Page last updated: 2024-11-04

sulforaphane and Multiple Myeloma

sulforaphane has been researched along with Multiple Myeloma in 2 studies

sulforaphane: from Cardaria draba L.
sulforaphane : An isothiocyanate having a 4-(methylsulfinyl)butyl group attached to the nitrogen.

Multiple Myeloma: A malignancy of mature PLASMA CELLS engaging in monoclonal immunoglobulin production. It is characterized by hyperglobulinemia, excess Bence-Jones proteins (free monoclonal IMMUNOGLOBULIN LIGHT CHAINS) in the urine, skeletal destruction, bone pain, and fractures. Other features include ANEMIA; HYPERCALCEMIA; and RENAL INSUFFICIENCY.

Research Excerpts

ExcerptRelevanceReference
"Multiple myeloma is a fatal disease characterized by clonal proliferation of plasma cells in the bone marrow."5.37Anti-tumor activity and signaling events triggered by the isothiocyanates, sulforaphane and phenethyl isothiocyanate, in multiple myeloma. ( Anderson, KC; Blotta, S; Cervi, D; Cholujova, D; Daley, JF; Delmore, J; Hideshima, T; Jakubikova, J; Kim, K; Klippel, S; Leiba, M; McMillin, DW; Mitsiades, CS; Nahar, S; Negri, J; Ooi, M; Richardson, PG; Sedlak, J, 2011)
"Multiple myeloma is a fatal disease characterized by clonal proliferation of plasma cells in the bone marrow."1.37Anti-tumor activity and signaling events triggered by the isothiocyanates, sulforaphane and phenethyl isothiocyanate, in multiple myeloma. ( Anderson, KC; Blotta, S; Cervi, D; Cholujova, D; Daley, JF; Delmore, J; Hideshima, T; Jakubikova, J; Kim, K; Klippel, S; Leiba, M; McMillin, DW; Mitsiades, CS; Nahar, S; Negri, J; Ooi, M; Richardson, PG; Sedlak, J, 2011)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Jakubikova, J1
Cervi, D1
Ooi, M1
Kim, K1
Nahar, S1
Klippel, S1
Cholujova, D1
Leiba, M1
Daley, JF1
Delmore, J1
Negri, J1
Blotta, S1
McMillin, DW1
Hideshima, T1
Richardson, PG1
Sedlak, J1
Anderson, KC1
Mitsiades, CS1
Doudican, NA1
Wen, SY1
Mazumder, A1
Orlow, SJ1

Other Studies

2 other studies available for sulforaphane and Multiple Myeloma

ArticleYear
Anti-tumor activity and signaling events triggered by the isothiocyanates, sulforaphane and phenethyl isothiocyanate, in multiple myeloma.
    Haematologica, 2011, Volume: 96, Issue:8

    Topics: Animals; Antineoplastic Agents; Apoptosis; Cell Cycle; Cell Line; Cell Proliferation; Cell Survival;

2011
Sulforaphane synergistically enhances the cytotoxicity of arsenic trioxide in multiple myeloma cells via stress-mediated pathways.
    Oncology reports, 2012, Volume: 28, Issue:5

    Topics: Antineoplastic Agents; Apoptosis; Arsenic Trioxide; Arsenicals; Caspase 3; Caspases, Initiator; Cell

2012