Page last updated: 2024-11-04

sulforaphane and Pneumonia

sulforaphane has been researched along with Pneumonia in 3 studies

sulforaphane: from Cardaria draba L.
sulforaphane : An isothiocyanate having a 4-(methylsulfinyl)butyl group attached to the nitrogen.

Pneumonia: Infection of the lung often accompanied by inflammation.

Research Excerpts

ExcerptRelevanceReference
"Pretreatment with sulforaphane prevented OD-induced inflammation and AHR while increasing the uptake of OD in bronchial epithelial cells."1.51Organic dust, causing both oxidative stress and Nrf2 activation, is phagocytized by bronchial epithelial cells. ( Adner, M; Chen, M; Farahnak, S; Larsson, K; Martin, JG; McGovern, T, 2019)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's3 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
McGovern, T1
Farahnak, S1
Chen, M1
Larsson, K1
Martin, JG1
Adner, M1
Duran, CG1
Burbank, AJ1
Mills, KH1
Duckworth, HR1
Aleman, MM1
Kesic, MJ1
Peden, DB1
Pan, Y1
Zhou, H1
Hernandez, ML1
Yang, Q1
Pröll, MJ1
Salilew-Wondim, D1
Zhang, R1
Tesfaye, D1
Fan, H1
Cinar, MU1
Große-Brinkhaus, C1
Tholen, E1
Islam, MA1
Hölker, M1
Schellander, K1
Uddin, MJ1
Neuhoff, C1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Down Regulation of Oxidant Induced Airway Inflammation Through Modulation of NRF2[NCT01625130]16 participants (Actual)Interventional2013-10-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

1 trial available for sulforaphane and Pneumonia

ArticleYear
A proof-of-concept clinical study examining the NRF2 activator sulforaphane against neutrophilic airway inflammation.
    Respiratory research, 2016, 07-22, Volume: 17, Issue:1

    Topics: Adolescent; Adult; Anti-Inflammatory Agents; Brassica; Cross-Over Studies; Female; Healthy Volunteer

2016

Other Studies

2 other studies available for sulforaphane and Pneumonia

ArticleYear
Organic dust, causing both oxidative stress and Nrf2 activation, is phagocytized by bronchial epithelial cells.
    American journal of physiology. Lung cellular and molecular physiology, 2019, 09-01, Volume: 317, Issue:3

    Topics: Animals; Antioxidants; Bronchi; Dust; Epithelial Cells; Inflammation; Isothiocyanates; Lung; Mice; N

2019
LPS-induced expression of CD14 in the TRIF pathway is epigenetically regulated by sulforaphane in porcine pulmonary alveolar macrophages.
    Innate immunity, 2016, Volume: 22, Issue:8

    Topics: Adaptor Proteins, Vesicular Transport; Animals; Bacterial Infections; Cells, Cultured; DNA Methylati

2016