sulforaphane has been researched along with Malignant Melanoma in 10 studies
sulforaphane: from Cardaria draba L.
sulforaphane : An isothiocyanate having a 4-(methylsulfinyl)butyl group attached to the nitrogen.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We have utilised an in vitro model of malignant melanoma [consisting of human (A375, Hs294T, VMM1) and murine (B16F-10) melanoma cell lines as well as a non-melanoma (A431) and a non-tumorigenic immortalised keratinocyte (HaCaT) cell line] exposed to sulforaphane or iberin." | 8.02 | Sulforaphane and iberin are potent epigenetic modulators of histone acetylation and methylation in malignant melanoma. ( Franco, R; Mitsiogianni, M; Panayiotidis, MI; Pappa, A; Trafalis, DT; Zoumpourlis, V, 2021) |
| "Atypical nevi were photographed on days 1 and 28, and plasma and nevus samples were taken on days 1, 2, and 28." | 6.87 | Evaluation of Biodistribution of Sulforaphane after Administration of Oral Broccoli Sprout Extract in Melanoma Patients with Multiple Atypical Nevi. ( Beumer, JH; Butterfield, LH; Cassidy, PB; Christner, SM; Dietz, CM; Fahey, JW; Ferris, LK; Hahm, ER; Hughes, E; Kirkwood, JM; Leachman, SA; Lin, Y; Rao, UN; Rose, A; Sander, C; Singh, SV; Tahata, S; Tarhini, AA; Tawbi, H; Wilson, M; Zarour, HM, 2018) |
| "Sulforaphane (SFN) is an organosulfur compound extracted from cruciferous vegetables and has biological effects." | 5.72 | Sulforaphane induces cell differentiation, melanogenesis and also inhibit the proliferation of melanoma cells. ( Eom, YS; Kim, SJ; Shah, FH, 2022) |
| "Human melanoma is a highly aggressive incurable cancer due to intrinsic cellular resistance to apoptosis, reprogramming, proliferation and survival during tumour progression." | 5.48 | Antitumor activity and expression profiles of genes induced by sulforaphane in human melanoma cells. ( Arcidiacono, P; Bottoni, U; Calvieri, S; Crisanti, A; Kuligina, E; Pistilli, A; Ragonese, F; Rende, M; Spaccapelo, R; Stabile, A, 2018) |
| "Melanoma is a severe form of cancer, resistant to conventional therapies." | 5.48 | Anticarcinogenic activities of sulforaphane are influenced by Nerve Growth Factor in human melanoma A375 cells. ( Arcidiacono, P; Bottoni, U; Calvieri, S; Crisanti, A; Pistilli, A; Ragonese, F; Rende, M; Spaccapelo, R; Stabile, AM, 2018) |
| "Melanoma is a metastatic cancer associated with poor survival." | 5.43 | The Ezh2 polycomb group protein drives an aggressive phenotype in melanoma cancer stem cells and is a target of diet derived sulforaphane. ( Adhikary, G; Eckert, RL; Fisher, ML; Grun, D; Kaetzel, DM, 2016) |
| "Sulforaphane (SF) is a promising isothiocyanate compound occurring in cruciferous plants with reported antiproliferative and proapoptotic activity in several tumor cell lines including melanoma." | 5.40 | Sulforaphane-induced apoptosis involves p53 and p38 in melanoma cells. ( Cervinka, M; Rudolf, E; Rudolf, K, 2014) |
| "We have utilised an in vitro model of malignant melanoma [consisting of human (A375, Hs294T, VMM1) and murine (B16F-10) melanoma cell lines as well as a non-melanoma (A431) and a non-tumorigenic immortalised keratinocyte (HaCaT) cell line] exposed to sulforaphane or iberin." | 4.02 | Sulforaphane and iberin are potent epigenetic modulators of histone acetylation and methylation in malignant melanoma. ( Franco, R; Mitsiogianni, M; Panayiotidis, MI; Pappa, A; Trafalis, DT; Zoumpourlis, V, 2021) |
| "Atypical nevi were photographed on days 1 and 28, and plasma and nevus samples were taken on days 1, 2, and 28." | 2.87 | Evaluation of Biodistribution of Sulforaphane after Administration of Oral Broccoli Sprout Extract in Melanoma Patients with Multiple Atypical Nevi. ( Beumer, JH; Butterfield, LH; Cassidy, PB; Christner, SM; Dietz, CM; Fahey, JW; Ferris, LK; Hahm, ER; Hughes, E; Kirkwood, JM; Leachman, SA; Lin, Y; Rao, UN; Rose, A; Sander, C; Singh, SV; Tahata, S; Tarhini, AA; Tawbi, H; Wilson, M; Zarour, HM, 2018) |
| "Melanoma is less common among all other types of skin cancers but causes higher mortality." | 2.58 | Epigenetics of skin cancer: Interventions by selected bioactive phytochemicals. ( Meeran, SM; Penta, D; Somashekar, BS, 2018) |
| "Sulforaphane (SFN) is an organosulfur compound extracted from cruciferous vegetables and has biological effects." | 1.72 | Sulforaphane induces cell differentiation, melanogenesis and also inhibit the proliferation of melanoma cells. ( Eom, YS; Kim, SJ; Shah, FH, 2022) |
| "Human melanoma is a highly aggressive incurable cancer due to intrinsic cellular resistance to apoptosis, reprogramming, proliferation and survival during tumour progression." | 1.48 | Antitumor activity and expression profiles of genes induced by sulforaphane in human melanoma cells. ( Arcidiacono, P; Bottoni, U; Calvieri, S; Crisanti, A; Kuligina, E; Pistilli, A; Ragonese, F; Rende, M; Spaccapelo, R; Stabile, A, 2018) |
| "Melanoma is a severe form of cancer, resistant to conventional therapies." | 1.48 | Anticarcinogenic activities of sulforaphane are influenced by Nerve Growth Factor in human melanoma A375 cells. ( Arcidiacono, P; Bottoni, U; Calvieri, S; Crisanti, A; Pistilli, A; Ragonese, F; Rende, M; Spaccapelo, R; Stabile, AM, 2018) |
| "Melanoma is a metastatic cancer associated with poor survival." | 1.43 | The Ezh2 polycomb group protein drives an aggressive phenotype in melanoma cancer stem cells and is a target of diet derived sulforaphane. ( Adhikary, G; Eckert, RL; Fisher, ML; Grun, D; Kaetzel, DM, 2016) |
| "Sulforaphane (SF) is a promising isothiocyanate compound occurring in cruciferous plants with reported antiproliferative and proapoptotic activity in several tumor cell lines including melanoma." | 1.40 | Sulforaphane-induced apoptosis involves p53 and p38 in melanoma cells. ( Cervinka, M; Rudolf, E; Rudolf, K, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 6 (60.00) | 24.3611 |
| 2020's | 4 (40.00) | 2.80 |
| Authors | Studies |
|---|---|
| Yepes-Molina, L | 1 |
| Carvajal, M | 1 |
| Eom, YS | 1 |
| Shah, FH | 1 |
| Kim, SJ | 1 |
| Mitsiogianni, M | 1 |
| Trafalis, DT | 1 |
| Franco, R | 1 |
| Zoumpourlis, V | 1 |
| Pappa, A | 1 |
| Panayiotidis, MI | 1 |
| Serini, S | 1 |
| Guarino, R | 1 |
| Ottes Vasconcelos, R | 1 |
| Celleno, L | 1 |
| Calviello, G | 1 |
| Arcidiacono, P | 2 |
| Ragonese, F | 2 |
| Stabile, A | 1 |
| Pistilli, A | 2 |
| Kuligina, E | 1 |
| Rende, M | 2 |
| Bottoni, U | 2 |
| Calvieri, S | 2 |
| Crisanti, A | 2 |
| Spaccapelo, R | 2 |
| Penta, D | 1 |
| Somashekar, BS | 1 |
| Meeran, SM | 1 |
| Stabile, AM | 1 |
| Tahata, S | 1 |
| Singh, SV | 1 |
| Lin, Y | 1 |
| Hahm, ER | 1 |
| Beumer, JH | 1 |
| Christner, SM | 1 |
| Rao, UN | 1 |
| Sander, C | 1 |
| Tarhini, AA | 1 |
| Tawbi, H | 1 |
| Ferris, LK | 1 |
| Wilson, M | 1 |
| Rose, A | 1 |
| Dietz, CM | 1 |
| Hughes, E | 1 |
| Fahey, JW | 1 |
| Leachman, SA | 1 |
| Cassidy, PB | 1 |
| Butterfield, LH | 1 |
| Zarour, HM | 1 |
| Kirkwood, JM | 1 |
| Rudolf, K | 1 |
| Cervinka, M | 1 |
| Rudolf, E | 1 |
| Fisher, ML | 1 |
| Adhikary, G | 1 |
| Grun, D | 1 |
| Kaetzel, DM | 1 |
| Eckert, RL | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Role and Clinical Relevance of Nerve Growth Factor (NGF) and Its Receptors (TrKA and p75NTR) in Patients With Erectile Dysfunction and Diabetes With or Wothout Metabolic Syndrome[NCT03862547] | 40 participants (Anticipated) | Interventional | 2019-01-30 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for sulforaphane and Malignant Melanoma
| Article | Year |
|---|---|
Epigenetics of skin cancer: Interventions by selected bioactive phytochemicals.
Topics: Anticarcinogenic Agents; Catechin; DNA Methylation; Epigenesis, Genetic; Histones; Humans; Isothiocy | 2018 |
1 trial available for sulforaphane and Malignant Melanoma
| Article | Year |
|---|---|
Evaluation of Biodistribution of Sulforaphane after Administration of Oral Broccoli Sprout Extract in Melanoma Patients with Multiple Atypical Nevi.
Topics: Administration, Oral; Adult; Aged; Biomarkers, Tumor; Biopsy; Brassica; Capsules; Feasibility Studie | 2018 |
8 other studies available for sulforaphane and Malignant Melanoma
| Article | Year |
|---|---|
Nanoencapsulation of sulforaphane in broccoli membrane vesicles and their
Topics: Anticarcinogenic Agents; Aquaporin 3; Brassica; Cell Line, Tumor; Cell Proliferation; Dose-Response | 2021 |
Sulforaphane induces cell differentiation, melanogenesis and also inhibit the proliferation of melanoma cells.
Topics: Animals; Cell Differentiation; Cell Line, Tumor; Cell Proliferation; Isothiocyanates; Melanins; Mela | 2022 |
Sulforaphane and iberin are potent epigenetic modulators of histone acetylation and methylation in malignant melanoma.
Topics: Acetylation; Animals; Cell Line, Tumor; Epigenesis, Genetic; Histone Acetyltransferases; Histones; H | 2021 |
The Combination of Sulforaphane and Fernblock
Topics: Antineoplastic Agents; Antioxidants; Brassica; Cell Line, Tumor; Cell Movement; Humans; Inflammasome | 2020 |
Antitumor activity and expression profiles of genes induced by sulforaphane in human melanoma cells.
Topics: Anticarcinogenic Agents; Apoptosis; Brassicaceae; Cell Line, Tumor; Cell Survival; Gene Expression R | 2018 |
Anticarcinogenic activities of sulforaphane are influenced by Nerve Growth Factor in human melanoma A375 cells.
Topics: Anticarcinogenic Agents; Apoptosis; Caspase 3; Cell Cycle; Cell Line, Tumor; Cell Movement; Cell Sur | 2018 |
Sulforaphane-induced apoptosis involves p53 and p38 in melanoma cells.
Topics: Anticarcinogenic Agents; Apoptosis; Caspases; Cell Line, Tumor; Humans; Isothiocyanates; Melanoma; M | 2014 |
The Ezh2 polycomb group protein drives an aggressive phenotype in melanoma cancer stem cells and is a target of diet derived sulforaphane.
Topics: Animals; Anticarcinogenic Agents; Cell Movement; Enhancer of Zeste Homolog 2 Protein; Gene Knockdown | 2016 |