sulforaphane has been researched along with Reperfusion Injury in 18 studies
sulforaphane: from Cardaria draba L.
sulforaphane : An isothiocyanate having a 4-(methylsulfinyl)butyl group attached to the nitrogen.
Reperfusion Injury: Adverse functional, metabolic, or structural changes in tissues that result from the restoration of blood flow to the tissue (REPERFUSION) following ISCHEMIA.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The purpose of this study was to investigate the effect of Sulforaphane on ischemia/ reperfusion (IR) injury of the liver and distant organs resulting from liver blood flow arrest." | 7.81 | The effects of sulforaphane on the liver and remote organ damage in hepatic ischemia-reperfusion model formed with pringle maneuver in rats. ( Alabalik, U; Kapan, M; Kaplan, I; Oguz, A; Polat, Y; Turkoglu, A; Ulger, BV; Uslukaya, O, 2015) |
| "The sulforaphane- or albumin-treated groups showed reduced concentrations of reactive oxygen species (P < 0." | 5.62 | Sulforaphane and Albumin Attenuate Experimental Intestinal Ischemia-Reperfusion Injury. ( Bittencourt Rosas, SL; Dos Santos Valença, S; Franco, OB; Lima Castelo-Branco, MT; Lopes Lichtenberger, RC; Maran Carra, A; Pereira de Souza, HS; Ribeiro, BE; Sampaio de Holanda, G; Santana, PT; Schanaider, A, 2021) |
| "Sulforaphane (SFN)displays both anti-oxidative stress and anti-inflammatory activity." | 5.62 | Sulforaphane alleviates hepatic ischemia-reperfusion injury through promoting the activation of Nrf-2/HO-1 signaling. ( Chen, L; Jia, W; Xie, DQ; Zhang, WL, 2021) |
| "Intestinal ischemia reperfusion injury (IRI) is an inherent, unavoidable event of intestinal transplantation, contributing to allograft failure and rejection." | 5.56 | Sulforaphane Elicits Protective Effects in Intestinal Ischemia Reperfusion Injury. ( Becker, F; Brockmann, JG; Chen, Z; Hansen, U; Heitplatz, B; Mohr, A; Pascher, A, 2020) |
| "Sulforaphane treatment significantly reduced infarct volume and improved neurological scores when compared to a vehicle-treated group." | 5.46 | Sulforaphane improves outcomes and slows cerebral ischemic/reperfusion injury via inhibition of NLRP3 inflammasome activation in rats. ( He, Q; Hou, YH; Li, LY; Song, FZ; Yu, C; Zheng, J, 2017) |
| "Sulforaphane, which is a naturally occurring isothiocyanate that is present in cruciferous vegetables such as broccoli, is known to be an indirect antioxidant that acts by inducing Nrf2-dependent phase 2 enzymes." | 5.35 | Sulforaphane protects kidneys against ischemia-reperfusion injury through induction of the Nrf2-dependent phase 2 enzyme. ( Jang, KY; Kang, NI; Lee, HK; Park, BH; Park, JW; Yoon, HY, 2008) |
| "The purpose of this study was to determine the effect of sulforaphane (SFN) on hepatic ischemia reperfusion injury (HIRI) and to explore the underlying mechanisms." | 3.81 | Sulforaphane reduces apoptosis and oncosis along with protecting liver injury-induced ischemic reperfusion by activating the Nrf2/ARE pathway. ( Alina, A; Chi, X; Jin, Y; Lin, S; Shen, N; Yang, S; Zhang, R, 2015) |
| "The purpose of this study was to investigate the effect of Sulforaphane on ischemia/ reperfusion (IR) injury of the liver and distant organs resulting from liver blood flow arrest." | 3.81 | The effects of sulforaphane on the liver and remote organ damage in hepatic ischemia-reperfusion model formed with pringle maneuver in rats. ( Alabalik, U; Kapan, M; Kaplan, I; Oguz, A; Polat, Y; Turkoglu, A; Ulger, BV; Uslukaya, O, 2015) |
| "Sulforaphane (SFN) is an ITC shown to possess anticancer activities by both in vivo and epidemiological studies." | 2.52 | Sulforaphane Protects against Cardiovascular Disease via Nrf2 Activation. ( Bai, Y; Cui, J; Ma, C; Wang, X; Zhao, S; Zheng, Y, 2015) |
| "The sulforaphane- or albumin-treated groups showed reduced concentrations of reactive oxygen species (P < 0." | 1.62 | Sulforaphane and Albumin Attenuate Experimental Intestinal Ischemia-Reperfusion Injury. ( Bittencourt Rosas, SL; Dos Santos Valença, S; Franco, OB; Lima Castelo-Branco, MT; Lopes Lichtenberger, RC; Maran Carra, A; Pereira de Souza, HS; Ribeiro, BE; Sampaio de Holanda, G; Santana, PT; Schanaider, A, 2021) |
| "Sulforaphane (SFN)displays both anti-oxidative stress and anti-inflammatory activity." | 1.62 | Sulforaphane alleviates hepatic ischemia-reperfusion injury through promoting the activation of Nrf-2/HO-1 signaling. ( Chen, L; Jia, W; Xie, DQ; Zhang, WL, 2021) |
| "Intestinal ischemia reperfusion injury (IRI) is an inherent, unavoidable event of intestinal transplantation, contributing to allograft failure and rejection." | 1.56 | Sulforaphane Elicits Protective Effects in Intestinal Ischemia Reperfusion Injury. ( Becker, F; Brockmann, JG; Chen, Z; Hansen, U; Heitplatz, B; Mohr, A; Pascher, A, 2020) |
| "Sulforaphane treatment significantly reduced infarct volume and improved neurological scores when compared to a vehicle-treated group." | 1.46 | Sulforaphane improves outcomes and slows cerebral ischemic/reperfusion injury via inhibition of NLRP3 inflammasome activation in rats. ( He, Q; Hou, YH; Li, LY; Song, FZ; Yu, C; Zheng, J, 2017) |
| "Sulforaphane treatment significantly attenuated ischemic-induced loss of retinal function as compared to vehicle treated mice." | 1.42 | Protection of retinal function by sulforaphane following retinal ischemic injury. ( Ambrecht, LA; Bu, P; McDonnell, JF; Perlman, JI; Qiao, L; Zhai, Y, 2015) |
| "As sulforaphane pretreatment led to a moderate increase in peroxynitrite generation, we suggest that hormetic preconditioning underlies sulforaphane-mediated protection against stroke." | 1.39 | Sulforaphane preconditioning of the Nrf2/HO-1 defense pathway protects the cerebral vasculature against blood-brain barrier disruption and neurological deficits in stroke. ( Alfieri, A; Cash, D; Duchen, MR; Fraser, PA; Mann, GE; Modo, M; Siow, RCM; Srivastava, S; Williams, SCR, 2013) |
| "Sulforaphane is a naturally occuring antioxidative and anti-inflammatory isothiocyanat." | 1.39 | Sulforaphane decreases kidney injury after transplantation in rats: role of mitochondrial damage. ( Bruns, H; Cekauskas, A; Gross, ML; Herr, I; Jankevicius, F; Manikas, M; Schemmer, P; Strupas, K; Zorn, M, 2013) |
| "Treatment with sulforaphane inhibited an increase in the post-ischemic left ventricular end-diastolic pressure (LVEDP) and improved the post-ischemic left ventricular developed pressure (LVDP), +/-dP/dt, and coronary flow as compared with the untreated control hearts." | 1.36 | Sulforaphane protects ischemic injury of hearts through antioxidant pathway and mitochondrial K(ATP) channels. ( Chae, HJ; Chae, SW; Gao, S; Kim, DS; Kim, SH; Lee, GH; Park, BH; Piao, CS, 2010) |
| "Sulforaphane, which is a naturally occurring isothiocyanate that is present in cruciferous vegetables such as broccoli, is known to be an indirect antioxidant that acts by inducing Nrf2-dependent phase 2 enzymes." | 1.35 | Sulforaphane protects kidneys against ischemia-reperfusion injury through induction of the Nrf2-dependent phase 2 enzyme. ( Jang, KY; Kang, NI; Lee, HK; Park, BH; Park, JW; Yoon, HY, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (5.56) | 29.6817 |
| 2010's | 14 (77.78) | 24.3611 |
| 2020's | 3 (16.67) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, Z | 1 |
| Mohr, A | 1 |
| Heitplatz, B | 1 |
| Hansen, U | 1 |
| Pascher, A | 1 |
| Brockmann, JG | 1 |
| Becker, F | 1 |
| Sampaio de Holanda, G | 1 |
| Dos Santos Valença, S | 1 |
| Maran Carra, A | 1 |
| Lopes Lichtenberger, RC | 1 |
| Franco, OB | 1 |
| Ribeiro, BE | 1 |
| Bittencourt Rosas, SL | 1 |
| Santana, PT | 1 |
| Lima Castelo-Branco, MT | 1 |
| Pereira de Souza, HS | 1 |
| Schanaider, A | 1 |
| Chen, L | 2 |
| Zhang, WL | 1 |
| Xie, DQ | 1 |
| Jia, W | 1 |
| Fan, T | 1 |
| Huang, Z | 1 |
| Wang, W | 1 |
| Zhang, B | 1 |
| Xu, Y | 1 |
| Mao, Z | 1 |
| Hu, H | 1 |
| Geng, Q | 1 |
| Alfieri, A | 1 |
| Srivastava, S | 1 |
| Siow, RCM | 1 |
| Cash, D | 1 |
| Modo, M | 1 |
| Duchen, MR | 1 |
| Fraser, PA | 1 |
| Williams, SCR | 1 |
| Mann, GE | 1 |
| Cekauskas, A | 1 |
| Bruns, H | 2 |
| Manikas, M | 1 |
| Herr, I | 1 |
| Gross, ML | 1 |
| Zorn, M | 1 |
| Jankevicius, F | 1 |
| Strupas, K | 1 |
| Schemmer, P | 2 |
| Li, Z | 1 |
| Galli, U | 1 |
| Becker, LE | 1 |
| Nickkolgh, A | 1 |
| Hoffmann, K | 1 |
| Karck, M | 1 |
| Saito, H | 1 |
| Yoshimura, M | 1 |
| Saigo, C | 1 |
| Komori, M | 1 |
| Nomura, Y | 1 |
| Yamamoto, Y | 1 |
| Sagata, M | 1 |
| Wakida, A | 1 |
| Chuman, E | 1 |
| Nishi, K | 1 |
| Jono, H | 1 |
| Pan, H | 1 |
| He, M | 1 |
| Liu, R | 1 |
| Brecha, NC | 1 |
| Yu, AC | 1 |
| Pu, M | 1 |
| Shokeir, AA | 1 |
| Barakat, N | 1 |
| Hussein, AM | 1 |
| Awadalla, A | 1 |
| Harraz, AM | 1 |
| Khater, S | 1 |
| Hemmaid, K | 1 |
| Kamal, AI | 1 |
| Chi, X | 1 |
| Zhang, R | 1 |
| Shen, N | 1 |
| Jin, Y | 1 |
| Alina, A | 1 |
| Yang, S | 1 |
| Lin, S | 1 |
| Oguz, A | 1 |
| Kapan, M | 1 |
| Kaplan, I | 1 |
| Alabalik, U | 1 |
| Ulger, BV | 1 |
| Uslukaya, O | 1 |
| Turkoglu, A | 1 |
| Polat, Y | 1 |
| Ambrecht, LA | 1 |
| Perlman, JI | 1 |
| McDonnell, JF | 1 |
| Zhai, Y | 1 |
| Qiao, L | 1 |
| Bu, P | 1 |
| Bai, Y | 1 |
| Wang, X | 1 |
| Zhao, S | 1 |
| Ma, C | 1 |
| Cui, J | 1 |
| Zheng, Y | 1 |
| Yu, C | 1 |
| He, Q | 1 |
| Zheng, J | 1 |
| Li, LY | 1 |
| Hou, YH | 1 |
| Song, FZ | 1 |
| Piao, CS | 1 |
| Gao, S | 1 |
| Lee, GH | 1 |
| Kim, DS | 1 |
| Park, BH | 2 |
| Chae, SW | 1 |
| Chae, HJ | 1 |
| Kim, SH | 1 |
| Zhao, HD | 1 |
| Zhang, F | 1 |
| Shen, G | 1 |
| Li, YB | 1 |
| Li, YH | 1 |
| Jing, HR | 1 |
| Ma, LF | 1 |
| Yao, JH | 1 |
| Tian, XF | 1 |
| Yoon, HY | 1 |
| Kang, NI | 1 |
| Lee, HK | 1 |
| Jang, KY | 1 |
| Park, JW | 1 |
1 review available for sulforaphane and Reperfusion Injury
| Article | Year |
|---|---|
Sulforaphane Protects against Cardiovascular Disease via Nrf2 Activation.
Topics: Animals; Cardiovascular Diseases; Diabetes Mellitus, Experimental; Humans; Isothiocyanates; NF-E2-Re | 2015 |
17 other studies available for sulforaphane and Reperfusion Injury
| Article | Year |
|---|---|
Sulforaphane Elicits Protective Effects in Intestinal Ischemia Reperfusion Injury.
Topics: Animals; Blood Platelets; Disease Models, Animal; Intestinal Mucosa; Isothiocyanates; Leukocytes; Ma | 2020 |
Sulforaphane and Albumin Attenuate Experimental Intestinal Ischemia-Reperfusion Injury.
Topics: Albumins; Animals; Antioxidants; Disease Models, Animal; Intestines; Isothiocyanates; Male; NF-kappa | 2021 |
Sulforaphane alleviates hepatic ischemia-reperfusion injury through promoting the activation of Nrf-2/HO-1 signaling.
Topics: Animals; Heme Oxygenase-1; Isothiocyanates; Liver; Oxidative Stress; Rats; Rats, Sprague-Dawley; Rep | 2021 |
Proteasome inhibition promotes autophagy and protects from endoplasmic reticulum stress in rat alveolar macrophages exposed to hypoxia-reoxygenation injury.
Topics: Animals; Apoptosis; Autophagy; Cell Hypoxia; Cell Survival; Endoplasmic Reticulum Stress; Humans; Is | 2018 |
Sulforaphane preconditioning of the Nrf2/HO-1 defense pathway protects the cerebral vasculature against blood-brain barrier disruption and neurological deficits in stroke.
Topics: Animals; Blood-Brain Barrier; Cerebral Arteries; Gene Expression; Heme Oxygenase-1; Infarction, Midd | 2013 |
Sulforaphane decreases kidney injury after transplantation in rats: role of mitochondrial damage.
Topics: Animals; Antioxidants; Apoptosis; Isothiocyanates; Kidney; Kidney Transplantation; Male; Mitochondri | 2013 |
Sulforaphane protects hearts from early injury after experimental transplantation.
Topics: Animals; Heart; Heart Transplantation; Isothiocyanates; Male; Myocardium; Rats; Rats, Inbred Lew; Re | 2013 |
Hepatic sulfotransferase as a nephropreventing target by suppression of the uremic toxin indoxyl sulfate accumulation in ischemic acute kidney injury.
Topics: Acute Kidney Injury; Animals; Blotting, Western; Carbon; Cell Line; Chromatography, High Pressure Li | 2014 |
Sulforaphane protects rodent retinas against ischemia-reperfusion injury through the activation of the Nrf2/HO-1 antioxidant pathway.
Topics: Amacrine Cells; Animals; Antioxidants; Apoptosis; Disease Models, Animal; Heme Oxygenase-1; Inflamma | 2014 |
Activation of Nrf2 by ischemic preconditioning and sulforaphane in renal ischemia/reperfusion injury: a comparative experimental study.
Topics: Acute Kidney Injury; Animals; Combined Modality Therapy; Cytokines; Ischemic Preconditioning; Isothi | 2015 |
Sulforaphane reduces apoptosis and oncosis along with protecting liver injury-induced ischemic reperfusion by activating the Nrf2/ARE pathway.
Topics: Alanine Transaminase; Animals; Anticarcinogenic Agents; Apoptosis; Aspartate Aminotransferases; Calc | 2015 |
The effects of sulforaphane on the liver and remote organ damage in hepatic ischemia-reperfusion model formed with pringle maneuver in rats.
Topics: Animals; Anticarcinogenic Agents; Disease Models, Animal; Drug Administration Schedule; Ischemia; Is | 2015 |
Protection of retinal function by sulforaphane following retinal ischemic injury.
Topics: Animals; Disease Models, Animal; Electroretinography; Injections, Intraperitoneal; Isothiocyanates; | 2015 |
Sulforaphane improves outcomes and slows cerebral ischemic/reperfusion injury via inhibition of NLRP3 inflammasome activation in rats.
Topics: Animals; Anti-Inflammatory Agents; Brain Ischemia; Brassicaceae; Caspase 1; Down-Regulation; Humans; | 2017 |
Sulforaphane protects ischemic injury of hearts through antioxidant pathway and mitochondrial K(ATP) channels.
Topics: Animals; Antioxidants; Atrial Natriuretic Factor; bcl-2-Associated X Protein; Caspase 3; Decanoic Ac | 2010 |
Sulforaphane protects liver injury induced by intestinal ischemia reperfusion through Nrf2-ARE pathway.
Topics: Animals; Anticarcinogenic Agents; Antioxidants; Heme Oxygenase-1; Intestinal Mucosa; Intestines; Iso | 2010 |
Sulforaphane protects kidneys against ischemia-reperfusion injury through induction of the Nrf2-dependent phase 2 enzyme.
Topics: Animals; Cell Death; Cell Line; Enzyme Induction; Humans; Isothiocyanates; Kidney; Kidney Tubules, P | 2008 |