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sulforaphane and Experimental Mammary Neoplasms

sulforaphane has been researched along with Experimental Mammary Neoplasms in 8 studies

sulforaphane: from Cardaria draba L.
sulforaphane : An isothiocyanate having a 4-(methylsulfinyl)butyl group attached to the nitrogen.

Research Excerpts

ExcerptRelevanceReference
"Sulforaphane (1-5 micromol/L) decreased aldehyde dehydrogenase-positive cell population by 65% to 80% in human breast cancer cells (P < 0."7.76Sulforaphane, a dietary component of broccoli/broccoli sprouts, inhibits breast cancer stem cells. ( Clouthier, SG; Korkaya, H; Lee, HF; Li, Y; Liu, S; Newman, B; Schwartz, SJ; Sun, D; Wicha, MS; Yu, Y; Zhang, T, 2010)
" Results of studies in a rat orthotopic breast cancer model indicated that SFN enhanced the efficacy of DOX in regression of tumor growth, and that the DOX dosage required to treat the tumor could be reduced when SFN was administered concomitantly."5.48Sulforaphane potentiates anticancer effects of doxorubicin and attenuates its cardiotoxicity in a breast cancer model. ( Awasthi, S; Beneš, H; Boerma, M; Bose, C; Hauer-Jensen, M; Sharma, R; Singh, SP, 2018)
"Sulforaphane (1-5 micromol/L) decreased aldehyde dehydrogenase-positive cell population by 65% to 80% in human breast cancer cells (P < 0."3.76Sulforaphane, a dietary component of broccoli/broccoli sprouts, inhibits breast cancer stem cells. ( Clouthier, SG; Korkaya, H; Lee, HF; Li, Y; Liu, S; Newman, B; Schwartz, SJ; Sun, D; Wicha, MS; Yu, Y; Zhang, T, 2010)
"Sulforaphane (SFN) is an isothiocyanate derived from broccoli that is currently under evaluation in multiple clinical trials for prevention of several diseases, including cancer."1.56Sulforaphane Diminishes the Formation of Mammary Tumors in Rats Exposed to 17β-Estradiol. ( Chartoumpekis, DV; Fazzari, M; Kensler, TW; Liao, Y; Michalopoulos, GK; Oesterreich, S; Palliyaguru, DL; Skoko, JJ; Wendell, SG; Yang, L, 2020)
"Moreover, in an orthotopic breast cancer model, the nanoparticles achieved a significantly higher tumor accumulation and exhibited a more powerful antitumor activity."1.51Sulforaphane Mediates Glutathione Depletion via Polymeric Nanoparticles to Restore Cisplatin Chemosensitivity. ( Bao, Y; Han, X; Li, Y; Min, H; Nie, G; Qi, S; Qi, Y; Shi, J; Xu, Y; Zhang, Y; Zhao, X, 2019)
" Results of studies in a rat orthotopic breast cancer model indicated that SFN enhanced the efficacy of DOX in regression of tumor growth, and that the DOX dosage required to treat the tumor could be reduced when SFN was administered concomitantly."1.48Sulforaphane potentiates anticancer effects of doxorubicin and attenuates its cardiotoxicity in a breast cancer model. ( Awasthi, S; Beneš, H; Boerma, M; Bose, C; Hauer-Jensen, M; Sharma, R; Singh, SP, 2018)
"05) reduced PCNA and elevated PARP fragmentation in samples from animals dosed with SUL."1.32Sulforaphane: a naturally occurring mammary carcinoma mitotic inhibitor, which disrupts tubulin polymerization. ( Jackson, SJ; Singletary, KW, 2004)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (25.00)18.2507
2000's2 (25.00)29.6817
2010's3 (37.50)24.3611
2020's1 (12.50)2.80

Authors

AuthorsStudies
Jang, DS1
Park, EJ1
Kang, YH1
Hawthorne, ME1
Vigo, JS1
Graham, JG1
Cabieses, F1
Fong, HH1
Mehta, RG2
Pezzuto, JM2
Kinghorn, AD1
Xu, Y1
Han, X1
Li, Y2
Min, H1
Zhao, X1
Zhang, Y2
Qi, Y1
Shi, J1
Qi, S1
Bao, Y1
Nie, G1
Palliyaguru, DL1
Yang, L1
Chartoumpekis, DV1
Wendell, SG1
Fazzari, M1
Skoko, JJ1
Liao, Y1
Oesterreich, S1
Michalopoulos, GK1
Kensler, TW2
Bose, C1
Awasthi, S1
Sharma, R1
Beneš, H1
Hauer-Jensen, M1
Boerma, M1
Singh, SP1
Zhang, T1
Korkaya, H1
Liu, S1
Lee, HF1
Newman, B1
Yu, Y1
Clouthier, SG1
Schwartz, SJ1
Wicha, MS1
Sun, D1
Jackson, SJ1
Singletary, KW1
Cho, CG1
Posner, GH1
Talalay, P1
Gerhäuser, C1
You, M1
Liu, J1
Moriarty, RM1
Hawthorne, M1
Moon, RC1

Other Studies

8 other studies available for sulforaphane and Experimental Mammary Neoplasms

ArticleYear
Potential cncer chemopreventive flavonoids from the stems of Tephrosia toxicaria.
    Journal of natural products, 2003, Volume: 66, Issue:9

    Topics: Animals; Anticarcinogenic Agents; Carcinoma, Hepatocellular; Chromones; Flavonoids; Heterocyclic Com

2003
Sulforaphane Mediates Glutathione Depletion via Polymeric Nanoparticles to Restore Cisplatin Chemosensitivity.
    ACS nano, 2019, 11-26, Volume: 13, Issue:11

    Topics: Animals; Antineoplastic Agents; Apoptosis; Breast Neoplasms; Cell Proliferation; Cell Survival; Cisp

2019
Sulforaphane Diminishes the Formation of Mammary Tumors in Rats Exposed to 17β-Estradiol.
    Nutrients, 2020, Jul-30, Volume: 12, Issue:8

    Topics: Animals; Anticarcinogenic Agents; Cell Proliferation; DNA Damage; Estradiol; Fatty Acids; Female; Is

2020
Sulforaphane potentiates anticancer effects of doxorubicin and attenuates its cardiotoxicity in a breast cancer model.
    PloS one, 2018, Volume: 13, Issue:3

    Topics: Animals; Anticarcinogenic Agents; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms;

2018
Sulforaphane, a dietary component of broccoli/broccoli sprouts, inhibits breast cancer stem cells.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2010, May-01, Volume: 16, Issue:9

    Topics: Aldehyde Dehydrogenase; Aldehyde Dehydrogenase 1 Family; Animals; Anticarcinogenic Agents; Apoptosis

2010
Sulforaphane: a naturally occurring mammary carcinoma mitotic inhibitor, which disrupts tubulin polymerization.
    Carcinogenesis, 2004, Volume: 25, Issue:2

    Topics: Animals; Anticarcinogenic Agents; Apoptosis; Caspases; CDC2 Protein Kinase; Cell Division; Chromatin

2004
Anticarcinogenic activities of sulforaphane and structurally related synthetic norbornyl isothiocyanates.
    Proceedings of the National Academy of Sciences of the United States of America, 1994, Apr-12, Volume: 91, Issue:8

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents; Female; Isothiocyanates; Mammary N

1994
Cancer chemopreventive potential of sulforamate, a novel analogue of sulforaphane that induces phase 2 drug-metabolizing enzymes.
    Cancer research, 1997, Jan-15, Volume: 57, Issue:2

    Topics: Animals; Anticarcinogenic Agents; Chloramphenicol O-Acetyltransferase; Enzyme Induction; Female; Gen

1997