Page last updated: 2024-11-04

sulforaphane and Leucocythaemia

sulforaphane has been researched along with Leucocythaemia in 7 studies

sulforaphane: from Cardaria draba L.
sulforaphane : An isothiocyanate having a 4-(methylsulfinyl)butyl group attached to the nitrogen.

Research Excerpts

ExcerptRelevanceReference
"Sulforaphane (SFN) is an isothiocyanate, inducing cytotoxic effects in various human cancer cells, including leukemia cells through cell cycle arrest and apoptosis."7.83Sulforaphane promotes immune responses in a WEHI‑3‑induced leukemia mouse model through enhanced phagocytosis of macrophages and natural killer cell activities in vivo. ( Chen, YL; Chung, JG; Hsueh, SC; Lee, CH; Liao, NC; Lu, HF; Shih, YL; Wu, LY, 2016)
"Tanshinone IIA (Tan IIA) is a diterpene quinone extracted from the root of Salvia miltiorrhiza, a Chinese traditional herb."5.38Analysis of tanshinone IIA induced cellular apoptosis in leukemia cells by genome-wide expression profiling. ( Chen, S; Huang, L; Li, J; Liu, C; Meng, F; Wang, L; Wu, F; Xiao, B; Xu, Y; Yang, M; Ye, J, 2012)
"Sulforaphane (SFN) has been indicated for the prevention and suppression of tumorigenesis in solid tumors."5.38Sulforaphane potentiates the efficacy of imatinib against chronic leukemia cancer stem cells through enhanced abrogation of Wnt/β-catenin function. ( Kuo, CC; Lee, CM; Lin, LC; Wang, LS; Wu, AT; Wu, CH; Yang, WC; Yeh, CT; Yen, GC, 2012)
"Sulforaphane (SFN) is an isothiocyanate, inducing cytotoxic effects in various human cancer cells, including leukemia cells through cell cycle arrest and apoptosis."3.83Sulforaphane promotes immune responses in a WEHI‑3‑induced leukemia mouse model through enhanced phagocytosis of macrophages and natural killer cell activities in vivo. ( Chen, YL; Chung, JG; Hsueh, SC; Lee, CH; Liao, NC; Lu, HF; Shih, YL; Wu, LY, 2016)
"Although clearly effective in acute promyelocytic leukemia (APL), arsenic trioxide (ATO) demonstrates little clinical benefit as a single agent in the treatment of non-APL hematological malignancies."3.76Enhancement of arsenic trioxide cytotoxicity by dietary isothiocyanates in human leukemic cells via a reactive oxygen species-dependent mechanism. ( Bowling, B; Doudican, NA; Orlow, SJ, 2010)
"Tanshinone IIA (Tan IIA) is a diterpene quinone extracted from the root of Salvia miltiorrhiza, a Chinese traditional herb."1.38Analysis of tanshinone IIA induced cellular apoptosis in leukemia cells by genome-wide expression profiling. ( Chen, S; Huang, L; Li, J; Liu, C; Meng, F; Wang, L; Wu, F; Xiao, B; Xu, Y; Yang, M; Ye, J, 2012)
"Sulforaphane (SFN) has been indicated for the prevention and suppression of tumorigenesis in solid tumors."1.38Sulforaphane potentiates the efficacy of imatinib against chronic leukemia cancer stem cells through enhanced abrogation of Wnt/β-catenin function. ( Kuo, CC; Lee, CM; Lin, LC; Wang, LS; Wu, AT; Wu, CH; Yang, WC; Yeh, CT; Yen, GC, 2012)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's7 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Suppipat, K1
Lacorazza, HD1
Philbrook, NA1
Winn, LM1
Shih, YL1
Wu, LY1
Lee, CH1
Chen, YL1
Hsueh, SC1
Lu, HF1
Liao, NC1
Chung, JG1
Doudican, NA1
Bowling, B1
Orlow, SJ1
Sharma, R1
Ellis, B1
Sharma, A1
Liu, C1
Li, J1
Wang, L1
Wu, F1
Huang, L1
Xu, Y1
Ye, J1
Xiao, B1
Meng, F1
Chen, S1
Yang, M1
Lin, LC1
Yeh, CT1
Kuo, CC1
Lee, CM1
Yen, GC1
Wang, LS1
Wu, CH1
Yang, WC1
Wu, AT1

Reviews

1 review available for sulforaphane and Leucocythaemia

ArticleYear
From the Table to the Bedside: Can Food-Derived Sulforaphane be used as a Novel Agent to Treat Leukemia?
    Current cancer drug targets, 2014, Volume: 14, Issue:5

    Topics: Animals; Antineoplastic Agents; Food; Humans; Isothiocyanates; Leukemia; Sulfoxides

2014

Other Studies

6 other studies available for sulforaphane and Leucocythaemia

ArticleYear
Benzoquinone toxicity is not prevented by sulforaphane in CD-1 mouse fetal liver cells.
    Journal of applied toxicology : JAT, 2016, Volume: 36, Issue:8

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Antioxidants; Benzoquinones; Catalase; Cell Line; Deoxyguanosi

2016
Sulforaphane promotes immune responses in a WEHI‑3‑induced leukemia mouse model through enhanced phagocytosis of macrophages and natural killer cell activities in vivo.
    Molecular medicine reports, 2016, Volume: 13, Issue:5

    Topics: Animals; Cell Line, Tumor; Humans; Isothiocyanates; Killer Cells, Natural; Leukemia; Lymphocyte Acti

2016
Enhancement of arsenic trioxide cytotoxicity by dietary isothiocyanates in human leukemic cells via a reactive oxygen species-dependent mechanism.
    Leukemia research, 2010, Volume: 34, Issue:2

    Topics: Antineoplastic Combined Chemotherapy Protocols; Arsenic Trioxide; Arsenicals; Cell Death; Drug Syner

2010
Role of alpha class glutathione transferases (GSTs) in chemoprevention: GSTA1 and A4 overexpressing human leukemia (HL60) cells resist sulforaphane and curcumin induced toxicity.
    Phytotherapy research : PTR, 2011, Volume: 25, Issue:4

    Topics: Blotting, Western; Curcumin; Glutathione Transferase; HL-60 Cells; Humans; Isothiocyanates; Leukemia

2011
Analysis of tanshinone IIA induced cellular apoptosis in leukemia cells by genome-wide expression profiling.
    BMC complementary and alternative medicine, 2012, Jan-16, Volume: 12

    Topics: Abietanes; Antineoplastic Agents, Phytogenic; Apoptosis; Cell Line, Tumor; Chemokine CCL2; Dose-Resp

2012
Sulforaphane potentiates the efficacy of imatinib against chronic leukemia cancer stem cells through enhanced abrogation of Wnt/β-catenin function.
    Journal of agricultural and food chemistry, 2012, Jul-18, Volume: 60, Issue:28

    Topics: ADP-ribosyl Cyclase 1; Anticarcinogenic Agents; Antigens, CD34; Antineoplastic Agents; Apoptosis; Be

2012