sulforaphane has been researched along with Cancer of Colon in 43 studies
sulforaphane: from Cardaria draba L.
sulforaphane : An isothiocyanate having a 4-(methylsulfinyl)butyl group attached to the nitrogen.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Chronic inflammation and selenium deficiency are considered as risk factors for colon cancer." | 7.78 | Glutathione peroxidase-2 and selenium decreased inflammation and tumors in a mouse model of inflammation-associated carcinogenesis whereas sulforaphane effects differed with selenium supply. ( Banning, A; Brauer, MN; Brigelius-Flohé, R; Chu, FF; Esworthy, RS; Florian, S; Iori, R; Kipp, AP; Krehl, S; Loewinger, M; Wessjohann, LA, 2012) |
| "Sulforaphane is a cruciferous vegetable-derived isothiocyanate with promising chemopreventive and therapeutic activities." | 5.42 | Sulforaphane down-regulates SKP2 to stabilize p27(KIP1) for inducing antiproliferation in human colon adenocarcinoma cells. ( Chang, CC; Chi-Hung Or, R; Chung, YK; Lu, CH; Ouyang, WT; Yang, SY, 2015) |
| "Chronic inflammation and selenium deficiency are considered as risk factors for colon cancer." | 3.78 | Glutathione peroxidase-2 and selenium decreased inflammation and tumors in a mouse model of inflammation-associated carcinogenesis whereas sulforaphane effects differed with selenium supply. ( Banning, A; Brauer, MN; Brigelius-Flohé, R; Chu, FF; Esworthy, RS; Florian, S; Iori, R; Kipp, AP; Krehl, S; Loewinger, M; Wessjohann, LA, 2012) |
| "The association of decreased cancer risk with intake of cruciferous vegetables and selenium is stronger than that reported for fruits and vegetables in general." | 2.43 | Part of the series: from dietary antioxidants to regulators in cellular signaling and gene regulation. Sulforaphane and selenium, partners in adaptive response and prevention of cancer. ( Banning, A; Brigelius-Flohé, R, 2006) |
| " The aim of this in silico investigation was to predict SFN-induced adverse effects in CRC patients by computational analysis." | 1.72 | Predicting sulforaphane-induced adverse effects in colon cancer patients via in silico investigation. ( Antonijević, B; Baralić, K; Bozic, D; Bulat, Z; Ćurčić, M; Djordjević, AB; Miljaković, EA; Yang, L; Zhang, Y; Živančević, K; Đukić-Ćosić, D, 2022) |
| "The data suggest that colon cancer cells respond to dietary components differently under different conditions." | 1.62 | Association between histone deacetylase activity and vitamin D-dependent gene expressions in relation to sulforaphane in human colorectal cancer cells. ( Hossain, S; Liu, Z; Wood, RJ, 2021) |
| "Sulforaphane is a cruciferous vegetable-derived isothiocyanate with promising chemopreventive and therapeutic activities." | 1.42 | Sulforaphane down-regulates SKP2 to stabilize p27(KIP1) for inducing antiproliferation in human colon adenocarcinoma cells. ( Chang, CC; Chi-Hung Or, R; Chung, YK; Lu, CH; Ouyang, WT; Yang, SY, 2015) |
| "Treatment with sulforaphane inhibited hypoxia-induced vascular endothelial growth factor (VEGF) expression in HCT116 cells." | 1.42 | Sulforaphane inhibits hypoxia-induced HIF-1α and VEGF expression and migration of human colon cancer cells. ( Hwang, SY; Im, E; Kang, YJ; Kim, DH; Kim, MJ; Kim, ND; Sung, B; Yoon, JH, 2015) |
| "Here, we show in human colon cancer cells that dietary isothiocyanates (ITCs) inhibit HDAC activity and increase HDAC protein turnover with the potency proportional to alkyl chain length, i." | 1.39 | HDAC turnover, CtIP acetylation and dysregulated DNA damage signaling in colon cancer cells treated with sulforaphane and related dietary isothiocyanates. ( Bisson, WH; Dashwood, RH; Dashwood, WM; Ho, E; Kidane, AI; Löhr, CV; Rajendran, P; Williams, DE; Yu, TW, 2013) |
| "Sulforaphane (SFN) is a naturally occurring chemopreventive agent; the induction of cell cycle arrest and apoptosis is a key mechanism by which SFN exerts its colon cancer prevention." | 1.37 | Prolonged sulforaphane treatment activates survival signaling in nontumorigenic NCM460 colon cells but apoptotic signaling in tumorigenic HCT116 colon cells. ( Botnen, JH; Moyer, MP; Trujillo, ON; Zeng, H, 2011) |
| "The latter pathway predominates in colon cancer cells exposed continuously to SFN, whereas the former pathway is likely to be favored when SFN has been removed within 24 h, allowing recovery from cell cycle arrest." | 1.37 | Histone deacetylase turnover and recovery in sulforaphane-treated colon cancer cells: competing actions of 14-3-3 and Pin1 in HDAC3/SMRT corepressor complex dissociation/reassembly. ( Dashwood, RH; Dashwood, WM; Delage, B; Ho, E; Rajendran, P; Williams, DE; Wuth, B; Yu, TW, 2011) |
| "Human colon cancer cells of the line Caco-2 were cultured and added with SFN of different terminal concentrations, all below the concentration of IC(50)." | 1.33 | [Induction of uridine 5'-diphosphate-glucuronosyltransferase gene expression by sulforaphane and its mechanism: experimental study in human colon cancel cells]. ( Chen, J; Li, YQ; Wang, M; Xu, XQ; Yuan, MB; Zhong, N, 2005) |
| "Treatment with sulforaphane (15 microM), PEITC (10 microM), indole-3-carbinol (10 microM) and 3,3'-diindolylmethane (10 microM) induced PARP cleavage after 24 and 48 h in both 40-16 and the 379." | 1.33 | Comparison of growth inhibition profiles and mechanisms of apoptosis induction in human colon cancer cell lines by isothiocyanates and indoles from Brassicaceae. ( Barillari, J; Bartsch, H; Gerhäuser, C; Iori, R; Lichtenberg, M; Pappa, G, 2006) |
| "HT-29 colon cancer cells were cultured in 96-well microtitre plates." | 1.32 | Sulforaphane inhibits growth of a colon cancer cell line. ( Frydoonfar, HR; McGrath, DR; Spigelman, AD, 2004) |
| "Sulforaphane is an isothiocyanate that is present naturally in widely consumed vegetables and has a particularly high concentration in broccoli." | 1.31 | Sulforaphane, a naturally occurring isothiocyanate, induces cell cycle arrest and apoptosis in HT29 human colon cancer cells. ( Cassar, G; Chevolleau, S; Dupont, MA; Gamet-Payrastre, L; Gasc, N; Li, P; Lumeau, S; Tercé, F; Tulliez, J, 2000) |
| " SFN and PEITC and their NAC conjugates were administered by gavage either three times weekly for 8 weeks (5 and 20 micromol, respectively) after AOM dosing (post-initiation stage) or once daily for 3 days (20 and 50 micromol, respectively) before AOM treatment (initiation stage)." | 1.31 | Chemoprevention of colonic aberrant crypt foci in Fischer rats by sulforaphane and phenethyl isothiocyanate. ( Chung, FL; Conaway, CC; Rao, CV; Reddy, BS, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (2.33) | 18.2507 |
| 2000's | 14 (32.56) | 29.6817 |
| 2010's | 22 (51.16) | 24.3611 |
| 2020's | 6 (13.95) | 2.80 |
| Authors | Studies |
|---|---|
| Melchini, A | 1 |
| Needs, PW | 1 |
| Mithen, RF | 2 |
| Traka, MH | 1 |
| Li, S | 1 |
| Xu, Z | 1 |
| Alrobaian, M | 1 |
| Afzal, O | 1 |
| Kazmi, I | 1 |
| Almalki, WH | 1 |
| Altamimi, ASA | 1 |
| Al-Abbasi, FA | 1 |
| Alharbi, KS | 1 |
| Altowayan, WM | 1 |
| Singh, T | 1 |
| Akhter, MH | 1 |
| Gupta, M | 1 |
| Rahman, M | 1 |
| Beg, S | 1 |
| Bozic, D | 1 |
| Baralić, K | 1 |
| Živančević, K | 1 |
| Miljaković, EA | 1 |
| Ćurčić, M | 1 |
| Antonijević, B | 1 |
| Djordjević, AB | 1 |
| Bulat, Z | 1 |
| Zhang, Y | 1 |
| Yang, L | 1 |
| Đukić-Ćosić, D | 1 |
| Čižauskaitė, A | 1 |
| Šimčikas, D | 1 |
| Schultze, D | 1 |
| Kallifatidis, G | 1 |
| Bruns, H | 1 |
| Čekauskas, A | 1 |
| Herr, I | 1 |
| Baušys, A | 1 |
| Strupas, K | 1 |
| Schemmer, P | 1 |
| Santana-Gálvez, J | 1 |
| Villela-Castrejón, J | 1 |
| Serna-Saldívar, SO | 1 |
| Cisneros-Zevallos, L | 1 |
| Jacobo-Velázquez, DA | 1 |
| Hossain, S | 1 |
| Liu, Z | 1 |
| Wood, RJ | 1 |
| Milczarek, M | 1 |
| Pogorzelska, A | 1 |
| Wiktorska, K | 1 |
| Bessler, H | 1 |
| Djaldetti, M | 1 |
| Okonkwo, A | 1 |
| Mitra, J | 1 |
| Johnson, GS | 2 |
| Li, L | 1 |
| Dashwood, WM | 4 |
| Hegde, ML | 1 |
| Yue, C | 1 |
| Dashwood, RH | 4 |
| Rajendran, P | 4 |
| Tafakh, MS | 1 |
| Saidijam, M | 1 |
| Ranjbarnejad, T | 1 |
| Malih, S | 1 |
| Mirzamohammadi, S | 1 |
| Najafi, R | 1 |
| Langner, E | 1 |
| Lemieszek, MK | 1 |
| Rzeski, W | 1 |
| Kidane, AI | 1 |
| Yu, TW | 2 |
| Bisson, WH | 1 |
| Löhr, CV | 1 |
| Ho, E | 3 |
| Williams, DE | 3 |
| Lippmann, D | 1 |
| Lehmann, C | 1 |
| Florian, S | 2 |
| Barknowitz, G | 1 |
| Haack, M | 1 |
| Mewis, I | 1 |
| Wiesner, M | 1 |
| Schreiner, M | 1 |
| Glatt, H | 1 |
| Brigelius-Flohé, R | 3 |
| Kipp, AP | 2 |
| Chung, YK | 1 |
| Chi-Hung Or, R | 1 |
| Lu, CH | 1 |
| Ouyang, WT | 1 |
| Yang, SY | 1 |
| Chang, CC | 1 |
| Wang, Y | 1 |
| Dacosta, C | 1 |
| Wang, W | 2 |
| Zhou, Z | 1 |
| Liu, M | 1 |
| Bao, Y | 4 |
| Kim, DH | 1 |
| Sung, B | 1 |
| Kang, YJ | 1 |
| Hwang, SY | 1 |
| Kim, MJ | 2 |
| Yoon, JH | 1 |
| Im, E | 1 |
| Kim, ND | 1 |
| Erzinger, MM | 1 |
| Bovet, C | 1 |
| Hecht, KM | 1 |
| Senger, S | 1 |
| Winiker, P | 1 |
| Sobotzki, N | 1 |
| Cristea, S | 1 |
| Beerenwinkel, N | 1 |
| Shay, JW | 1 |
| Marra, G | 1 |
| Wollscheid, B | 1 |
| Sturla, SJ | 1 |
| Liu, KC | 1 |
| Shih, TY | 1 |
| Kuo, CL | 1 |
| Ma, YS | 1 |
| Yang, JL | 1 |
| Wu, PP | 1 |
| Huang, YP | 1 |
| Lai, KC | 1 |
| Chung, JG | 1 |
| Li, J | 1 |
| Beaver, LM | 1 |
| Sun, D | 2 |
| Martin, SL | 1 |
| Kala, R | 1 |
| Tollefsbol, TO | 1 |
| Mastrangelo, L | 1 |
| Cassidy, A | 1 |
| Mulholland, F | 1 |
| Rudolf, E | 3 |
| Andelová, H | 2 |
| Cervinka, M | 3 |
| Nishikawa, T | 1 |
| Tsuno, NH | 1 |
| Okaji, Y | 1 |
| Shuno, Y | 1 |
| Sasaki, K | 1 |
| Hongo, K | 1 |
| Sunami, E | 1 |
| Kitayama, J | 1 |
| Takahashi, K | 1 |
| Nagawa, H | 1 |
| Kim, SH | 1 |
| Lim, SJ | 1 |
| Zeng, H | 1 |
| Trujillo, ON | 1 |
| Moyer, MP | 1 |
| Botnen, JH | 1 |
| Delage, B | 1 |
| Wuth, B | 1 |
| Hashem, FA | 1 |
| Motawea, H | 1 |
| El-Shabrawy, AE | 1 |
| Shaker, K | 1 |
| El-Sherbini, S | 1 |
| Krehl, S | 1 |
| Loewinger, M | 1 |
| Banning, A | 2 |
| Wessjohann, LA | 1 |
| Brauer, MN | 1 |
| Iori, R | 2 |
| Esworthy, RS | 1 |
| Chu, FF | 1 |
| Wang, M | 2 |
| Chen, S | 1 |
| Wang, S | 2 |
| Chen, J | 2 |
| Li, Y | 1 |
| Han, W | 1 |
| Yang, X | 1 |
| Gao, HQ | 1 |
| Frydoonfar, HR | 1 |
| McGrath, DR | 1 |
| Spigelman, AD | 1 |
| Svehlíková, V | 1 |
| Jakubíková, J | 1 |
| Williamson, G | 1 |
| Mithen, R | 1 |
| Li, YQ | 1 |
| Zhong, N | 1 |
| Xu, XQ | 1 |
| Yuan, MB | 1 |
| Traka, M | 1 |
| Gasper, AV | 1 |
| Smith, JA | 1 |
| Hawkey, CJ | 1 |
| Pappa, G | 3 |
| Lichtenberg, M | 1 |
| Barillari, J | 1 |
| Bartsch, H | 3 |
| Gerhäuser, C | 3 |
| Strathmann, J | 1 |
| Löwinger, M | 1 |
| Nair, S | 1 |
| Hebbar, V | 1 |
| Shen, G | 1 |
| Gopalakrishnan, A | 1 |
| Khor, TO | 1 |
| Yu, S | 1 |
| Xu, C | 1 |
| Kong, AN | 1 |
| Gamet-Payrastre, L | 2 |
| Lumeau, S | 2 |
| Gasc, N | 2 |
| Cassar, G | 2 |
| Rollin, P | 1 |
| Tulliez, J | 2 |
| Li, P | 1 |
| Dupont, MA | 1 |
| Chevolleau, S | 1 |
| Tercé, F | 1 |
| Chung, FL | 1 |
| Conaway, CC | 1 |
| Rao, CV | 1 |
| Reddy, BS | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Human Intervention Trial Studying Gene Expression in High-Grade Prostatic Intraepithelial Neoplasia Following Consumption of Broccoli or Peas[NCT00535977] | 22 participants (Actual) | Interventional | 2005-04-30 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for sulforaphane and Cancer of Colon
| Article | Year |
|---|---|
Part of the series: from dietary antioxidants to regulators in cellular signaling and gene regulation. Sulforaphane and selenium, partners in adaptive response and prevention of cancer.
Topics: Animals; Antioxidants; Colonic Neoplasms; Gene Expression Regulation; Humans; Isothiocyanates; Mice; | 2006 |
42 other studies available for sulforaphane and Cancer of Colon
| Article | Year |
|---|---|
Enhanced in vitro biological activity of synthetic 2-(2-pyridyl) ethyl isothiocyanate compared to natural 4-(methylsulfinyl) butyl isothiocyanate.
Topics: Anticarcinogenic Agents; Apoptosis; Biomarkers, Tumor; Blotting, Western; Brassica; Cell Proliferati | 2012 |
EGF-functionalized lipid-polymer hybrid nanoparticles of 5-fluorouracil and sulforaphane with enhanced bioavailability and anticancer activity against colon carcinoma.
Topics: Biological Availability; Carcinoma; Cell Survival; Colonic Neoplasms; Drug Carriers; Drug Delivery S | 2022 |
Predicting sulforaphane-induced adverse effects in colon cancer patients via in silico investigation.
Topics: Adipocytes; Colonic Neoplasms; Gene Expression Regulation, Neoplastic; Gene Regulatory Networks; Hum | 2022 |
Sulforaphane has an additive anticancer effect to FOLFOX in highly metastatic human colon carcinoma cells.
Topics: Aldehyde Dehydrogenase 1 Family; Antineoplastic Combined Chemotherapy Protocols; Carcinoma; Colonic | 2022 |
Synergistic Combinations of Curcumin, Sulforaphane, and Dihydrocaffeic Acid against Human Colon Cancer Cells.
Topics: Caco-2 Cells; Caffeic Acids; Cell Line; Cell Proliferation; Cell Survival; Colonic Neoplasms; Curcum | 2020 |
Association between histone deacetylase activity and vitamin D-dependent gene expressions in relation to sulforaphane in human colorectal cancer cells.
Topics: Acetylation; Caco-2 Cells; Calcium Channels; Colonic Neoplasms; Gene Expression Regulation, Neoplast | 2021 |
Synergistic Interaction between 5-FU and an Analog of Sulforaphane-2-Oxohexyl Isothiocyanate-In an In Vitro Colon Cancer Model.
Topics: Antineoplastic Agents; Apoptosis; Autophagy; Cell Line, Tumor; Cell Proliferation; Colonic Neoplasms | 2021 |
Broccoli and human health: immunomodulatory effect of sulforaphane in a model of colon cancer.
Topics: Anti-Inflammatory Agents; Anticarcinogenic Agents; Brassica; Cell Line, Tumor; Cell Proliferation; C | 2018 |
Heterocyclic Analogs of Sulforaphane Trigger DNA Damage and Impede DNA Repair in Colon Cancer Cells: Interplay of HATs and HDACs.
Topics: Animals; Apoptosis; Brassica; Cell Cycle Checkpoints; Cell Line, Tumor; Colonic Neoplasms; DNA Damag | 2018 |
Sulforaphane, a Chemopreventive Compound, Inhibits Cyclooxygenase-2 and Microsomal Prostaglandin E Synthase-1 Expression in Human HT-29 Colon Cancer Cells.
Topics: Anticarcinogenic Agents; Cell Survival; Colonic Neoplasms; Cyclooxygenase 2; Cyclooxygenase 2 Inhibi | 2018 |
Lycopene, sulforaphane, quercetin, and curcumin applied together show improved antiproliferative potential in colon cancer cells in vitro.
Topics: Antineoplastic Agents; Cell Proliferation; Cell Survival; Colonic Neoplasms; Curcumin; Drug Synergis | 2019 |
HDAC turnover, CtIP acetylation and dysregulated DNA damage signaling in colon cancer cells treated with sulforaphane and related dietary isothiocyanates.
Topics: Acetylation; Antineoplastic Agents; Apoptosis; Autophagy; Carrier Proteins; Cell Cycle Checkpoints; | 2013 |
Glucosinolates from pak choi and broccoli induce enzymes and inhibit inflammation and colon cancer differently.
Topics: Animals; Anticarcinogenic Agents; Basic Helix-Loop-Helix Transcription Factors; Brassica; Colon; Col | 2014 |
Sulforaphane down-regulates SKP2 to stabilize p27(KIP1) for inducing antiproliferation in human colon adenocarcinoma cells.
Topics: Adenocarcinoma; Cell Line, Tumor; Cell Proliferation; Colonic Neoplasms; Cyclin-Dependent Kinase Inh | 2015 |
Synergy between sulforaphane and selenium in protection against oxidative damage in colonic CCD841 cells.
Topics: Anticarcinogenic Agents; Antioxidants; Apoptosis; Brassica; Cell Line; Cell Line, Tumor; Colon; Colo | 2015 |
Sulforaphane inhibits hypoxia-induced HIF-1α and VEGF expression and migration of human colon cancer cells.
Topics: Anticarcinogenic Agents; Blotting, Western; Cell Hypoxia; Cell Movement; Colonic Neoplasms; Enzyme-L | 2015 |
Sulforaphane Preconditioning Sensitizes Human Colon Cancer Cells towards the Bioreductive Anticancer Prodrug PR-104A.
Topics: 3-Hydroxysteroid Dehydrogenases; Aldo-Keto Reductase Family 1 Member C3; Antineoplastic Agents; Biol | 2016 |
Sulforaphane Induces Cell Death Through G2/M Phase Arrest and Triggers Apoptosis in HCT 116 Human Colon Cancer Cells.
Topics: Annexin A5; Antineoplastic Agents, Phytogenic; Apoptosis; Calcium; Caspases; Cell Cycle Proteins; Ce | 2016 |
A functional pseudogene, NMRAL2P, is regulated by Nrf2 and serves as a coactivator of NQO1 in sulforaphane-treated colon cancer cells.
Topics: Anticarcinogenic Agents; Cell Transformation, Neoplastic; Colon; Colonic Neoplasms; Gene Expression; | 2017 |
Mechanisms for the Inhibition of Colon Cancer Cells by Sulforaphane through Epigenetic Modulation of MicroRNA-21 and Human Telomerase Reverse Transcriptase (hTERT) Down-regulation.
Topics: Apoptosis; Cell Cycle; Cell Proliferation; Colonic Neoplasms; Epigenesis, Genetic; Gene Expression R | 2018 |
Serotonin receptors, novel targets of sulforaphane identified by proteomic analysis in Caco-2 cells.
Topics: Adenocarcinoma; Biomarkers, Pharmacological; Biomarkers, Tumor; Caco-2 Cells; Colonic Neoplasms; Dru | 2008 |
Activation of several concurrent proapoptic pathways by sulforaphane in human colon cancer cells SW620.
Topics: Anticarcinogenic Agents; Apoptosis; Caspase 2; Cell Line, Tumor; Cell Survival; Colonic Neoplasms; C | 2009 |
Inhibition of autophagy potentiates sulforaphane-induced apoptosis in human colon cancer cells.
Topics: Adenine; Anticarcinogenic Agents; Apoptosis; Autophagy; Blotting, Western; Caspases; Cell Line, Tumo | 2010 |
Comparison of the apoptosis-inducing capability of sulforaphane analogues in human colon cancer cells.
Topics: Anticarcinogenic Agents; Apoptosis; Caco-2 Cells; Cell Proliferation; Colonic Neoplasms; HCT116 Cell | 2010 |
Prolonged sulforaphane treatment activates survival signaling in nontumorigenic NCM460 colon cells but apoptotic signaling in tumorigenic HCT116 colon cells.
Topics: Anticarcinogenic Agents; Apoptosis; Cell Cycle; Cell Line; Cell Proliferation; Colon; Colonic Neopla | 2011 |
Sulforaphane induces cytotoxicity and lysosome- and mitochondria-dependent cell death in colon cancer cells with deleted p53.
Topics: Anticarcinogenic Agents; bcl-2-Associated X Protein; Cell Proliferation; Cell Survival; Colonic Neop | 2011 |
Histone deacetylase turnover and recovery in sulforaphane-treated colon cancer cells: competing actions of 14-3-3 and Pin1 in HDAC3/SMRT corepressor complex dissociation/reassembly.
Topics: 14-3-3 Proteins; Acetylation; Anticarcinogenic Agents; Apoptosis; Caspase 3; Cell Cycle; Cell Line, | 2011 |
Myrosinase hydrolysates of Brassica oleraceae L. var. italica reduce the risk of colon cancer.
Topics: Antineoplastic Agents; Brassica; Cell Line, Tumor; Cell Survival; Chromatography, Liquid; Colonic Ne | 2012 |
Glutathione peroxidase-2 and selenium decreased inflammation and tumors in a mouse model of inflammation-associated carcinogenesis whereas sulforaphane effects differed with selenium supply.
Topics: Animals; Apoptosis; Azoxymethane; Cell Transformation, Neoplastic; Colitis; Colon; Colonic Neoplasms | 2012 |
Effects of phytochemicals sulforaphane on uridine diphosphate-glucuronosyltransferase expression as well as cell-cycle arrest and apoptosis in human colon cancer Caco-2 cells.
Topics: Apoptosis; bcl-2-Associated X Protein; Caco-2 Cells; Cell Cycle Checkpoints; Cell Nucleus; Colonic N | 2012 |
Sulforaphane inhibits growth of a colon cancer cell line.
Topics: Anticarcinogenic Agents; Cell Division; Colonic Neoplasms; Dose-Response Relationship, Drug; HT29 Ce | 2004 |
Interactions between sulforaphane and apigenin in the induction of UGT1A1 and GSTA1 in CaCo-2 cells.
Topics: Adenocarcinoma; Anticarcinogenic Agents; Apigenin; Bacterial Proteins; Caco-2 Cells; Carrier Protein | 2004 |
[Induction of uridine 5'-diphosphate-glucuronosyltransferase gene expression by sulforaphane and its mechanism: experimental study in human colon cancel cells].
Topics: Anticarcinogenic Agents; Caco-2 Cells; Colonic Neoplasms; Glucuronosyltransferase; Humans; Imidazole | 2005 |
Transcriptome analysis of human colon Caco-2 cells exposed to sulforaphane.
Topics: Anticarcinogenic Agents; Cell Differentiation; Cell Line, Tumor; Colonic Neoplasms; Enzymes; Gene Ex | 2005 |
Comparison of growth inhibition profiles and mechanisms of apoptosis induction in human colon cancer cell lines by isothiocyanates and indoles from Brassicaceae.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Brassicaceae; Caspase 7; Caspase 9; Caspases; Cell Lin | 2006 |
Quantitative combination effects between sulforaphane and 3,3'-diindolylmethane on proliferation of human colon cancer cells in vitro.
Topics: Anticarcinogenic Agents; Apoptosis; Brassica; Cell Line, Tumor; Cell Proliferation; Colonic Neoplasm | 2007 |
Biphasic modulation of cell proliferation by sulforaphane at physiologically relevant exposure times in a human colon cancer cell line.
Topics: Anticarcinogenic Agents; Apoptosis; Cell Cycle; Cell Division; Cell Line, Tumor; Colonic Neoplasms; | 2007 |
Synergistic effects of a combination of dietary factors sulforaphane and (-) epigallocatechin-3-gallate in HT-29 AP-1 human colon carcinoma cells.
Topics: Catechin; Cell Survival; Cellular Senescence; Colonic Neoplasms; Drug Synergism; HT29 Cells; Humans; | 2008 |
In vitro antiproliferative effects of sulforaphane on human colon cancer cell line SW620.
Topics: Anticarcinogenic Agents; Apoptosis; Cell Line, Tumor; Cell Proliferation; Colonic Neoplasms; DNA Dam | 2007 |
Selective cytostatic and cytotoxic effects of glucosinolates hydrolysis products on human colon cancer cells in vitro.
Topics: Antineoplastic Agents; Caco-2 Cells; Cell Cycle; Cell Division; Colonic Neoplasms; Dose-Response Rel | 1998 |
Sulforaphane, a naturally occurring isothiocyanate, induces cell cycle arrest and apoptosis in HT29 human colon cancer cells.
Topics: Animals; Anticarcinogenic Agents; Apoptosis; Colonic Neoplasms; HT29 Cells; Humans; Isothiocyanates; | 2000 |
Chemoprevention of colonic aberrant crypt foci in Fischer rats by sulforaphane and phenethyl isothiocyanate.
Topics: Animals; Anticarcinogenic Agents; Azoxymethane; Body Weight; Brassica; Carcinogens; Colon; Colonic N | 2000 |