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sulforaphane and Non-alcoholic Fatty Liver Disease

sulforaphane has been researched along with Non-alcoholic Fatty Liver Disease in 10 studies

sulforaphane: from Cardaria draba L.
sulforaphane : An isothiocyanate having a 4-(methylsulfinyl)butyl group attached to the nitrogen.

Non-alcoholic Fatty Liver Disease: Fatty liver finding without excessive ALCOHOL CONSUMPTION.

Research Excerpts

ExcerptRelevanceReference
"Most studies regarding the beneficial effect of sulforaphane (SFN) on non-alcoholic fatty liver disease (NAFLD) have focused on nuclear factor E2-related factor 2 (Nrf2)."8.12Sulforaphane ameliorates non-alcoholic fatty liver disease in mice by promoting FGF21/FGFR1 signaling pathway. ( Chen, W; He, Z; Ren, ZN; Wang, G; Wu, YK; Wu, YZ; Ye, XL; Zhai, QX; Zhang, H; Zhu, SL, 2022)
"Nonalcoholic fatty liver disease (NAFLD) is a major health concern."5.72Modulation of endoplasmic reticulum stress via sulforaphane-mediated AMPK upregulation against nonalcoholic fatty liver disease in rats. ( Mansour, SZ; Moawed, FSM; Moustafa, EM, 2022)
"Nonalcoholic fatty liver disease (NAFLD) is characterized by lipotoxicity and ectopic lipid deposition within hepatocytes."5.62Sulforaphane Attenuates Nonalcoholic Fatty Liver Disease by Inhibiting Hepatic Steatosis and Apoptosis. ( Li, J; Teng, W; Xie, S, 2021)
"Most studies regarding the beneficial effect of sulforaphane (SFN) on non-alcoholic fatty liver disease (NAFLD) have focused on nuclear factor E2-related factor 2 (Nrf2)."4.12Sulforaphane ameliorates non-alcoholic fatty liver disease in mice by promoting FGF21/FGFR1 signaling pathway. ( Chen, W; He, Z; Ren, ZN; Wang, G; Wu, YK; Wu, YZ; Ye, XL; Zhai, QX; Zhang, H; Zhu, SL, 2022)
" However, species, disease model, duration, SFN dosage as well as route of administration did not explain the heterogeneity among studies."2.72Sulforaphane ameliorates lipid profile in rodents: an updated systematic review and meta-analysis. ( Du, K; Fan, Y; Li, D, 2021)
"Non-alcoholic fatty liver disease (NAFLD) is a common clinicopathological condition, encompassing a range of conditions caused by lipid deposition within liver cells."2.55Antioxidant dietary approach in treatment of fatty liver: New insights and updates. ( Di Giacomo, M; Ferramosca, A; Zara, V, 2017)
"Nonalcoholic fatty liver disease (NAFLD) is a major health concern."1.72Modulation of endoplasmic reticulum stress via sulforaphane-mediated AMPK upregulation against nonalcoholic fatty liver disease in rats. ( Mansour, SZ; Moawed, FSM; Moustafa, EM, 2022)
"Sulforaphane (SFN) has been proven to be effective in alleviating many metabolic diseases, such as obesity and type 2 diabetes."1.72The protective effects of sulforaphane on high-fat diet-induced metabolic associated fatty liver disease in mice ( Hu, Q; Li, X; Lu, Y; Ma, S; Pang, X; Sun, J; Tian, S, 2022)
"Nonalcoholic fatty liver disease (NAFLD) is characterized by lipotoxicity and ectopic lipid deposition within hepatocytes."1.62Sulforaphane Attenuates Nonalcoholic Fatty Liver Disease by Inhibiting Hepatic Steatosis and Apoptosis. ( Li, J; Teng, W; Xie, S, 2021)

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's3 (30.00)24.3611
2020's7 (70.00)2.80

Authors

AuthorsStudies
Wu, YK1
Ren, ZN1
Zhu, SL1
Wu, YZ1
Wang, G1
Zhang, H1
Chen, W1
He, Z1
Ye, XL1
Zhai, QX1
Li, J1
Xie, S1
Teng, W1
Mansour, SZ1
Moustafa, EM1
Moawed, FSM1
Ma, S3
Pang, X3
Tian, S4
Sun, J3
Hu, Q3
Li, X4
Lu, Y3
Hong, L1
Xu, Y2
Wang, D1
Zhang, Q1
Xie, C1
Wu, J1
Zhong, C1
Fu, J1
Geng, S1
Huang, X1
Huangfu, B1
Hu, Y1
Xu, J1
Gao, R1
Huang, K1
He, X1
Du, K1
Fan, Y1
Li, D1
Ferramosca, A1
Di Giacomo, M1
Zara, V1
Lei, P1
Teng, C1
Huang, L1
Liu, X1
Wang, J1
Zhang, Y1
Li, B1
Shan, Y1
Yang, G1
Lee, HE1
Lee, JY1

Reviews

2 reviews available for sulforaphane and Non-alcoholic Fatty Liver Disease

ArticleYear
Sulforaphane ameliorates lipid profile in rodents: an updated systematic review and meta-analysis.
    Scientific reports, 2021, 04-08, Volume: 11, Issue:1

    Topics: Animals; Cardiovascular Diseases; Diabetes Mellitus; Isothiocyanates; Lipids; Mice; Non-alcoholic Fa

2021
Antioxidant dietary approach in treatment of fatty liver: New insights and updates.
    World journal of gastroenterology, 2017, Jun-21, Volume: 23, Issue:23

    Topics: Animals; Anthocyanins; Antioxidants; Carotenoids; Catechin; Coumestrol; Curcumin; Energy Metabolism;

2017

Other Studies

8 other studies available for sulforaphane and Non-alcoholic Fatty Liver Disease

ArticleYear
Sulforaphane ameliorates non-alcoholic fatty liver disease in mice by promoting FGF21/FGFR1 signaling pathway.
    Acta pharmacologica Sinica, 2022, Volume: 43, Issue:6

    Topics: Animals; Diet, High-Fat; Fatty Acids, Nonesterified; Fibroblast Growth Factors; Isothiocyanates; Liv

2022
Sulforaphane Attenuates Nonalcoholic Fatty Liver Disease by Inhibiting Hepatic Steatosis and Apoptosis.
    Nutrients, 2021, Dec-24, Volume: 14, Issue:1

    Topics: AMP-Activated Protein Kinases; Animals; Apoptosis; Ceramides; Diet, High-Fat; Hep G2 Cells; Humans;

2021
Modulation of endoplasmic reticulum stress via sulforaphane-mediated AMPK upregulation against nonalcoholic fatty liver disease in rats.
    Cell stress & chaperones, 2022, Volume: 27, Issue:5

    Topics: AMP-Activated Protein Kinases; Animals; Cytokines; Diet, High-Fat; Endoplasmic Reticulum Stress; Fat

2022
The protective effects of sulforaphane on high-fat diet-induced metabolic associated fatty liver disease in mice
    Food & function, 2022, Dec-13, Volume: 13, Issue:24

    Topics: Animals; Bile Acids and Salts; Diabetes Mellitus, Type 2; Diet, High-Fat; Liver; Mice; Mice, Inbred

2022
The protective effects of sulforaphane on high-fat diet-induced metabolic associated fatty liver disease in mice
    Food & function, 2022, Dec-13, Volume: 13, Issue:24

    Topics: Animals; Bile Acids and Salts; Diabetes Mellitus, Type 2; Diet, High-Fat; Liver; Mice; Mice, Inbred

2022
The protective effects of sulforaphane on high-fat diet-induced metabolic associated fatty liver disease in mice
    Food & function, 2022, Dec-13, Volume: 13, Issue:24

    Topics: Animals; Bile Acids and Salts; Diabetes Mellitus, Type 2; Diet, High-Fat; Liver; Mice; Mice, Inbred

2022
The protective effects of sulforaphane on high-fat diet-induced metabolic associated fatty liver disease in mice
    Food & function, 2022, Dec-13, Volume: 13, Issue:24

    Topics: Animals; Bile Acids and Salts; Diabetes Mellitus, Type 2; Diet, High-Fat; Liver; Mice; Mice, Inbred

2022
Sulforaphane ameliorates bisphenol A-induced hepatic lipid accumulation by inhibiting endoplasmic reticulum stress.
    Scientific reports, 2023, 01-20, Volume: 13, Issue:1

    Topics: Animals; Endoplasmic Reticulum Stress; Humans; Lipid Metabolism; Lipids; Liver; Mice; Non-alcoholic

2023
Sulforaphane Ameliorates Nonalcoholic Fatty Liver Disease Induced by High-Fat and High-Fructose Diet via LPS/TLR4 in the Gut-Liver Axis.
    Nutrients, 2023, Feb-01, Volume: 15, Issue:3

    Topics: Animals; Diet, High-Fat; Fructose; Inflammation; Lipopolysaccharides; Liver; Mice; Mice, Inbred C57B

2023
Sulforaphane Improves Lipid Metabolism by Enhancing Mitochondrial Function and Biogenesis In Vivo and In Vitro.
    Molecular nutrition & food research, 2019, Volume: 63, Issue:4

    Topics: Animals; Antioxidants; Cell Line; Diet, High-Fat; Gene Expression Regulation; Hepatocytes; Humans; I

2019
A pharmacological inhibitor of NLRP3 inflammasome prevents non-alcoholic fatty liver disease in a mouse model induced by high fat diet.
    Scientific reports, 2016, Apr-14, Volume: 6

    Topics: Administration, Oral; Animals; Diet, High-Fat; Disease Models, Animal; Enzyme Inhibitors; Inflammaso

2016