sulpiride has been researched along with Akinetic-Rigid Variant of Huntington Disease in 14 studies
Sulpiride: A dopamine D2-receptor antagonist. It has been used therapeutically as an antidepressant, antipsychotic, and as a digestive aid. (From Merck Index, 11th ed)
sulpiride : A member of the class of benzamides obtained from formal condensation between the carboxy group of 2-methoxy-5-sulfamoylbenzoic acid and the primary amino group of (1-ethylpyrrolidin-2-yl)methylamine.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Eleven patients with Huntington's disease and nine patients with tardive dyskinesia participated in a randomised double-blind crossover trial of sulpiride (as sole antidopaminergic therapy) versus placebo." | 2.65 | A double blind trial of sulpiride in Huntington's disease and tardive dyskinesia. ( Marsden, CD; Quinn, N, 1984) |
| "Pretreatment with haloperidol (2 mg intramuscularly) or sulpiride (100 mg intramuscularly) 30 minutes prior to apomorphine treatment, prevented the therapeutic effect of this compound." | 2.64 | Apomorphine hydrochloride-induced improvement in Huntington's chorea: stimulation of dopamine receptor. ( Cianchetti, C; Corsini, GU; Gessa, G; Mangoni, A; Masala, C; Onali, P, 1978) |
| "Huntington's disease is a hereditary and progressive disease of the central nervous system." | 1.32 | [Frontal dysfunctions in Huntington's disease -- neuropsychology and therapy]. ( Braus, DF; Ries, S; Tost, H; Weimer, E, 2003) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (42.86) | 18.7374 |
| 1990's | 2 (14.29) | 18.2507 |
| 2000's | 5 (35.71) | 29.6817 |
| 2010's | 1 (7.14) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Choi, ML | 1 |
| Begeti, F | 1 |
| Oh, JH | 1 |
| Lee, SY | 1 |
| O'Keeffe, GC | 1 |
| Clelland, CD | 1 |
| Tyers, P | 1 |
| Cho, ZH | 1 |
| Kim, YB | 1 |
| Barker, RA | 1 |
| Lukács, A | 1 |
| Szabó, A | 1 |
| Papp, A | 1 |
| Vezér, T | 1 |
| Weimer, E | 1 |
| Ries, S | 1 |
| Tost, H | 1 |
| Braus, DF | 1 |
| Saft, C | 1 |
| Andrich, J | 1 |
| Kraus, PH | 1 |
| Przuntek, H | 1 |
| Vieregge, P | 1 |
| Tremolizzo, L | 1 |
| Rodriguez-Menendez, V | 1 |
| DiFrancesco, JC | 1 |
| Sala, G | 1 |
| Galbussera, A | 1 |
| Appollonio, I | 1 |
| Ferrarese, C | 2 |
| Frattola, L | 1 |
| Albizzati, MG | 1 |
| Alemani, A | 1 |
| Bassi, S | 1 |
| Trabucchi, M | 1 |
| Quinn, N | 2 |
| Marsden, CD | 2 |
| Levivier, M | 1 |
| Przedborski, S | 1 |
| Donatelli, L | 1 |
| Müller, EE | 1 |
| Cocchi, D | 1 |
| Mantegazza, P | 1 |
| Parati, EA | 1 |
| Caraceni, T | 1 |
| Corsini, GU | 1 |
| Onali, P | 1 |
| Masala, C | 1 |
| Cianchetti, C | 1 |
| Mangoni, A | 1 |
| Gessa, G | 1 |
| Knowling, MR | 1 |
| Wrench, W | 1 |
3 trials available for sulpiride and Akinetic-Rigid Variant of Huntington Disease
| Article | Year |
|---|---|
Acute treatment of Huntington's chorea with lisuride.
Topics: Clinical Trials as Topic; Ergolines; Female; Haloperidol; Humans; Huntington Disease; Lisuride; Male | 1983 |
A double blind trial of sulpiride in Huntington's disease and tardive dyskinesia.
Topics: Adult; Aged; Clinical Trials as Topic; Dose-Response Relationship, Drug; Double-Blind Method; Dyskin | 1984 |
Apomorphine hydrochloride-induced improvement in Huntington's chorea: stimulation of dopamine receptor.
Topics: Adult; Apomorphine; Clinical Trials as Topic; Dose-Response Relationship, Drug; Double-Blind Method; | 1978 |
11 other studies available for sulpiride and Akinetic-Rigid Variant of Huntington Disease
| Article | Year |
|---|---|
Dopaminergic manipulations and its effects on neurogenesis and motor function in a transgenic mouse model of Huntington's disease.
Topics: Animals; Brain; Corpus Striatum; Dentate Gyrus; Dopamine; Dopamine Antagonists; Female; Hippocampus; | 2014 |
Altered open field behavior in rats induced by acute administration of 3-nitropropionic acid: possible glutamatergic and dopaminergic involvement.
Topics: Animals; Behavior, Animal; Disease Models, Animal; Dizocilpine Maleate; Dopamine Agents; Dopamine D2 | 2009 |
[Frontal dysfunctions in Huntington's disease -- neuropsychology and therapy].
Topics: Adult; Amisulpride; Antipsychotic Agents; Attention; Brain; Dose-Response Relationship, Drug; Female | 2003 |
[Amisulpride in Huntington's disease].
Topics: Aged; Amisulpride; Antipsychotic Agents; Delusions; Dose-Response Relationship, Drug; Drug Administr | 2005 |
[Chorea].
Topics: Adolescent; Adult; Age Factors; Anticonvulsants; Antipsychotic Agents; Athetosis; Child; Chorea; Dia | 2007 |
Huntington's disease and HDACi: would sulpiride and valproate be of therapeutic value?
Topics: Anticonvulsants; Antipsychotic Agents; Histone Deacetylases; Humans; Huntington Disease; Motor Activ | 2007 |
Quinolinic acid-induced lesions of the rat striatum: quantitative autoradiographic binding assessment.
Topics: Animals; Autoradiography; Benzazepines; Binding, Competitive; Cholinergic Agents; Corpus Striatum; D | 1998 |
[The Cools and van Rossum theory and the pharmacology of Huntington's chorea].
Topics: Animals; Apomorphine; Brain; Cats; Dopamine; Dopamine beta-Hydroxylase; Drug Therapy, Combination; E | 1977 |
Prolactin control in Huntington's chorea.
Topics: Adult; Chlorpromazine; Humans; Huntington Disease; Hypothalamus; Middle Aged; Pituitary Gland, Anter | 1977 |
Treatment of Huntington's chorea with sulpiride.
Topics: Female; Humans; Huntington Disease; Middle Aged; Sulpiride | 1991 |
Tiapride in 12 Huntington's disease patients.
Topics: Benzamides; Humans; Huntington Disease; Sulpiride; Tiapamil Hydrochloride | 1985 |