sulforaphane has been researched along with Pachyonychia Congenita in 2 studies
sulforaphane: from Cardaria draba L.
sulforaphane : An isothiocyanate having a 4-(methylsulfinyl)butyl group attached to the nitrogen.
Pachyonychia Congenita: A group of inherited ectodermal dysplasias whose most prominent clinical feature is hypertrophic nail dystrophy resulting in PACHYONYCHIA. Several specific subtypes of pachyonychia congenita have been associated with mutations in genes that encode KERATINS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Pachyonychia congenita is caused by mutations in keratin genes and typified by dystrophic lesions affecting nails, glands, oral mucosa, and palmar-plantar epidermis." | 1.48 | Sexual Dimorphism in Response to an NRF2 Inducer in a Model for Pachyonychia Congenita. ( Coulombe, PA; Hakim, JMC; Kerns, ML; Lu, RG; Zieman, A, 2018) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kerns, ML | 2 |
| Hakim, JMC | 1 |
| Zieman, A | 1 |
| Lu, RG | 2 |
| Coulombe, PA | 2 |
| Hakim, JM | 1 |
| Guo, Y | 1 |
| Berroth, A | 1 |
| Kaspar, RL | 1 |
2 other studies available for sulforaphane and Pachyonychia Congenita
| Article | Year |
|---|---|
Sexual Dimorphism in Response to an NRF2 Inducer in a Model for Pachyonychia Congenita.
Topics: Animals; Disease Models, Animal; Estrogen Receptor alpha; Female; Glutathione; Humans; Isothiocyanat | 2018 |
Oxidative stress and dysfunctional NRF2 underlie pachyonychia congenita phenotypes.
Topics: Animals; Disease Models, Animal; Glutathione; Humans; Isothiocyanates; Keratin-16; Keratoderma, Palm | 2016 |