sulforaphane has been researched along with Cardiac Toxicity in 5 studies
sulforaphane: from Cardaria draba L.
sulforaphane : An isothiocyanate having a 4-(methylsulfinyl)butyl group attached to the nitrogen.
| Excerpt | Relevance | Reference |
|---|---|---|
| " This study aimed to investigate the protective potential of sulforaphane (SF), nuclear factor E2 related factor (Nrf-2) activator, against CPZ-induced cardiotoxicity and hepatotoxicity." | 8.31 | Sulforaphane, an Nrf-2 Agonist, Modulates Oxidative Stress and Inflammation in a Rat Model of Cuprizone-Induced Cardiotoxicity and Hepatotoxicity. ( Ibrahim Fouad, G, 2023) |
| "Hexavalent chromium (Cr(vi)), the most toxic valence state of chromium, is widely present in industrial effluents and wastes." | 5.56 | Sulforaphane attenuates hexavalent chromium-induced cardiotoxicity ( Baiyun, R; Han, B; Li, S; Liu, Y; Lv, Y; Lv, Z; Wang, X; Xue, J; Yang, D; Zhang, Z, 2020) |
| " Results of studies in a rat orthotopic breast cancer model indicated that SFN enhanced the efficacy of DOX in regression of tumor growth, and that the DOX dosage required to treat the tumor could be reduced when SFN was administered concomitantly." | 5.48 | Sulforaphane potentiates anticancer effects of doxorubicin and attenuates its cardiotoxicity in a breast cancer model. ( Awasthi, S; Beneš, H; Boerma, M; Bose, C; Hauer-Jensen, M; Sharma, R; Singh, SP, 2018) |
| " This study aimed to investigate the protective potential of sulforaphane (SF), nuclear factor E2 related factor (Nrf-2) activator, against CPZ-induced cardiotoxicity and hepatotoxicity." | 4.31 | Sulforaphane, an Nrf-2 Agonist, Modulates Oxidative Stress and Inflammation in a Rat Model of Cuprizone-Induced Cardiotoxicity and Hepatotoxicity. ( Ibrahim Fouad, G, 2023) |
| "Hexavalent chromium (Cr(vi)), the most toxic valence state of chromium, is widely present in industrial effluents and wastes." | 1.56 | Sulforaphane attenuates hexavalent chromium-induced cardiotoxicity ( Baiyun, R; Han, B; Li, S; Liu, Y; Lv, Y; Lv, Z; Wang, X; Xue, J; Yang, D; Zhang, Z, 2020) |
| "Dose-dependent cardiotoxicity is the leading adverse reaction seen in cancer patients treated with doxorubicin." | 1.51 | Attenuation of doxorubicin-induced cardiotoxicity in a human in vitro cardiac model by the induction of the NRF-2 pathway. ( Bentley, RA; Colley, HE; Copple, IM; Cross, MJ; Lu, ZQ; Murdoch, C; Sharma, P; Tomlinson, L; Webb, SD, 2019) |
| " Results of studies in a rat orthotopic breast cancer model indicated that SFN enhanced the efficacy of DOX in regression of tumor growth, and that the DOX dosage required to treat the tumor could be reduced when SFN was administered concomitantly." | 1.48 | Sulforaphane potentiates anticancer effects of doxorubicin and attenuates its cardiotoxicity in a breast cancer model. ( Awasthi, S; Beneš, H; Boerma, M; Bose, C; Hauer-Jensen, M; Sharma, R; Singh, SP, 2018) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (60.00) | 24.3611 |
| 2020's | 2 (40.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ibrahim Fouad, G | 1 |
| Yang, D | 1 |
| Han, B | 1 |
| Baiyun, R | 1 |
| Lv, Z | 1 |
| Wang, X | 2 |
| Li, S | 1 |
| Lv, Y | 1 |
| Xue, J | 1 |
| Liu, Y | 1 |
| Zhang, Z | 1 |
| Bai, Y | 1 |
| Chen, Q | 1 |
| Sun, YP | 1 |
| Lv, L | 1 |
| Zhang, LP | 1 |
| Liu, JS | 1 |
| Zhao, S | 1 |
| Wang, XL | 1 |
| Bose, C | 1 |
| Awasthi, S | 1 |
| Sharma, R | 1 |
| Beneš, H | 1 |
| Hauer-Jensen, M | 1 |
| Boerma, M | 1 |
| Singh, SP | 1 |
| Tomlinson, L | 1 |
| Lu, ZQ | 1 |
| Bentley, RA | 1 |
| Colley, HE | 1 |
| Murdoch, C | 1 |
| Webb, SD | 1 |
| Cross, MJ | 1 |
| Copple, IM | 1 |
| Sharma, P | 1 |
5 other studies available for sulforaphane and Cardiac Toxicity
| Article | Year |
|---|---|
Sulforaphane, an Nrf-2 Agonist, Modulates Oxidative Stress and Inflammation in a Rat Model of Cuprizone-Induced Cardiotoxicity and Hepatotoxicity.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Cardiotoxicity; Catalase; Chemical and Drug Induced | 2023 |
Sulforaphane attenuates hexavalent chromium-induced cardiotoxicity
Topics: AMP-Activated Protein Kinases; Animals; Cardiotonic Agents; Cardiotoxicity; Chromium; Heart; Isothio | 2020 |
Sulforaphane protection against the development of doxorubicin-induced chronic heart failure is associated with Nrf2 Upregulation.
Topics: Animals; Cardiotoxicity; Cell Line; Chronic Disease; Collagen; Disease Models, Animal; Doxorubicin; | 2017 |
Sulforaphane potentiates anticancer effects of doxorubicin and attenuates its cardiotoxicity in a breast cancer model.
Topics: Animals; Anticarcinogenic Agents; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; | 2018 |
Attenuation of doxorubicin-induced cardiotoxicity in a human in vitro cardiac model by the induction of the NRF-2 pathway.
Topics: Antibiotics, Antineoplastic; Cardiotoxicity; Cell Survival; Dexrazoxane; Doxorubicin; Drug Synergism | 2019 |