Page last updated: 2024-11-04

sulforaphane and Colitis

sulforaphane has been researched along with Colitis in 8 studies

sulforaphane: from Cardaria draba L.
sulforaphane : An isothiocyanate having a 4-(methylsulfinyl)butyl group attached to the nitrogen.

Colitis: Inflammation of the COLON section of the large intestine (INTESTINE, LARGE), usually with symptoms such as DIARRHEA (often with blood and mucus), ABDOMINAL PAIN, and FEVER.

Research Excerpts

ExcerptRelevanceReference
"The efficacy of the sulforaphane derivative JY4 was evaluated in acute and chronic mouse models of ulcerative colitis induced by dextran sodium sulfate."8.12Therapeutic effect of the sulforaphane derivative JY4 on ulcerative colitis through the NF-κB-p65 pathway. ( Bai, CG; Bai, WF; Sun, TY; Wang, TX; Yang, YF; Zhang, YR; Zhao, XJ, 2022)
"Chronic inflammation and selenium deficiency are considered as risk factors for colon cancer."7.78Glutathione peroxidase-2 and selenium decreased inflammation and tumors in a mouse model of inflammation-associated carcinogenesis whereas sulforaphane effects differed with selenium supply. ( Banning, A; Brauer, MN; Brigelius-Flohé, R; Chu, FF; Esworthy, RS; Florian, S; Iori, R; Kipp, AP; Krehl, S; Loewinger, M; Wessjohann, LA, 2012)
"The efficacy of the sulforaphane derivative JY4 was evaluated in acute and chronic mouse models of ulcerative colitis induced by dextran sodium sulfate."4.12Therapeutic effect of the sulforaphane derivative JY4 on ulcerative colitis through the NF-κB-p65 pathway. ( Bai, CG; Bai, WF; Sun, TY; Wang, TX; Yang, YF; Zhang, YR; Zhao, XJ, 2022)
"Chronic inflammation and selenium deficiency are considered as risk factors for colon cancer."3.78Glutathione peroxidase-2 and selenium decreased inflammation and tumors in a mouse model of inflammation-associated carcinogenesis whereas sulforaphane effects differed with selenium supply. ( Banning, A; Brauer, MN; Brigelius-Flohé, R; Chu, FF; Esworthy, RS; Florian, S; Iori, R; Kipp, AP; Krehl, S; Loewinger, M; Wessjohann, LA, 2012)
"Sulforaphane is a bioactive metabolite with anti-inflammatory activity and is derived from the glucosinolate glucoraphanin, which is highly abundant in broccoli sprouts."1.91A steamed broccoli sprout diet preparation that reduces colitis via the gut microbiota. ( Chen, GY; Eaton, KA; Ho, S; Holman, J; Li, Y; McKinstry, D; Mendoza-Castrejon, J; Sun, D; Trindade, BC; Wells, E; Wen, B; Yuan, H; Zhang, T, 2023)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's4 (50.00)24.3611
2020's4 (50.00)2.80

Authors

AuthorsStudies
Wei, LY1
Zhang, JK1
Zheng, L1
Chen, Y1
Zhao, XJ1
Zhang, YR1
Bai, WF1
Sun, TY1
Yang, YF1
Wang, TX1
Bai, CG1
Zhang, T1
Holman, J1
McKinstry, D1
Trindade, BC1
Eaton, KA1
Mendoza-Castrejon, J1
Ho, S1
Wells, E1
Yuan, H1
Wen, B1
Sun, D1
Chen, GY1
Li, Y1
Wu, J2
Guo, W2
Cui, S2
Tang, X2
Zhang, Q2
Lu, W2
Jin, Y2
Zhao, J2
Mao, B2
Chen, W2
Wang, Y1
Jeffery, EH1
Miller, MJ1
Wallig, MA1
Wu, Y1
Wagner, AE1
Will, O1
Sturm, C1
Lipinski, S1
Rosenstiel, P1
Rimbach, G1
Choi, K1
Chen, J1
Mitra, S1
Sarna, SK1
Krehl, S1
Loewinger, M1
Florian, S1
Kipp, AP1
Banning, A1
Wessjohann, LA1
Brauer, MN1
Iori, R1
Esworthy, RS1
Chu, FF1
Brigelius-Flohé, R1

Reviews

1 review available for sulforaphane and Colitis

ArticleYear
The functional role of sulforaphane in intestinal inflammation: a review.
    Food & function, 2022, Jan-24, Volume: 13, Issue:2

    Topics: Animals; Anti-Inflammatory Agents; Brassicaceae; Colitis; Gastrointestinal Microbiome; Humans; Infla

2022

Other Studies

7 other studies available for sulforaphane and Colitis

ArticleYear
Therapeutic effect of the sulforaphane derivative JY4 on ulcerative colitis through the NF-κB-p65 pathway.
    Inflammopharmacology, 2022, Volume: 30, Issue:5

    Topics: Animals; Anti-Inflammatory Agents; Colitis; Colitis, Ulcerative; Colon; Dextran Sulfate; Disease Mod

2022
A steamed broccoli sprout diet preparation that reduces colitis via the gut microbiota.
    The Journal of nutritional biochemistry, 2023, Volume: 112

    Topics: Brassica; Colitis; Diet; Gastrointestinal Microbiome; Glucosinolates; Isothiocyanates

2023
Broccoli seed extract rich in polysaccharides and glucoraphanin ameliorates DSS-induced colitis via intestinal barrier protection and gut microbiota modulation in mice.
    Journal of the science of food and agriculture, 2023, Mar-15, Volume: 103, Issue:4

    Topics: Animals; Anti-Inflammatory Agents; Brassica; Colitis; Colon; Dextran Sulfate; Disease Models, Animal

2023
Broccoli seed extract rich in polysaccharides and glucoraphanin ameliorates DSS-induced colitis via intestinal barrier protection and gut microbiota modulation in mice.
    Journal of the science of food and agriculture, 2023, Mar-15, Volume: 103, Issue:4

    Topics: Animals; Anti-Inflammatory Agents; Brassica; Colitis; Colon; Dextran Sulfate; Disease Models, Animal

2023
Broccoli seed extract rich in polysaccharides and glucoraphanin ameliorates DSS-induced colitis via intestinal barrier protection and gut microbiota modulation in mice.
    Journal of the science of food and agriculture, 2023, Mar-15, Volume: 103, Issue:4

    Topics: Animals; Anti-Inflammatory Agents; Brassica; Colitis; Colon; Dextran Sulfate; Disease Models, Animal

2023
Broccoli seed extract rich in polysaccharides and glucoraphanin ameliorates DSS-induced colitis via intestinal barrier protection and gut microbiota modulation in mice.
    Journal of the science of food and agriculture, 2023, Mar-15, Volume: 103, Issue:4

    Topics: Animals; Anti-Inflammatory Agents; Brassica; Colitis; Colon; Dextran Sulfate; Disease Models, Animal

2023
Lightly Cooked Broccoli Is as Effective as Raw Broccoli in Mitigating Dextran Sulfate Sodium-Induced Colitis in Mice.
    Nutrients, 2018, Jun-08, Volume: 10, Issue:6

    Topics: Animals; Brassica; Colitis; Colon; Cooking; Dextran Sulfate; Disease Models, Animal; Enzyme Stabilit

2018
DSS-induced acute colitis in C57BL/6 mice is mitigated by sulforaphane pre-treatment.
    The Journal of nutritional biochemistry, 2013, Volume: 24, Issue:12

    Topics: Animals; Biomarkers; Colitis; Dextran Sulfate; Isothiocyanates; Male; Mice; Mice, Inbred C57BL; NF-E

2013
Impaired integrity of DNA after recovery from inflammation causes persistent dysfunction of colonic smooth muscle.
    Gastroenterology, 2011, Volume: 141, Issue:4

    Topics: Acetylcholine; Animals; Calcium Channels, L-Type; Colitis; Colon; Disease Models, Animal; DNA Damage

2011
Glutathione peroxidase-2 and selenium decreased inflammation and tumors in a mouse model of inflammation-associated carcinogenesis whereas sulforaphane effects differed with selenium supply.
    Carcinogenesis, 2012, Volume: 33, Issue:3

    Topics: Animals; Apoptosis; Azoxymethane; Cell Transformation, Neoplastic; Colitis; Colon; Colonic Neoplasms

2012