sulforaphane has been researched along with Carcinoma, Epidermoid in 13 studies
sulforaphane: from Cardaria draba L.
sulforaphane : An isothiocyanate having a 4-(methylsulfinyl)butyl group attached to the nitrogen.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Sulforaphane appears to inhibit sCC progression by impacting its growth and invasion ability, and regulates miR-199a-5p/Sirt1 and CD44ICD signaling pathways, and may be utilized to develop a curative approach for sSCC." | 1.91 | Sulforaphane suppresses skin squamous cell carcinoma cells proliferation through miR-199a-5p/Sirt1/CD44ICD signaling pathway. ( Ai, P; Chen, SZ; Lei, SY; Zhang, Y, 2023) |
| "Sulforaphane (SFN) is a promising cancer prevention and treatment agent that strongly suppresses the cutaneous squamous cell carcinoma (CSCC) cell cancer phenotype." | 1.91 | Sulforaphane inhibits CD44v6/YAP1/TEAD signaling to suppress the cancer phenotype. ( Adhikary, G; Chen, X; Eckert, RL; Ma, E; Naselsky, W; Newland, JJ; Xu, W, 2023) |
| "Sulforaphane (SFN) is an important diet-derived cancer prevention agent that is known to possess a reactive isothiocyanate group and has potent anticancer activity." | 1.72 | Sulforaphane covalently interacts with the transglutaminase 2 cancer maintenance protein to alter its structure and suppress its activity. ( Adhikary, G; Eckert, RL; Gates, EWJ; Godoy-Ruiz, R; Keillor, JW; Lakowicz, JR; Puranik, P; Rorke, EA; Szmacinski, H; Weber, DJ, 2022) |
| "Sulforaphane is a diet-derived cancer prevention agent that is effective in suppressing tumor growth in animal models of skin cancer." | 1.48 | Combination cisplatin and sulforaphane treatment reduces proliferation, invasion, and tumor formation in epidermal squamous cell carcinoma. ( Adhikary, G; Eckert, RL; George, N; Grun, D; Kerr, C, 2018) |
| "Sulforaphane treatment resulted in a dose-dependent increase in the levels of tumor suppressive miR200c." | 1.46 | Sulforaphane targets cancer stemness and tumor initiating properties in oral squamous cell carcinomas via miR-200c induction. ( Liao, YW; Liu, CM; Lu, MY; Peng, CY; Tsai, ML; Yeh, JC; Yu, CC; Yu, CH, 2017) |
| "Sulforaphane is a naturally occurring compound found in broccoli and other cruciferous vegetables." | 1.37 | Radiosensitization of head and neck cancer cells by the phytochemical agent sulforaphane. ( Brunner, M; Czembirek, C; Eder-Czembirek, C; Fahim, T; Heiduschka, G; Kotowski, U; Schmidt, R; Thurnher, D, 2011) |
| "(R)L-sulforaphane (SF) is a compound that protects against erythema, but it can also induce DNA fragmentation that leads to cell death by apoptosis." | 1.35 | Effect of (R)L-sulforaphane on 5-aminolevulinic acid-mediated photodynamic therapy. ( Juzeniene, A; Mikolajewska, P; Moan, J, 2008) |
| "In this study, we found that oral squamous cell carcinomas (OSCCs) in Korean patients have a high level of COX-2 expression when compared with normal mucosa." | 1.35 | Sulforaphane enhances caspase-dependent apoptosis through inhibition of cyclooxygenase-2 expression in human oral squamous carcinoma cells and nude mouse xenograft model. ( Cho, NP; Cho, SD; Choi, IS; Choi, KH; Choi, SH; Han, HS; Jung, JY; Kim, HJ; Kong, G; Leem, DH; Moon, KS; Soh, Y, 2009) |
| "Sulforaphane is an isothiocyanate derived from cruciferous vegetables that has been linked to decreased risk of certain cancers." | 1.35 | Inhibition of activator protein-1 by sulforaphane involves interaction with cysteine in the cFos DNA-binding domain: implications for chemoprevention of UVB-induced skin cancer. ( Bowden, GT; Dickinson, SE; Melton, TF; Olson, ER; Saboda, K; Zhang, J, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (30.77) | 29.6817 |
| 2010's | 6 (46.15) | 24.3611 |
| 2020's | 3 (23.08) | 2.80 |
| Authors | Studies |
|---|---|
| Rorke, EA | 1 |
| Adhikary, G | 4 |
| Szmacinski, H | 1 |
| Lakowicz, JR | 1 |
| Weber, DJ | 1 |
| Godoy-Ruiz, R | 1 |
| Puranik, P | 1 |
| Keillor, JW | 1 |
| Gates, EWJ | 1 |
| Eckert, RL | 4 |
| Zhang, Y | 1 |
| Ai, P | 1 |
| Chen, SZ | 1 |
| Lei, SY | 1 |
| Chen, X | 1 |
| Ma, E | 1 |
| Newland, JJ | 1 |
| Naselsky, W | 1 |
| Xu, W | 1 |
| Kerr, C | 1 |
| Grun, D | 2 |
| George, N | 1 |
| Saha, K | 1 |
| Fisher, ML | 1 |
| Elkashty, OA | 1 |
| Ashry, R | 1 |
| Elghanam, GA | 1 |
| Pham, HM | 1 |
| Su, X | 1 |
| Stegen, C | 1 |
| Tran, SD | 1 |
| Zheng, Z | 1 |
| Lin, K | 1 |
| Hu, Y | 1 |
| Zhou, Y | 1 |
| Ding, X | 1 |
| Wang, Y | 1 |
| Wu, W | 1 |
| Liu, CM | 1 |
| Peng, CY | 1 |
| Liao, YW | 1 |
| Lu, MY | 1 |
| Tsai, ML | 1 |
| Yeh, JC | 1 |
| Yu, CH | 1 |
| Yu, CC | 1 |
| Mikolajewska, P | 1 |
| Juzeniene, A | 1 |
| Moan, J | 1 |
| Cho, NP | 1 |
| Han, HS | 1 |
| Leem, DH | 1 |
| Choi, IS | 1 |
| Jung, JY | 1 |
| Kim, HJ | 1 |
| Moon, KS | 1 |
| Choi, KH | 1 |
| Soh, Y | 1 |
| Kong, G | 1 |
| Cho, SD | 1 |
| Choi, SH | 1 |
| Dickinson, SE | 1 |
| Melton, TF | 1 |
| Olson, ER | 1 |
| Zhang, J | 1 |
| Saboda, K | 1 |
| Bowden, GT | 1 |
| Kotowski, U | 1 |
| Heiduschka, G | 1 |
| Brunner, M | 1 |
| Czembirek, C | 1 |
| Eder-Czembirek, C | 1 |
| Schmidt, R | 1 |
| Fahim, T | 1 |
| Thurnher, D | 1 |
| Fang, MZ | 1 |
| Chen, D | 1 |
| Sun, Y | 1 |
| Jin, Z | 1 |
| Christman, JK | 1 |
| Yang, CS | 1 |
13 other studies available for sulforaphane and Carcinoma, Epidermoid
| Article | Year |
|---|---|
Sulforaphane covalently interacts with the transglutaminase 2 cancer maintenance protein to alter its structure and suppress its activity.
Topics: Animals; Antineoplastic Agents; Binding Sites; Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Prol | 2022 |
Sulforaphane suppresses skin squamous cell carcinoma cells proliferation through miR-199a-5p/Sirt1/CD44ICD signaling pathway.
Topics: Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Proliferation; Humans; MicroRNAs; RNA, Messenger; S | 2023 |
Sulforaphane inhibits CD44v6/YAP1/TEAD signaling to suppress the cancer phenotype.
Topics: Adaptor Proteins, Signal Transducing; Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Proliferation | 2023 |
Combination cisplatin and sulforaphane treatment reduces proliferation, invasion, and tumor formation in epidermal squamous cell carcinoma.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Carcinoma, Squamous Cell; Cell L | 2018 |
Sulforaphane suppresses PRMT5/MEP50 function in epidermal squamous cell carcinoma leading to reduced tumor formation.
Topics: Adaptor Proteins, Signal Transducing; Animals; Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Move | 2017 |
Broccoli extract improves chemotherapeutic drug efficacy against head-neck squamous cell carcinomas.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Carcinoma, Squamous Cell; Cell Line | 2018 |
Sulforaphane metabolites inhibit migration and invasion via microtubule-mediated Claudins dysfunction or inhibition of autolysosome formation in human non-small cell lung cancer cells.
Topics: A549 Cells; Antineoplastic Agents; Autophagosomes; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamo | 2019 |
Sulforaphane targets cancer stemness and tumor initiating properties in oral squamous cell carcinomas via miR-200c induction.
Topics: Aldehyde Dehydrogenase 1 Family; Animals; Anticarcinogenic Agents; Carcinoma, Squamous Cell; Cell Li | 2017 |
Effect of (R)L-sulforaphane on 5-aminolevulinic acid-mediated photodynamic therapy.
Topics: Aminolevulinic Acid; Anticarcinogenic Agents; Carcinoma, Squamous Cell; Cell Line, Tumor; Drug Scree | 2008 |
Sulforaphane enhances caspase-dependent apoptosis through inhibition of cyclooxygenase-2 expression in human oral squamous carcinoma cells and nude mouse xenograft model.
Topics: Animals; Anticarcinogenic Agents; Apoptosis; Carcinoma, Squamous Cell; Caspases; Cyclooxygenase 2 In | 2009 |
Inhibition of activator protein-1 by sulforaphane involves interaction with cysteine in the cFos DNA-binding domain: implications for chemoprevention of UVB-induced skin cancer.
Topics: Animals; Anticarcinogenic Agents; Binding Sites; Carcinoma, Squamous Cell; Cysteine; Disease Models, | 2009 |
Radiosensitization of head and neck cancer cells by the phytochemical agent sulforaphane.
Topics: Anticarcinogenic Agents; Apoptosis; Blotting, Western; Carcinoma, Squamous Cell; Cell Division; Cell | 2011 |
Reversal of hypermethylation and reactivation of p16INK4a, RARbeta, and MGMT genes by genistein and other isoflavones from soy.
Topics: Anticarcinogenic Agents; Antineoplastic Agents; Azacitidine; Carcinoma, Squamous Cell; Cell Line, Tu | 2005 |