Page last updated: 2024-11-04

sulforaphane and Cognitive Dysfunction

sulforaphane has been researched along with Cognitive Dysfunction in 6 studies

sulforaphane: from Cardaria draba L.
sulforaphane : An isothiocyanate having a 4-(methylsulfinyl)butyl group attached to the nitrogen.

Cognitive Dysfunction: Diminished or impaired mental and/or intellectual function.

Research Excerpts

ExcerptRelevanceReference
"Sulforaphane (SFN) is a hormetin that activates the antioxidant and anti-inflammatory responses."5.72Long-term sulforaphane-treatment restores redox homeostasis and prevents cognitive decline in middleaged female and male rats, but cannot revert previous damage in old animals. ( Gómez-González, B; Hernández-Arciga, U; Königsberg, M; Librado-Osorio, R; López-Cervantes, SP; López-Diazguerrero, NE; Luna-López, A; Salas-Venegas, V; Santín-Márquez, R; Toledo-Pérez, R, 2022)
" This study aims to test whether sulforaphane (Sfn), a natural activator of nuclear factor erythroid 2-related factor 2 (Nrf2), reduces the chronic ischemic injury and cognitive dysfunction after VCI."3.91Protective effects of sulforaphane in experimental vascular cognitive impairment: Contribution of the Nrf2 pathway. ( Gao, Y; Lei, X; Li, X; Mao, L; Sun, B; Sun, Y; Yang, T; Zhang, F; Zhang, W; Zhao, Y, 2019)
"Sulforaphane (SFN) is a hormetin that activates the antioxidant and anti-inflammatory responses."1.72Long-term sulforaphane-treatment restores redox homeostasis and prevents cognitive decline in middleaged female and male rats, but cannot revert previous damage in old animals. ( Gómez-González, B; Hernández-Arciga, U; Königsberg, M; Librado-Osorio, R; López-Cervantes, SP; López-Diazguerrero, NE; Luna-López, A; Salas-Venegas, V; Santín-Márquez, R; Toledo-Pérez, R, 2022)
"Sulforaphane (SFN) is a pharmacological activator of Nrf2 that provokes Nrf2-mediated intracellular defenses, including antioxidant and anti-inflammatory responses, under oxidative stress (OS) conditions."1.48Protective Effects of Sulforaphane on Cognitive Impairments and AD-like Lesions in Diabetic Mice are Associated with the Upregulation of Nrf2 Transcription Activity. ( Chen, J; Luo, C; Lv, A; Pu, D; Sun, Y; Xiao, Q; Zhao, K; Zhao, Y; Zhu, S, 2018)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's5 (83.33)24.3611
2020's1 (16.67)2.80

Authors

AuthorsStudies
Santín-Márquez, R1
Hernández-Arciga, U1
Salas-Venegas, V1
Toledo-Pérez, R1
López-Cervantes, SP1
Librado-Osorio, R1
Luna-López, A1
López-Diazguerrero, NE1
Gómez-González, B1
Königsberg, M1
Pauletti, A2
Terrone, G2
Shekh-Ahmad, T2
Salamone, A2
Ravizza, T2
Rizzi, M2
Pastore, A2
Pascente, R2
Liang, LP2
Villa, BR2
Balosso, S2
Abramov, AY2
van Vliet, EA2
Del Giudice, E2
Aronica, E2
Antoine, DJ1
Patel, M2
Walker, MC2
Vezzani, A2
Mao, L1
Yang, T1
Li, X1
Lei, X1
Sun, Y2
Zhao, Y2
Zhang, W1
Gao, Y1
Sun, B1
Zhang, F1
Pu, D1
Chen, J1
Lv, A1
Zhu, S1
Luo, C1
Zhao, K1
Xiao, Q1
Wang, G1
Fang, H1
Zhen, Y1
Xu, G1
Tian, J1
Zhang, Y1
Zhang, D1
Zhang, G1
Xu, J1
Zhang, Z1
Qiu, M1
Ma, Y1
Zhang, H1
Zhang, X1

Other Studies

6 other studies available for sulforaphane and Cognitive Dysfunction

ArticleYear
Long-term sulforaphane-treatment restores redox homeostasis and prevents cognitive decline in middleaged female and male rats, but cannot revert previous damage in old animals.
    Biogerontology, 2022, Volume: 23, Issue:5

    Topics: Animals; Antioxidants; Cognitive Dysfunction; Female; Homeostasis; Isothiocyanates; Male; Oxidation-

2022
Targeting oxidative stress improves disease outcomes in a rat model of acquired epilepsy.
    Brain : a journal of neurology, 2017, Jul-01, Volume: 140, Issue:7

    Topics: Acetylcysteine; Animals; Astrocytes; Biomarkers; Cognitive Dysfunction; Disease Models, Animal; Drug

2017
Protective effects of sulforaphane in experimental vascular cognitive impairment: Contribution of the Nrf2 pathway.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2019, Volume: 39, Issue:2

    Topics: Animals; Brain; Brain Ischemia; Cell Death; Chronic Disease; Claudin-5; Cognitive Dysfunction; Endot

2019
Protective Effects of Sulforaphane on Cognitive Impairments and AD-like Lesions in Diabetic Mice are Associated with the Upregulation of Nrf2 Transcription Activity.
    Neuroscience, 2018, 06-15, Volume: 381

    Topics: Alzheimer Disease; Animals; Antioxidants; Cognitive Dysfunction; Diabetes Mellitus, Experimental; Di

2018
Targeting oxidative stress improves disease outcomes in a rat model of acquired epilepsy.
    Brain : a journal of neurology, 2019, 07-01, Volume: 142, Issue:7

    Topics: Acetylcysteine; Animals; Astrocytes; Biomarkers; Case-Control Studies; Cell Count; Cognitive Dysfunc

2019
Sulforaphane Prevents Neuronal Apoptosis and Memory Impairment in Diabetic Rats.
    Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 2016, Volume: 39, Issue:3

    Topics: Animals; Anticarcinogenic Agents; Apoptosis; Brain-Derived Neurotrophic Factor; Caspase 3; Cognitive

2016