sulforaphane has been researched along with Colorectal Neoplasms in 14 studies
sulforaphane: from Cardaria draba L.
sulforaphane : An isothiocyanate having a 4-(methylsulfinyl)butyl group attached to the nitrogen.
Colorectal Neoplasms: Tumors or cancer of the COLON or the RECTUM or both. Risk factors for colorectal cancer include chronic ULCERATIVE COLITIS; FAMILIAL POLYPOSIS COLI; exposure to ASBESTOS; and irradiation of the CERVIX UTERI.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The objective of this study was to investigate, whether the plant-derived isothiocyanate Sulforaphane (SFN) enhances the antitumor activities of the chemotherapeutic agent oxaliplatin (Ox) in a cell culture model of colorectal cancer." | 7.77 | Sulforaphane potentiates oxaliplatin-induced cell growth inhibition in colorectal cancer cells via induction of different modes of cell death. ( Brüne, B; Kaminski, BM; Schumacher, M; Stein, J; Steinhilber, D; Ulrich, S; Weigert, A; Wenzel, U, 2011) |
| "The objective of this study was to elucidate molecular mechanisms behind the antitumor activities of the isothiocyanate sulforaphane (SFN) in colorectal cancer cells." | 7.76 | Isothiocyanate sulforaphane inhibits protooncogenic ornithine decarboxylase activity in colorectal cancer cells via induction of the TGF-β/Smad signaling pathway. ( Kaminski, BM; Loitsch, SM; Ochs, MJ; Reuter, KC; Stein, J; Steinhilber, D; Ulrich, S, 2010) |
| "The long pre‑cancerous state of colorectal cancer (CRC) provides an opportunity to prevent the occurrence and development of CRC." | 5.56 | Sulforaphane suppresses carcinogenesis of colorectal cancer through the ERK/Nrf2‑UDP glucuronosyltransferase 1A metabolic axis activation. ( Hao, Q; Li, C; Lin, YM; Liu, F; Sun, NX; Wang, M; Zhu, C; Zhu, WW, 2020) |
| "The objective of this study was to investigate, whether the plant-derived isothiocyanate Sulforaphane (SFN) enhances the antitumor activities of the chemotherapeutic agent oxaliplatin (Ox) in a cell culture model of colorectal cancer." | 3.77 | Sulforaphane potentiates oxaliplatin-induced cell growth inhibition in colorectal cancer cells via induction of different modes of cell death. ( Brüne, B; Kaminski, BM; Schumacher, M; Stein, J; Steinhilber, D; Ulrich, S; Weigert, A; Wenzel, U, 2011) |
| "The objective of this study was to elucidate molecular mechanisms behind the antitumor activities of the isothiocyanate sulforaphane (SFN) in colorectal cancer cells." | 3.76 | Isothiocyanate sulforaphane inhibits protooncogenic ornithine decarboxylase activity in colorectal cancer cells via induction of the TGF-β/Smad signaling pathway. ( Kaminski, BM; Loitsch, SM; Ochs, MJ; Reuter, KC; Stein, J; Steinhilber, D; Ulrich, S, 2010) |
| "Colorectal cancer is an increasingly significant cause of mortality whose risk is linked to diet and inversely correlated with cruciferous vegetable consumption." | 2.55 | The Role of MicroRNAs in the Chemopreventive Activity of Sulforaphane from Cruciferous Vegetables. ( Bao, Y; Dacosta, C, 2017) |
| "The long pre‑cancerous state of colorectal cancer (CRC) provides an opportunity to prevent the occurrence and development of CRC." | 1.56 | Sulforaphane suppresses carcinogenesis of colorectal cancer through the ERK/Nrf2‑UDP glucuronosyltransferase 1A metabolic axis activation. ( Hao, Q; Li, C; Lin, YM; Liu, F; Sun, NX; Wang, M; Zhu, C; Zhu, WW, 2020) |
| "Sporadic colorectal cancer (CRC) is a typical multifactorial disease." | 1.39 | Identification of microRNAs regulated by isothiocyanates and association of polymorphisms inside their target sites with risk of sporadic colorectal cancer. ( Bienertova-Vasku, J; Bischofová, S; Brezkova, V; Hezova, R; Kovarikova, A; Sachlova, M; Sevcikova, S; Slaby, O; Svoboda, M; Vasku, A; Vyzula, R, 2013) |
| "Sulforaphane (SFN) is an isothiocyanate that is present abundantly in widely consumed cruciferous vegetables and has a particularly high content in broccoli and cauliflower." | 1.33 | Cancer chemoprevention of intestinal polyposis in ApcMin/+ mice by sulforaphane, a natural product derived from cruciferous vegetable. ( Chada, K; Chen, C; Hebbar, V; Hu, R; Jeong, WS; Khor, TO; Kong, AN; Reddy, B; Shen, G; Xu, C, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (7.14) | 29.6817 |
| 2010's | 9 (64.29) | 24.3611 |
| 2020's | 4 (28.57) | 2.80 |
| Authors | Studies |
|---|---|
| Xi, MY | 1 |
| Jia, JM | 1 |
| Sun, HP | 1 |
| Sun, ZY | 1 |
| Jiang, JW | 1 |
| Wang, YJ | 1 |
| Zhang, MY | 1 |
| Zhu, JF | 1 |
| Xu, LL | 1 |
| Jiang, ZY | 1 |
| Xue, X | 1 |
| Ye, M | 1 |
| Yang, X | 1 |
| Gao, Y | 1 |
| Tao, L | 1 |
| Guo, XK | 1 |
| Xu, XL | 1 |
| Guo, QL | 1 |
| Zhang, XJ | 1 |
| Hu, R | 2 |
| You, QD | 1 |
| Chen, Y | 3 |
| Wang, MH | 1 |
| Wu, JY | 1 |
| Zhu, JY | 1 |
| Xie, CF | 1 |
| Li, XT | 1 |
| Wu, JS | 1 |
| Geng, SS | 1 |
| Li, YD | 1 |
| Han, HY | 1 |
| Zhong, CY | 1 |
| Tang, L | 1 |
| Ye, X | 1 |
| Shan, E | 1 |
| Han, H | 1 |
| Zhong, C | 1 |
| Baralić, K | 1 |
| Živančević, K | 1 |
| Marić, Đ | 1 |
| Bozic, D | 1 |
| Buha Djordjevic, A | 1 |
| Antonijević Miljaković, E | 1 |
| Ćurčić, M | 1 |
| Bulat, Z | 1 |
| Antonijević, B | 1 |
| Đukić-Ćosić, D | 1 |
| Hao, Q | 1 |
| Wang, M | 1 |
| Sun, NX | 1 |
| Zhu, C | 1 |
| Lin, YM | 1 |
| Li, C | 1 |
| Liu, F | 1 |
| Zhu, WW | 1 |
| Dacosta, C | 1 |
| Bao, Y | 2 |
| Terasaki, M | 1 |
| Maeda, H | 1 |
| Miyashita, K | 1 |
| Mutoh, M | 1 |
| Rajendran, P | 1 |
| Johnson, G | 1 |
| Li, L | 1 |
| Chen, YS | 1 |
| Dashwood, M | 1 |
| Nguyen, N | 1 |
| Ulusan, A | 1 |
| Ertem, F | 1 |
| Zhang, M | 1 |
| Li, J | 1 |
| Sun, D | 1 |
| Huang, Y | 1 |
| Wang, S | 1 |
| Leung, HC | 1 |
| Lieberman, D | 1 |
| Beaver, L | 1 |
| Ho, E | 1 |
| Bedford, M | 1 |
| Chang, K | 1 |
| Vilar, E | 1 |
| Dashwood, R | 1 |
| Slaby, O | 1 |
| Sachlova, M | 1 |
| Brezkova, V | 1 |
| Hezova, R | 1 |
| Kovarikova, A | 1 |
| Bischofová, S | 1 |
| Sevcikova, S | 1 |
| Bienertova-Vasku, J | 1 |
| Vasku, A | 1 |
| Svoboda, M | 1 |
| Vyzula, R | 1 |
| Holzner, S | 1 |
| Senfter, D | 1 |
| Stadler, S | 1 |
| Staribacher, A | 1 |
| Nguyen, CH | 1 |
| Gaggl, A | 1 |
| Geleff, S | 1 |
| Huttary, N | 1 |
| Krieger, S | 1 |
| Jäger, W | 1 |
| Dolznig, H | 1 |
| Mader, RM | 1 |
| Krupitza, G | 1 |
| Kaminski, BM | 2 |
| Loitsch, SM | 1 |
| Ochs, MJ | 1 |
| Reuter, KC | 1 |
| Steinhilber, D | 2 |
| Stein, J | 2 |
| Ulrich, S | 2 |
| Weigert, A | 1 |
| Brüne, B | 1 |
| Schumacher, M | 1 |
| Wenzel, U | 1 |
| Barrera, LN | 1 |
| Johnson, IT | 1 |
| Cassidy, A | 1 |
| Belshaw, NJ | 1 |
| Khor, TO | 1 |
| Shen, G | 1 |
| Jeong, WS | 1 |
| Hebbar, V | 1 |
| Chen, C | 1 |
| Xu, C | 1 |
| Reddy, B | 1 |
| Chada, K | 1 |
| Kong, AN | 1 |
1 review available for sulforaphane and Colorectal Neoplasms
| Article | Year |
|---|---|
The Role of MicroRNAs in the Chemopreventive Activity of Sulforaphane from Cruciferous Vegetables.
Topics: Anticarcinogenic Agents; Brassicaceae; Colorectal Neoplasms; Diet; Humans; Isothiocyanates; MicroRNA | 2017 |
13 other studies available for sulforaphane and Colorectal Neoplasms
| Article | Year |
|---|---|
3-aroylmethylene-2,3,6,7-tetrahydro-1H-pyrazino[2,1-a]isoquinolin-4(11bH)-ones as potent Nrf2/ARE inducers in human cancer cells and AOM-DSS treated mice.
Topics: Active Transport, Cell Nucleus; Adenoma; Animals; Antineoplastic Agents; Antioxidant Response Elemen | 2013 |
ΔNp63α mediates sulforaphane suppressed colorectal cancer stem cell properties through transcriptional regulation of Nanog/Oct4/Sox2.
Topics: Cell Line, Tumor; Colorectal Neoplasms; Humans; Isothiocyanates; Nanog Homeobox Protein; Neoplastic | 2022 |
Regulation of ZO-1 on β-catenin mediates sulforaphane suppressed colorectal cancer stem cell properties in colorectal cancer.
Topics: beta Catenin; Cell Line, Tumor; Cell Proliferation; Colorectal Neoplasms; Gene Expression Regulation | 2022 |
Testing sulforaphane as a strategy against toxic chemicals of public health concern by toxicogenomic data analysis: Friend or foe at the gene level - Colorectal carcinoma case study.
Topics: Aldehyde Dehydrogenase, Mitochondrial; Benzhydryl Compounds; Colorectal Neoplasms; Humans; Isothiocy | 2023 |
Sulforaphane suppresses carcinogenesis of colorectal cancer through the ERK/Nrf2‑UDP glucuronosyltransferase 1A metabolic axis activation.
Topics: Anticarcinogenic Agents; Antioxidants; Apoptosis; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Pro | 2020 |
Induction of Anoikis in Human Colorectal Cancer Cells by Fucoxanthinol.
Topics: Allyl Compounds; Anoikis; Antineoplastic Agents, Phytogenic; beta Carotene; Cell Line, Tumor; Cell P | 2017 |
Acetylation of CCAR2 Establishes a BET/BRD9 Acetyl Switch in Response to Combined Deacetylase and Bromodomain Inhibition.
Topics: Acetylation; Adaptor Proteins, Signal Transducing; Animals; Antineoplastic Combined Chemotherapy Pro | 2019 |
Identification of microRNAs regulated by isothiocyanates and association of polymorphisms inside their target sites with risk of sporadic colorectal cancer.
Topics: 3' Untranslated Regions; Aged; Binding Sites; Case-Control Studies; Cell Line; Colorectal Neoplasms; | 2013 |
Colorectal cancer cell-derived microRNA200 modulates the resistance of adjacent blood endothelial barriers in vitro.
Topics: Benzamides; Cell Line, Tumor; Cell Movement; Coculture Techniques; Colorectal Neoplasms; Endothelial | 2016 |
Isothiocyanate sulforaphane inhibits protooncogenic ornithine decarboxylase activity in colorectal cancer cells via induction of the TGF-β/Smad signaling pathway.
Topics: Anticarcinogenic Agents; Caco-2 Cells; Cell Proliferation; Colorectal Neoplasms; DNA-Binding Protein | 2010 |
Sulforaphane potentiates oxaliplatin-induced cell growth inhibition in colorectal cancer cells via induction of different modes of cell death.
Topics: Antineoplastic Agents; Apoptosis; Caco-2 Cells; Cell Proliferation; Colorectal Neoplasms; Dose-Respo | 2011 |
Colorectal cancer cells Caco-2 and HCT116 resist epigenetic effects of isothiocyanates and selenium in vitro.
Topics: Anticarcinogenic Agents; Antineoplastic Agents, Phytogenic; Antioxidants; Caco-2 Cells; Cell Prolife | 2013 |
Cancer chemoprevention of intestinal polyposis in ApcMin/+ mice by sulforaphane, a natural product derived from cruciferous vegetable.
Topics: Adenoma; Animals; Anticarcinogenic Agents; Cell Proliferation; Codon, Nonsense; Colorectal Neoplasms | 2006 |