Page last updated: 2024-11-04

sulforaphane and Ovarian Neoplasms

sulforaphane has been researched along with Ovarian Neoplasms in 10 studies

sulforaphane: from Cardaria draba L.
sulforaphane : An isothiocyanate having a 4-(methylsulfinyl)butyl group attached to the nitrogen.

Ovarian Neoplasms: Tumors or cancer of the OVARY. These neoplasms can be benign or malignant. They are classified according to the tissue of origin, such as the surface EPITHELIUM, the stromal endocrine cells, and the totipotent GERM CELLS.

Research Excerpts

ExcerptRelevanceReference
"Higher c-Myb levels in patients with ovarian cancer lead to poor survival and our results indicate a possible effect of dietary factors EGCG and sulforaphane against c-Myb-mediated ovarian cancer progression and chemoresistance."1.51Modulation of Myb-induced NF-kB -STAT3 signaling and resulting cisplatin resistance in ovarian cancer by dietary factors. ( Li, J; Qiao, X; Tian, D; Tian, M; Zhang, L, 2019)
"Ovarian cancer is currently the most life‑threatening type of gynecological malignancy with limited treatment options."1.48Sulforaphane regulates apoptosis- and proliferation‑related signaling pathways and synergizes with cisplatin to suppress human ovarian cancer. ( Kan, SF; Sun, GX; Wang, J, 2018)
"Sulforaphane (SFN) is a major ITC present in broccoli."1.34Sulforaphane induces growth arrest and apoptosis in human ovarian cancer cells. ( Chiao, JW; Chuang, LT; Gretz, HF; Moqattash, ST; Nezhat, F; Rahaman, J, 2007)

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (20.00)29.6817
2010's7 (70.00)24.3611
2020's1 (10.00)2.80

Authors

AuthorsStudies
Gong, TT1
Liu, XD1
Zhan, ZP1
Wu, QJ1
Kan, SF1
Wang, J1
Sun, GX1
Tian, M1
Tian, D1
Qiao, X1
Li, J1
Zhang, L1
Hunakova, L2
Gronesova, P2
Horvathova, E1
Chalupa, I1
Cholujova, D2
Duraj, J1
Sedlak, J3
Pastorek, M2
Simko, V2
Takacova, M1
Barathova, M1
Bartosova, M1
Sedlakova, O1
Hudecova, S2
Krizanova, O2
Dequiedt, F1
Pastorekova, S2
Markova, J1
Csaderova, L1
Stracina, T1
Sirova, M1
Fojtu, M1
Svastova, E1
Novakova, M1
Kopacek, J1
Bryant, CS1
Kumar, S1
Chamala, S1
Shah, J1
Pal, J1
Haider, M1
Seward, S1
Qazi, AM1
Morris, R1
Semaan, A1
Shammas, MA1
Steffes, C1
Potti, RB1
Prasad, M1
Weaver, DW1
Batchu, RB1
Chen, H1
Landen, CN1
Li, Y1
Alvarez, RD1
Tollefsbol, TO1
Chaudhuri, D1
Orsulic, S1
Ashok, BT1
Chuang, LT1
Moqattash, ST1
Gretz, HF1
Nezhat, F1
Rahaman, J1
Chiao, JW1

Other Studies

10 other studies available for sulforaphane and Ovarian Neoplasms

ArticleYear
Sulforaphane enhances the cisplatin sensitivity through regulating DNA repair and accumulation of intracellular cisplatin in ovarian cancer cells.
    Experimental cell research, 2020, 08-15, Volume: 393, Issue:2

    Topics: Antineoplastic Agents; Carcinoma, Ovarian Epithelial; Cell Line, Tumor; Cell Survival; Cisplatin; DN

2020
Sulforaphane regulates apoptosis- and proliferation‑related signaling pathways and synergizes with cisplatin to suppress human ovarian cancer.
    International journal of molecular medicine, 2018, Volume: 42, Issue:5

    Topics: Animals; Antineoplastic Agents; Apoptosis; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cisplat

2018
Modulation of Myb-induced NF-kB -STAT3 signaling and resulting cisplatin resistance in ovarian cancer by dietary factors.
    Journal of cellular physiology, 2019, Volume: 234, Issue:11

    Topics: Antineoplastic Agents; Catechin; Cell Proliferation; Cisplatin; Curcumin; Drug Resistance, Neoplasm;

2019
Modulation of cisplatin sensitivity in human ovarian carcinoma A2780 and SKOV3 cell lines by sulforaphane.
    Toxicology letters, 2014, Nov-04, Volume: 230, Issue:3

    Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Cell Line, Tumor;

2014
Sulforaphane reduces molecular response to hypoxia in ovarian tumor cells independently of their resistance to chemotherapy.
    International journal of oncology, 2015, Volume: 47, Issue:1

    Topics: Anticarcinogenic Agents; Antigens, Neoplasm; Carbonic Anhydrase IX; Carbonic Anhydrases; Cell Hypoxi

2015
Sulforaphane-induced apoptosis involves the type 1 IP3 receptor.
    Oncotarget, 2016, Sep-20, Volume: 7, Issue:38

    Topics: Animals; Anticarcinogenic Agents; Antioxidant Response Elements; Apoptosis; Calcium; Cell Line, Tumo

2016
Sulforaphane induces cell cycle arrest by protecting RB-E2F-1 complex in epithelial ovarian cancer cells.
    Molecular cancer, 2010, Mar-02, Volume: 9

    Topics: Apoptosis; Cell Cycle; Cell Cycle Proteins; Cell Line, Tumor; Cell Movement; Cell Proliferation; DNA

2010
Epigallocatechin gallate and sulforaphane combination treatment induce apoptosis in paclitaxel-resistant ovarian cancer cells through hTERT and Bcl-2 down-regulation.
    Experimental cell research, 2013, Mar-10, Volume: 319, Issue:5

    Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Blotting, Western; Catechin; Cell Cycle;

2013
Antiproliferative activity of sulforaphane in Akt-overexpressing ovarian cancer cells.
    Molecular cancer therapeutics, 2007, Volume: 6, Issue:1

    Topics: Animals; Anticarcinogenic Agents; Apoptosis; Biomarkers; Cell Cycle; Cell Cycle Proteins; Cell Proli

2007
Sulforaphane induces growth arrest and apoptosis in human ovarian cancer cells.
    Acta obstetricia et gynecologica Scandinavica, 2007, Volume: 86, Issue:10

    Topics: Anticarcinogenic Agents; Apoptosis; Carcinoma; Cell Culture Techniques; Cell Cycle; Cell Proliferati

2007