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sulforaphane and Invasiveness, Neoplasm

sulforaphane has been researched along with Invasiveness, Neoplasm in 15 studies

sulforaphane: from Cardaria draba L.
sulforaphane : An isothiocyanate having a 4-(methylsulfinyl)butyl group attached to the nitrogen.

Research Excerpts

ExcerptRelevanceReference
"Here we uncovered the involved subcellular mechanisms that sulforaphane-cysteine (SFN-Cys) inhibited invasion in human glioblastoma (GBM)."7.96Sulforaphane-cysteine inhibited migration and invasion via enhancing mitophagosome fusion to lysosome in human glioblastoma cells. ( Hu, Y; Li, J; Wang, Y; Wu, S; Wu, W; Yan, Y; Zheng, Z; Zhou, Y, 2020)
"However, its effect on hepatocellular carcinoma remains largely unknown."5.43Sulforaphane inhibits TGF-β-induced epithelial-mesenchymal transition of hepatocellular carcinoma cells via the reactive oxygen species-dependent pathway. ( Deng, C; Han, J; Hou, B; Shen, L; Wu, H; Wu, J, 2016)
"Sulforaphane (SFN) was demonstrated to inhibit cell growth in a variety of tumors."5.40Sulforaphane inhibits invasion via activating ERK1/2 signaling in human glioblastoma U87MG and U373MG cells. ( Du, L; Li, C; Niu, J; Peng, X; Tian, H; Wu, W; Yang, G; Zhou, Y, 2014)
"Here we uncovered the involved subcellular mechanisms that sulforaphane-cysteine (SFN-Cys) inhibited invasion in human glioblastoma (GBM)."3.96Sulforaphane-cysteine inhibited migration and invasion via enhancing mitophagosome fusion to lysosome in human glioblastoma cells. ( Hu, Y; Li, J; Wang, Y; Wu, S; Wu, W; Yan, Y; Zheng, Z; Zhou, Y, 2020)
"Sulforaphane is a diet-derived cancer prevention agent that is effective in suppressing tumor growth in animal models of skin cancer."1.48Combination cisplatin and sulforaphane treatment reduces proliferation, invasion, and tumor formation in epidermal squamous cell carcinoma. ( Adhikary, G; Eckert, RL; George, N; Grun, D; Kerr, C, 2018)
"However, its effect on hepatocellular carcinoma remains largely unknown."1.43Sulforaphane inhibits TGF-β-induced epithelial-mesenchymal transition of hepatocellular carcinoma cells via the reactive oxygen species-dependent pathway. ( Deng, C; Han, J; Hou, B; Shen, L; Wu, H; Wu, J, 2016)
"Advanced prostate cancer has highly invasive potential, which may lead to metastasis associated with poor prognosis."1.42Sulforaphane inhibits invasion by phosphorylating ERK1/2 to regulate E-cadherin and CD44v6 in human prostate cancer DU145 cells. ( Geng, Y; Li, C; Peng, X; Tian, H; Wu, S; Wu, W; Yang, G; Zhou, Y, 2015)
"However, its antitumor effect in thyroid cancer remains largely unknown."1.42Sulforaphane inhibits thyroid cancer cell growth and invasiveness through the reactive oxygen species-dependent pathway. ( Guan, H; Hou, P; Ji, M; Li, H; Shi, B; Tian, Z; Wang, L; Yang, Q, 2015)
"Sulforaphane (SFN) was demonstrated to inhibit cell growth in a variety of tumors."1.40Sulforaphane inhibits invasion via activating ERK1/2 signaling in human glioblastoma U87MG and U373MG cells. ( Du, L; Li, C; Niu, J; Peng, X; Tian, H; Wu, W; Yang, G; Zhou, Y, 2014)
"Sulforaphane is a predominant isothiocyanate in Brassica oleracea, a family of cruciferous vegetables, and is known to be inversely related to the risk of various types of human carcinomas."1.37Sulforaphane inhibits oral carcinoma cell migration and invasion in vitro. ( Jee, HG; Kim, JB; Lee, KE; Shin, HK; Youn, YK, 2011)
"These results are not limited to breast cancer cells since the Nrf2 inducer SFN stabilized Nrf2 and inhibited RON expression in carcinoma cells from various tumor types."1.37Novel function of transcription factor Nrf2 as an inhibitor of RON tyrosine kinase receptor-mediated cancer cell invasion. ( Ammanamanchi, S; Freeman, JW; Krishnegowda, NK; Rogge, J; Thangasamy, A, 2011)

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's13 (86.67)24.3611
2020's2 (13.33)2.80

Authors

AuthorsStudies
Justin, S1
Rutz, J1
Maxeiner, S1
Chun, FK1
Juengel, E1
Blaheta, RA1
Zhou, Y4
Wang, Y1
Wu, S3
Yan, Y1
Hu, Y2
Zheng, Z1
Li, J1
Wu, W4
Kerr, C1
Adhikary, G2
Grun, D2
George, N1
Eckert, RL2
Saha, K1
Fisher, ML1
Hsu, YC1
Chang, SJ1
Wang, MY1
Chen, YL1
Huang, TY1
Li, C2
Peng, X2
Du, L1
Tian, H3
Yang, G3
Niu, J1
Geng, Y2
Wang, L1
Tian, Z1
Yang, Q1
Li, H1
Guan, H1
Shi, B1
Hou, P1
Ji, M1
Lee, CS1
Cho, HJ1
Jeong, YJ1
Shin, JM1
Park, KK1
Park, YY1
Bae, YS1
Chung, IK1
Kim, M1
Kim, CH1
Jin, F1
Chang, HW1
Chang, YC1
Wu, J1
Han, J1
Hou, B1
Deng, C1
Wu, H1
Shen, L1
Rizzo, VL1
Levine, CB1
Wakshlag, JJ1
Lin, K1
Bryant, CS1
Kumar, S1
Chamala, S1
Shah, J1
Pal, J1
Haider, M1
Seward, S1
Qazi, AM1
Morris, R1
Semaan, A1
Shammas, MA1
Steffes, C1
Potti, RB1
Prasad, M1
Weaver, DW1
Batchu, RB1
Jee, HG1
Lee, KE1
Kim, JB1
Shin, HK1
Youn, YK1
Thangasamy, A1
Rogge, J1
Krishnegowda, NK1
Freeman, JW1
Ammanamanchi, S1

Other Studies

15 other studies available for sulforaphane and Invasiveness, Neoplasm

ArticleYear
Bladder Cancer Metastasis Induced by Chronic Everolimus Application Can Be Counteracted by Sulforaphane In Vitro.
    International journal of molecular sciences, 2020, Aug-04, Volume: 21, Issue:15

    Topics: Cell Adhesion; Cell Line, Tumor; Cell Proliferation; Everolimus; Gene Expression Regulation, Neoplas

2020
Sulforaphane-cysteine inhibited migration and invasion via enhancing mitophagosome fusion to lysosome in human glioblastoma cells.
    Cell death & disease, 2020, 10-01, Volume: 11, Issue:9

    Topics: Cell Line, Tumor; Cell Movement; Cysteine; Glioblastoma; Humans; Isothiocyanates; Lysosomes; Neoplas

2020
Combination cisplatin and sulforaphane treatment reduces proliferation, invasion, and tumor formation in epidermal squamous cell carcinoma.
    Molecular carcinogenesis, 2018, Volume: 57, Issue:1

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Carcinoma, Squamous Cell; Cell L

2018
Sulforaphane suppresses PRMT5/MEP50 function in epidermal squamous cell carcinoma leading to reduced tumor formation.
    Carcinogenesis, 2017, 08-01, Volume: 38, Issue:8

    Topics: Adaptor Proteins, Signal Transducing; Animals; Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Move

2017
Growth inhibition and apoptosis of neuroblastoma cells through ROS-independent MEK/ERK activation by sulforaphane.
    Cell biochemistry and biophysics, 2013, Volume: 66, Issue:3

    Topics: Anticarcinogenic Agents; Apoptosis; Carcinogenesis; Caspase 3; Caspase 9; Cell Line, Tumor; Cell Mov

2013
Sulforaphane inhibits invasion via activating ERK1/2 signaling in human glioblastoma U87MG and U373MG cells.
    PloS one, 2014, Volume: 9, Issue:2

    Topics: Anticarcinogenic Agents; Blotting, Western; Cell Line, Tumor; Cell Movement; Cell Survival; Dose-Res

2014
Sulforaphane inhibits invasion by phosphorylating ERK1/2 to regulate E-cadherin and CD44v6 in human prostate cancer DU145 cells.
    Oncology reports, 2015, Volume: 34, Issue:3

    Topics: Cadherins; Cell Line, Tumor; Gene Expression Regulation, Neoplastic; Humans; Hyaluronan Receptors; I

2015
Sulforaphane inhibits thyroid cancer cell growth and invasiveness through the reactive oxygen species-dependent pathway.
    Oncotarget, 2015, Sep-22, Volume: 6, Issue:28

    Topics: Animals; Anticarcinogenic Agents; Apoptosis; Apoptosis Regulatory Proteins; Blotting, Western; Cell

2015
Isothiocyanates inhibit the invasion and migration of C6 glioma cells by blocking FAK/JNK-mediated MMP-9 expression.
    Oncology reports, 2015, Volume: 34, Issue:6

    Topics: Cell Line, Tumor; Cell Movement; Extracellular Matrix; Focal Adhesion Kinase 1; Gene Expression Regu

2015
Sulforaphane inhibits TGF-β-induced epithelial-mesenchymal transition of hepatocellular carcinoma cells via the reactive oxygen species-dependent pathway.
    Oncology reports, 2016, Volume: 35, Issue:5

    Topics: Animals; Antineoplastic Agents; Apoptosis; Carcinoma, Hepatocellular; Cell Movement; Cell Shape; Epi

2016
The effects of sulforaphane on canine osteosarcoma proliferation and invasion.
    Veterinary and comparative oncology, 2017, Volume: 15, Issue:3

    Topics: Animals; Antibiotics, Antineoplastic; Anticarcinogenic Agents; Apoptosis; Bone Neoplasms; Cell Line,

2017
Sulforaphane-cysteine suppresses invasion via downregulation of galectin-1 in human prostate cancer DU145 and PC3 cells.
    Oncology reports, 2016, Volume: 36, Issue:3

    Topics: Anticarcinogenic Agents; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cysteine; Down-Regulat

2016
Sulforaphane induces cell cycle arrest by protecting RB-E2F-1 complex in epithelial ovarian cancer cells.
    Molecular cancer, 2010, Mar-02, Volume: 9

    Topics: Apoptosis; Cell Cycle; Cell Cycle Proteins; Cell Line, Tumor; Cell Movement; Cell Proliferation; DNA

2010
Sulforaphane inhibits oral carcinoma cell migration and invasion in vitro.
    Phytotherapy research : PTR, 2011, Volume: 25, Issue:11

    Topics: Cell Line, Tumor; Cell Movement; Gene Expression Regulation, Neoplastic; Humans; Isothiocyanates; Ma

2011
Novel function of transcription factor Nrf2 as an inhibitor of RON tyrosine kinase receptor-mediated cancer cell invasion.
    The Journal of biological chemistry, 2011, Sep-16, Volume: 286, Issue:37

    Topics: Anticarcinogenic Agents; Breast Neoplasms; Cell Line, Tumor; Female; Gene Expression Regulation, Enz

2011