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sulforaphane and Carcinoma, Epidermoid

sulforaphane has been researched along with Carcinoma, Epidermoid in 13 studies

sulforaphane: from Cardaria draba L.
sulforaphane : An isothiocyanate having a 4-(methylsulfinyl)butyl group attached to the nitrogen.

Research Excerpts

ExcerptRelevanceReference
"Sulforaphane appears to inhibit sCC progression by impacting its growth and invasion ability, and regulates miR-199a-5p/Sirt1 and CD44ICD signaling pathways, and may be utilized to develop a curative approach for sSCC."1.91Sulforaphane suppresses skin squamous cell carcinoma cells proliferation through miR-199a-5p/Sirt1/CD44ICD signaling pathway. ( Ai, P; Chen, SZ; Lei, SY; Zhang, Y, 2023)
"Sulforaphane (SFN) is a promising cancer prevention and treatment agent that strongly suppresses the cutaneous squamous cell carcinoma (CSCC) cell cancer phenotype."1.91Sulforaphane inhibits CD44v6/YAP1/TEAD signaling to suppress the cancer phenotype. ( Adhikary, G; Chen, X; Eckert, RL; Ma, E; Naselsky, W; Newland, JJ; Xu, W, 2023)
"Sulforaphane (SFN) is an important diet-derived cancer prevention agent that is known to possess a reactive isothiocyanate group and has potent anticancer activity."1.72Sulforaphane covalently interacts with the transglutaminase 2 cancer maintenance protein to alter its structure and suppress its activity. ( Adhikary, G; Eckert, RL; Gates, EWJ; Godoy-Ruiz, R; Keillor, JW; Lakowicz, JR; Puranik, P; Rorke, EA; Szmacinski, H; Weber, DJ, 2022)
"Sulforaphane is a diet-derived cancer prevention agent that is effective in suppressing tumor growth in animal models of skin cancer."1.48Combination cisplatin and sulforaphane treatment reduces proliferation, invasion, and tumor formation in epidermal squamous cell carcinoma. ( Adhikary, G; Eckert, RL; George, N; Grun, D; Kerr, C, 2018)
"Sulforaphane treatment resulted in a dose-dependent increase in the levels of tumor suppressive miR200c."1.46Sulforaphane targets cancer stemness and tumor initiating properties in oral squamous cell carcinomas via miR-200c induction. ( Liao, YW; Liu, CM; Lu, MY; Peng, CY; Tsai, ML; Yeh, JC; Yu, CC; Yu, CH, 2017)
"Sulforaphane is a naturally occurring compound found in broccoli and other cruciferous vegetables."1.37Radiosensitization of head and neck cancer cells by the phytochemical agent sulforaphane. ( Brunner, M; Czembirek, C; Eder-Czembirek, C; Fahim, T; Heiduschka, G; Kotowski, U; Schmidt, R; Thurnher, D, 2011)
"(R)L-sulforaphane (SF) is a compound that protects against erythema, but it can also induce DNA fragmentation that leads to cell death by apoptosis."1.35Effect of (R)L-sulforaphane on 5-aminolevulinic acid-mediated photodynamic therapy. ( Juzeniene, A; Mikolajewska, P; Moan, J, 2008)
"In this study, we found that oral squamous cell carcinomas (OSCCs) in Korean patients have a high level of COX-2 expression when compared with normal mucosa."1.35Sulforaphane enhances caspase-dependent apoptosis through inhibition of cyclooxygenase-2 expression in human oral squamous carcinoma cells and nude mouse xenograft model. ( Cho, NP; Cho, SD; Choi, IS; Choi, KH; Choi, SH; Han, HS; Jung, JY; Kim, HJ; Kong, G; Leem, DH; Moon, KS; Soh, Y, 2009)
"Sulforaphane is an isothiocyanate derived from cruciferous vegetables that has been linked to decreased risk of certain cancers."1.35Inhibition of activator protein-1 by sulforaphane involves interaction with cysteine in the cFos DNA-binding domain: implications for chemoprevention of UVB-induced skin cancer. ( Bowden, GT; Dickinson, SE; Melton, TF; Olson, ER; Saboda, K; Zhang, J, 2009)

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's4 (30.77)29.6817
2010's6 (46.15)24.3611
2020's3 (23.08)2.80

Authors

AuthorsStudies
Rorke, EA1
Adhikary, G4
Szmacinski, H1
Lakowicz, JR1
Weber, DJ1
Godoy-Ruiz, R1
Puranik, P1
Keillor, JW1
Gates, EWJ1
Eckert, RL4
Zhang, Y1
Ai, P1
Chen, SZ1
Lei, SY1
Chen, X1
Ma, E1
Newland, JJ1
Naselsky, W1
Xu, W1
Kerr, C1
Grun, D2
George, N1
Saha, K1
Fisher, ML1
Elkashty, OA1
Ashry, R1
Elghanam, GA1
Pham, HM1
Su, X1
Stegen, C1
Tran, SD1
Zheng, Z1
Lin, K1
Hu, Y1
Zhou, Y1
Ding, X1
Wang, Y1
Wu, W1
Liu, CM1
Peng, CY1
Liao, YW1
Lu, MY1
Tsai, ML1
Yeh, JC1
Yu, CH1
Yu, CC1
Mikolajewska, P1
Juzeniene, A1
Moan, J1
Cho, NP1
Han, HS1
Leem, DH1
Choi, IS1
Jung, JY1
Kim, HJ1
Moon, KS1
Choi, KH1
Soh, Y1
Kong, G1
Cho, SD1
Choi, SH1
Dickinson, SE1
Melton, TF1
Olson, ER1
Zhang, J1
Saboda, K1
Bowden, GT1
Kotowski, U1
Heiduschka, G1
Brunner, M1
Czembirek, C1
Eder-Czembirek, C1
Schmidt, R1
Fahim, T1
Thurnher, D1
Fang, MZ1
Chen, D1
Sun, Y1
Jin, Z1
Christman, JK1
Yang, CS1

Other Studies

13 other studies available for sulforaphane and Carcinoma, Epidermoid

ArticleYear
Sulforaphane covalently interacts with the transglutaminase 2 cancer maintenance protein to alter its structure and suppress its activity.
    Molecular carcinogenesis, 2022, Volume: 61, Issue:1

    Topics: Animals; Antineoplastic Agents; Binding Sites; Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Prol

2022
Sulforaphane suppresses skin squamous cell carcinoma cells proliferation through miR-199a-5p/Sirt1/CD44ICD signaling pathway.
    Immunopharmacology and immunotoxicology, 2023, Volume: 45, Issue:1

    Topics: Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Proliferation; Humans; MicroRNAs; RNA, Messenger; S

2023
Sulforaphane inhibits CD44v6/YAP1/TEAD signaling to suppress the cancer phenotype.
    Molecular carcinogenesis, 2023, Volume: 62, Issue:2

    Topics: Adaptor Proteins, Signal Transducing; Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Proliferation

2023
Combination cisplatin and sulforaphane treatment reduces proliferation, invasion, and tumor formation in epidermal squamous cell carcinoma.
    Molecular carcinogenesis, 2018, Volume: 57, Issue:1

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Carcinoma, Squamous Cell; Cell L

2018
Sulforaphane suppresses PRMT5/MEP50 function in epidermal squamous cell carcinoma leading to reduced tumor formation.
    Carcinogenesis, 2017, 08-01, Volume: 38, Issue:8

    Topics: Adaptor Proteins, Signal Transducing; Animals; Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Move

2017
Broccoli extract improves chemotherapeutic drug efficacy against head-neck squamous cell carcinomas.
    Medical oncology (Northwood, London, England), 2018, Aug-04, Volume: 35, Issue:9

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Carcinoma, Squamous Cell; Cell Line

2018
Sulforaphane metabolites inhibit migration and invasion via microtubule-mediated Claudins dysfunction or inhibition of autolysosome formation in human non-small cell lung cancer cells.
    Cell death & disease, 2019, 03-15, Volume: 10, Issue:4

    Topics: A549 Cells; Antineoplastic Agents; Autophagosomes; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamo

2019
Sulforaphane targets cancer stemness and tumor initiating properties in oral squamous cell carcinomas via miR-200c induction.
    Journal of the Formosan Medical Association = Taiwan yi zhi, 2017, Volume: 116, Issue:1

    Topics: Aldehyde Dehydrogenase 1 Family; Animals; Anticarcinogenic Agents; Carcinoma, Squamous Cell; Cell Li

2017
Effect of (R)L-sulforaphane on 5-aminolevulinic acid-mediated photodynamic therapy.
    Translational research : the journal of laboratory and clinical medicine, 2008, Volume: 152, Issue:3

    Topics: Aminolevulinic Acid; Anticarcinogenic Agents; Carcinoma, Squamous Cell; Cell Line, Tumor; Drug Scree

2008
Sulforaphane enhances caspase-dependent apoptosis through inhibition of cyclooxygenase-2 expression in human oral squamous carcinoma cells and nude mouse xenograft model.
    Oral oncology, 2009, Volume: 45, Issue:8

    Topics: Animals; Anticarcinogenic Agents; Apoptosis; Carcinoma, Squamous Cell; Caspases; Cyclooxygenase 2 In

2009
Inhibition of activator protein-1 by sulforaphane involves interaction with cysteine in the cFos DNA-binding domain: implications for chemoprevention of UVB-induced skin cancer.
    Cancer research, 2009, Sep-01, Volume: 69, Issue:17

    Topics: Animals; Anticarcinogenic Agents; Binding Sites; Carcinoma, Squamous Cell; Cysteine; Disease Models,

2009
Radiosensitization of head and neck cancer cells by the phytochemical agent sulforaphane.
    Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 2011, Volume: 187, Issue:9

    Topics: Anticarcinogenic Agents; Apoptosis; Blotting, Western; Carcinoma, Squamous Cell; Cell Division; Cell

2011
Reversal of hypermethylation and reactivation of p16INK4a, RARbeta, and MGMT genes by genistein and other isoflavones from soy.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2005, Oct-01, Volume: 11, Issue:19 Pt 1

    Topics: Anticarcinogenic Agents; Antineoplastic Agents; Azacitidine; Carcinoma, Squamous Cell; Cell Line, Tu

2005