Page last updated: 2024-11-04

sulpiride and Bipolar Disorder

sulpiride has been researched along with Bipolar Disorder in 30 studies

Sulpiride: A dopamine D2-receptor antagonist. It has been used therapeutically as an antidepressant, antipsychotic, and as a digestive aid. (From Merck Index, 11th ed)
sulpiride : A member of the class of benzamides obtained from formal condensation between the carboxy group of 2-methoxy-5-sulfamoylbenzoic acid and the primary amino group of (1-ethylpyrrolidin-2-yl)methylamine.

Bipolar Disorder: A major affective disorder marked by severe mood swings (manic or major depressive episodes) and a tendency to remission and recurrence.

Research Excerpts

ExcerptRelevanceReference
"Randomised trials comparing haloperidol with placebo or other active treatment in the treatment of acute manic or mixed episodes in patients with bipolar disorder or schizoaffective disorder."4.83Haloperidol alone or in combination for acute mania. ( Cipriani, A; Geddes, JR; Rendell, JM, 2006)
"A 19-year-old man with schizophrenia and underlying cerebral disease developed rapid-onset mania after risperidone was replaced with amisulpride."3.80Amisulpride-associated mania in a young adult with schizophrenia and cerebral disease. ( Chen, CY; Chen, TY; Chuang, WC; Kuo, SC; Yeh, YW, 2014)
"Clozapine had a significantly lower discontinuation rate in individuals with schizophrenia, compared to the other 4 SGAs."3.74Comparing the use and discontinuation of antipsychotics in clinical practice: an observational study. ( Lawrie, SM; Shajahan, P; Taylor, M, 2008)
"Toxic epidermal necrolysis (Lyell syndrome) developed in a 43-year woman treated with carbamazepine, perazine, and sulpiride for recurrent manic bipolar disorder."3.68[Electroconvulsive therapy in treatment of acute life threatening catatonia in toxic epidermal necrolysis (Lyell syndrome)]. ( Beckmann, H; Kornhuber, J; Weller, M, 1992)
"This does not extend to bipolar depression, however, good data is now emerging for some agents and will need to be considered for each individual agent as it accumulates."2.43A typical mood stabilizers: a "typical role for atypical antipsychotics. ( Berk, M; Bourin, M; Dodd, S; Ivanovski, B; Lagopoulos, J; Malhi, GS; Mitchell, PB, 2005)
"Risperidone monotherapy treatment was associated with hyperprolactinaemia in 69% of patients ( n = 35) and in 100% of female patients (n = 16) and amisulpride monotherapy in 100% (n = 7)."1.34Prevalence of hyperprolactinaemia in a naturalistic cohort of schizophrenia and bipolar outpatients during treatment with typical and atypical antipsychotics. ( Bushe, C; Shaw, M, 2007)

Research

Studies (30)

TimeframeStudies, this research(%)All Research%
pre-19908 (26.67)18.7374
1990's3 (10.00)18.2507
2000's11 (36.67)29.6817
2010's8 (26.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Wang, EH1
Yang, AC1
Hou, YC1
Lai, CH1
Chuang, WC1
Chen, CY2
Kuo, SC1
Chen, TY2
Yeh, YW1
Hong, CC1
Chen, CK1
Yeh, TC1
Chu, CS1
Mendhekar, DN1
Gupta, N1
Bakhla, AK1
Goyal, N2
Nizamie, SH1
Yasugi, S1
Garg, V1
Been, G1
Magoulas, P1
Teoh, S1
Ilett, KF1
Hackett, LP1
Kohan, R1
Teng, PR1
Shen, TY1
Lai, TJ1
Garg, S1
Sinha, VK1
Murphy, BP1
Vieta, E1
Ros, S1
Goikolea, JM1
Benabarre, A1
Popova, E1
Comes, M1
Capapey, J1
Sánchez-Moreno, J1
Malhi, GS1
Berk, M1
Bourin, M1
Ivanovski, B1
Dodd, S1
Lagopoulos, J1
Mitchell, PB1
Cipriani, A1
Rendell, JM1
Geddes, JR1
Huang, BH1
Hsia, CP1
Bushe, C1
Shaw, M1
Bret, MC1
Bret, P1
Pariente, A1
Fourier-Réglat, A1
Abay, E1
Kose, R1
Taylor, M1
Shajahan, P1
Lawrie, SM1
Planche, R1
Lang, F1
Berger, M1
Tamet, JY1
Bocchetta, A1
Bernardi, F1
Burrai, C1
Pedditzi, M1
Del Zompo, M2
Ebert, D1
Feistel, H1
Barocka, A1
Kaschka, W1
Mokrusch, T1
Corsini, GU1
Manconi, S1
Cianchetti, C1
Mangoni, A1
Gessa, GL1
Richou, H1
Hug, R1
Brion, S1
Chevalier, JF1
Guerin, R1
Ginestet, D1
Maurel, H1
Pujol, B1
Weller, M1
Kornhuber, J1
Beckmann, H1
Shima, S1
Bruscky, SB1
Caldeira, MV1
Bueno, JR1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Sulpiride Versus Placebo for Reducting Hot Flushes During Climacteric: a Double-blind Randomized Clinical Trial[NCT02749747]Phase 328 participants (Actual)Interventional2014-06-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

2 reviews available for sulpiride and Bipolar Disorder

ArticleYear
A typical mood stabilizers: a "typical role for atypical antipsychotics.
    Acta psychiatrica Scandinavica. Supplementum, 2005, Issue:426

    Topics: Affect; Amisulpride; Antipsychotic Agents; Aripiprazole; Benzodiazepines; Bipolar Disorder; Clozapin

2005
Haloperidol alone or in combination for acute mania.
    The Cochrane database of systematic reviews, 2006, Jul-19, Issue:3

    Topics: Amisulpride; Antipsychotic Agents; Aripiprazole; Benzodiazepines; Bipolar Disorder; Carbamazepine; D

2006

Trials

3 trials available for sulpiride and Bipolar Disorder

ArticleYear
An open-label study of amisulpride in the treatment of mania.
    The Journal of clinical psychiatry, 2005, Volume: 66, Issue:5

    Topics: Adult; Amisulpride; Antipsychotic Agents; Bipolar Disorder; Drug Administration Schedule; Drug Thera

2005
A double-blind study of L-sulpiride versus amitriptyline in lithium-maintained bipolar depressives.
    Acta psychiatrica Scandinavica, 1993, Volume: 88, Issue:6

    Topics: Ambulatory Care; Amitriptyline; Bipolar Disorder; Constipation; Double-Blind Method; Drug Administra

1993
[Situation of sultopride among present-day neuroleptics].
    L'Encephale, 1975, Volume: 1, Issue:1

    Topics: Anxiety; Asthenia; Basal Ganglia Diseases; Benzamides; Bipolar Disorder; Clinical Trials as Topic; D

1975

Other Studies

25 other studies available for sulpiride and Bipolar Disorder

ArticleYear
Reversible skin rash in a bipolar disorder patient on first use of lithium.
    Psychiatry and clinical neurosciences, 2013, Volume: 67, Issue:5

    Topics: Adult; Antimanic Agents; Antipsychotic Agents; Bipolar Disorder; Drug Eruptions; Exanthema; Female;

2013
The effectiveness of high-dosage amisulpride combined with moderate-dosage sodium valproate treatment for an overweight patient with psychotic bipolar disorder.
    The Journal of neuropsychiatry and clinical neurosciences, 2014, Apr-01, Volume: 26, Issue:2

    Topics: Amisulpride; Antimanic Agents; Antipsychotic Agents; Bipolar Disorder; Drug Therapy, Combination; Fe

2014
Amisulpride-associated mania in a young adult with schizophrenia and cerebral disease.
    American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 2014, Dec-01, Volume: 71, Issue:23

    Topics: Amisulpride; Antipsychotic Agents; Bipolar Disorder; Cerebral Palsy; Drug Administration Schedule; H

2014
Amisulpride monotherapy may be a choice of maintenance treatment for patients with both bipolar I disorder and metabolic syndrome.
    The Australian and New Zealand journal of psychiatry, 2015, Volume: 49, Issue:8

    Topics: Amisulpride; Antipsychotic Agents; Bipolar Disorder; Humans; Male; Metabolic Syndrome; Sulpiride; Yo

2015
Combination therapy of levosulpiride and lamotrigine associated with tardive dyskinesia.
    The Australian and New Zealand journal of psychiatry, 2009, Volume: 43, Issue:2

    Topics: Adult; Antimanic Agents; Bipolar Disorder; Diagnostic and Statistical Manual of Mental Disorders; Dr

2009
Amisulpride-induced mania with interictal psychosis.
    Progress in neuro-psychopharmacology & biological psychiatry, 2009, Nov-13, Volume: 33, Issue:8

    Topics: Adolescent; Amisulpride; Antipsychotic Agents; Bipolar Disorder; Humans; Male; Psychotic Disorders;

2009
Neuroleptic malignant syndrome.
    The Australian and New Zealand journal of psychiatry, 2010, Volume: 44, Issue:6

    Topics: Adult; Amisulpride; Antimanic Agents; Antipsychotic Agents; Bipolar Disorder; Dose-Response Relation

2010
Estimation of rac-amisulpride transfer into milk and of infant dose via milk during its use in a lactating woman with bipolar disorder and schizophrenia.
    Breastfeeding medicine : the official journal of the Academy of Breastfeeding Medicine, 2011, Volume: 6, Issue:2

    Topics: Adult; Amisulpride; Antipsychotic Agents; Bipolar Disorder; Breast Feeding; Child Development; Chrom

2011
Sulpiride-associated torsade de pointes in a woman with bipolar disorder.
    Psychiatry and clinical neurosciences, 2012, Volume: 66, Issue:3

    Topics: Antimanic Agents; Antipsychotic Agents; Bipolar Disorder; Drug Therapy, Combination; Electrocardiogr

2012
Levosulpiride-induced rabbit syndrome.
    The Australian and New Zealand journal of psychiatry, 2013, Volume: 47, Issue:3

    Topics: Antipsychotic Agents; Bipolar Disorder; Dyskinesia, Drug-Induced; Female; Humans; Sulpiride; Young A

2013
Amisulpride-induced mania in a patient with schizophrenia.
    The British journal of psychiatry : the journal of mental science, 2003, Volume: 183

    Topics: Adolescent; Amisulpride; Antipsychotic Agents; Bipolar Disorder; Female; Humans; Schizophrenia; Sulp

2003
Sulpiride induced torsade de pointes.
    International journal of cardiology, 2007, Jun-12, Volume: 118, Issue:3

    Topics: Aged; Antipsychotic Agents; Bipolar Disorder; Coronary Angiography; Dose-Response Relationship, Drug

2007
Prevalence of hyperprolactinaemia in a naturalistic cohort of schizophrenia and bipolar outpatients during treatment with typical and atypical antipsychotics.
    Journal of psychopharmacology (Oxford, England), 2007, Volume: 21, Issue:7

    Topics: Adult; Amisulpride; Antipsychotic Agents; Bipolar Disorder; Cohort Studies; Cross-Sectional Studies;

2007
The use of atypical antipsychotics in French psychiatric hospitals.
    Pharmacy world & science : PWS, 2007, Volume: 29, Issue:5

    Topics: Adult; Age Factors; Amisulpride; Antimanic Agents; Antiparkinson Agents; Antipsychotic Agents; Benzo

2007
Amisulpride-induced neuroleptic malignant syndrome.
    The Journal of neuropsychiatry and clinical neurosciences, 2007,Fall, Volume: 19, Issue:4

    Topics: Aged; Amisulpride; Antipsychotic Agents; Bipolar Disorder; Creatine Kinase; Humans; Male; Neurolepti

2007
Comparing the use and discontinuation of antipsychotics in clinical practice: an observational study.
    The Journal of clinical psychiatry, 2008, Volume: 69, Issue:2

    Topics: Adult; Aged; Amisulpride; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Clozapine; Dibenz

2008
[Long-term use of 200 mg Dogmatil. Apropos of 13 cases].
    La semaine des hopitaux : organe fonde par l'Association d'enseignement medical des hopitaux de Paris, 1984, Mar-22, Volume: 60, Issue:13

    Topics: Adult; Amitriptyline; Antipsychotic Agents; Bipolar Disorder; Borderline Personality Disorder; Drug

1984
[Sultopride treatment of a chronic psychotic child with predominantly maniacal manifestations].
    La semaine des hopitaux : organe fonde par l'Association d'enseignement medical des hopitaux de Paris, 1982, Dec-02, Volume: 58, Issue:44

    Topics: Affective Disorders, Psychotic; Amisulpride; Bipolar Disorder; Child; Female; Humans; Psychotropic D

1982
A test-retest study of cerebral blood flow during somatosensory stimulation in depressed patients with schizophrenia and major depression.
    European archives of psychiatry and clinical neuroscience, 1993, Volume: 242, Issue:4

    Topics: Adult; Amitriptyline; Bipolar Disorder; Brain; Brain Mapping; Depressive Disorder; Dominance, Cerebr

1993
Sedative, hypnotic, and antipsychotic effects of low doses of apomorphine in man.
    Advances in biochemical psychopharmacology, 1977, Volume: 16

    Topics: Adolescent; Adult; Antipsychotic Agents; Apomorphine; Bipolar Disorder; Drug Interactions; Female; H

1977
[Sultopride in a day hospital].
    Lille medical : journal de la Faculte de medecine et de pharmacie de l'Universite de Lille, 1979, Nov-17, Volume: Suppl 1

    Topics: Amisulpride; Bipolar Disorder; Day Care, Medical; Hospitals, Psychiatric; Humans; Male; Mental Disor

1979
[Chemotherapy of melancholia by sequential neuroleptic-viloxazine association].
    L'Encephale, 1976, Volume: 2, Issue:3

    Topics: Adjustment Disorders; Adult; Bipolar Disorder; Chlorpromazine; Depression; Depressive Disorder, Majo

1976
[Electroconvulsive therapy in treatment of acute life threatening catatonia in toxic epidermal necrolysis (Lyell syndrome)].
    Der Nervenarzt, 1992, Volume: 63, Issue:5

    Topics: Adult; Bipolar Disorder; Carbamazepine; Catatonia; Drug Therapy, Combination; Electroconvulsive Ther

1992
Relationship between plasma level and therapeutic effect of sulpiride.
    The Keio journal of medicine, 1986, Volume: 35, Issue:3

    Topics: Adult; Bipolar Disorder; Depressive Disorder; Dopamine beta-Hydroxylase; Female; Humans; Male; Metho

1986
[Clinical trial with sulpiride].
    Arquivos de neuro-psiquiatria, 1974, Volume: 32, Issue:3

    Topics: Adult; Bipolar Disorder; Drug Evaluation; Humans; Injections, Intramuscular; Middle Aged; Psychoses,

1974