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sulforaphane and Neoplasm Metastasis

sulforaphane has been researched along with Neoplasm Metastasis in 13 studies

sulforaphane: from Cardaria draba L.
sulforaphane : An isothiocyanate having a 4-(methylsulfinyl)butyl group attached to the nitrogen.

Neoplasm Metastasis: The transfer of a neoplasm from one organ or part of the body to another remote from the primary site.

Research Excerpts

ExcerptRelevanceReference
" In this work, we show that DAOY cells, a widely used model of metastatic medulloblastoma (MBL), are highly sensitive to sulforaphane, a naturally occurring isothiocyanate from Brassica vegetables."7.72Induction of medulloblastoma cell apoptosis by sulforaphane, a dietary anticarcinogen from Brassica vegetables. ( Béliveau, R; Boivin, D; Gendron, M; Gingras, D; Moghrabi, A; Théorêt, Y, 2004)
"Sulforaphane (SFN) has antioxidant and anti‑tumor activities."5.56Sulforaphane suppresses the viability and metastasis, and promotes the apoptosis of bladder cancer cells by inhibiting the expression of FAT‑1. ( An, H; Liu, P; Wang, F; Zhang, Y, 2020)
"Metastasis and recurrence of bladder cancer are the main reasons for its poor prognosis and high mortality rates."5.39Epithelial-mesenchymal transition, a novel target of sulforaphane via COX-2/MMP2, 9/Snail, ZEB1 and miR-200c/ZEB1 pathways in human bladder cancer cells. ( Bao, Y; Feng, X; Gao, M; He, C; Li, B; Shan, Y; Wang, S; Xu, W; Zhang, L; Zhang, X, 2013)
" In this work, we show that DAOY cells, a widely used model of metastatic medulloblastoma (MBL), are highly sensitive to sulforaphane, a naturally occurring isothiocyanate from Brassica vegetables."3.72Induction of medulloblastoma cell apoptosis by sulforaphane, a dietary anticarcinogen from Brassica vegetables. ( Béliveau, R; Boivin, D; Gendron, M; Gingras, D; Moghrabi, A; Théorêt, Y, 2004)
" The aim of this in silico investigation was to predict SFN-induced adverse effects in CRC patients by computational analysis."1.72Predicting sulforaphane-induced adverse effects in colon cancer patients via in silico investigation. ( Antonijević, B; Baralić, K; Bozic, D; Bulat, Z; Ćurčić, M; Djordjević, AB; Miljaković, EA; Yang, L; Zhang, Y; Živančević, K; Đukić-Ćosić, D, 2022)
"Sulforaphane (SFN) is a naturally occurring organosulfur compound found in cruciferous vegetables such as broccoli, brussels sprouts and cabbage."1.62Sulforaphane-cisplatin combination inhibits the stemness and metastatic potential of TNBCs via down regulation of sirtuins-mediated EMT signaling axis. ( Sharma, A; Sharma, S; Shrivastava, N; Sinha, S; Vora, J, 2021)
"Sulforaphane (SFN) has antioxidant and anti‑tumor activities."1.56Sulforaphane suppresses the viability and metastasis, and promotes the apoptosis of bladder cancer cells by inhibiting the expression of FAT‑1. ( An, H; Liu, P; Wang, F; Zhang, Y, 2020)
"Metastasis and recurrence of bladder cancer are the main reasons for its poor prognosis and high mortality rates."1.39Epithelial-mesenchymal transition, a novel target of sulforaphane via COX-2/MMP2, 9/Snail, ZEB1 and miR-200c/ZEB1 pathways in human bladder cancer cells. ( Bao, Y; Feng, X; Gao, M; He, C; Li, B; Shan, Y; Wang, S; Xu, W; Zhang, L; Zhang, X, 2013)
"Sulforaphane (SFN) is a naturally occurring isothiocyanate found in cruciferous vegetables, such as broccoli, cabbage, cauliflower, etc."1.37Induction of apoptosis by sulforaphane in highly metastatic B16F-10 melanoma cells. ( Hamsa, TP; Kuttan, G; Thejass, P, 2011)
"Markers of apoptosis, angiogenesis, and metastasis were measured by immunohistochemistry."1.35Sulforaphane enhances the therapeutic potential of TRAIL in prostate cancer orthotopic model through regulation of apoptosis, metastasis, and angiogenesis. ( Ganapathy, S; Shankar, S; Srivastava, RK, 2008)

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's5 (38.46)29.6817
2010's4 (30.77)24.3611
2020's4 (30.77)2.80

Authors

AuthorsStudies
Bozic, D1
Baralić, K1
Živančević, K1
Miljaković, EA1
Ćurčić, M1
Antonijević, B1
Djordjević, AB1
Bulat, Z1
Zhang, Y2
Yang, L1
Đukić-Ćosić, D1
Wang, F1
Liu, P1
An, H1
Justin, S1
Rutz, J1
Maxeiner, S1
Chun, FK1
Juengel, E1
Blaheta, RA1
Sinha, S1
Sharma, S1
Sharma, A1
Vora, J1
Shrivastava, N1
Lee, CS1
Cho, HJ1
Jeong, YJ1
Shin, JM1
Park, KK1
Park, YY1
Bae, YS1
Chung, IK1
Kim, M1
Kim, CH1
Jin, F1
Chang, HW1
Chang, YC1
Wang, DX1
Zou, YJ1
Zhuang, XB1
Chen, SX1
Lin, Y1
Li, WL1
Lin, JJ1
Lin, ZQ1
Shankar, S1
Ganapathy, S1
Srivastava, RK1
Hamsa, TP1
Thejass, P3
Kuttan, G3
Shan, Y1
Zhang, L1
Bao, Y1
Li, B1
He, C1
Gao, M1
Feng, X1
Xu, W1
Zhang, X1
Wang, S1
Gingras, D1
Gendron, M1
Boivin, D1
Moghrabi, A1
Théorêt, Y1
Béliveau, R1
Juge, N1
Mithen, RF1
Traka, M1

Reviews

1 review available for sulforaphane and Neoplasm Metastasis

ArticleYear
Molecular basis for chemoprevention by sulforaphane: a comprehensive review.
    Cellular and molecular life sciences : CMLS, 2007, Volume: 64, Issue:9

    Topics: Anticarcinogenic Agents; Apoptosis; Diet; DNA Adducts; Enzymes; Humans; Isothiocyanates; Models, Bio

2007

Other Studies

12 other studies available for sulforaphane and Neoplasm Metastasis

ArticleYear
Predicting sulforaphane-induced adverse effects in colon cancer patients via in silico investigation.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2022, Volume: 146

    Topics: Adipocytes; Colonic Neoplasms; Gene Expression Regulation, Neoplastic; Gene Regulatory Networks; Hum

2022
Sulforaphane suppresses the viability and metastasis, and promotes the apoptosis of bladder cancer cells by inhibiting the expression of FAT‑1.
    International journal of molecular medicine, 2020, Volume: 46, Issue:3

    Topics: Anticarcinogenic Agents; Apoptosis; Cadherins; Cell Survival; Down-Regulation; Gene Expression Regul

2020
Bladder Cancer Metastasis Induced by Chronic Everolimus Application Can Be Counteracted by Sulforaphane In Vitro.
    International journal of molecular sciences, 2020, Aug-04, Volume: 21, Issue:15

    Topics: Cell Adhesion; Cell Line, Tumor; Cell Proliferation; Everolimus; Gene Expression Regulation, Neoplas

2020
Sulforaphane-cisplatin combination inhibits the stemness and metastatic potential of TNBCs via down regulation of sirtuins-mediated EMT signaling axis.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2021, Volume: 84

    Topics: Antigens, CD; Apoptosis; Cadherins; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cisplatin;

2021
Isothiocyanates inhibit the invasion and migration of C6 glioma cells by blocking FAK/JNK-mediated MMP-9 expression.
    Oncology reports, 2015, Volume: 34, Issue:6

    Topics: Cell Line, Tumor; Cell Movement; Extracellular Matrix; Focal Adhesion Kinase 1; Gene Expression Regu

2015
Sulforaphane suppresses EMT and metastasis in human lung cancer through miR-616-5p-mediated GSK3β/β-catenin signaling pathways.
    Acta pharmacologica Sinica, 2017, Volume: 38, Issue:2

    Topics: Animals; beta Catenin; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Survival; Epithelial-M

2017
Sulforaphane enhances the therapeutic potential of TRAIL in prostate cancer orthotopic model through regulation of apoptosis, metastasis, and angiogenesis.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2008, Nov-01, Volume: 14, Issue:21

    Topics: Animals; Apoptosis; Cell Proliferation; Disease Models, Animal; Drug Synergism; Isothiocyanates; Mal

2008
Induction of apoptosis by sulforaphane in highly metastatic B16F-10 melanoma cells.
    Drug and chemical toxicology, 2011, Volume: 34, Issue:3

    Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Cell Line, Tumor; Cell Survival; Cytokines; D

2011
Epithelial-mesenchymal transition, a novel target of sulforaphane via COX-2/MMP2, 9/Snail, ZEB1 and miR-200c/ZEB1 pathways in human bladder cancer cells.
    The Journal of nutritional biochemistry, 2013, Volume: 24, Issue:6

    Topics: Cell Adhesion; Cell Line, Tumor; Cell Movement; Cyclooxygenase 2; Epithelial-Mesenchymal Transition;

2013
Induction of medulloblastoma cell apoptosis by sulforaphane, a dietary anticarcinogen from Brassica vegetables.
    Cancer letters, 2004, Jan-08, Volume: 203, Issue:1

    Topics: Animals; Anticarcinogenic Agents; Apoptosis; Caspase 3; Caspase 9; Caspases; Cattle; DNA Fragmentati

2004
Antimetastatic activity of Sulforaphane.
    Life sciences, 2006, May-22, Volume: 78, Issue:26

    Topics: Animals; Antineoplastic Agents; Biomarkers, Tumor; Brassica; Cell Line; Cell Proliferation; Collagen

2006
Modulation of cell-mediated immune response in B16F-10 melanoma-induced metastatic tumor-bearing C57BL/6 mice by sulforaphane.
    Immunopharmacology and immunotoxicology, 2007, Volume: 29, Issue:2

    Topics: Animals; Antibody-Dependent Cell Cytotoxicity; Anticarcinogenic Agents; Complement System Proteins;

2007