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sulpiride and Adenoma

sulpiride has been researched along with Adenoma in 15 studies

Sulpiride: A dopamine D2-receptor antagonist. It has been used therapeutically as an antidepressant, antipsychotic, and as a digestive aid. (From Merck Index, 11th ed)
sulpiride : A member of the class of benzamides obtained from formal condensation between the carboxy group of 2-methoxy-5-sulfamoylbenzoic acid and the primary amino group of (1-ethylpyrrolidin-2-yl)methylamine.

Adenoma: A benign epithelial tumor with a glandular organization.

Research Excerpts

ExcerptRelevanceReference
"TRH, arginine, L-dopa, and sulpiride tests for PRL secretion were carried out in 18 control subjects and 20 patients with pituitary PRL-secreting adenomas before and after hypophysectomy."7.66Persistence of impaired PRL responses to sulpiride in patients with PRL secreting pituitary adenomas after successful hypophysectomy. ( Hanew, K; Kasai, M; Murakami, O; Murata, K; Sasaki, A; Sato, S; Shimizu, Y; Yoshinaga, K, 1983)
"TRH, arginine, L-dopa, and sulpiride tests for PRL secretion were carried out in 18 control subjects and 20 patients with pituitary PRL-secreting adenomas before and after hypophysectomy."3.66Persistence of impaired PRL responses to sulpiride in patients with PRL secreting pituitary adenomas after successful hypophysectomy. ( Hanew, K; Kasai, M; Murakami, O; Murata, K; Sasaki, A; Sato, S; Shimizu, Y; Yoshinaga, K, 1983)
" Preclinical evidence shows that chronic administration of antipsychotics can cause pituitary adenomas in female mice."1.34Atypical antipsychotics and pituitary neoplasms in the WHO database. ( Doraiswamy, PM; Edwards, R; Mueller-Oerlinghausen, B; Schott, G; Star, K, 2007)
"Although all of 19 prolactinomas tested expressed gp130 and LIFR subunit mRNA and immunoreactive protein, only 3 of 19 prolactinomas expressed LIF mRNA."1.32Leukemia inhibitory factor regulates prolactin secretion in prolactinoma and lactotroph cells. ( Ben-Shlomo, A; Culler, MD; Heaney, AP; Melmed, S; Miklovsky, I; Ren, SG; Yong, WH, 2003)
"When there was a pituitary adenoma or supra-sellar lesion the PRL response to sulpiride was always less than 481%."1.28[The combined stimulation test sulpiride-TRH in the investigation of prolactin secretion]. ( Claustrat, F; Dechaud, H; Miras-Mirakian, P; Pugeat, M, 1992)
"In 61 patients with pituitary adenoma, plasma TSH responses to sulpiride were significantly greater than those of normal controls, and the mean maximal increments were as follows: 1."1.26[Effect of sulpiride on plasma TSH secretion in various hypothalamo-pituitary disorders (author's transl)]. ( Sasaki, A, 1982)

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19909 (60.00)18.7374
1990's3 (20.00)18.2507
2000's3 (20.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Florio, T1
Barbieri, F1
Spaziante, R1
Zona, G1
Hofland, LJ1
van Koetsveld, PM1
Feelders, RA1
Stalla, GK1
Theodoropoulou, M1
Culler, MD2
Dong, J1
Taylor, JE1
Moreau, JP1
Saveanu, A1
Gunz, G1
Dufour, H1
Jaquet, P1
Ben-Shlomo, A1
Miklovsky, I1
Ren, SG1
Yong, WH1
Heaney, AP1
Melmed, S1
Doraiswamy, PM1
Schott, G1
Star, K1
Edwards, R1
Mueller-Oerlinghausen, B1
Hanew, K1
Sasaki, A2
Sato, S2
Kasai, M1
Murata, K2
Shimizu, Y1
Murakami, O1
Yoshinaga, K1
Arosio, M2
Moriondo, P2
Travaglini, P2
Ambrosi, B1
Beck-Peccoz, P2
Puglisi, FC1
Secchi, F1
Faglia, G3
Rocco, A2
Falaschi, P2
D'Urso, R2
De Giorgio, G1
Toffano, G1
Frajese, G1
Gasparoni, P1
Fioretti, D1
Roncato, F1
Rota, G1
Conte, N1
Aso, T1
Motohashi, K1
Yasui, T1
So, S1
Spada, A2
Bassetti, M2
Reza-Elahi, F1
Gil-Del-Alamo, P1
Vallar, L1
Ferrari, C1
Caldara, R1
Mattei, A1
Crosignani, PG1
Miras-Mirakian, P1
Claustrat, F1
Dechaud, H1
Pugeat, M1
Rosa, M1
Proietti, A1
Melis, GB1
Piscitelli, G1
Amr, S1
Ballabio, M1
Giannattasio, G1
Nissim, M1
Weintraub, BD1

Trials

1 trial available for sulpiride and Adenoma

ArticleYear
Effect of ritanserin, specific 5HT-2 antagonist, on PRL secretion in normal subjects and in different hyperprolactinaemic conditions.
    Clinical endocrinology, 1991, Volume: 34, Issue:6

    Topics: Adenoma; Female; Follicular Phase; Humans; Hyperprolactinemia; Piperidines; Pituitary Neoplasms; Pos

1991

Other Studies

14 other studies available for sulpiride and Adenoma

ArticleYear
Efficacy of a dopamine-somatostatin chimeric molecule, BIM-23A760, in the control of cell growth from primary cultures of human non-functioning pituitary adenomas: a multi-center study.
    Endocrine-related cancer, 2008, Volume: 15, Issue:2

    Topics: Adenoma; Adult; Aged; Antineoplastic Agents, Hormonal; Cabergoline; Cell Division; Dopamine; Dopamin

2008
Leukemia inhibitory factor regulates prolactin secretion in prolactinoma and lactotroph cells.
    The Journal of clinical endocrinology and metabolism, 2003, Volume: 88, Issue:2

    Topics: Adenoma; Animals; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Gene Expression; Growth In

2003
Atypical antipsychotics and pituitary neoplasms in the WHO database.
    Psychopharmacology bulletin, 2007, Volume: 40, Issue:1

    Topics: Adenoma; Adult; Adverse Drug Reaction Reporting Systems; Amisulpride; Antipsychotic Agents; Causalit

2007
Persistence of impaired PRL responses to sulpiride in patients with PRL secreting pituitary adenomas after successful hypophysectomy.
    The Tohoku journal of experimental medicine, 1983, Volume: 140, Issue:3

    Topics: Adenoma; Adolescent; Adult; Arginine; Female; Humans; Hypophysectomy; Levodopa; Male; Middle Aged; P

1983
Modifications in serum growth hormone concentration induced by sulpiride in acromegalic patients pretreated with dopamine, bromocriptine, and metergoline.
    The Journal of clinical endocrinology and metabolism, 1980, Volume: 51, Issue:3

    Topics: Acromegaly; Adenoma; Adult; Aged; Bromocriptine; Dopamine; Female; Gonadotropin-Releasing Hormone; G

1980
[Clinical and experimental studies of the mechanism of neuroendocrine action of cerebral phospholipids: the behavior of prolactin as a marker of such action].
    La Clinica terapeutica, 1981, Aug-31, Volume: 98, Issue:4

    Topics: Adenoma; Adult; Female; Humans; Liposomes; Male; Metoclopramide; Middle Aged; Phospholipids; Pituita

1981
[Effect of sulpiride on plasma TSH secretion in various hypothalamo-pituitary disorders (author's transl)].
    Nihon Naibunpi Gakkai zasshi, 1982, Mar-20, Volume: 58, Issue:3

    Topics: Adenoma; Adult; Aged; Female; Humans; Hypothalamic Diseases; Male; Middle Aged; Pituitary Diseases;

1982
[Effect of bromopride on prolactin secretion].
    La Clinica terapeutica, 1982, Aug-31, Volume: 102, Issue:4

    Topics: Adenoma; Adolescent; Adult; Female; Humans; Male; Metoclopramide; Middle Aged; Pituitary Gland; Pitu

1982
[The influence of hyperprolactin state on ovarian functions (author's transl)].
    Nihon Sanka Fujinka Gakkai zasshi, 1980, Volume: 32, Issue:9

    Topics: Adenoma; Animals; Female; Humans; Hypothalamic Neoplasms; Menstruation; Menstruation Disturbances; O

1980
Differential transduction of dopamine signal in different subtypes of human growth hormone-secreting adenomas.
    The Journal of clinical endocrinology and metabolism, 1994, Volume: 78, Issue:2

    Topics: Adenoma; Adenylyl Cyclases; Calcium; Cytosol; Dopamine; Dose-Response Relationship, Drug; Female; Gr

1994
Restoration of the prolactin response to sulpiride by metergoline administration in hyperprolactinemic patients.
    Neuroendocrinology, 1979, Volume: 29, Issue:5

    Topics: Adenoma; Adult; Amenorrhea; Bromocriptine; Dopamine; Ergolines; Female; Humans; Metergoline; Pituita

1979
[The combined stimulation test sulpiride-TRH in the investigation of prolactin secretion].
    Journal de gynecologie, obstetrique et biologie de la reproduction, 1992, Volume: 21, Issue:4

    Topics: Adenoma; Amenorrhea; Clinical Protocols; Diagnosis, Differential; Evaluation Studies as Topic; Femal

1992
Endocrine, biochemical, and morphological studies of a pituitary adenoma secreting growth hormone, thyrotropin (TSH), and alpha-subunit: evidence for secretion of TSH with increased bioactivity.
    The Journal of clinical endocrinology and metabolism, 1986, Volume: 62, Issue:4

    Topics: Adenoma; Adult; Chromatography, Gel; Dopamine; Glycoprotein Hormones, alpha Subunit; Growth Hormone;

1986
[The properties of prolactin secretion in patients with prolactin secreting pituitary adenomas].
    Nihon Naibunpi Gakkai zasshi, 1987, Aug-20, Volume: 63, Issue:8

    Topics: Adenoma; Adolescent; Adult; Arginine; Dopamine; Female; Humans; Levodopa; Male; Middle Aged; Pituita

1987