sulpiride has been researched along with Allodynia in 10 studies
Sulpiride: A dopamine D2-receptor antagonist. It has been used therapeutically as an antidepressant, antipsychotic, and as a digestive aid. (From Merck Index, 11th ed)
sulpiride : A member of the class of benzamides obtained from formal condensation between the carboxy group of 2-methoxy-5-sulfamoylbenzoic acid and the primary amino group of (1-ethylpyrrolidin-2-yl)methylamine.
Excerpt | Relevance | Reference |
---|---|---|
"Metformin attenuated the visceral allodynia and increased gut permeability in animal IBS models." | 7.91 | Metformin inhibits visceral allodynia and increased gut permeability induced by stress in rats. ( Kumei, S; Miyagishi, S; Nozu, R; Nozu, T; Okumura, T; Takakusaki, K, 2019) |
"Haloperidol (HAL) is a compound that shows a high affinity with these receptors, acting as an antagonist." | 5.46 | Haloperidol Decreases Hyperalgesia and Allodynia Induced by Chronic Constriction Injury. ( Espinosa-Juárez, JV; Jaramillo-Morales, OA; López-Muñoz, FJ, 2017) |
"Moreover, profound hyperalgesia is revealed by either dopamine (DA) D1 and D2 receptor blockade by means of SCH 23390 [R-(+)-7-chloro-8-hydroxy-3-methyl-1-phenyl-2,3,4,5-tetra-hydro-1H- 3-benzazepine hydrochloride] or (-)-sulpiride, respectively, as well as after a reduction of the presynaptic synthesis of catecholamines after pretreatment of the animals with the tyrosine hydroxylase inhibitor alpha-methyl-DL-p-tyrosine (alpha-MPT)." | 5.28 | L-dopa induces opposing effects on pain in intact rats: (-)-sulpiride, SCH 23390 or alpha-methyl-DL-p-tyrosine methylester hydrochloride reveals profound hyperalgesia in large antinociceptive doses. ( Paalzow, GH, 1992) |
"Metformin attenuated the visceral allodynia and increased gut permeability in animal IBS models." | 3.91 | Metformin inhibits visceral allodynia and increased gut permeability induced by stress in rats. ( Kumei, S; Miyagishi, S; Nozu, R; Nozu, T; Okumura, T; Takakusaki, K, 2019) |
"The visceral pain was assessed by electrophysiologically measuring the threshold of abdominal muscle contractions in response to colonic distention." | 1.51 | Butyrate inhibits visceral allodynia and colonic hyperpermeability in rat models of irritable bowel syndrome. ( Miyagishi, S; Nozu, R; Nozu, T; Okumura, T; Takakusaki, K, 2019) |
"Haloperidol (HAL) is a compound that shows a high affinity with these receptors, acting as an antagonist." | 1.46 | Haloperidol Decreases Hyperalgesia and Allodynia Induced by Chronic Constriction Injury. ( Espinosa-Juárez, JV; Jaramillo-Morales, OA; López-Muñoz, FJ, 2017) |
"Levodopa has been shown to produce analgesia in various clinical and experimental settings, but its use for chronic pain treatment has not been established." | 1.36 | Levodopa analgesia in experimental neuropathic pain. ( Cobacho, N; De la Calle, JL; González-Escalada, JR; Paíno, CL, 2010) |
" Apomorphine induced a biphasic dose-response relationship, low doses producing hyperalgesia and high doses inducing antinociception." | 1.33 | Biphasic effect of apomorphine on rat nociception and effect of dopamine D2 receptor antagonists. ( Constandil, L; Eschalier, A; Hernandez, A; Laurido, C; Pelissier, T, 2006) |
"This hyperalgesia was antagonized by pretreatment with the N-methyl-D-aspartate (NMDA) receptor antagonist (+)-MK-801, suggesting involvement of NMDA receptors." | 1.29 | Noradrenaline but not dopamine involved in NMDA receptor-mediated hyperalgesia induced by theophylline in awake rats. ( Paalzow, GH, 1994) |
"Moreover, profound hyperalgesia is revealed by either dopamine (DA) D1 and D2 receptor blockade by means of SCH 23390 [R-(+)-7-chloro-8-hydroxy-3-methyl-1-phenyl-2,3,4,5-tetra-hydro-1H- 3-benzazepine hydrochloride] or (-)-sulpiride, respectively, as well as after a reduction of the presynaptic synthesis of catecholamines after pretreatment of the animals with the tyrosine hydroxylase inhibitor alpha-methyl-DL-p-tyrosine (alpha-MPT)." | 1.28 | L-dopa induces opposing effects on pain in intact rats: (-)-sulpiride, SCH 23390 or alpha-methyl-DL-p-tyrosine methylester hydrochloride reveals profound hyperalgesia in large antinociceptive doses. ( Paalzow, GH, 1992) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 2 (20.00) | 18.2507 |
2000's | 1 (10.00) | 29.6817 |
2010's | 7 (70.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Nozu, T | 2 |
Miyagishi, S | 2 |
Nozu, R | 2 |
Takakusaki, K | 2 |
Okumura, T | 2 |
Chen, M | 1 |
Hoshino, H | 1 |
Saito, S | 1 |
Yang, Y | 1 |
Obata, H | 1 |
Espinosa-Juárez, JV | 1 |
Jaramillo-Morales, OA | 1 |
López-Muñoz, FJ | 1 |
Kumei, S | 1 |
Kim, JY | 1 |
Tillu, DV | 1 |
Quinn, TL | 1 |
Mejia, GL | 1 |
Shy, A | 1 |
Asiedu, MN | 1 |
Murad, E | 1 |
Schumann, AP | 1 |
Totsch, SK | 1 |
Sorge, RE | 1 |
Mantyh, PW | 1 |
Dussor, G | 1 |
Price, TJ | 1 |
Cobacho, N | 1 |
De la Calle, JL | 1 |
González-Escalada, JR | 1 |
Paíno, CL | 1 |
Barchini, J | 1 |
Tchachaghian, S | 1 |
Shamaa, F | 1 |
Jabbur, SJ | 1 |
Meyerson, BA | 1 |
Song, Z | 1 |
Linderoth, B | 1 |
Saadé, NE | 1 |
Pelissier, T | 1 |
Laurido, C | 1 |
Hernandez, A | 1 |
Constandil, L | 1 |
Eschalier, A | 1 |
Paalzow, GH | 2 |
10 other studies available for sulpiride and Allodynia
Article | Year |
---|---|
Butyrate inhibits visceral allodynia and colonic hyperpermeability in rat models of irritable bowel syndrome.
Topics: Animals; Butyrates; Colon; Disease Models, Animal; Electrodes; Hyperalgesia; Inflammation; Irritable | 2019 |
Spinal dopaminergic involvement in the antihyperalgesic effect of antidepressants in a rat model of neuropathic pain.
Topics: Amitriptyline; Analgesics; Animals; Antidepressive Agents; Cyclopropanes; Disease Models, Animal; Do | 2017 |
Haloperidol Decreases Hyperalgesia and Allodynia Induced by Chronic Constriction Injury.
Topics: Amines; Analgesics; Animals; Antipsychotic Agents; Chronic Disease; Constriction, Pathologic; Cycloh | 2017 |
Metformin inhibits visceral allodynia and increased gut permeability induced by stress in rats.
Topics: AMP-Activated Protein Kinases; Animals; Colon; Disease Models, Animal; Domperidone; Dopamine Antagon | 2019 |
Spinal dopaminergic projections control the transition to pathological pain plasticity via a D1/D5-mediated mechanism.
Topics: Animals; Benzazepines; Carrageenan; Dinoprostone; Dopaminergic Neurons; Hyperalgesia; Interleukin-6; | 2015 |
Levodopa analgesia in experimental neuropathic pain.
Topics: Analgesics; Animals; Disease Models, Animal; Dopamine Antagonists; Dose-Response Relationship, Drug; | 2010 |
Spinal segmental and supraspinal mechanisms underlying the pain-relieving effects of spinal cord stimulation: an experimental study in a rat model of neuropathy.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Analysis of Variance; Animals; Baclofen; | 2012 |
Biphasic effect of apomorphine on rat nociception and effect of dopamine D2 receptor antagonists.
Topics: Analgesics; Animals; Apomorphine; Domperidone; Dopamine Agonists; Dopamine Antagonists; Dopamine D2 | 2006 |
Noradrenaline but not dopamine involved in NMDA receptor-mediated hyperalgesia induced by theophylline in awake rats.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Adrenergic alpha-Agonists; Adrenergic alpha-Antagonist | 1994 |
L-dopa induces opposing effects on pain in intact rats: (-)-sulpiride, SCH 23390 or alpha-methyl-DL-p-tyrosine methylester hydrochloride reveals profound hyperalgesia in large antinociceptive doses.
Topics: Analgesics; Animals; Benzazepines; Catecholamines; Drug Interactions; Electric Stimulation; Hyperalg | 1992 |