sulforaphane has been researched along with Experimental Hepatoma in 7 studies
sulforaphane: from Cardaria draba L.
sulforaphane : An isothiocyanate having a 4-(methylsulfinyl)butyl group attached to the nitrogen.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Moreover, in an orthotopic breast cancer model, the nanoparticles achieved a significantly higher tumor accumulation and exhibited a more powerful antitumor activity." | 1.51 | Sulforaphane Mediates Glutathione Depletion via Polymeric Nanoparticles to Restore Cisplatin Chemosensitivity. ( Bao, Y; Han, X; Li, Y; Min, H; Nie, G; Qi, S; Qi, Y; Shi, J; Xu, Y; Zhang, Y; Zhao, X, 2019) |
| "Treatment of human hepatoma (HepG2) and murine hepatoma (Hepa1c1c7) cells with tert-butylhydroquinone (tBHQ) or sulforaphane (SUL), two potent phase II enzyme inducers, stimulated the activity of extracellular signal-regulated protein kinase 2 (ERK2) but not c-Jun N-terminal kinase 1." | 1.30 | Role of a mitogen-activated protein kinase pathway in the induction of phase II detoxifying enzymes by chemicals. ( Der, CJ; Kong, AN; Lei, W; Mandlekar, S; Weber, MJ; Wu, J; Yu, R, 1999) |
| "Sulforaphane is a monofunctional inducer, like other anticarcinogenic isothiocyanates, and induces phase II enzymes selectively without the induction of aryl hydrocarbon receptor-dependent cytochromes P-450 (phase I enzymes)." | 1.28 | A major inducer of anticarcinogenic protective enzymes from broccoli: isolation and elucidation of structure. ( Cho, CG; Posner, GH; Talalay, P; Zhang, Y, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (57.14) | 18.2507 |
| 2000's | 1 (14.29) | 29.6817 |
| 2010's | 2 (28.57) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Posner, GH | 2 |
| Cho, CG | 2 |
| Green, JV | 1 |
| Zhang, Y | 3 |
| Talalay, P | 2 |
| Chang, LC | 1 |
| Gerhäuser, C | 1 |
| Song, L | 1 |
| Farnsworth, NR | 1 |
| Pezzuto, JM | 1 |
| Kinghorn, AD | 1 |
| Xu, Y | 1 |
| Han, X | 1 |
| Li, Y | 1 |
| Min, H | 1 |
| Zhao, X | 1 |
| Qi, Y | 1 |
| Shi, J | 1 |
| Qi, S | 1 |
| Bao, Y | 1 |
| Nie, G | 1 |
| Yamaguchi, M | 1 |
| Moriarty, RM | 1 |
| Naithani, R | 1 |
| Kosmeder, J | 1 |
| Prakash, O | 1 |
| Yu, R | 1 |
| Lei, W | 1 |
| Mandlekar, S | 1 |
| Weber, MJ | 1 |
| Der, CJ | 1 |
| Wu, J | 1 |
| Kong, AN | 1 |
1 review available for sulforaphane and Experimental Hepatoma
| Article | Year |
|---|---|
The anti-apoptotic effect of regucalcin is mediated through multisignaling pathways.
Topics: Animals; Apoptosis; Apoptosis Regulatory Proteins; Calcium-Binding Proteins; Carcinoma, Hepatocellul | 2013 |
6 other studies available for sulforaphane and Experimental Hepatoma
| Article | Year |
|---|---|
Design and synthesis of bifunctional isothiocyanate analogs of sulforaphane: correlation between structure and potency as inducers of anticarcinogenic detoxication enzymes.
Topics: Animals; Anticarcinogenic Agents; Cyclization; Enzyme Induction; Female; Glutathione Transferase; Is | 1994 |
Activity-guided isolation of constituents of Tephrosia purpurea with the potential to induce the phase II enzyme, quinone reductase.
Topics: Animals; Enzyme Induction; India; Isothiocyanates; Liver Neoplasms, Experimental; Magnetic Resonance | 1997 |
Sulforaphane Mediates Glutathione Depletion via Polymeric Nanoparticles to Restore Cisplatin Chemosensitivity.
Topics: Animals; Antineoplastic Agents; Apoptosis; Breast Neoplasms; Cell Proliferation; Cell Survival; Cisp | 2019 |
Cancer chemopreventive activity of sulforamate derivatives.
Topics: Animals; Anticarcinogenic Agents; Carcinoma, Hepatocellular; Cell Survival; Isothiocyanates; Liver N | 2006 |
Role of a mitogen-activated protein kinase pathway in the induction of phase II detoxifying enzymes by chemicals.
Topics: Animals; Antineoplastic Agents; Carcinoma, Hepatocellular; Enzyme Induction; Enzyme Inhibitors; Flav | 1999 |
A major inducer of anticarcinogenic protective enzymes from broccoli: isolation and elucidation of structure.
Topics: Animals; Antineoplastic Agents; Brassica; Cell Line; Chromatography, High Pressure Liquid; Enzyme In | 1992 |