiatrica Scandinavica. Supplementum, 2000, Volume: 400

    Topics: Amisulpride; Antipsychotic Agents; Chronic Disease; Clinical Trials as Topic; Drug Administration Sc

2000
Amisulpride: a review of its use in the management of schizophrenia.
    Drugs, 2001, Volume: 61, Issue:14

    Topics: Acute Disease; Administration, Oral; Adsorption; Amisulpride; Antipsychotic Agents; Chronic Disease;

2001

Trials

16 trials available for sulpiride and Chronic Disease

ArticleYear
Amisulpride vs. risperidone in chronic schizophrenia: results of a 6-month double-blind study.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2002, Volume: 27, Issue:6

    Topics: Adolescent; Adult; Aged; Amisulpride; Analysis of Variance; Chi-Square Distribution; Chronic Disease

2002
Sulpiride augmentation of olanzapine in the management of treatment-resistant chronic schizophrenia: evidence for improvement of mood symptomatology.
    International clinical psychopharmacology, 2004, Volume: 19, Issue:1

    Topics: Adolescent; Adult; Affect; Antipsychotic Agents; Anxiety; Basal Ganglia Diseases; Benzodiazepines; C

2004
The treatment of negative symptoms and deficit states of chronic schizophrenia: olanzapine compared to amisulpride and placebo in a 6-month double-blind controlled clinical trial.
    Acta psychiatrica Scandinavica, 2006, Volume: 114, Issue:5

    Topics: Adult; Affect; Amisulpride; Antipsychotic Agents; Attention; Basal Ganglia Diseases; Benzodiazepines

2006
[Longterm psychosis and sultopride].
    La semaine des hopitaux : organe fonde par l'Association d'enseignement medical des hopitaux de Paris, 1983, Sep-22, Volume: 59, Issue:33

    Topics: Adult; Amisulpride; Chronic Disease; Clinical Trials as Topic; Female; Humans; Male; Middle Aged; Ps

1983
Sulpiride trial in chronic schizophrenia with comparison of two dosage regimens.
    Psychopharmacology, 1983, Volume: 80, Issue:3

    Topics: Adult; Chronic Disease; Double-Blind Method; Drug Administration Schedule; Female; Humans; Male; Mid

1983
A clinical and pharmacodynamic evaluation of sulpiride.
    Psychopharmacology, 1981, Volume: 73, Issue:1

    Topics: Chronic Disease; Clinical Trials as Topic; Double-Blind Method; Female; Haloperidol; Humans; Middle

1981
Controlled trial of sulpiride in chronic schizophrenic patients.
    The British journal of psychiatry : the journal of mental science, 1980, Volume: 137

    Topics: Adult; Aged; Chronic Disease; Clinical Trials as Topic; Dose-Response Relationship, Drug; Double-Bli

1980
Treatment of chronic depression with sulpiride: evidence of efficacy in placebo-controlled single case studies.
    Psychopharmacology, 1994, Volume: 115, Issue:4

    Topics: Adult; Anxiety; Case-Control Studies; Chronic Disease; Cross-Over Studies; Depressive Disorder; Doub

1994
Effect of sulpiride or paroxetine on cerebrospinal fluid neuropeptide concentrations in patients with chronic tension-type headache.
    Neuropeptides, 1994, Volume: 27, Issue:2

    Topics: Adult; Aged; Basal Metabolism; Calcitonin Gene-Related Peptide; Cholecystokinin; Chronic Disease; Do

1994
Sulpiride and paroxetine in the treatment of chronic tension-type headache. An explanatory double-blind trial.
    Headache, 1994, Volume: 34, Issue:1

    Topics: Adult; Aged; Chronic Disease; Double-Blind Method; Female; Headache; Humans; Male; Middle Aged; Musc

1994
One-year, low-dose neuroleptic study of in-patients with chronic schizophrenia characterised by persistent negative symptoms. Amisulpride v. haloperidol.
    The British journal of psychiatry : the journal of mental science, 1997, Volume: 171

    Topics: Adult; Aged; Amisulpride; Antipsychotic Agents; Chronic Disease; Double-Blind Method; Female; Humans

1997
Long-term safety and efficacy of amisulpride in subchronic or chronic schizophrenia. Amisulpride Study Group.
    International clinical psychopharmacology, 2000, Volume: 15, Issue:1

    Topics: Adolescent; Adult; Aged; Amisulpride; Antipsychotic Agents; Chronic Disease; Dyskinesia, Drug-Induce

2000
Amisulpride: efficacy in the management of chronic patients with predominant negative symptoms of schizophrenia.
    European archives of psychiatry and clinical neuroscience, 2001, Volume: 251, Issue:5

    Topics: Adolescent; Adult; Aged; Amisulpride; Antipsychotic Agents; Basal Ganglia Diseases; Chronic Disease;

2001
[Clinical studies with sulpiride in schizophrenics hospitalized for many years].
    Agressologie: revue internationale de physio-biologie et de pharmacologie appliquees aux effets de l'agression, 1978, Volume: 19, Issue:C

    Topics: Adult; Aged; Chronic Disease; Clinical Trials as Topic; Female; Humans; Male; Middle Aged; Schizophr

1978
Sulpiride and perphenazine in schizophrenia. A double-blind clinical trial.
    Acta psychiatrica Scandinavica, 1989, Volume: 80, Issue:1

    Topics: Acute Disease; Adolescent; Adult; Aged; Chronic Disease; Clinical Trials as Topic; Double-Blind Meth

1989
A single-blind study of clocapramine and sulpiride in hospitalized chronic schizophrenic patients.
    Drugs under experimental and clinical research, 1988, Volume: 14, Issue:11

    Topics: Adult; Chronic Disease; Dibenzazepines; Female; Humans; Male; Middle Aged; Psychiatric Status Rating

1988

Other Studies

13 other studies available for sulpiride and Chronic Disease

ArticleYear
Haloperidol Decreases Hyperalgesia and Allodynia Induced by Chronic Constriction Injury.
    Basic & clinical pharmacology & toxicology, 2017, Volume: 121, Issue:6

    Topics: Amines; Analgesics; Animals; Antipsychotic Agents; Chronic Disease; Constriction, Pathologic; Cycloh

2017
Hyperpigmentation with amisulpride.
    The Australian and New Zealand journal of psychiatry, 2009, Volume: 43, Issue:1

    Topics: Adult; Amisulpride; Antipsychotic Agents; Chronic Disease; Drug Therapy, Combination; Female; Fluvox

2009
Chronic tongue ulceration resolved by sulpiride: a report of two cases.
    Clinical and experimental dermatology, 2009, Volume: 34, Issue:5

    Topics: Aged, 80 and over; Candidiasis, Oral; Chronic Disease; Dopamine Antagonists; Female; Humans; Oral Ul

2009
Short-term sulpiride treatment of children and adolescents with Tourette syndrome or chronic tic disorder.
    Journal of the Formosan Medical Association = Taiwan yi zhi, 2009, Volume: 108, Issue:10

    Topics: Adolescent; Child; Child, Preschool; Chronic Disease; Dopamine Antagonists; Dose-Response Relationsh

2009
Influence of acute or repeated restraint stress on morphine-induced locomotion: involvement of dopamine, opioid and glutamate receptors.
    Behavioural brain research, 2002, Aug-21, Volume: 134, Issue:1-2

    Topics: Acute Disease; Animals; Benzazepines; Chronic Disease; Dizocilpine Maleate; Dopamine Antagonists; Do

2002
Response of catatonic schizophrenia to amisulpride: a case report.
    Canadian journal of psychiatry. Revue canadienne de psychiatrie, 2003, Volume: 48, Issue:8

    Topics: Adult; Amisulpride; Antipsychotic Agents; Chronic Disease; Humans; Male; Schizophrenia, Catatonic; S

2003
Effects of chronic sultopride treatment on endocrine systems in psychotic women.
    Psychopharmacology, 1984, Volume: 82, Issue:4

    Topics: Adult; Amisulpride; Chronic Disease; Estradiol; Female; Follicle Stimulating Hormone; Growth Hormone

1984
[Amisulpride--a neuroleptic agent for all phases of schizophrenia].
    Der Nervenarzt, 1999, Volume: 70, Issue:3 Suppl Am

    Topics: Amisulpride; Antipsychotic Agents; Chronic Disease; Humans; Hyperkinesis; Hypertension; Risk Factors

1999
Effects of hyperprolactinemia on rat prostate growth: evidence of androgeno-dependence.
    American journal of physiology. Endocrinology and metabolism, 2001, Volume: 280, Issue:1

    Topics: Animals; Apoptosis; Chronic Disease; Dihydrotestosterone; Dopamine Antagonists; Gonadal Steroid Horm

2001
Sulpiride: evaluation of antipsychotic activity in chronic schizophrenic patients.
    Psychopharmacology bulletin, 1977, Volume: 13, Issue:3

    Topics: Antipsychotic Agents; Chronic Disease; Humans; Schizophrenia; Sulpiride

1977
Sulpiride in the treatment of chronic schizophrenia.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1989, Nov-04, Volume: 76, Issue:9

    Topics: Chlorpromazine; Chronic Disease; Drug Therapy, Combination; Humans; Male; Schizophrenia; Sulpiride

1989
Effect of neuroleptics on the schizophrenic syndrome.
    Psychopharmacology series, 1987, Volume: 3

    Topics: Adult; Antipsychotic Agents; Chlorpromazine; Chronic Disease; Clozapine; Female; Humans; Male; Schiz

1987
[Preliminary results of a controlled trial with sulpiride versus chlorimipramine in chronic schizophrenic patients with marked ideo-emotional poverty (author's transl)].
    Rivista di patologia nervosa e mentale, 1974, Volume: 95, Issue:1

    Topics: Affect; Anxiety; Chronic Disease; Clomipramine; Depression; Dibenzazepines; Humans; Mental Processes

1974
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