Page last updated: 2024-11-04

sulpiride and Alcohol Drinking

sulpiride has been researched along with Alcohol Drinking in 9 studies

Sulpiride: A dopamine D2-receptor antagonist. It has been used therapeutically as an antidepressant, antipsychotic, and as a digestive aid. (From Merck Index, 11th ed)
sulpiride : A member of the class of benzamides obtained from formal condensation between the carboxy group of 2-methoxy-5-sulfamoylbenzoic acid and the primary amino group of (1-ethylpyrrolidin-2-yl)methylamine.

Alcohol Drinking: Behaviors associated with the ingesting of ALCOHOLIC BEVERAGES, including social drinking.

Research Excerpts

ExcerptRelevanceReference
" Neuropharmacological studies demonstrated that local microinfusion of the D2 antagonist, sulpiride, or, at low doses, the DA releaser, d-amphetamine, could increase alcohol drinking by P rats."3.68CNS mechanisms of alcohol self-administration. ( Gatto, GJ; Levy, AD; Li, TK; Lumeng, L; McBride, WJ; Murphy, JM; Yoshimoto, K, 1993)
"[3H]sulpiride binding was significantly different only in the ventral tegmental area (VTA), where binding was approximately 20% lower in the periadolescent P rats compared with the NP rat pups."1.32Regional CNS densities of serotonin 1A and dopamine D2 receptors in periadolescent alcohol-preferring P and alcohol-nonpreferring NP rat pups. ( Li, TK; Lumeng, L; McBride, WJ; Strother, WN, 2003)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (22.22)18.2507
2000's4 (44.44)29.6817
2010's2 (22.22)24.3611
2020's1 (11.11)2.80

Authors

AuthorsStudies
Engleman, EA3
Ingraham, CM2
Rodd, ZA2
Murphy, JM6
McBride, WJ7
Ding, ZM1
Yaroslavsky, I1
Tejani-Butt, SM1
Morganstern, I1
Tejani-Butt, S1
Strother, WN1
Lumeng, L4
Li, TK4
O'Brien, CE1
Melendez, RI1
Gatto, GJ1
Levy, AD2
Yoshimoto, K1

Other Studies

9 other studies available for sulpiride and Alcohol Drinking

ArticleYear
The reinforcing effects of ethanol within the prelimbic cortex and ethanol drinking: Involvement of local dopamine D
    Drug and alcohol dependence, 2020, 09-01, Volume: 214

    Topics: Alcohol Drinking; Animals; Dopamine; Ethanol; Male; Microdialysis; Prefrontal Cortex; Receptors, Dop

2020
Voluntary alcohol consumption alters stress-induced changes in dopamine-2 receptor binding in Wistar-Kyoto rat brain.
    Pharmacology, biochemistry, and behavior, 2010, Volume: 94, Issue:3

    Topics: Alcohol Drinking; Animals; Brain; Iodine Radioisotopes; Protein Binding; Radioligand Assay; Rats; Ra

2010
Differential patterns of alcohol consumption and dopamine-2 receptor binding in Wistar-Kyoto and Wistar rats.
    Neurochemical research, 2010, Volume: 35, Issue:11

    Topics: Alcohol Drinking; Animals; Depressive Disorder; Male; Models, Animal; Rats; Rats, Inbred WKY; Rats,

2010
Regional CNS densities of serotonin 1A and dopamine D2 receptors in periadolescent alcohol-preferring P and alcohol-nonpreferring NP rat pups.
    Pharmacology, biochemistry, and behavior, 2003, Volume: 74, Issue:2

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Aging; Alcohol Drinking; Animals; Autoradiography; Central N

2003
Ethanol drinking experience attenuates (-)sulpiride-induced increases in extracellular dopamine levels in the nucleus accumbens of alcohol-preferring (P) rats.
    Alcoholism, clinical and experimental research, 2003, Volume: 27, Issue:3

    Topics: Alcohol Drinking; Animals; Dopamine; Dopamine Antagonists; Ethanol; Extracellular Space; Female; Nuc

2003
Effect of housing conditions on sulpiride-induced increases in extracellular dopamine (DA) levels in the nucleus accumbens of alcohol-preferring (P) rats.
    Brain research, 2004, Oct-01, Volume: 1022, Issue:1-2

    Topics: Alcohol Drinking; Analysis of Variance; Animals; Area Under Curve; Behavior, Animal; Central Nervous

2004
Dopamine receptor regulation of ethanol intake and extracellular dopamine levels in the ventral pallidum of alcohol preferring (P) rats.
    Drug and alcohol dependence, 2005, Mar-07, Volume: 77, Issue:3

    Topics: Alcohol Drinking; Animals; Benzazepines; Choice Behavior; Dopamine; Dopamine Antagonists; Dose-Respo

2005
CNS mechanisms of alcohol self-administration.
    Alcohol and alcoholism (Oxford, Oxfordshire). Supplement, 1993, Volume: 2

    Topics: Alcohol Drinking; Animals; Brain; Dextroamphetamine; Dopamine; Ethanol; Female; Raphe Nuclei; Rats;

1993
Microinjection of sulpiride into the nucleus accumbens increases ethanol drinking in alcohol-preferring (P) rats.
    Alcohol and alcoholism (Oxford, Oxfordshire). Supplement, 1991, Volume: 1

    Topics: Alcohol Drinking; Alcoholism; Animals; Benzazepines; Drinking Behavior; Female; Functional Lateralit

1991