sulforaphane has been researched along with Mouth Neoplasms in 6 studies
sulforaphane: from Cardaria draba L.
sulforaphane : An isothiocyanate having a 4-(methylsulfinyl)butyl group attached to the nitrogen.
Mouth Neoplasms: Tumors or cancer of the MOUTH.
| Excerpt | Relevance | Reference |
|---|---|---|
| " In this study we aimed to examine whether a chemical activator of NRF2, sulforaphane (SFN), may have chemopreventive effects on oxidative stress-associated oral carcinogenesis." | 7.83 | Chemoprevention of oxidative stress-associated oral carcinogenesis by sulforaphane depends on NRF2 and the isothiocyanate moiety. ( Chen, H; Chen, X; Chen, XL; Kapita, M; Lan, A; Li, W; Liu, Y; Palko, O; Prigge, JR; Schmidt, EE; Sun, Z; Xiong, Z; Zhang, X; Zhou, S, 2016) |
| " In this study we aimed to examine whether a chemical activator of NRF2, sulforaphane (SFN), may have chemopreventive effects on oxidative stress-associated oral carcinogenesis." | 3.83 | Chemoprevention of oxidative stress-associated oral carcinogenesis by sulforaphane depends on NRF2 and the isothiocyanate moiety. ( Chen, H; Chen, X; Chen, XL; Kapita, M; Lan, A; Li, W; Liu, Y; Palko, O; Prigge, JR; Schmidt, EE; Sun, Z; Xiong, Z; Zhang, X; Zhou, S, 2016) |
| "Sulforaphane treatment of Het-1A, a normal mucosal epithelial cell line, and 4 HNSCC cell lines led to dose- and time-dependent induction of NRF2 and the NRF2 target genes NQO1 and GCLC, known mediators of carcinogen detoxication." | 2.82 | Prevention of Carcinogen-Induced Oral Cancer by Sulforaphane. ( Bauman, JE; Egner, PA; Fahey, JW; Grandis, JR; Johnson, DE; Kensler, TW; Li, C; Normolle, DP; Sen, M; Wang, L; Zang, Y, 2016) |
| "Sulforaphane treatment resulted in a dose-dependent increase in the levels of tumor suppressive miR200c." | 1.46 | Sulforaphane targets cancer stemness and tumor initiating properties in oral squamous cell carcinomas via miR-200c induction. ( Liao, YW; Liu, CM; Lu, MY; Peng, CY; Tsai, ML; Yeh, JC; Yu, CC; Yu, CH, 2017) |
| "Sulforaphane is a predominant isothiocyanate in Brassica oleracea, a family of cruciferous vegetables, and is known to be inversely related to the risk of various types of human carcinomas." | 1.37 | Sulforaphane inhibits oral carcinoma cell migration and invasion in vitro. ( Jee, HG; Kim, JB; Lee, KE; Shin, HK; Youn, YK, 2011) |
| "In this study, we found that oral squamous cell carcinomas (OSCCs) in Korean patients have a high level of COX-2 expression when compared with normal mucosa." | 1.35 | Sulforaphane enhances caspase-dependent apoptosis through inhibition of cyclooxygenase-2 expression in human oral squamous carcinoma cells and nude mouse xenograft model. ( Cho, NP; Cho, SD; Choi, IS; Choi, KH; Choi, SH; Han, HS; Jung, JY; Kim, HJ; Kong, G; Leem, DH; Moon, KS; Soh, Y, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (16.67) | 29.6817 |
| 2010's | 4 (66.67) | 24.3611 |
| 2020's | 1 (16.67) | 2.80 |
| Authors | Studies |
|---|---|
| Yu, X | 1 |
| Liu, Y | 2 |
| Pan, K | 1 |
| Sun, P | 1 |
| Li, J | 1 |
| Li, L | 1 |
| Chen, Q | 1 |
| Sun, Z | 2 |
| Liu, CM | 1 |
| Peng, CY | 1 |
| Liao, YW | 1 |
| Lu, MY | 1 |
| Tsai, ML | 1 |
| Yeh, JC | 1 |
| Yu, CH | 1 |
| Yu, CC | 1 |
| Bauman, JE | 1 |
| Zang, Y | 1 |
| Sen, M | 1 |
| Li, C | 1 |
| Wang, L | 1 |
| Egner, PA | 1 |
| Fahey, JW | 1 |
| Normolle, DP | 1 |
| Grandis, JR | 1 |
| Kensler, TW | 1 |
| Johnson, DE | 1 |
| Lan, A | 1 |
| Li, W | 1 |
| Xiong, Z | 1 |
| Zhang, X | 1 |
| Zhou, S | 1 |
| Palko, O | 1 |
| Chen, H | 1 |
| Kapita, M | 1 |
| Prigge, JR | 1 |
| Schmidt, EE | 1 |
| Chen, X | 1 |
| Chen, XL | 1 |
| Cho, NP | 1 |
| Han, HS | 1 |
| Leem, DH | 1 |
| Choi, IS | 1 |
| Jung, JY | 1 |
| Kim, HJ | 1 |
| Moon, KS | 1 |
| Choi, KH | 1 |
| Soh, Y | 1 |
| Kong, G | 1 |
| Cho, SD | 1 |
| Choi, SH | 1 |
| Jee, HG | 1 |
| Lee, KE | 1 |
| Kim, JB | 1 |
| Shin, HK | 1 |
| Youn, YK | 1 |
1 trial available for sulforaphane and Mouth Neoplasms
| Article | Year |
|---|---|
Prevention of Carcinogen-Induced Oral Cancer by Sulforaphane.
Topics: Animals; Antineoplastic Agents, Phytogenic; Brassica; Carcinogens; Cell Line; Cross-Over Studies; Hu | 2016 |
5 other studies available for sulforaphane and Mouth Neoplasms
| Article | Year |
|---|---|
Breast cancer susceptibility gene 1 regulates oxidative damage via nuclear factor erythroid 2-related factor 2 in oral cancer cells.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Apoptosis; BRCA1 Protein; Female; Humans; Isothiocyanates; Mouth Neopla | 2022 |
Sulforaphane targets cancer stemness and tumor initiating properties in oral squamous cell carcinomas via miR-200c induction.
Topics: Aldehyde Dehydrogenase 1 Family; Animals; Anticarcinogenic Agents; Carcinoma, Squamous Cell; Cell Li | 2017 |
Chemoprevention of oxidative stress-associated oral carcinogenesis by sulforaphane depends on NRF2 and the isothiocyanate moiety.
Topics: 4-Nitroquinoline-1-oxide; Animals; Anticarcinogenic Agents; Carcinogenesis; Carcinogens; Chemopreven | 2016 |
Sulforaphane enhances caspase-dependent apoptosis through inhibition of cyclooxygenase-2 expression in human oral squamous carcinoma cells and nude mouse xenograft model.
Topics: Animals; Anticarcinogenic Agents; Apoptosis; Carcinoma, Squamous Cell; Caspases; Cyclooxygenase 2 In | 2009 |
Sulforaphane inhibits oral carcinoma cell migration and invasion in vitro.
Topics: Cell Line, Tumor; Cell Movement; Gene Expression Regulation, Neoplastic; Humans; Isothiocyanates; Ma | 2011 |