Page last updated: 2024-11-04

sulforaphane and Carcinoid Tumor

sulforaphane has been researched along with Carcinoid Tumor in 2 studies

sulforaphane: from Cardaria draba L.
sulforaphane : An isothiocyanate having a 4-(methylsulfinyl)butyl group attached to the nitrogen.

Carcinoid Tumor: A usually small, slow-growing neoplasm composed of islands of rounded, oxyphilic, or spindle-shaped cells of medium size, with moderately small vesicular nuclei, and covered by intact mucosa with a yellow cut surface. The tumor can occur anywhere in the gastrointestinal tract (and in the lungs and other sites); approximately 90% arise in the appendix. It is now established that these tumors are of neuroendocrine origin and derive from a primitive stem cell. (From Stedman, 25th ed & Holland et al., Cancer Medicine, 3d ed, p1182)

Research Excerpts

ExcerptRelevanceReference
"Bronchial carcinoids are neuroendocrine tumors that present as typical (TC) and atypical (AC) variants, the latter being more aggressive, invasive and metastatic."5.51Human bronchial carcinoid tumor initiating cells are targeted by the combination of acetazolamide and sulforaphane. ( Baluch, N; Bayat Mokhtari, R; Cheng, HL; Das, B; Kumar, S; Morgatskaya, E; Muscarella, LA; Sparaneo, A; Yeger, H; Zhao, S, 2019)
"Bronchial carcinoids are neuroendocrine tumors that present as typical (TC) and atypical (AC) variants, the latter being more aggressive, invasive and metastatic."1.51Human bronchial carcinoid tumor initiating cells are targeted by the combination of acetazolamide and sulforaphane. ( Baluch, N; Bayat Mokhtari, R; Cheng, HL; Das, B; Kumar, S; Morgatskaya, E; Muscarella, LA; Sparaneo, A; Yeger, H; Zhao, S, 2019)
"In vitro studies were used for the dose-response (AlamarBlue) effects of acetazolamide (AZ) and sulforaphane (SFN) on clonogenicity, serotonin-induced growth effect and serotonin content (LC-MS) on H-727 (TC) and H-720 (AC) bronchial carcinoid cell lines and their derived NOD/SCID mice subcutaneous xenografts."1.39Combination of carbonic anhydrase inhibitor, acetazolamide, and sulforaphane, reduces the viability and growth of bronchial carcinoid cell lines. ( Adeli, K; Cutz, E; Islam, SS; Kumar, S; Mokhtari, RB; Yazdanpanah, M; Yeger, H, 2013)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bayat Mokhtari, R1
Baluch, N1
Morgatskaya, E1
Kumar, S2
Sparaneo, A1
Muscarella, LA1
Zhao, S1
Cheng, HL1
Das, B1
Yeger, H2
Mokhtari, RB1
Islam, SS1
Yazdanpanah, M1
Adeli, K1
Cutz, E1

Other Studies

2 other studies available for sulforaphane and Carcinoid Tumor

ArticleYear
Human bronchial carcinoid tumor initiating cells are targeted by the combination of acetazolamide and sulforaphane.
    BMC cancer, 2019, Aug-30, Volume: 19, Issue:1

    Topics: Acetazolamide; Animals; Anticarcinogenic Agents; Antineoplastic Combined Chemotherapy Protocols; Bro

2019
Combination of carbonic anhydrase inhibitor, acetazolamide, and sulforaphane, reduces the viability and growth of bronchial carcinoid cell lines.
    BMC cancer, 2013, Aug-08, Volume: 13

    Topics: Acetazolamide; Animals; Antineoplastic Agents; Bronchial Neoplasms; Carbonic Anhydrase Inhibitors; C

2013