sulpiride has been researched along with Anxiety in 43 studies
Sulpiride: A dopamine D2-receptor antagonist. It has been used therapeutically as an antidepressant, antipsychotic, and as a digestive aid. (From Merck Index, 11th ed)
sulpiride : A member of the class of benzamides obtained from formal condensation between the carboxy group of 2-methoxy-5-sulfamoylbenzoic acid and the primary amino group of (1-ethylpyrrolidin-2-yl)methylamine.
Anxiety: Feelings or emotions of dread, apprehension, and impending disaster but not disabling as with ANXIETY DISORDERS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The aim of this study was to explore effects on anxiety-like behavior of the D2 dopamine receptor agonist, quinpirole and of the D2 dopamine receptor antagonist, sulpiride given alone or in combination with a low dose of 17β-estradiol (17β-E2) to ovariectomized (OVX) rats." | 3.79 | Anxiolytic-like effect of quinpirole in combination with a low dose of 17β-estradiol in ovariectomized rats. ( Fedotova, J, 2013) |
| "Anxiety-related behaviors increase histamine and dopamine release in the brain." | 3.79 | Involvement of the dorsal hippocampal dopamine D2 receptors in histamine-induced anxiogenic-like effects in mice. ( Ayazi, E; Piri, M; Zarrindast, MR, 2013) |
| "Involvement of the dopamine receptors in the basolateral amygdala (BLA) in the effects of histamine on anxiety-like behaviors of the elevated plus maze in male Wistar rats was investigated." | 3.78 | D1 and D2 dopaminergic systems in the rat basolateral amygdala are involved in anxiogenic-like effects induced by histamine. ( Ahmadi, S; Bananej, M; Karimi-Sori, A; Zarrindast, MR, 2012) |
| "Microinjections of glutamic acid, serotonin, and sulpiride in the ventromedial hypothalamus reduced anxiety in an illuminated platform avoidance task in rats, while dopamine, apomorphine, picrotoxin, and memantine increased it." | 3.71 | The role of neurochemical mechanisms of ventromedial hypothalamus in various models of anxiety in rats. ( Gordienko, DV; Krivobok, GK; Pankrat'ev, DV; Talalaenko, AN; Zinkovich, II, 2001) |
| "The pharmacological treatment of fibromyalgia is limited to a few drugs that have been demonstrated to be moderately effective in some but not all dimensions of the disease." | 2.50 | Current status of atypical antipsychotics for the treatment of fibromyalgia. ( Calandre, EP; Rico-Villademoros, F; Slim, M, 2014) |
| "Treatment with sulpiride further probed the pharmacological basis of long-term behavioural changes." | 1.40 | The dopamine D2/D3 receptor agonist quinpirole increases checking-like behaviour in an operant observing response task with uncertain reinforcement: a novel possible model of OCD. ( d'Angelo, LS; Day, JO; Dongelmans, ML; Eagle, DM; Mar, AC; Morein-Zamir, S; Noble, CA; Noschang, C; Robbins, TW; Theobald, DE; Urcelay, GP, 2014) |
| "Cholestasis was induced by ligation of the main bile duct." | 1.39 | Differential mechanisms of opioidergic and dopaminergic systems of the ventral hippocampus (CA₃) in anxiolytic-like behaviors induced by cholestasis in mice. ( Kafi, F; Nasehi, M; Zarrindast, MR, 2013) |
| "Results of a comparative study of the effects of chronic administration of the D2-receptor agonist quinperole (0." | 1.38 | [D2-type dopaminergic receptors and anxiety-depression-like behavior in female rats]. ( Fedotova, IuO, 2012) |
| "The objective of this study was to investigate the effects of chronic administration of a semi-purified extract (Purified Extract A--PEA; 4, 8, or 16 mg/kg) of PAULLINIA CUPANA (guaraná) seeds on rats submitted to the elevated T-maze (ETM) model of generalized anxiety and panic disorders." | 1.37 | Anxiolytic effects of a semipurified constituent of guaraná seeds on rats in the elevated T-maze test. ( Audi, EA; Biesdorf de Almeida, C; de Mello, JC; Klein, T; Roncon, CM, 2011) |
| "Pretreatment with diazepam (0." | 1.31 | Anxiogenic-like effects limit rewarding effects of cocaine in balb/cbyj mice. ( Cazala, P; David, V; Gold, LH; Koob, GF, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (16.28) | 18.7374 |
| 1990's | 4 (9.30) | 18.2507 |
| 2000's | 8 (18.60) | 29.6817 |
| 2010's | 21 (48.84) | 24.3611 |
| 2020's | 3 (6.98) | 2.80 |
| Authors | Studies |
|---|---|
| Zarrindast, MR | 10 |
| Fazli-Tabaei, S | 1 |
| Khakpai, F | 1 |
| László, K | 1 |
| Péczely, L | 1 |
| Géczi, F | 1 |
| Kovács, A | 1 |
| Zagoracz, O | 1 |
| Ollmann, T | 1 |
| Kertes, E | 1 |
| Kállai, V | 1 |
| László, B | 1 |
| Berta, B | 1 |
| Karádi, Z | 1 |
| Lénárd, L | 1 |
| Peng, B | 1 |
| Xu, Q | 1 |
| Liu, J | 1 |
| Guo, S | 1 |
| Borgland, SL | 1 |
| Liu, S | 1 |
| Ebrahimi-Ghiri, M | 1 |
| Nasehi, M | 4 |
| Nguyen, D | 1 |
| Alushaj, E | 1 |
| Erb, S | 1 |
| Ito, R | 1 |
| Magdaleno-Madrigal, VM | 1 |
| Morales-Mulia, S | 1 |
| Nicolini, H | 1 |
| Genis-Mendoza, A | 1 |
| Cázares-Martínez Claudia, E | 1 |
| Pérez-Luna José, M | 1 |
| Morales-Mulia, M | 1 |
| Fedotova, J | 1 |
| Piri, M | 1 |
| Ayazi, E | 1 |
| Kafi, F | 1 |
| Becker, S | 1 |
| Ceko, M | 1 |
| Louis-Foster, M | 1 |
| Elfassy, NM | 1 |
| Leyton, M | 1 |
| Shir, Y | 1 |
| Schweinhardt, P | 1 |
| Eagle, DM | 1 |
| Noschang, C | 1 |
| d'Angelo, LS | 1 |
| Noble, CA | 1 |
| Day, JO | 1 |
| Dongelmans, ML | 1 |
| Theobald, DE | 1 |
| Mar, AC | 1 |
| Urcelay, GP | 1 |
| Morein-Zamir, S | 1 |
| Robbins, TW | 1 |
| Rico-Villademoros, F | 2 |
| Calandre, EP | 2 |
| Slim, M | 1 |
| Ishola, IO | 1 |
| Awodele, O | 1 |
| Eluogu, CO | 1 |
| Rezayof, A | 2 |
| Hosseini, SS | 1 |
| Hwang, SS | 1 |
| Jung, DC | 1 |
| Ahn, YM | 1 |
| Kim, SH | 1 |
| Kim, YS | 1 |
| Naghdi-Sedeh, N | 1 |
| Sahraei, H | 1 |
| Bahrami, F | 1 |
| Asadi, F | 1 |
| Mahboobi, S | 1 |
| Sadat-Shirazi, MS | 1 |
| Ahmadi, S | 2 |
| Roncon, CM | 1 |
| Biesdorf de Almeida, C | 1 |
| Klein, T | 1 |
| de Mello, JC | 1 |
| Audi, EA | 1 |
| Bananej, M | 1 |
| Karimi-Sori, A | 1 |
| Savio, LE | 1 |
| Vuaden, FC | 1 |
| Piato, AL | 1 |
| Bonan, CD | 1 |
| Wyse, AT | 1 |
| Rickards, H | 1 |
| Cavanna, AE | 1 |
| Worrall, R | 1 |
| Fedotova, IuO | 1 |
| Rodriguez-Lopez, CM | 1 |
| Morillas-Arques, P | 1 |
| Vilchez, JS | 1 |
| Hidalgo, J | 1 |
| Pournaghshband, M | 1 |
| Yekta, BG | 1 |
| Eslahi, N | 1 |
| Rostami, P | 1 |
| Zahmatkesh, M | 1 |
| Wall, PM | 1 |
| Blanchard, RJ | 1 |
| Yang, M | 1 |
| Blanchard, DC | 1 |
| Talalaenko, AN | 2 |
| Pankrat'ev, DV | 2 |
| Goncharenko, NV | 1 |
| Kotler, M | 1 |
| Strous, RD | 1 |
| Reznik, I | 1 |
| Shwartz, S | 1 |
| Weizman, A | 1 |
| Spivak, B | 1 |
| Grandi, M | 1 |
| Sighinolfi, R | 1 |
| Cagarelli, R | 1 |
| Ferretti, G | 1 |
| Borghi, A | 1 |
| Greco, M | 1 |
| Della Casa, L | 1 |
| Maier, W | 1 |
| Benkert, O | 1 |
| Rodgers, RJ | 1 |
| Nikulina, EM | 1 |
| Cole, JC | 1 |
| Mizuki, Y | 1 |
| Suetsugi, M | 1 |
| Ushijima, I | 1 |
| Yamada, M | 1 |
| Paoletti, AM | 1 |
| Floris, S | 1 |
| Mannias, M | 1 |
| Orrù, M | 1 |
| Crippa, D | 1 |
| Orlandi, R | 1 |
| Del Zompo M, M | 1 |
| Melis, GB | 1 |
| David, V | 1 |
| Gold, LH | 1 |
| Koob, GF | 1 |
| Cazala, P | 1 |
| Gordienko, DV | 1 |
| Zinkovich, II | 1 |
| Krivobok, GK | 1 |
| Cancela, LM | 1 |
| Basso, AM | 1 |
| Martijena, ID | 1 |
| Capriles, NR | 1 |
| Molina, VA | 1 |
| Sizaret, P | 1 |
| Moreau, C | 1 |
| Leger, JM | 1 |
| Dumond, JJ | 1 |
| Garoux, R | 1 |
| Lombertie, E | 1 |
| Dumas, M | 1 |
| Pelc, I | 1 |
| Maurel, H | 1 |
| Pujol, B | 1 |
| Planche, S | 1 |
| Simon, P | 1 |
| Panissaud, C | 1 |
| Costentin, J | 1 |
| Masciocchi, A | 1 |
| Reitano, S | 1 |
| Vanini, M | 1 |
| Cicchetti, V | 1 |
2 reviews available for sulpiride and Anxiety
| Article | Year |
|---|---|
Current status of atypical antipsychotics for the treatment of fibromyalgia.
Topics: Amisulpride; Antipsychotic Agents; Anxiety; Benzodiazepines; Comorbidity; Depression; Dibenzothiazep | 2014 |
[Psychiatric manifestations induced by dopamine precursors or antagonists].
Topics: Anxiety; Bromocriptine; Confusion; Dopamine Antagonists; Dreams; Female; Hallucinations; Humans; Lev | 1979 |
7 trials available for sulpiride and Anxiety
| Article | Year |
|---|---|
Sulpiride augmentation of olanzapine in the management of treatment-resistant chronic schizophrenia: evidence for improvement of mood symptomatology.
Topics: Adolescent; Adult; Affect; Antipsychotic Agents; Anxiety; Basal Ganglia Diseases; Benzodiazepines; C | 2004 |
Treatment of chronic depression with sulpiride: evidence of efficacy in placebo-controlled single case studies.
Topics: Adult; Anxiety; Case-Control Studies; Chronic Disease; Cross-Over Studies; Depressive Disorder; Doub | 1994 |
Differential effects of dopaminergic drugs on anxiety and arousal in healthy volunteers with high and low anxiety.
Topics: Adult; Anxiety; Arousal; Bromocriptine; Double-Blind Method; Electroencephalography; Humans; Male; S | 1997 |
Evidence that cyproterone acetate improves psychological symptoms and enhances the activity of the dopaminergic system in postmenopause.
Topics: Adult; Androgen Antagonists; Anxiety; Area Under Curve; Cyproterone Acetate; Depression; Dopamine; E | 2001 |
[Comparative study using double-blind method of sultopride and thioproperazine].
Topics: Antipsychotic Agents; Anxiety; Benzamides; Brief Psychiatric Rating Scale; Clinical Trials as Topic; | 1977 |
[Situation of sultopride among present-day neuroleptics].
Topics: Anxiety; Asthenia; Basal Ganglia Diseases; Benzamides; Bipolar Disorder; Clinical Trials as Topic; D | 1975 |
[Sulpiride and drug addiction].
Topics: Adolescent; Adult; Anxiety; Clinical Trials as Topic; Delusions; Female; Hallucinations; Humans; Lys | 1975 |
34 other studies available for sulpiride and Anxiety
| Article | Year |
|---|---|
Synergistic effect between quinpirole and L-NAME as well as sulpiride and L-arginine on the modulation of anxiety and memory processes in the 6-OHDA mouse model of Parkinson's disease: An isobologram analysis.
Topics: Adrenergic Agents; Animals; Anxiety; Arginine; Disease Models, Animal; Dopamine Agonists; Dopamine A | 2021 |
The role of D2 dopamine receptors in oxytocin induced place preference and anxiolytic effect.
Topics: Amygdala; Animals; Anti-Anxiety Agents; Anxiety; Behavior, Animal; Conditioning, Classical; Dopamine | 2020 |
Corticosterone Attenuates Reward-Seeking Behavior and Increases Anxiety via D2 Receptor Signaling in Ventral Tegmental Area Dopamine Neurons.
Topics: Animals; Anxiety; Behavior, Animal; Conditioning, Operant; Corticosterone; Dopamine D2 Receptor Anta | 2021 |
The modulatory role of accumbens and hippocampus D2 receptors in anxiety and memory.
Topics: Animals; Anxiety; Avoidance Learning; Dopamine Agonists; Dopamine Antagonists; Exploratory Behavior; | 2018 |
Dissociative effects of dorsomedial striatum D1 and D2 receptor antagonism in the regulation of anxiety and learned approach-avoidance conflict decision-making.
Topics: Animals; Anxiety; Benzazepines; Choice Behavior; Cues; Decision Making; Dopamine Antagonists; Dopami | 2019 |
Orexin-A promotes EEG changes but fails to induce anxiety in rats.
Topics: Animals; Anxiety; Anxiety Disorders; Arousal; Behavior, Animal; Dopamine D2 Receptor Antagonists; El | 2019 |
Anxiolytic-like effect of quinpirole in combination with a low dose of 17β-estradiol in ovariectomized rats.
Topics: Animals; Anxiety; Anxiety Disorders; Dopamine Agonists; Dopamine Antagonists; Dopamine D2 Receptor A | 2013 |
Involvement of the dorsal hippocampal dopamine D2 receptors in histamine-induced anxiogenic-like effects in mice.
Topics: Animals; Anxiety; Behavior, Animal; Dopamine Agonists; Dopamine Antagonists; Dopamine D2 Receptor An | 2013 |
Differential mechanisms of opioidergic and dopaminergic systems of the ventral hippocampus (CA₃) in anxiolytic-like behaviors induced by cholestasis in mice.
Topics: Animals; Anxiety; Behavior, Animal; Benzazepines; CA3 Region, Hippocampal; Cholestasis; Exploratory | 2013 |
Dopamine and pain sensitivity: neither sulpiride nor acute phenylalanine and tyrosine depletion have effects on thermal pain sensations in healthy volunteers.
Topics: Adolescent; Adult; Affect; Anxiety; Dopamine; Dopamine D2 Receptor Antagonists; Female; Healthy Volu | 2013 |
The dopamine D2/D3 receptor agonist quinpirole increases checking-like behaviour in an operant observing response task with uncertain reinforcement: a novel possible model of OCD.
Topics: Animals; Anxiety; Compulsive Behavior; Conditioning, Operant; Disease Models, Animal; Dopamine Agoni | 2014 |
Potentials of Mangifera indica in the treatment of depressive-anxiety disorders: possible mechanisms of action.
Topics: Animals; Anti-Anxiety Agents; Antidepressive Agents; Anxiety; Anxiety Disorders; Depression; Depress | 2016 |
Effects of morphine on rat behaviour in the elevated plus maze: the role of central amygdala dopamine receptors.
Topics: Amygdala; Animals; Anxiety; Apomorphine; Benzazepines; Dopamine Agonists; Dopamine Antagonists; Dopa | 2009 |
The effects of psychopathology on subjective experience of side effects of antipsychotics in patients with schizophrenia.
Topics: Adult; Amisulpride; Antipsychotic Agents; Anxiety; Benzodiazepines; Cognition Disorders; Depressive | 2010 |
The effects of dopaminergic drugs in the ventral hippocampus of rats in the nicotine-induced anxiogenic-like response.
Topics: Animals; Anxiety; Apomorphine; Benzazepines; Dopamine Agents; Dopamine D2 Receptor Antagonists; Hipp | 2010 |
Anxiolytic-like effect induced by the cannabinoid CB1 receptor agonist, arachydonilcyclopropylamide (ACPA), in the rat amygdala is mediated through the D1 and D2 dopaminergic systems.
Topics: Amygdala; Animals; Anti-Anxiety Agents; Anxiety; Apomorphine; Arachidonic Acids; Benzazepines; Dopam | 2011 |
Anxiolytic effects of a semipurified constituent of guaraná seeds on rats in the elevated T-maze test.
Topics: Animals; Anti-Anxiety Agents; Anxiety; Behavior, Animal; Disease Models, Animal; Dopamine Agents; Es | 2011 |
D1 and D2 dopaminergic systems in the rat basolateral amygdala are involved in anxiogenic-like effects induced by histamine.
Topics: Amygdala; Animals; Anxiety; Benzazepines; Histamine; Male; Maze Learning; Quinpirole; Rats; Rats, Wi | 2012 |
Behavioral changes induced by long-term proline exposure are reversed by antipsychotics in zebrafish.
Topics: 1-Pyrroline-5-Carboxylate Dehydrogenase; Amino Acid Metabolism, Inborn Errors; Animals; Antipsychoti | 2012 |
Treatment practices in Tourette syndrome: the European perspective.
Topics: Adult; Antidepressive Agents; Antipsychotic Agents; Anxiety; Aripiprazole; Atomoxetine Hydrochloride | 2012 |
[D2-type dopaminergic receptors and anxiety-depression-like behavior in female rats].
Topics: Adult; Animals; Antidepressive Agents; Anxiety; Depression; Diestrus; Dopamine; Dopamine Agonists; D | 2012 |
Amisulpride in the treatment of fibromyalgia: an uncontrolled study.
Topics: Adult; Amisulpride; Antipsychotic Agents; Anxiety; Comorbidity; Dopamine Antagonists; Female; Fibrom | 2012 |
Dopaminergic system in CA1 modulates MK-801 induced anxiolytic-like responses.
Topics: Animals; Anxiety; Benzazepines; CA1 Region, Hippocampal; Dizocilpine Maleate; Dopamine; Dopamine D2 | 2012 |
Modulation of ventral tegmental area dopamine receptors inhibit nicotine-induced anxiogenic-like behavior in the central amygdala.
Topics: Amygdala; Animals; Anxiety; Benzazepines; Dopamine Antagonists; Injections, Intraventricular; Male; | 2013 |
Infralimbic D2 receptor influences on anxiety-like behavior and active memory/attention in CD-1 mice.
Topics: Animals; Anxiety; Attention; Dopamine D2 Receptor Antagonists; Limbic System; Male; Memory; Mice; Pr | 2003 |
Neurochemical characteristics of the ventromedial hypothalamus in mediating the antiaversive effects of anxiolytics in different models of anxiety.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Anti- | 2003 |
[Liposomes of hypothalamic phospholipids: evaluation of their efficacy in subjects pretreated with sulpiride].
Topics: Adolescent; Adult; Aged; Anxiety; Depression; Double-Blind Method; Drug Therapy, Combination; Follic | 1984 |
Dopamine D1 and D2 receptor ligands modulate the behaviour of mice in the elevated plus-maze.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Anti-Anxiety Agents; Anxiety; B | 1994 |
Anxiogenic-like effects limit rewarding effects of cocaine in balb/cbyj mice.
Topics: Animals; Anti-Anxiety Agents; Anxiety; Brain; Caudate Nucleus; Cocaine; Conditioning, Operant; Diaze | 2001 |
The role of neurochemical mechanisms of ventromedial hypothalamus in various models of anxiety in rats.
Topics: Adrenergic Agents; Animals; Anxiety; Apomorphine; Avoidance Learning; Disease Models, Animal; Dopami | 2001 |
A dopaminergic mechanism is involved in the 'anxiogenic-like' response induced by chronic amphetamine treatment: a behavioral and neurochemical study.
Topics: Amphetamine; Amphetamine-Related Disorders; Animals; Anxiety; Behavior, Animal; Benzazepines; Brain; | 2001 |
[Sulpiride and psychic decompensation].
Topics: Anxiety; Autistic Disorder; Cognition Disorders; Depression; Humans; Psychotic Disorders; Sulpiride | 1976 |
Sulpiride anxiogenic-like effect inhibition by a D1 dopamine receptor antagonist.
Topics: Animals; Anxiety; Behavior, Animal; Benzazepines; Dopamine D2 Receptor Antagonists; Male; Mice; Moto | 1992 |
[Preliminary results of a controlled trial with sulpiride versus chlorimipramine in chronic schizophrenic patients with marked ideo-emotional poverty (author's transl)].
Topics: Affect; Anxiety; Chronic Disease; Clomipramine; Depression; Dibenzazepines; Humans; Mental Processes | 1974 |