Page last updated: 2024-11-04

sulforaphane and Memory Disorders

sulforaphane has been researched along with Memory Disorders in 9 studies

sulforaphane: from Cardaria draba L.
sulforaphane : An isothiocyanate having a 4-(methylsulfinyl)butyl group attached to the nitrogen.

Memory Disorders: Disturbances in registering an impression, in the retention of an acquired impression, or in the recall of an impression. Memory impairments are associated with DEMENTIA; CRANIOCEREBRAL TRAUMA; ENCEPHALITIS; ALCOHOLISM (see also ALCOHOL AMNESTIC DISORDER); SCHIZOPHRENIA; and other conditions.

Research Excerpts

ExcerptRelevanceReference
"Okadaic acid (OKA) causes memory impairment and attenuates nuclear factor erythroid 2-related factor 2 (Nrf2) along with oxidative stress and neuroinflammation in rats."3.83Sulforaphane Ameliorates Okadaic Acid-Induced Memory Impairment in Rats by Activating the Nrf2/HO-1 Antioxidant Pathway. ( Dwivedi, S; Hanif, K; Nath, C; Rajasekar, N; Shukla, R, 2016)
"Sulforaphane is a type of organosulfur compound known as an isothiocyanate."1.62Sulforaphane enhances long-term potentiation and ameliorate scopolamine-induced memory impairment. ( Choi, GW; Choi, GY; Hwang, ES; Hwang, Y; Kim, BI; Kim, HB; Maeng, S; Park, H; Park, HS; Park, JH; Park, KS; Sul, JY, 2021)
"Sulforaphane is an herbal isothiocyanate enriched in cruciferous vegetables."1.48Sulforaphane Upregulates the Heat Shock Protein Co-Chaperone CHIP and Clears Amyloid-β and Tau in a Mouse Model of Alzheimer's Disease. ( Choi, BR; Han, JS; Kim, J; LaFerla, FM; Lee, KW; Lee, S; Park, JHY, 2018)
"Sulforaphane (SFN) is a natural compound that displays antioxidant and anti-inflammatory activities."1.42Sulforaphane rescues memory dysfunction and synaptic and mitochondrial alterations induced by brain iron accumulation. ( Aguzzoli, C; Bogo, MR; Dargél, VA; de Freitas, BS; de Lima, MN; Falavigna, L; Florian, PZ; Kist, LW; Köbe, LM; Lavich, IC; Piffero, B; Schröder, N, 2015)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's6 (66.67)24.3611
2020's3 (33.33)2.80

Authors

AuthorsStudies
Kim, HJ1
Jang, BK1
Park, JH2
Choi, JW1
Park, SJ1
Byeon, SR1
Pae, AN1
Lee, YS1
Cheong, E1
Park, KD1
Kim, J5
Park, HS1
Hwang, ES1
Choi, GY1
Kim, HB1
Park, KS1
Sul, JY1
Hwang, Y1
Choi, GW1
Kim, BI1
Park, H1
Maeng, S1
Sunkaria, A1
Bhardwaj, S1
Yadav, A1
Halder, A1
Sandhir, R1
Lee, S2
Choi, BR2
LaFerla, FM1
Park, JHY1
Han, JS2
Lee, KW2
Gao, J1
Xiong, B1
Zhang, B1
Li, S1
Huang, N1
Zhan, G1
Jiang, R1
Yang, L1
Wu, Y1
Miao, L1
Zhu, B1
Yang, C1
Luo, A1
Seo, SG1
Lavich, IC1
de Freitas, BS1
Kist, LW1
Falavigna, L1
Dargél, VA1
Köbe, LM1
Aguzzoli, C1
Piffero, B1
Florian, PZ1
Bogo, MR1
de Lima, MN1
Schröder, N1
Dwivedi, S1
Rajasekar, N1
Hanif, K1
Nath, C1
Shukla, R1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Randomized,Double-blind, Placebo-controlled, Efficacy and Safety Study of Sulforaphane in Patients With Prodromal to Mild Alzheimer's Disease[NCT04213391]160 participants (Anticipated)Interventional2020-05-10Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for sulforaphane and Memory Disorders

ArticleYear
Pre-Clinical Neuroprotective Evidences and Plausible Mechanisms of Sulforaphane in Alzheimer's Disease.
    International journal of molecular sciences, 2021, Mar-13, Volume: 22, Issue:6

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Biomarkers; Cell Line, Tumor; Disease Models, Ani

2021

Other Studies

8 other studies available for sulforaphane and Memory Disorders

ArticleYear
A novel chalcone derivative as Nrf2 activator attenuates learning and memory impairment in a scopolamine-induced mouse model.
    European journal of medicinal chemistry, 2020, Jan-01, Volume: 185

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cell Survival; Cells, Cultured; Chalcone; Disease

2020
Sulforaphane enhances long-term potentiation and ameliorate scopolamine-induced memory impairment.
    Physiology & behavior, 2021, 09-01, Volume: 238

    Topics: Animals; Avoidance Learning; Hippocampus; Humans; Isothiocyanates; Long-Term Potentiation; Maze Lear

2021
Sulforaphane attenuates postnatal proteasome inhibition and improves spatial learning in adult mice.
    The Journal of nutritional biochemistry, 2018, Volume: 51

    Topics: Animals; Animals, Newborn; CA3 Region, Hippocampal; Cell Line, Tumor; Dentate Gyrus; Gene Expression

2018
Sulforaphane Upregulates the Heat Shock Protein Co-Chaperone CHIP and Clears Amyloid-β and Tau in a Mouse Model of Alzheimer's Disease.
    Molecular nutrition & food research, 2018, Volume: 62, Issue:12

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Cerebral Cortex; Disease Models, Animal; Female;

2018
Sulforaphane Alleviates Lipopolysaccharide-induced Spatial Learning and Memory Dysfunction in Mice: The Role of BDNF-mTOR Signaling Pathway.
    Neuroscience, 2018, 09-15, Volume: 388

    Topics: Animals; Brain-Derived Neurotrophic Factor; Hippocampus; Inflammation; Isothiocyanates; Learning Dis

2018
Sulforaphane alleviates scopolamine-induced memory impairment in mice.
    Pharmacological research, 2014, Volume: 85

    Topics: Acetylcholine; Acetylcholinesterase; Animals; Cells, Cultured; Choline O-Acetyltransferase; Female;

2014
Sulforaphane rescues memory dysfunction and synaptic and mitochondrial alterations induced by brain iron accumulation.
    Neuroscience, 2015, Aug-20, Volume: 301

    Topics: Animals; Animals, Newborn; Anticarcinogenic Agents; Brain; Catalase; Disease Models, Animal; Dynamin

2015
Sulforaphane Ameliorates Okadaic Acid-Induced Memory Impairment in Rats by Activating the Nrf2/HO-1 Antioxidant Pathway.
    Molecular neurobiology, 2016, Volume: 53, Issue:8

    Topics: Animals; Antioxidants; Apoptosis; Biomarkers; Cell Line, Tumor; Cell Survival; Glutamate-Cysteine Li

2016