sulforaphane has been researched along with Brain Neoplasms in 6 studies
sulforaphane: from Cardaria draba L.
sulforaphane : An isothiocyanate having a 4-(methylsulfinyl)butyl group attached to the nitrogen.
Brain Neoplasms: Neoplasms of the intracranial components of the central nervous system, including the cerebral hemispheres, basal ganglia, hypothalamus, thalamus, brain stem, and cerebellum. Brain neoplasms are subdivided into primary (originating from brain tissue) and secondary (i.e., metastatic) forms. Primary neoplasms are subdivided into benign and malignant forms. In general, brain tumors may also be classified by age of onset, histologic type, or presenting location in the brain.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We previously demonstrated that sulforaphane (SFN) inhibited invasion via sustained activation of ERK1/2 in human glioblastoma cells." | 7.85 | Sulforaphane-cysteine induces apoptosis by sustained activation of ERK1/2 and caspase 3 in human glioblastoma U373MG and U87MG cells. ( Geng, Y; Hu, Y; Lin, K; Tian, H; Wu, S; Wu, W; Yang, G; Zhou, Y, 2017) |
| "The survival benefits of patients with glioblastoma (GBM) remain unsatisfactory due to the intrinsic or acquired resistance to temozolomide (TMZ)." | 7.83 | Sulforaphane reverses chemo-resistance to temozolomide in glioblastoma cells by NF-κB-dependent pathway downregulating MGMT expression. ( Han, J; Lan, F; Wu, Q; Yang, Y; Yu, H; Yue, X, 2016) |
| "We previously demonstrated that sulforaphane (SFN) inhibited invasion via sustained activation of ERK1/2 in human glioblastoma cells." | 3.85 | Sulforaphane-cysteine induces apoptosis by sustained activation of ERK1/2 and caspase 3 in human glioblastoma U373MG and U87MG cells. ( Geng, Y; Hu, Y; Lin, K; Tian, H; Wu, S; Wu, W; Yang, G; Zhou, Y, 2017) |
| "The survival benefits of patients with glioblastoma (GBM) remain unsatisfactory due to the intrinsic or acquired resistance to temozolomide (TMZ)." | 3.83 | Sulforaphane reverses chemo-resistance to temozolomide in glioblastoma cells by NF-κB-dependent pathway downregulating MGMT expression. ( Han, J; Lan, F; Wu, Q; Yang, Y; Yu, H; Yue, X, 2016) |
| "Glioblastoma is the most common primary tumor of the brain and has few long-term survivors." | 1.46 | Modulating glioma-mediated myeloid-derived suppressor cell development with sulforaphane. ( Daniels, DJ; de Mooij, T; Johnson, AJ; Kaptzan, T; Kumar, R; Parney, IF; Peterson, TE, 2017) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (16.67) | 29.6817 |
| 2010's | 4 (66.67) | 24.3611 |
| 2020's | 1 (16.67) | 2.80 |
| Authors | Studies |
|---|---|
| Sita, G | 1 |
| Graziosi, A | 1 |
| Hrelia, P | 1 |
| Morroni, F | 1 |
| Wu, S | 1 |
| Zhou, Y | 1 |
| Yang, G | 1 |
| Tian, H | 1 |
| Geng, Y | 1 |
| Hu, Y | 1 |
| Lin, K | 1 |
| Wu, W | 1 |
| Kumar, R | 1 |
| de Mooij, T | 1 |
| Peterson, TE | 1 |
| Kaptzan, T | 1 |
| Johnson, AJ | 1 |
| Daniels, DJ | 1 |
| Parney, IF | 1 |
| Lan, F | 1 |
| Yang, Y | 1 |
| Han, J | 1 |
| Wu, Q | 1 |
| Yu, H | 1 |
| Yue, X | 1 |
| Miao, Z | 1 |
| Yu, F | 1 |
| Ren, Y | 1 |
| Yang, J | 1 |
| Annabi, B | 1 |
| Rojas-Sutterlin, S | 1 |
| Laroche, M | 1 |
| Lachambre, MP | 1 |
| Moumdjian, R | 1 |
| Béliveau, R | 1 |
6 other studies available for sulforaphane and Brain Neoplasms
| Article | Year |
|---|---|
Sulforaphane Causes Cell Cycle Arrest and Apoptosis in Human Glioblastoma U87MG and U373MG Cell Lines under Hypoxic Conditions.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Brain Neoplasms; Cell Cycle Checkpoints; Cell Line, Tu | 2021 |
Sulforaphane-cysteine induces apoptosis by sustained activation of ERK1/2 and caspase 3 in human glioblastoma U373MG and U87MG cells.
Topics: Apoptosis; Brain Neoplasms; Caspase 3; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cysteine | 2017 |
Modulating glioma-mediated myeloid-derived suppressor cell development with sulforaphane.
Topics: Brain Neoplasms; CD11b Antigen; Cell Hypoxia; Cell Line, Tumor; Culture Media, Conditioned; Fucosylt | 2017 |
Sulforaphane reverses chemo-resistance to temozolomide in glioblastoma cells by NF-κB-dependent pathway downregulating MGMT expression.
Topics: Animals; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Dacarbazine; DNA Modifica | 2016 |
d,l-Sulforaphane Induces ROS-Dependent Apoptosis in Human Gliomablastoma Cells by Inactivating STAT3 Signaling Pathway.
Topics: Antineoplastic Agents; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Glioblastoma; Humans; Isothiocy | 2017 |
The diet-derived sulforaphane inhibits matrix metalloproteinase-9-activated human brain microvascular endothelial cell migration and tubulogenesis.
Topics: Anticarcinogenic Agents; Blood-Brain Barrier; Brain; Brain Neoplasms; Brassica; Capillaries; Cell Li | 2008 |