sulforaphane has been researched along with Pulmonary Fibrosis in 5 studies
sulforaphane: from Cardaria draba L.
sulforaphane : An isothiocyanate having a 4-(methylsulfinyl)butyl group attached to the nitrogen.
Pulmonary Fibrosis: A process in which normal lung tissues are progressively replaced by FIBROBLASTS and COLLAGEN causing an irreversible loss of the ability to transfer oxygen into the bloodstream via PULMONARY ALVEOLI. Patients show progressive DYSPNEA finally resulting in death.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Idiopathic pulmonary fibrosis (IPF) is a progressive and fatal disease with no effective treatment." | 5.48 | Sulforaphane attenuates pulmonary fibrosis by inhibiting the epithelial-mesenchymal transition. ( Jeong, SH; Kim, DY; Kim, YJ; Kyung, SY; Park, JW; Son, ES; Yoon, JY, 2018) |
| "Pulmonary fibrosis was induced in C57/BL6 mice by intratracheal instillation of BLM." | 5.46 | Sulforaphane prevents bleomycin‑induced pulmonary fibrosis in mice by inhibiting oxidative stress via nuclear factor erythroid 2‑related factor‑2 activation. ( Hu, Y; Ma, T; Ma, Z; Rong, G; Shi, S; Yan, B; Yang, J, 2017) |
| "Idiopathic pulmonary fibrosis (IPF) is a progressive and fatal disease with no effective treatment." | 1.48 | Sulforaphane attenuates pulmonary fibrosis by inhibiting the epithelial-mesenchymal transition. ( Jeong, SH; Kim, DY; Kim, YJ; Kyung, SY; Park, JW; Son, ES; Yoon, JY, 2018) |
| "Pulmonary fibrosis was induced in C57/BL6 mice by intratracheal instillation of BLM." | 1.46 | Sulforaphane prevents bleomycin‑induced pulmonary fibrosis in mice by inhibiting oxidative stress via nuclear factor erythroid 2‑related factor‑2 activation. ( Hu, Y; Ma, T; Ma, Z; Rong, G; Shi, S; Yan, B; Yang, J, 2017) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 5 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Yan, B | 1 |
| Ma, Z | 1 |
| Shi, S | 1 |
| Hu, Y | 1 |
| Ma, T | 1 |
| Rong, G | 1 |
| Yang, J | 1 |
| Zhang, Z | 2 |
| Qu, J | 2 |
| Zheng, C | 2 |
| Zhang, P | 2 |
| Zhou, W | 2 |
| Cui, W | 2 |
| Mo, X | 1 |
| Li, L | 1 |
| Xu, L | 2 |
| Gao, J | 2 |
| Kyung, SY | 1 |
| Kim, DY | 1 |
| Yoon, JY | 1 |
| Son, ES | 1 |
| Kim, YJ | 1 |
| Park, JW | 1 |
| Jeong, SH | 1 |
| Pekovic-Vaughan, V | 1 |
| Gibbs, J | 1 |
| Yoshitane, H | 1 |
| Yang, N | 1 |
| Pathiranage, D | 1 |
| Guo, B | 1 |
| Sagami, A | 1 |
| Taguchi, K | 1 |
| Bechtold, D | 1 |
| Loudon, A | 1 |
| Yamamoto, M | 1 |
| Chan, J | 1 |
| van der Horst, GT | 1 |
| Fukada, Y | 1 |
| Meng, QJ | 1 |
5 other studies available for sulforaphane and Pulmonary Fibrosis
| Article | Year |
|---|---|
Sulforaphane prevents bleomycin‑induced pulmonary fibrosis in mice by inhibiting oxidative stress via nuclear factor erythroid 2‑related factor‑2 activation.
Topics: Alveolar Epithelial Cells; Animals; Apoptosis; Bleomycin; Disease Models, Animal; Gene Expression; I | 2017 |
Nrf2 antioxidant pathway suppresses Numb-mediated epithelial-mesenchymal transition during pulmonary fibrosis.
Topics: Animals; Antioxidants; Bleomycin; Cell Line; Disease Models, Animal; Down-Regulation; Epithelial-Mes | 2018 |
Sulforaphane attenuates pulmonary fibrosis by inhibiting the epithelial-mesenchymal transition.
Topics: Animals; Bleomycin; Cell Line; Collagen Type I; Collagen Type IV; Epithelial-Mesenchymal Transition; | 2018 |
Downregulation of HMGB1 is required for the protective role of Nrf2 in EMT-mediated PF.
Topics: Animals; Cell Line; Down-Regulation; Epithelial-Mesenchymal Transition; Gene Expression Regulation; | 2019 |
The circadian clock regulates rhythmic activation of the NRF2/glutathione-mediated antioxidant defense pathway to modulate pulmonary fibrosis.
Topics: Animals; Anticarcinogenic Agents; Bleomycin; Circadian Clocks; E-Box Elements; Female; Gene Expressi | 2014 |