sulforaphane has been researched along with Cell Transformation, Neoplastic in 11 studies
sulforaphane: from Cardaria draba L.
sulforaphane : An isothiocyanate having a 4-(methylsulfinyl)butyl group attached to the nitrogen.
Cell Transformation, Neoplastic: Cell changes manifested by escape from control mechanisms, increased growth potential, alterations in the cell surface, karyotypic abnormalities, morphological and biochemical deviations from the norm, and other attributes conferring the ability to invade, metastasize, and kill.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Chronic inflammation and selenium deficiency are considered as risk factors for colon cancer." | 7.78 | Glutathione peroxidase-2 and selenium decreased inflammation and tumors in a mouse model of inflammation-associated carcinogenesis whereas sulforaphane effects differed with selenium supply. ( Banning, A; Brauer, MN; Brigelius-Flohé, R; Chu, FF; Esworthy, RS; Florian, S; Iori, R; Kipp, AP; Krehl, S; Loewinger, M; Wessjohann, LA, 2012) |
| "Chronic inflammation and selenium deficiency are considered as risk factors for colon cancer." | 3.78 | Glutathione peroxidase-2 and selenium decreased inflammation and tumors in a mouse model of inflammation-associated carcinogenesis whereas sulforaphane effects differed with selenium supply. ( Banning, A; Brauer, MN; Brigelius-Flohé, R; Chu, FF; Esworthy, RS; Florian, S; Iori, R; Kipp, AP; Krehl, S; Loewinger, M; Wessjohann, LA, 2012) |
| "Sulforaphane (SFN) is a natural, biologically active compound extracted from cruciferous vegetables such as broccoli and cabbage with anti-inflammatory and anti-cancer properties." | 1.37 | Chemopreventive role of sulforaphane by upholding the GSH redox cycle in pre- and post-initiation phases of experimental lung carcinogenesis. ( Gayathri, R; Gunassekaran, G; Murugan, S; Priya, DK; Sakthisekaran, D, 2011) |
| "Sulforaphane (SFN) is an isothiocyanate from broccoli that induces phase 2 detoxification enzymes." | 1.33 | Sulforaphane inhibits histone deacetylase in vivo and suppresses tumorigenesis in Apc-minus mice. ( Dashwood, RH; Dashwood, WM; Ho, E; Myzak, MC; Orner, GA, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 5 (45.45) | 29.6817 |
| 2010's | 6 (54.55) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zhang, YK | 1 |
| Wang, H | 1 |
| Guo, YW | 1 |
| Yue, Y | 1 |
| Li, Q | 1 |
| Xia, J | 1 |
| Yao, Y | 1 |
| Gong, DW | 1 |
| Shi, H | 1 |
| Zhou, Q | 1 |
| Su, ZY | 1 |
| Zhang, C | 1 |
| Lee, JH | 1 |
| Shu, L | 1 |
| Wu, TY | 1 |
| Khor, TO | 1 |
| Conney, AH | 1 |
| Lu, YP | 1 |
| Kong, AN | 1 |
| Johnson, GS | 1 |
| Li, J | 1 |
| Beaver, LM | 1 |
| Dashwood, WM | 2 |
| Sun, D | 1 |
| Rajendran, P | 1 |
| Williams, DE | 1 |
| Ho, E | 2 |
| Dashwood, RH | 2 |
| Anwar-Mohamed, A | 1 |
| El-Kadi, AO | 1 |
| Priya, DK | 1 |
| Gayathri, R | 1 |
| Gunassekaran, G | 1 |
| Murugan, S | 1 |
| Sakthisekaran, D | 1 |
| Krehl, S | 1 |
| Loewinger, M | 1 |
| Florian, S | 1 |
| Kipp, AP | 1 |
| Banning, A | 1 |
| Wessjohann, LA | 1 |
| Brauer, MN | 1 |
| Iori, R | 3 |
| Esworthy, RS | 1 |
| Chu, FF | 1 |
| Brigelius-Flohé, R | 1 |
| Fimognari, C | 2 |
| Nüsse, M | 2 |
| Berti, F | 2 |
| Cantelli-Forti, G | 2 |
| Hrelia, P | 2 |
| Kuroiwa, Y | 1 |
| Nishikawa, A | 1 |
| Kitamura, Y | 1 |
| Kanki, K | 1 |
| Ishii, Y | 1 |
| Umemura, T | 1 |
| Hirose, M | 1 |
| Myzak, MC | 1 |
| Orner, GA | 1 |
11 other studies available for sulforaphane and Cell Transformation, Neoplastic
| Article | Year |
|---|---|
Novel role of Snail 1 in promoting tumor neoangiogenesis.
Topics: Anticarcinogenic Agents; Antigens, CD34; Cell Transformation, Neoplastic; Endoglin; Endothelial Cell | 2019 |
Sulforaphane inhibits mammary adipogenesis by targeting adipose mesenchymal stem cells.
Topics: Adipocytes; Adipogenesis; Animals; Breast Neoplasms; Cell Communication; Cell Differentiation; Cell | 2013 |
Requirement and epigenetics reprogramming of Nrf2 in suppression of tumor promoter TPA-induced mouse skin cell transformation by sulforaphane.
Topics: Animals; Anticarcinogenic Agents; Carcinogens; Cell Transformation, Neoplastic; Cells, Cultured; Epi | 2014 |
A functional pseudogene, NMRAL2P, is regulated by Nrf2 and serves as a coactivator of NQO1 in sulforaphane-treated colon cancer cells.
Topics: Anticarcinogenic Agents; Cell Transformation, Neoplastic; Colon; Colonic Neoplasms; Gene Expression; | 2017 |
Sulforaphane induces CYP1A1 mRNA, protein, and catalytic activity levels via an AhR-dependent pathway in murine hepatoma Hepa 1c1c7 and human HepG2 cells.
Topics: Animals; Brassica; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Transformation, Neoplastic; Cyt | 2009 |
Chemopreventive role of sulforaphane by upholding the GSH redox cycle in pre- and post-initiation phases of experimental lung carcinogenesis.
Topics: Adenosine Triphosphatases; Animals; Anticarcinogenic Agents; Antioxidants; Benzo(a)pyrene; Body Weig | 2011 |
Glutathione peroxidase-2 and selenium decreased inflammation and tumors in a mouse model of inflammation-associated carcinogenesis whereas sulforaphane effects differed with selenium supply.
Topics: Animals; Apoptosis; Azoxymethane; Cell Transformation, Neoplastic; Colitis; Colon; Colonic Neoplasms | 2012 |
Sulforaphane modulates cell cycle and apoptosis in transformed and non-transformed human T lymphocytes.
Topics: Anticarcinogenic Agents; Apoptosis; Cell Cycle; Cell Transformation, Neoplastic; Humans; Isothiocyan | 2003 |
Isothiocyanates as novel cytotoxic and cytostatic agents: molecular pathway on human transformed and non-transformed cells.
Topics: Antineoplastic Agents; Apoptosis; Cell Cycle; Cell Transformation, Neoplastic; Humans; Isothiocyanat | 2004 |
Protective effects of benzyl isothiocyanate and sulforaphane but not resveratrol against initiation of pancreatic carcinogenesis in hamsters.
Topics: Adenocarcinoma; Animals; Antineoplastic Agents, Phytogenic; Carcinogenicity Tests; Carcinogens; Cell | 2006 |
Sulforaphane inhibits histone deacetylase in vivo and suppresses tumorigenesis in Apc-minus mice.
Topics: Acetylation; Administration, Oral; Animals; Cell Transformation, Neoplastic; Chromatin; Drug Screeni | 2006 |