Page last updated: 2024-11-04

sulpiride and Aggression

sulpiride has been researched along with Aggression in 13 studies

Sulpiride: A dopamine D2-receptor antagonist. It has been used therapeutically as an antidepressant, antipsychotic, and as a digestive aid. (From Merck Index, 11th ed)
sulpiride : A member of the class of benzamides obtained from formal condensation between the carboxy group of 2-methoxy-5-sulfamoylbenzoic acid and the primary amino group of (1-ethylpyrrolidin-2-yl)methylamine.

Aggression: Behavior which may be manifested by destructive and attacking action which is verbal or physical, by covert attitudes of hostility or by obstructionism.

Research Excerpts

ExcerptRelevanceReference
"Clozapine is used in the management of treatment-resistant schizophrenia and is effective in reducing aggression; however a subgroup of patients is poorly responsive."7.80Augmentation of clozapine with amisulpride: an effective therapeutic strategy for violent treatment-resistant schizophrenia patients in a UK high-security hospital. ( Basu, A; Brooman-White, RS; Das, M; Gupta, N; Hotham, JE; Humphreys, SA; Larkin, F; Ross, CC; Simpson, PJ, 2014)
"Our results are consistent with those of a similar post-hoc analysis of hostility in first-episode subjects with schizophrenia enrolled in the European First-Episode Schizophrenia Trial (EUFEST) trial, where olanzapine demonstrated advantages compared with haloperidol, quetiapine, and amisulpride."5.19Effectiveness of antipsychotic drugs against hostility in patients with schizophrenia in the Clinical Antipsychotic Trials of Intervention Effectiveness (CATIE) study. ( Citrome, L; Czobor, P; Van Dorn, RA; Volavka, J, 2014)
"To compare the effects of haloperidol, amisulpride, olanzapine, quetiapine, and ziprasidone on hostility in first-episode schizophrenia, schizoaffective disorder, or schizophreniform disorder."5.15Efficacy of antipsychotic drugs against hostility in the European First-Episode Schizophrenia Trial (EUFEST). ( Bitter, I; Czobor, P; Derks, EM; Fleischhacker, WW; Kahn, RS; Libiger, J; Volavka, J, 2011)
"Clozapine is used in the management of treatment-resistant schizophrenia and is effective in reducing aggression; however a subgroup of patients is poorly responsive."3.80Augmentation of clozapine with amisulpride: an effective therapeutic strategy for violent treatment-resistant schizophrenia patients in a UK high-security hospital. ( Basu, A; Brooman-White, RS; Das, M; Gupta, N; Hotham, JE; Humphreys, SA; Larkin, F; Ross, CC; Simpson, PJ, 2014)
"The effects of the selective D2 DA receptor antagonist, (-)eticlopride, a drug belonging to the benzamide class, were investigated on the D2 DA agonist SND 919- and CQP 201-403-induced stereotyped behaviour and on CQP 201-403-induced shaking, in rats, and on isolation-induced aggression, in mice."3.69Behavioural assessment in rats of the antipsychotic potential of the potent dopamine D2 receptor antagonist, (-)eticlopride. ( Ferrari, F; Giuliani, D, 1995)

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19905 (38.46)18.7374
1990's3 (23.08)18.2507
2000's2 (15.38)29.6817
2010's3 (23.08)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Volavka, J2
Czobor, P2
Citrome, L1
Van Dorn, RA1
Hotham, JE1
Simpson, PJ1
Brooman-White, RS1
Basu, A1
Ross, CC1
Humphreys, SA1
Larkin, F1
Gupta, N1
Das, M1
Derks, EM1
Bitter, I1
Libiger, J1
Kahn, RS1
Fleischhacker, WW1
Mauri, M1
Mancioli, A1
Rebecchi, V1
Corbetta, S1
Colombo, C1
Bono, G1
Couppis, MH1
Kennedy, CH1
Baggio, G2
Ferrari, F3
Giuliani, D1
Darondel, A1
Balthazard, C1
Sweidan, S1
Edinger, H1
Siegel, A1
Redolat, R1
Brain, PF1
Simón, VM1
Samouelian, J1
Bucci, L1

Trials

3 trials available for sulpiride and Aggression

ArticleYear
Effectiveness of antipsychotic drugs against hostility in patients with schizophrenia in the Clinical Antipsychotic Trials of Intervention Effectiveness (CATIE) study.
    CNS spectrums, 2014, Volume: 19, Issue:5

    Topics: Adult; Aggression; Amisulpride; Antipsychotic Agents; Benzodiazepines; Female; Haloperidol; Hostilit

2014
Efficacy of antipsychotic drugs against hostility in the European First-Episode Schizophrenia Trial (EUFEST).
    The Journal of clinical psychiatry, 2011, Volume: 72, Issue:7

    Topics: Adult; Aggression; Amisulpride; Antipsychotic Agents; Benzodiazepines; Dibenzothiazepines; Haloperid

2011
Amisulpride in the treatment of behavioural disturbances among patients with moderate to severe Alzheimer's disease.
    Acta neurologica Scandinavica, 2006, Volume: 114, Issue:2

    Topics: Aged; Aged, 80 and over; Aggression; Alzheimer Disease; Amisulpride; Antipsychotic Agents; Anxiety D

2006

Other Studies

10 other studies available for sulpiride and Aggression

ArticleYear
Augmentation of clozapine with amisulpride: an effective therapeutic strategy for violent treatment-resistant schizophrenia patients in a UK high-security hospital.
    CNS spectrums, 2014, Volume: 19, Issue:5

    Topics: Adult; Aggression; Amisulpride; Antipsychotic Agents; Blood Glucose; Body Mass Index; Cholesterol; C

2014
The rewarding effect of aggression is reduced by nucleus accumbens dopamine receptor antagonism in mice.
    Psychopharmacology, 2008, Volume: 197, Issue:3

    Topics: Aggression; Agonistic Behavior; Animals; Benzazepines; Brain Mapping; Conditioning, Operant; Dopamin

2008
The role of dopaminergic receptors in the behavioral effects induced by lisuride in male rats.
    Psychopharmacology, 1983, Volume: 80, Issue:1

    Topics: Aggression; Animals; Behavior, Animal; Dose-Response Relationship, Drug; Ergolines; Haloperidol; Hum

1983
Influence of lisuride on morphine withdrawal signs in the rat: a dopamine-mimetic effect.
    Psychopharmacology, 1982, Volume: 78, Issue:4

    Topics: Aggression; Animals; Apomorphine; Dopamine; Ergolines; Haloperidol; Humans; Lisuride; Male; Morphine

1982
Behavioural assessment in rats of the antipsychotic potential of the potent dopamine D2 receptor antagonist, (-)eticlopride.
    Pharmacological research, 1995, Volume: 31, Issue:5

    Topics: Aggression; Animals; Antipsychotic Agents; Behavior, Animal; Dopamine D2 Receptor Antagonists; Male;

1995
[Sultopride and the therapeutic relationship].
    Lille medical : journal de la Faculte de medecine et de pharmacie de l'Universite de Lille, 1979, Nov-17, Volume: Suppl 1

    Topics: Aggression; Amisulpride; Hospitals, Psychiatric; Humans; Impulsive Behavior; Mental Disorders; Physi

1979
D2 dopamine receptor-mediated mechanisms in the medial preoptic-anterior hypothalamus regulate effective defense behavior in the cat.
    Brain research, 1991, May-17, Volume: 549, Issue:1

    Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Affect; Aggression; Analysis of Variance

1991
Sulpiride has an antiaggressive effect in mice without markedly depressing motor activity.
    Neuropharmacology, 1991, Volume: 30, Issue:1

    Topics: Aggression; Animals; Dose-Response Relationship, Drug; Exploratory Behavior; Grooming; Male; Mice; M

1991
[Sultopride therapy of behavior disorders in a child with severe mental retardation].
    Annales de pediatrie, 1985, Mar-25, Volume: 32, Issue:3 Pt 2

    Topics: Adolescent; Aggression; Amisulpride; Humans; Intellectual Disability; Male; Psychotropic Drugs; Soci

1985
Treatment of an aggressive, compulsive adolescent with sultopride.
    The American journal of psychiatry, 1985, Volume: 142, Issue:7

    Topics: Adolescent; Aggression; Amisulpride; Child Behavior Disorders; Compulsive Behavior; Humans; Male; Ps

1985