sulforaphane has been researched along with Carcinoma, Non-Small Cell Lung in 14 studies
sulforaphane: from Cardaria draba L.
sulforaphane : An isothiocyanate having a 4-(methylsulfinyl)butyl group attached to the nitrogen.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Sulforaphane (SFN) has been shown to induce the production of reactive oxygen species (ROS) and inhibit epidermal growth factor receptor (EGFR)-mediated signaling in non-small-cell lung cancer (NSCLC)." | 1.51 | High levels of EGFR prevent sulforaphane-induced reactive oxygen species-mediated apoptosis in non-small-cell lung cancer cells. ( Chen, CC; Chen, CY; Huang, KY; Shih, YM; Wang, TH, 2019) |
| "Sulforaphane (SFN) was first isolated from broccoli sprout and it is present at high concentrations in plants belonging to the Cruciferae family." | 1.51 | Expression of cyclin B1, D1 and K in non‑small cell lung cancer H1299 cells following treatment with sulforaphane. ( Grzanka, A; Grzanka, D; Klimaszewska-Wiśniewska, A; Krajewski, A; Żuryń, A, 2019) |
| "Long treatment with paclitaxel (PTX) might increase resistance and side-effects causing a failure in cancer chemotherapy." | 1.48 | Sulforaphane metabolites reduce resistance to paclitaxel via microtubule disruption. ( Li, J; Wang, Y; Wu, W; Yan, Y; Zheng, Z; Zhou, Y, 2018) |
| "Phenethyl isothiocyanate (PEITC) is a more potent inducer of apoptosis than sulforaphane (SFN) in A549 cells, but SFN induces more ROS generation and oxidative damages than PEITC, suggesting that oxidative stress again is probably not a trigger for apoptosis in these cells." | 1.35 | Binding to protein by isothiocyanates: a potential mechanism for apoptosis induction in human non small lung cancer cells. ( Chung, FL; Mi, L, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (14.29) | 29.6817 |
| 2010's | 11 (78.57) | 24.3611 |
| 2020's | 1 (7.14) | 2.80 |
| Authors | Studies |
|---|---|
| Wang, X | 2 |
| Yu, C | 1 |
| Wang, C | 1 |
| Ma, Y | 1 |
| Wang, T | 1 |
| Li, Y | 1 |
| Huang, Z | 1 |
| Zhou, M | 1 |
| Sun, P | 1 |
| Zheng, J | 1 |
| Yang, S | 1 |
| Fan, Y | 1 |
| Xiang, R | 1 |
| Meng, W | 1 |
| Meng, J | 1 |
| Zhang, F | 1 |
| Jiang, H | 1 |
| Feng, X | 1 |
| Zhao, F | 1 |
| Wang, K | 1 |
| Wang, TH | 1 |
| Chen, CC | 1 |
| Huang, KY | 1 |
| Shih, YM | 1 |
| Chen, CY | 2 |
| Hu, Y | 2 |
| Zhou, Y | 3 |
| Yang, G | 1 |
| Wang, Y | 3 |
| Zheng, Z | 3 |
| Li, J | 2 |
| Yan, Y | 2 |
| Wu, W | 3 |
| Tsai, JY | 1 |
| Tsai, SH | 1 |
| Wu, CC | 1 |
| Żuryń, A | 2 |
| Krajewski, A | 2 |
| Klimaszewska-Wiśniewska, A | 2 |
| Grzanka, A | 1 |
| Grzanka, D | 2 |
| Lin, K | 1 |
| Ding, X | 1 |
| Yu, ZY | 1 |
| Chuang, YS | 1 |
| Huang, RM | 1 |
| Wang, TC | 1 |
| Litwiniec, A | 1 |
| Safiejko-Mroczka, B | 1 |
| Gagat, M | 1 |
| Gackowska, L | 1 |
| Wang, DX | 1 |
| Zou, YJ | 1 |
| Zhuang, XB | 1 |
| Chen, SX | 1 |
| Lin, Y | 1 |
| Li, WL | 1 |
| Lin, JJ | 1 |
| Lin, ZQ | 1 |
| Li, QQ | 1 |
| Xie, YK | 1 |
| Wu, Y | 1 |
| Li, LL | 1 |
| Liu, Y | 1 |
| Miao, XB | 1 |
| Liu, QZ | 1 |
| Yao, KT | 1 |
| Xiao, GH | 1 |
| Mi, L | 2 |
| Chung, FL | 2 |
| Govind, S | 1 |
| Hood, BL | 1 |
| Veenstra, TD | 1 |
| Conrads, TP | 1 |
| Saha, DT | 1 |
| Goldman, R | 1 |
14 other studies available for sulforaphane and Carcinoma, Non-Small Cell Lung
| Article | Year |
|---|---|
Novel cyclin-dependent kinase 9 (CDK9) inhibitor with suppression of cancer stemness activity against non-small-cell lung cancer.
Topics: Antineoplastic Agents; Apoptosis; Carcinoma, Non-Small-Cell Lung; Cell Proliferation; Cyclin-Depende | 2019 |
Sulforaphane overcomes T790M-mediated gefitinib resistance in vitro through epithelial-mesenchymal transition.
Topics: Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Proliferation; Drug Re | 2021 |
High levels of EGFR prevent sulforaphane-induced reactive oxygen species-mediated apoptosis in non-small-cell lung cancer cells.
Topics: Animals; Anticarcinogenic Agents; Antioxidants; Apoptosis; Carcinogenesis; Carcinoma, Non-Small-Cell | 2019 |
Sulforaphane-N-Acetyl-Cysteine inhibited autophagy leading to apoptosis via Hsp70-mediated microtubule disruption.
Topics: Acetylcysteine; Aged; Anticarcinogenic Agents; Apoptosis; Autophagy; Carcinoma, Non-Small-Cell Lung; | 2018 |
The chemopreventive isothiocyanate sulforaphane reduces anoikis resistance and anchorage-independent growth in non-small cell human lung cancer cells.
Topics: Anoikis; Anticarcinogenic Agents; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Humans; Isothioc | 2019 |
Sulforaphane metabolites reduce resistance to paclitaxel via microtubule disruption.
Topics: A549 Cells; Aged; Antineoplastic Agents; Apoptosis; Carcinoma, Non-Small-Cell Lung; Cell Proliferati | 2018 |
Expression of cyclin B1, D1 and K in non‑small cell lung cancer H1299 cells following treatment with sulforaphane.
Topics: Anticarcinogenic Agents; Apoptosis; Carcinoma, Non-Small-Cell Lung; Cell Cycle Checkpoints; Cell Div | 2019 |
Sulforaphane metabolites inhibit migration and invasion via microtubule-mediated Claudins dysfunction or inhibition of autolysosome formation in human non-small cell lung cancer cells.
Topics: A549 Cells; Antineoplastic Agents; Autophagosomes; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamo | 2019 |
Sulforaphane attenuates EGFR signaling in NSCLC cells.
Topics: Animals; Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; ErbB Receptors; Hu | 2015 |
The effect of sulforaphane on the cell cycle, apoptosis and expression of cyclin D1 and p21 in the A549 non-small cell lung cancer cell line.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Carcinoma, Non-Small-Cell Lung; Cell Cycle; Cell Line, | 2016 |
Sulforaphane suppresses EMT and metastasis in human lung cancer through miR-616-5p-mediated GSK3β/β-catenin signaling pathways.
Topics: Animals; beta Catenin; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Survival; Epithelial-M | 2017 |
Sulforaphane inhibits cancer stem-like cell properties and cisplatin resistance through miR-214-mediated downregulation of c-MYC in non-small cell lung cancer.
Topics: 3' Untranslated Regions; A549 Cells; Animals; Antineoplastic Agents; beta Catenin; Blotting, Western | 2017 |
Binding to protein by isothiocyanates: a potential mechanism for apoptosis induction in human non small lung cancer cells.
Topics: Apoptosis; Carcinoma, Non-Small-Cell Lung; Cysteine; DNA Damage; Humans; Isothiocyanates; Lung Neopl | 2008 |
The role of protein binding in induction of apoptosis by phenethyl isothiocyanate and sulforaphane in human non-small lung cancer cells.
Topics: Animals; Anticarcinogenic Agents; Apoptosis; Carcinoma, Non-Small-Cell Lung; Cattle; Cell Line, Tumo | 2007 |