sulforaphane has been researched along with Mesothelioma in 3 studies
sulforaphane: from Cardaria draba L.
sulforaphane : An isothiocyanate having a 4-(methylsulfinyl)butyl group attached to the nitrogen.
Mesothelioma: A tumor derived from mesothelial tissue (peritoneum, pleura, pericardium). It appears as broad sheets of cells, with some regions containing spindle-shaped, sarcoma-like cells and other regions showing adenomatous patterns. Pleural mesotheliomas have been linked to exposure to asbestos. (Dorland, 27th ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Treatment with sulforaphane (SFN), a diet-derived anticancer agent, reduces PRMT5/MEP50 level and H4R3me2s formation and suppresses the cancer phenotype." | 5.62 | Sulforaphane inhibits PRMT5 and MEP50 function to suppress the mesothelioma cancer cell phenotype. ( Adhikary, G; Eckert, RL; Ezeka, G; Friedberg, JS; Kandasamy, S, 2021) |
| "Sulforaphane (SFN) is an isothiocyanate compound derived from glucoraphanin, which is found in cruciferous vegetables, and has been heralded as a chemopreventive and/or chemotherapeutic agent." | 5.46 | Pro-oxidant activity of sulforaphane and cisplatin potentiates apoptosis and simultaneously promotes autophagy in malignant mesothelioma cells. ( Lee, SH; Lee, YJ, 2017) |
| "Sulforaphane treatment decreased cell viability and triggered a rapid and transient increase in the intracellular ROS levels." | 5.38 | Reactive oxygen species and PI3K/Akt signaling play key roles in the induction of Nrf2-driven heme oxygenase-1 expression in sulforaphane-treated human mesothelioma MSTO-211H cells. ( Cho, MK; Jeong, HY; Kim, YB; Lee, SH; Lee, YJ; Nam, HS; Shim, JH; Won, SY, 2012) |
| "Sulforaphane (SFN) is an isothiocyanate compound derived from glucoraphanin, which is found in cruciferous vegetables, and has been heralded as a chemopreventive and/or chemotherapeutic agent." | 1.46 | Pro-oxidant activity of sulforaphane and cisplatin potentiates apoptosis and simultaneously promotes autophagy in malignant mesothelioma cells. ( Lee, SH; Lee, YJ, 2017) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (66.67) | 24.3611 |
| 2020's | 1 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| Ezeka, G | 1 |
| Adhikary, G | 1 |
| Kandasamy, S | 1 |
| Friedberg, JS | 1 |
| Eckert, RL | 1 |
| Lee, YJ | 3 |
| Lee, SH | 2 |
| Jeong, HY | 1 |
| Kim, YB | 1 |
| Won, SY | 1 |
| Shim, JH | 1 |
| Cho, MK | 1 |
| Nam, HS | 1 |
3 other studies available for sulforaphane and Mesothelioma
| Article | Year |
|---|---|
Sulforaphane inhibits PRMT5 and MEP50 function to suppress the mesothelioma cancer cell phenotype.
Topics: Adaptor Proteins, Signal Transducing; Animals; Anticarcinogenic Agents; Gene Expression Regulation, | 2021 |
Pro-oxidant activity of sulforaphane and cisplatin potentiates apoptosis and simultaneously promotes autophagy in malignant mesothelioma cells.
Topics: Acetylcysteine; Antioxidants; Apoptosis; Autophagy; bcl-2-Associated X Protein; Cell Cycle Checkpoin | 2017 |
Reactive oxygen species and PI3K/Akt signaling play key roles in the induction of Nrf2-driven heme oxygenase-1 expression in sulforaphane-treated human mesothelioma MSTO-211H cells.
Topics: Cell Line, Tumor; Cell Survival; Dose-Response Relationship, Drug; Gene Expression Regulation, Enzym | 2012 |