sulforaphane has been researched along with Body Weight in 20 studies
sulforaphane: from Cardaria draba L.
sulforaphane : An isothiocyanate having a 4-(methylsulfinyl)butyl group attached to the nitrogen.
Body Weight: The mass or quantity of heaviness of an individual. It is expressed by units of pounds or kilograms.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The purpose of this work was to compare the influences of sulforaphane (SFN) to those of the standard insulin sensitizer pioglitazone (PIO) on high fructose diet (HFrD)-induced insulin resistance, dyslipidemia, hepatosteatosis, and vascular dysfunction in rats." | 7.91 | Comparison of the effects of sulforaphane and pioglitazone on insulin resistance and associated dyslipidemia, hepatosteatosis, and endothelial dysfunction in fructose-fed rats. ( Gameil, NM; Shawky, NM; Shehatou, GSG; Suddek, GM, 2019) |
| "The anticancer effects of sulforaphane (SFN), which is found in cruciferous vegetables, were studied on KPL-1 human breast cancer cells in vitro and in vivo." | 7.77 | Sulforaphane inhibits the growth of KPL-1 human breast cancer cells in vitro and suppresses the growth and metastasis of orthotopically transplanted KPL-1 cells in female athymic mice. ( Kanematsu, S; Kimura, A; Kuro, M; Lai, YC; Miki, H; Sasaki, T; Tsubura, A; Uehara, N; Yoshizawa, K; Yuri, T, 2011) |
| "We have shown previously that naturally occurring isothiocyanates derived from cruciferous vegetables and their N-acetylcysteine conjugates inhibit lung adenoma formation induced by tobacco carcinogens in A/J mice at the post-initiation stage." | 7.73 | Phenethyl isothiocyanate and sulforaphane and their N-acetylcysteine conjugates inhibit malignant progression of lung adenomas induced by tobacco carcinogens in A/J mice. ( Chung, FL; Conaway, CC; Hecht, SS; McIntee, EJ; Pittman, B; Schwartz, JE; Tian, D; Wang, CX; Yang, YM, 2005) |
| "Treatment with sulforaphane restored animals' body weight, reduced blood glucose, glycated hemoglobin, and increased insulin levels." | 5.48 | Extracellular Matrix Remodeling and Modulation of Inflammation and Oxidative Stress by Sulforaphane in Experimental Diabetic Peripheral Neuropathy. ( Abdelkader, NF; El Awdan, SA; El-Shabrawy, OA; Moustafa, PE; Zaki, HF, 2018) |
| "Treatment with sulforaphane promotes microglia differentiation from pro-inflammatory M1 to anti-inflammatory M2 phenotype and reduces activation of astrocytes in hyperammonemic rats." | 5.43 | Hyperammonemia induces glial activation, neuroinflammation and alters neurotransmitter receptors in hippocampus, impairing spatial learning: reversal by sulforaphane. ( Agustí, A; Cabrera-Pastor, A; Felipo, V; Hernández-Rabaza, V; Llansola, M; Malaguarnera, M; Taoro-González, L, 2016) |
| "Obesity is associated with metabolic disorders." | 5.40 | Sulforaphane attenuates obesity by inhibiting adipogenesis and activating the AMPK pathway in obese mice. ( Choi, KM; Hong, JT; Kim, SJ; Kim, W; Lee, MK; Lee, YM; Lee, YS; Shin, KO; Yoo, HS; Yu, JY; Yun, YP, 2014) |
| "The purpose of this work was to compare the influences of sulforaphane (SFN) to those of the standard insulin sensitizer pioglitazone (PIO) on high fructose diet (HFrD)-induced insulin resistance, dyslipidemia, hepatosteatosis, and vascular dysfunction in rats." | 3.91 | Comparison of the effects of sulforaphane and pioglitazone on insulin resistance and associated dyslipidemia, hepatosteatosis, and endothelial dysfunction in fructose-fed rats. ( Gameil, NM; Shawky, NM; Shehatou, GSG; Suddek, GM, 2019) |
| "Diet-induced obesity (DIO) is commonly associated with hyperleptinemia and leptin resistance." | 3.88 | Sulforaphane improves leptin responsiveness in high-fat high-sucrose diet-fed obese mice. ( Segar, L; Shawky, NM, 2018) |
| "The anticancer effects of sulforaphane (SFN), which is found in cruciferous vegetables, were studied on KPL-1 human breast cancer cells in vitro and in vivo." | 3.77 | Sulforaphane inhibits the growth of KPL-1 human breast cancer cells in vitro and suppresses the growth and metastasis of orthotopically transplanted KPL-1 cells in female athymic mice. ( Kanematsu, S; Kimura, A; Kuro, M; Lai, YC; Miki, H; Sasaki, T; Tsubura, A; Uehara, N; Yoshizawa, K; Yuri, T, 2011) |
| "We have shown previously that naturally occurring isothiocyanates derived from cruciferous vegetables and their N-acetylcysteine conjugates inhibit lung adenoma formation induced by tobacco carcinogens in A/J mice at the post-initiation stage." | 3.73 | Phenethyl isothiocyanate and sulforaphane and their N-acetylcysteine conjugates inhibit malignant progression of lung adenomas induced by tobacco carcinogens in A/J mice. ( Chung, FL; Conaway, CC; Hecht, SS; McIntee, EJ; Pittman, B; Schwartz, JE; Tian, D; Wang, CX; Yang, YM, 2005) |
| "Treatment with sulforaphane restored animals' body weight, reduced blood glucose, glycated hemoglobin, and increased insulin levels." | 1.48 | Extracellular Matrix Remodeling and Modulation of Inflammation and Oxidative Stress by Sulforaphane in Experimental Diabetic Peripheral Neuropathy. ( Abdelkader, NF; El Awdan, SA; El-Shabrawy, OA; Moustafa, PE; Zaki, HF, 2018) |
| "Treatment with sulforaphane promotes microglia differentiation from pro-inflammatory M1 to anti-inflammatory M2 phenotype and reduces activation of astrocytes in hyperammonemic rats." | 1.43 | Hyperammonemia induces glial activation, neuroinflammation and alters neurotransmitter receptors in hippocampus, impairing spatial learning: reversal by sulforaphane. ( Agustí, A; Cabrera-Pastor, A; Felipo, V; Hernández-Rabaza, V; Llansola, M; Malaguarnera, M; Taoro-González, L, 2016) |
| " Hence, objective of the current study was to investigate the potential toxic effects of ACS c-SLN combined chemopreventive regimens following acute (3 days), subacute (28 days), and subchronic (90 days) administrations by oral gavage in BALB/c mice." | 1.43 | Preclinical systemic toxicity evaluation of chitosan-solid lipid nanoparticle-encapsulated aspirin and curcumin in combination with free sulforaphane in BALB/c mice. ( Chenreddy, S; Khamas, W; Prabhu, S; Thakkar, A; Thio, A; Wang, J, 2016) |
| "Sulforaphane (SFN) is a natural and highly effective antioxidant." | 1.43 | Sulforaphane Prevents Testicular Damage in Kunming Mice Exposed to Cadmium via Activation of Nrf2/ARE Signaling Pathways. ( Gao, F; Guo, Y; He, JB; Li, L; Li, P; Liu, MD; Long, M; Yang, SH; Yu, LH; Zhang, Y, 2016) |
| "Obesity is associated with metabolic disorders." | 1.40 | Sulforaphane attenuates obesity by inhibiting adipogenesis and activating the AMPK pathway in obese mice. ( Choi, KM; Hong, JT; Kim, SJ; Kim, W; Lee, MK; Lee, YM; Lee, YS; Shin, KO; Yoo, HS; Yu, JY; Yun, YP, 2014) |
| "Sulforaphane (SFN) is a natural, biologically active compound extracted from cruciferous vegetables such as broccoli and cabbage with anti-inflammatory and anti-cancer properties." | 1.37 | Chemopreventive role of sulforaphane by upholding the GSH redox cycle in pre- and post-initiation phases of experimental lung carcinogenesis. ( Gayathri, R; Gunassekaran, G; Murugan, S; Priya, DK; Sakthisekaran, D, 2011) |
| " SFN and PEITC and their NAC conjugates were administered by gavage either three times weekly for 8 weeks (5 and 20 micromol, respectively) after AOM dosing (post-initiation stage) or once daily for 3 days (20 and 50 micromol, respectively) before AOM treatment (initiation stage)." | 1.31 | Chemoprevention of colonic aberrant crypt foci in Fischer rats by sulforaphane and phenethyl isothiocyanate. ( Chung, FL; Conaway, CC; Rao, CV; Reddy, BS, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (15.00) | 29.6817 |
| 2010's | 16 (80.00) | 24.3611 |
| 2020's | 1 (5.00) | 2.80 |
| Authors | Studies |
|---|---|
| Jiang, Y | 1 |
| Li, HY | 1 |
| Li, XH | 1 |
| Lu, J | 1 |
| Zhang, Q | 1 |
| Bai, CG | 1 |
| Chen, Y | 1 |
| Isaacson, RH | 1 |
| Beier, JI | 1 |
| Khoo, NK | 1 |
| Freeman, BA | 1 |
| Freyberg, Z | 1 |
| Arteel, GE | 1 |
| McDonnell, C | 1 |
| Leánez, S | 1 |
| Pol, O | 1 |
| Sun, B | 1 |
| Zhang, X | 1 |
| Yin, Y | 1 |
| Sun, H | 1 |
| Ge, H | 1 |
| Li, W | 1 |
| Wan, X | 1 |
| Liu, C | 1 |
| Chen, YB | 1 |
| Gu, M | 1 |
| Cai, ZK | 1 |
| Chen, Q | 1 |
| Wang, Z | 1 |
| Moustafa, PE | 1 |
| Abdelkader, NF | 1 |
| El Awdan, SA | 1 |
| El-Shabrawy, OA | 1 |
| Zaki, HF | 1 |
| Shawky, NM | 2 |
| Segar, L | 1 |
| Shehatou, GSG | 1 |
| Suddek, GM | 1 |
| Gameil, NM | 1 |
| Jahan, S | 1 |
| Khan, M | 1 |
| Ahmed, S | 1 |
| Ullah, H | 1 |
| Choi, KM | 1 |
| Lee, YS | 1 |
| Kim, W | 1 |
| Kim, SJ | 1 |
| Shin, KO | 1 |
| Yu, JY | 1 |
| Lee, MK | 1 |
| Lee, YM | 1 |
| Hong, JT | 1 |
| Yun, YP | 1 |
| Yoo, HS | 1 |
| Zhang, R | 1 |
| Zhang, J | 1 |
| Fang, L | 1 |
| Li, X | 1 |
| Zhao, Y | 1 |
| Shi, W | 1 |
| An, L | 1 |
| Hernández-Rabaza, V | 1 |
| Cabrera-Pastor, A | 1 |
| Taoro-González, L | 1 |
| Malaguarnera, M | 1 |
| Agustí, A | 1 |
| Llansola, M | 1 |
| Felipo, V | 1 |
| Thakkar, A | 1 |
| Chenreddy, S | 1 |
| Thio, A | 1 |
| Khamas, W | 1 |
| Wang, J | 1 |
| Prabhu, S | 1 |
| Yang, SH | 1 |
| Long, M | 1 |
| Yu, LH | 1 |
| Li, L | 1 |
| Li, P | 1 |
| Zhang, Y | 1 |
| Guo, Y | 1 |
| Gao, F | 1 |
| Liu, MD | 1 |
| He, JB | 1 |
| Priya, DK | 1 |
| Gayathri, R | 1 |
| Gunassekaran, G | 1 |
| Murugan, S | 1 |
| Sakthisekaran, D | 1 |
| Kanematsu, S | 1 |
| Yoshizawa, K | 1 |
| Uehara, N | 1 |
| Miki, H | 1 |
| Sasaki, T | 1 |
| Kuro, M | 1 |
| Lai, YC | 1 |
| Kimura, A | 1 |
| Yuri, T | 1 |
| Tsubura, A | 1 |
| Negi, G | 1 |
| Kumar, A | 1 |
| Sharma, SS | 1 |
| Conaway, CC | 2 |
| Wang, CX | 1 |
| Pittman, B | 1 |
| Yang, YM | 1 |
| Schwartz, JE | 1 |
| Tian, D | 1 |
| McIntee, EJ | 1 |
| Hecht, SS | 1 |
| Chung, FL | 2 |
| Shen, G | 1 |
| Khor, TO | 1 |
| Hu, R | 1 |
| Yu, S | 1 |
| Nair, S | 1 |
| Ho, CT | 1 |
| Reddy, BS | 2 |
| Huang, MT | 1 |
| Newmark, HL | 1 |
| Kong, AN | 1 |
| Rao, CV | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Randomized,Double-blind, Placebo-controlled, Efficacy and Safety Study of Sulforaphane in Patients With Prodromal to Mild Alzheimer's Disease[NCT04213391] | 160 participants (Anticipated) | Interventional | 2020-05-10 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
20 other studies available for sulforaphane and Body Weight
| Article | Year |
|---|---|
Therapeutic effects of isothiocyanate prodrugs on rheumatoid arthritis.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Body Weight; Half-Life; Iso | 2018 |
Olanzapine-induced liver injury in mice: aggravation by high-fat diet and protection with sulforaphane.
Topics: Animals; Antioxidants; Antipsychotic Agents; Body Weight; Chemical and Drug Induced Liver Injury; Di | 2020 |
The induction of the transcription factor Nrf2 enhances the antinociceptive effects of delta-opioid receptors in diabetic mice.
Topics: Animals; Benzamides; Blood Glucose; Blotting, Western; Body Weight; Diabetes Mellitus, Experimental; | 2017 |
Effects of sulforaphane and vitamin E on cognitive disorder and oxidative damage in lead-exposed mice hippocampus at lactation.
Topics: Animals; Behavior, Animal; Body Weight; Cognition Disorders; Female; Hippocampus; Isothiocyanates; L | 2017 |
Sulforaphane Treatment of Stress Urinary Incontinence Via the Nrf2-ARE Pathway in a Rat Model.
Topics: Animals; Anticarcinogenic Agents; bcl-2-Associated X Protein; Body Weight; Catalase; Female; Glutath | 2017 |
Extracellular Matrix Remodeling and Modulation of Inflammation and Oxidative Stress by Sulforaphane in Experimental Diabetic Peripheral Neuropathy.
Topics: Animals; Anticarcinogenic Agents; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental; Diabe | 2018 |
Sulforaphane improves leptin responsiveness in high-fat high-sucrose diet-fed obese mice.
Topics: Animals; Body Weight; Diet, High-Fat; Eating; Isothiocyanates; Leptin; Male; Mice; Mice, Inbred C57B | 2018 |
Comparison of the effects of sulforaphane and pioglitazone on insulin resistance and associated dyslipidemia, hepatosteatosis, and endothelial dysfunction in fructose-fed rats.
Topics: Animals; Aorta, Thoracic; Blood Glucose; Body Weight; C-Reactive Protein; Dyslipidemias; Fatty Liver | 2019 |
Comparative analysis of antioxidants against cadmium induced reproductive toxicity in adult male rats.
Topics: Animals; Antioxidants; Body Weight; Cadmium; Case-Control Studies; Isothiocyanates; Male; Plant Extr | 2014 |
Sulforaphane attenuates obesity by inhibiting adipogenesis and activating the AMPK pathway in obese mice.
Topics: Adenylate Kinase; Adipogenesis; Animals; Body Weight; Cholesterol; Enzyme Activation; Isothiocyanate | 2014 |
Neuroprotective effects of sulforaphane on cholinergic neurons in mice with Alzheimer's disease-like lesions.
Topics: Aluminum; Alzheimer Disease; Animals; Body Weight; CA1 Region, Hippocampal; Cholinergic Neurons; Fem | 2014 |
Hyperammonemia induces glial activation, neuroinflammation and alters neurotransmitter receptors in hippocampus, impairing spatial learning: reversal by sulforaphane.
Topics: Animals; Anti-Inflammatory Agents; Body Weight; Cytokines; Disease Models, Animal; Encephalitis; Gen | 2016 |
Preclinical systemic toxicity evaluation of chitosan-solid lipid nanoparticle-encapsulated aspirin and curcumin in combination with free sulforaphane in BALB/c mice.
Topics: Administration, Oral; Animals; Aspirin; Body Weight; Chitosan; Curcumin; Drug Liberation; Female; Is | 2016 |
Sulforaphane Prevents Testicular Damage in Kunming Mice Exposed to Cadmium via Activation of Nrf2/ARE Signaling Pathways.
Topics: Animals; Anticarcinogenic Agents; Antioxidant Response Elements; Body Weight; Cadmium; Disease Model | 2016 |
Chemopreventive role of sulforaphane by upholding the GSH redox cycle in pre- and post-initiation phases of experimental lung carcinogenesis.
Topics: Adenosine Triphosphatases; Animals; Anticarcinogenic Agents; Antioxidants; Benzo(a)pyrene; Body Weig | 2011 |
Sulforaphane inhibits the growth of KPL-1 human breast cancer cells in vitro and suppresses the growth and metastasis of orthotopically transplanted KPL-1 cells in female athymic mice.
Topics: Animals; Antineoplastic Agents; Apoptosis; Body Weight; Breast Neoplasms; Cell Line, Tumor; Cell Pro | 2011 |
Nrf2 and NF-κB modulation by sulforaphane counteracts multiple manifestations of diabetic neuropathy in rats and high glucose-induced changes.
Topics: Animals; Blood Glucose; Body Weight; Cell Line, Transformed; Diabetic Neuropathies; Disease Models, | 2011 |
Phenethyl isothiocyanate and sulforaphane and their N-acetylcysteine conjugates inhibit malignant progression of lung adenomas induced by tobacco carcinogens in A/J mice.
Topics: Acetylcysteine; Adenocarcinoma; Adenoma; Animals; Anticarcinogenic Agents; Benzo(a)pyrene; Body Weig | 2005 |
Chemoprevention of familial adenomatous polyposis by natural dietary compounds sulforaphane and dibenzoylmethane alone and in combination in ApcMin/+ mouse.
Topics: Adenomatous Polyposis Coli; Animals; Anticarcinogenic Agents; Antineoplastic Combined Chemotherapy P | 2007 |
Chemoprevention of colonic aberrant crypt foci in Fischer rats by sulforaphane and phenethyl isothiocyanate.
Topics: Animals; Anticarcinogenic Agents; Azoxymethane; Body Weight; Brassica; Carcinogens; Colon; Colonic N | 2000 |