Page last updated: 2024-11-04

sulforaphane and Brain Neoplasms

sulforaphane has been researched along with Brain Neoplasms in 6 studies

sulforaphane: from Cardaria draba L.
sulforaphane : An isothiocyanate having a 4-(methylsulfinyl)butyl group attached to the nitrogen.

Brain Neoplasms: Neoplasms of the intracranial components of the central nervous system, including the cerebral hemispheres, basal ganglia, hypothalamus, thalamus, brain stem, and cerebellum. Brain neoplasms are subdivided into primary (originating from brain tissue) and secondary (i.e., metastatic) forms. Primary neoplasms are subdivided into benign and malignant forms. In general, brain tumors may also be classified by age of onset, histologic type, or presenting location in the brain.

Research Excerpts

ExcerptRelevanceReference
"We previously demonstrated that sulforaphane (SFN) inhibited invasion via sustained activation of ERK1/2 in human glioblastoma cells."7.85Sulforaphane-cysteine induces apoptosis by sustained activation of ERK1/2 and caspase 3 in human glioblastoma U373MG and U87MG cells. ( Geng, Y; Hu, Y; Lin, K; Tian, H; Wu, S; Wu, W; Yang, G; Zhou, Y, 2017)
"The survival benefits of patients with glioblastoma (GBM) remain unsatisfactory due to the intrinsic or acquired resistance to temozolomide (TMZ)."7.83Sulforaphane reverses chemo-resistance to temozolomide in glioblastoma cells by NF-κB-dependent pathway downregulating MGMT expression. ( Han, J; Lan, F; Wu, Q; Yang, Y; Yu, H; Yue, X, 2016)
"We previously demonstrated that sulforaphane (SFN) inhibited invasion via sustained activation of ERK1/2 in human glioblastoma cells."3.85Sulforaphane-cysteine induces apoptosis by sustained activation of ERK1/2 and caspase 3 in human glioblastoma U373MG and U87MG cells. ( Geng, Y; Hu, Y; Lin, K; Tian, H; Wu, S; Wu, W; Yang, G; Zhou, Y, 2017)
"The survival benefits of patients with glioblastoma (GBM) remain unsatisfactory due to the intrinsic or acquired resistance to temozolomide (TMZ)."3.83Sulforaphane reverses chemo-resistance to temozolomide in glioblastoma cells by NF-κB-dependent pathway downregulating MGMT expression. ( Han, J; Lan, F; Wu, Q; Yang, Y; Yu, H; Yue, X, 2016)
"Glioblastoma is the most common primary tumor of the brain and has few long-term survivors."1.46Modulating glioma-mediated myeloid-derived suppressor cell development with sulforaphane. ( Daniels, DJ; de Mooij, T; Johnson, AJ; Kaptzan, T; Kumar, R; Parney, IF; Peterson, TE, 2017)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (16.67)29.6817
2010's4 (66.67)24.3611
2020's1 (16.67)2.80

Authors

AuthorsStudies
Sita, G1
Graziosi, A1
Hrelia, P1
Morroni, F1
Wu, S1
Zhou, Y1
Yang, G1
Tian, H1
Geng, Y1
Hu, Y1
Lin, K1
Wu, W1
Kumar, R1
de Mooij, T1
Peterson, TE1
Kaptzan, T1
Johnson, AJ1
Daniels, DJ1
Parney, IF1
Lan, F1
Yang, Y1
Han, J1
Wu, Q1
Yu, H1
Yue, X1
Miao, Z1
Yu, F1
Ren, Y1
Yang, J1
Annabi, B1
Rojas-Sutterlin, S1
Laroche, M1
Lachambre, MP1
Moumdjian, R1
Béliveau, R1

Other Studies

6 other studies available for sulforaphane and Brain Neoplasms

ArticleYear
Sulforaphane Causes Cell Cycle Arrest and Apoptosis in Human Glioblastoma U87MG and U373MG Cell Lines under Hypoxic Conditions.
    International journal of molecular sciences, 2021, Oct-18, Volume: 22, Issue:20

    Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Brain Neoplasms; Cell Cycle Checkpoints; Cell Line, Tu

2021
Sulforaphane-cysteine induces apoptosis by sustained activation of ERK1/2 and caspase 3 in human glioblastoma U373MG and U87MG cells.
    Oncology reports, 2017, Volume: 37, Issue:5

    Topics: Apoptosis; Brain Neoplasms; Caspase 3; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cysteine

2017
Modulating glioma-mediated myeloid-derived suppressor cell development with sulforaphane.
    PloS one, 2017, Volume: 12, Issue:6

    Topics: Brain Neoplasms; CD11b Antigen; Cell Hypoxia; Cell Line, Tumor; Culture Media, Conditioned; Fucosylt

2017
Sulforaphane reverses chemo-resistance to temozolomide in glioblastoma cells by NF-κB-dependent pathway downregulating MGMT expression.
    International journal of oncology, 2016, Volume: 48, Issue:2

    Topics: Animals; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Dacarbazine; DNA Modifica

2016
d,l-Sulforaphane Induces ROS-Dependent Apoptosis in Human Gliomablastoma Cells by Inactivating STAT3 Signaling Pathway.
    International journal of molecular sciences, 2017, Jan-04, Volume: 18, Issue:1

    Topics: Antineoplastic Agents; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Glioblastoma; Humans; Isothiocy

2017
The diet-derived sulforaphane inhibits matrix metalloproteinase-9-activated human brain microvascular endothelial cell migration and tubulogenesis.
    Molecular nutrition & food research, 2008, Volume: 52, Issue:6

    Topics: Anticarcinogenic Agents; Blood-Brain Barrier; Brain; Brain Neoplasms; Brassica; Capillaries; Cell Li

2008