sulforaphane has been researched along with Carcinogenesis in 9 studies
sulforaphane: from Cardaria draba L.
sulforaphane : An isothiocyanate having a 4-(methylsulfinyl)butyl group attached to the nitrogen.
Carcinogenesis: The origin, production or development of cancer through genotypic and phenotypic changes which upset the normal balance between cell proliferation and cell death. Carcinogenesis generally requires a constellation of steps, which may occur quickly or over a period of many years.
| Excerpt | Relevance | Reference |
|---|---|---|
| " In this study we aimed to examine whether a chemical activator of NRF2, sulforaphane (SFN), may have chemopreventive effects on oxidative stress-associated oral carcinogenesis." | 7.83 | Chemoprevention of oxidative stress-associated oral carcinogenesis by sulforaphane depends on NRF2 and the isothiocyanate moiety. ( Chen, H; Chen, X; Chen, XL; Kapita, M; Lan, A; Li, W; Liu, Y; Palko, O; Prigge, JR; Schmidt, EE; Sun, Z; Xiong, Z; Zhang, X; Zhou, S, 2016) |
| "These results suggest that once hepatocarcinogenesis is initiated, SFN may stimulate tumor progression." | 5.72 | Tumor Promoting Effects of Sulforaphane on Diethylnitrosamine-Induced Murine Hepatocarcinogenesis. ( Fang, X; Kim, DH; Kim, SH; Kim, SJ; Saeidi, S; Surh, YJ; Zheng, J, 2022) |
| " In this study we aimed to examine whether a chemical activator of NRF2, sulforaphane (SFN), may have chemopreventive effects on oxidative stress-associated oral carcinogenesis." | 3.83 | Chemoprevention of oxidative stress-associated oral carcinogenesis by sulforaphane depends on NRF2 and the isothiocyanate moiety. ( Chen, H; Chen, X; Chen, XL; Kapita, M; Lan, A; Li, W; Liu, Y; Palko, O; Prigge, JR; Schmidt, EE; Sun, Z; Xiong, Z; Zhang, X; Zhou, S, 2016) |
| "Combined treatment with epigallocatechin-3-gallate in GTPs and sulforaphane in BSp resulted in a synergistic inhibition of breast cancer cellular growth." | 3.83 | Combinatorial epigenetic mechanisms and efficacy of early breast cancer inhibition by nutritive botanicals. ( Buckhaults, P; Cui, X; Li, Y; Tollefsbol, TO, 2016) |
| "Sulforaphane (SFN) has been shown to induce the production of reactive oxygen species (ROS) and inhibit epidermal growth factor receptor (EGFR)-mediated signaling in non-small-cell lung cancer (NSCLC)." | 1.51 | High levels of EGFR prevent sulforaphane-induced reactive oxygen species-mediated apoptosis in non-small-cell lung cancer cells. ( Chen, CC; Chen, CY; Huang, KY; Shih, YM; Wang, TH, 2019) |
| "Sulforaphane (SFN) is a phytochemical derived from cruciferous vegetables that induces anti-proliferative and pro-apoptotic responses in prostate cancer cells, but not in normal prostate cells." | 1.40 | Transcriptome analysis reveals a dynamic and differential transcriptional response to sulforaphane in normal and prostate cancer cells and suggests a role for Sp1 in chemoprevention. ( Beaver, LM; Buchanan, A; Chang, JH; Dashwood, RH; Ho, E; Löhr, CV; Riscoe, AN; Sokolowski, EI; Williams, DE; Wong, CP, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 8 (88.89) | 24.3611 |
| 2020's | 1 (11.11) | 2.80 |
| Authors | Studies |
|---|---|
| Zheng, J | 1 |
| Kim, DH | 1 |
| Fang, X | 1 |
| Kim, SH | 1 |
| Saeidi, S | 1 |
| Kim, SJ | 1 |
| Surh, YJ | 1 |
| Wang, TH | 1 |
| Chen, CC | 1 |
| Huang, KY | 1 |
| Shih, YM | 1 |
| Chen, CY | 1 |
| Wang, Y | 1 |
| Mandal, AK | 1 |
| Son, YO | 1 |
| Pratheeshkumar, P | 1 |
| Wise, JTF | 1 |
| Wang, L | 1 |
| Zhang, Z | 1 |
| Shi, X | 1 |
| Chen, Z | 1 |
| Hsu, YC | 1 |
| Chang, SJ | 1 |
| Wang, MY | 1 |
| Chen, YL | 1 |
| Huang, TY | 1 |
| Beaver, LM | 1 |
| Buchanan, A | 1 |
| Sokolowski, EI | 1 |
| Riscoe, AN | 1 |
| Wong, CP | 1 |
| Chang, JH | 1 |
| Löhr, CV | 1 |
| Williams, DE | 1 |
| Dashwood, RH | 1 |
| Ho, E | 1 |
| Jiang, LL | 1 |
| Zhou, SJ | 1 |
| Zhang, XM | 1 |
| Chen, HQ | 1 |
| Liu, W | 1 |
| Fan, P | 1 |
| Zhang, Y | 1 |
| Liu, L | 1 |
| Zhao, Z | 1 |
| Yin, Y | 1 |
| Xiao, X | 1 |
| Bauer, N | 1 |
| Gladkich, J | 1 |
| Mattern, J | 1 |
| Gao, C | 1 |
| Schemmer, P | 1 |
| Gross, W | 1 |
| Herr, I | 1 |
| Lan, A | 1 |
| Li, W | 1 |
| Liu, Y | 1 |
| Xiong, Z | 1 |
| Zhang, X | 1 |
| Zhou, S | 1 |
| Palko, O | 1 |
| Chen, H | 1 |
| Kapita, M | 1 |
| Prigge, JR | 1 |
| Schmidt, EE | 1 |
| Chen, X | 1 |
| Sun, Z | 1 |
| Chen, XL | 1 |
| Li, Y | 1 |
| Buckhaults, P | 1 |
| Cui, X | 1 |
| Tollefsbol, TO | 1 |
9 other studies available for sulforaphane and Carcinogenesis
| Article | Year |
|---|---|
Tumor Promoting Effects of Sulforaphane on Diethylnitrosamine-Induced Murine Hepatocarcinogenesis.
Topics: Animals; Carcinogenesis; Diethylnitrosamine; Isothiocyanates; Male; Mice; Mice, Inbred C57BL; NF-E2- | 2022 |
High levels of EGFR prevent sulforaphane-induced reactive oxygen species-mediated apoptosis in non-small-cell lung cancer cells.
Topics: Animals; Anticarcinogenic Agents; Antioxidants; Apoptosis; Carcinogenesis; Carcinoma, Non-Small-Cell | 2019 |
Roles of ROS, Nrf2, and autophagy in cadmium-carcinogenesis and its prevention by sulforaphane.
Topics: Anticarcinogenic Agents; Apoptosis Regulatory Proteins; Autophagy; Cadmium; Carcinogenesis; Cell Lin | 2018 |
Growth inhibition and apoptosis of neuroblastoma cells through ROS-independent MEK/ERK activation by sulforaphane.
Topics: Anticarcinogenic Agents; Apoptosis; Carcinogenesis; Caspase 3; Caspase 9; Cell Line, Tumor; Cell Mov | 2013 |
Transcriptome analysis reveals a dynamic and differential transcriptional response to sulforaphane in normal and prostate cancer cells and suggests a role for Sp1 in chemoprevention.
Topics: Anticarcinogenic Agents; Carcinogenesis; Cell Line, Tumor; Cells, Cultured; Chemoprevention; Dietary | 2014 |
Sulforaphane suppresses in vitro and in vivo lung tumorigenesis through downregulation of HDAC activity.
Topics: Acetylation; Animals; Apoptosis; Carcinogenesis; Cell Cycle; Cell Cycle Checkpoints; Cell Line, Tumo | 2016 |
Continuous exposure of pancreatic cancer cells to dietary bioactive agents does not induce drug resistance unlike chemotherapy.
Topics: Antineoplastic Agents; Biomarkers, Tumor; Carcinogenesis; Cell Line, Tumor; Cell Survival; Clone Cel | 2016 |
Chemoprevention of oxidative stress-associated oral carcinogenesis by sulforaphane depends on NRF2 and the isothiocyanate moiety.
Topics: 4-Nitroquinoline-1-oxide; Animals; Anticarcinogenic Agents; Carcinogenesis; Carcinogens; Chemopreven | 2016 |
Combinatorial epigenetic mechanisms and efficacy of early breast cancer inhibition by nutritive botanicals.
Topics: Animals; Antineoplastic Agents, Phytogenic; Brassica; Breast Neoplasms; Carcinogenesis; Catechin; Ce | 2016 |