Page last updated: 2024-11-04

sulforaphane and Osteosarcoma

sulforaphane has been researched along with Osteosarcoma in 6 studies

sulforaphane: from Cardaria draba L.
sulforaphane : An isothiocyanate having a 4-(methylsulfinyl)butyl group attached to the nitrogen.

Osteosarcoma: A sarcoma originating in bone-forming cells, affecting the ends of long bones. It is the most common and most malignant of sarcomas of the bones, and occurs chiefly among 10- to 25-year-old youths. (From Stedman, 25th ed)

Research Excerpts

ExcerptRelevanceReference
"Sulforaphane (SFN) has been considered a promising chemotherapeutic compound for several types of tumors by inducing apoptosis and cytostasis, but its effects (e."5.40Sulforaphane induces DNA damage and mitotic abnormalities in human osteosarcoma MG-63 cells: correlation with cell cycle arrest and apoptosis. ( Costa, M; Ferreira de Oliveira, JM; Oliveira, H; Pinho, F; Pinho, S; Pinto, P; Remédios, C; Santos, C, 2014)
"Sulforaphane (SFN) has been considered a promising chemotherapeutic compound for several types of tumors by inducing apoptosis and cytostasis, but its effects (e."1.40Sulforaphane induces DNA damage and mitotic abnormalities in human osteosarcoma MG-63 cells: correlation with cell cycle arrest and apoptosis. ( Costa, M; Ferreira de Oliveira, JM; Oliveira, H; Pinho, F; Pinho, S; Pinto, P; Remédios, C; Santos, C, 2014)
"Sulforaphane (SFN) is a naturally-occurring isothiocyanate best known for its role as an indirect antioxidant."1.40Sulforaphane induces oxidative stress and death by p53-independent mechanism: implication of impaired glutathione recycling. ( Almeida, L; Costa, M; Ferreira de Oliveira, JM; Oliveira, H; Pedrosa, T; Pimentel, F; Pinto, P; Remédios, C; Santos, C, 2014)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (33.33)29.6817
2010's4 (66.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ferreira de Oliveira, JM2
Remédios, C2
Oliveira, H2
Pinto, P2
Pinho, F1
Pinho, S1
Costa, M2
Santos, C2
Pedrosa, T1
Pimentel, F1
Almeida, L1
Rizzo, VL1
Levine, CB1
Wakshlag, JJ1
Sawai, Y1
Murata, H3
Horii, M1
Koto, K1
Matsui, T1
Horie, N2
Tsuji, Y1
Ashihara, E1
Maekawa, T1
Kubo, T3
Fushiki, S1
Matsui, TA2
Sowa, Y2
Yoshida, T1
Horinaka, M1
Wakada, M1
Nakanishi, R2
Sakabe, T2
Sakai, T2

Other Studies

6 other studies available for sulforaphane and Osteosarcoma

ArticleYear
Sulforaphane induces DNA damage and mitotic abnormalities in human osteosarcoma MG-63 cells: correlation with cell cycle arrest and apoptosis.
    Nutrition and cancer, 2014, Volume: 66, Issue:2

    Topics: Apoptosis; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Survival; Comet Assay; Cytoskeleton; DNA D

2014
Sulforaphane induces oxidative stress and death by p53-independent mechanism: implication of impaired glutathione recycling.
    PloS one, 2014, Volume: 9, Issue:3

    Topics: Antioxidants; Apoptosis; Biomarkers, Tumor; Cell Line, Tumor; Cell Survival; Enzyme Inhibitors; Glut

2014
The effects of sulforaphane on canine osteosarcoma proliferation and invasion.
    Veterinary and comparative oncology, 2017, Volume: 15, Issue:3

    Topics: Animals; Antibiotics, Antineoplastic; Anticarcinogenic Agents; Apoptosis; Bone Neoplasms; Cell Line,

2017
Effectiveness of sulforaphane as a radiosensitizer for murine osteosarcoma cells.
    Oncology reports, 2013, Volume: 29, Issue:3

    Topics: Animals; Antineoplastic Agents; Apoptosis; Bone Neoplasms; Cell Cycle Checkpoints; Cell Line, Tumor;

2013
Sulforaphane enhances TRAIL-induced apoptosis through the induction of DR5 expression in human osteosarcoma cells.
    Carcinogenesis, 2006, Volume: 27, Issue:9

    Topics: Anticarcinogenic Agents; Antineoplastic Agents; Apoptosis; Apoptosis Regulatory Proteins; Caspases;

2006
Sulforaphane induces cell cycle arrest and apoptosis in murine osteosarcoma cells in vitro and inhibits tumor growth in vivo.
    Oncology reports, 2007, Volume: 18, Issue:5

    Topics: Animals; Anticarcinogenic Agents; Apoptosis; Bone Neoplasms; Cell Division; Cyclin-Dependent Kinase

2007