sulforaphane has been researched along with Autism in 4 studies
sulforaphane: from Cardaria draba L.
sulforaphane : An isothiocyanate having a 4-(methylsulfinyl)butyl group attached to the nitrogen.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Children with autism spectrum disorder (ASD) have urinary metabolites suggesting impairments in several pathways, including oxidative stress, inflammation, mitochondrial dysfunction, and gut microbiome alterations." | 6.87 | Identification of urinary metabolites that correlate with clinical improvements in children with autism treated with sulforaphane from broccoli. ( Bent, S; Cornblatt, B; Dang, K; Delucchi, K; Fahey, JW; Hendren, RL; Kinchen, JM; Lawton, B; Warren, T; Widjaja, F, 2018) |
| "These mechanisms lead to improvement in autism-like symptoms in BTBR mice." | 5.51 | Nrf2 activator, sulforaphane ameliorates autism-like symptoms through suppression of Th17 related signaling and rectification of oxidant-antioxidant imbalance in periphery and brain of BTBR T+tf/J mice. ( Ahmad, SF; Al-Harbi, NO; Alqahtani, F; Alqinyah, M; Attia, SM; Bakheet, SA; Ibrahim, KE; Nadeem, A, 2019) |
| "Children with autism spectrum disorder (ASD) have urinary metabolites suggesting impairments in several pathways, including oxidative stress, inflammation, mitochondrial dysfunction, and gut microbiome alterations." | 2.87 | Identification of urinary metabolites that correlate with clinical improvements in children with autism treated with sulforaphane from broccoli. ( Bent, S; Cornblatt, B; Dang, K; Delucchi, K; Fahey, JW; Hendren, RL; Kinchen, JM; Lawton, B; Warren, T; Widjaja, F, 2018) |
| "Sulforaphane is an isothiocyanate occurring in stored form as glucoraphanin in cruciferous vegetables such as cabbage, cauliflower, and kale, and at high levels in broccoli especially in broccoli sprouts." | 2.61 | Isothiocyanate from Broccoli, Sulforaphane, and Its Properties. ( Anzenbacher, P; Anzenbacherova, E; Vanduchova, A, 2019) |
| "These mechanisms lead to improvement in autism-like symptoms in BTBR mice." | 1.51 | Nrf2 activator, sulforaphane ameliorates autism-like symptoms through suppression of Th17 related signaling and rectification of oxidant-antioxidant imbalance in periphery and brain of BTBR T+tf/J mice. ( Ahmad, SF; Al-Harbi, NO; Alqahtani, F; Alqinyah, M; Attia, SM; Bakheet, SA; Ibrahim, KE; Nadeem, A, 2019) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (75.00) | 24.3611 |
| 2020's | 1 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| Magner, M | 1 |
| Thorová, K | 1 |
| Župová, V | 1 |
| Houška, M | 1 |
| Švandová, I | 1 |
| Novotná, P | 1 |
| Tříska, J | 1 |
| Vrchotová, N | 1 |
| Soural, I | 1 |
| Jílek, L | 1 |
| Bent, S | 1 |
| Lawton, B | 1 |
| Warren, T | 1 |
| Widjaja, F | 1 |
| Dang, K | 1 |
| Fahey, JW | 1 |
| Cornblatt, B | 1 |
| Kinchen, JM | 1 |
| Delucchi, K | 1 |
| Hendren, RL | 1 |
| Vanduchova, A | 1 |
| Anzenbacher, P | 1 |
| Anzenbacherova, E | 1 |
| Nadeem, A | 1 |
| Ahmad, SF | 1 |
| Al-Harbi, NO | 1 |
| Attia, SM | 1 |
| Bakheet, SA | 1 |
| Ibrahim, KE | 1 |
| Alqahtani, F | 1 |
| Alqinyah, M | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Decreasing Risk of Psychosis by Sulforaphane: Study Protocol for a Randomized, Double-blind, Placebo-controlled, Clinical Multicenter Trial (DROPS Trial)[NCT03932136] | Phase 3 | 300 participants (Anticipated) | Interventional | 2019-07-14 | Recruiting | ||
| An Examination of Changes in Urinary Metabolites With Use of an Antioxidant Supplement, Sulforaphane, in School-aged Children With Autism[NCT02654743] | Phase 3 | 21 participants (Actual) | Interventional | 2016-01-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for sulforaphane and Autism
| Article | Year |
|---|---|
Isothiocyanate from Broccoli, Sulforaphane, and Its Properties.
Topics: Animals; Antineoplastic Agents, Phytogenic; Autistic Disorder; Brassica; Glucosinolates; Humans; Imi | 2019 |
2 trials available for sulforaphane and Autism
| Article | Year |
|---|---|
Sulforaphane Treatment in Children with Autism: A Prospective Randomized Double-Blind Study.
Topics: Autism Spectrum Disorder; Autistic Disorder; Child; Double-Blind Method; Humans; Isothiocyanates; Pr | 2023 |
Identification of urinary metabolites that correlate with clinical improvements in children with autism treated with sulforaphane from broccoli.
Topics: Adolescent; Antioxidants; Autistic Disorder; Biomarkers; Brassica; Child; Female; Humans; Isothiocya | 2018 |
Identification of urinary metabolites that correlate with clinical improvements in children with autism treated with sulforaphane from broccoli.
Topics: Adolescent; Antioxidants; Autistic Disorder; Biomarkers; Brassica; Child; Female; Humans; Isothiocya | 2018 |
Identification of urinary metabolites that correlate with clinical improvements in children with autism treated with sulforaphane from broccoli.
Topics: Adolescent; Antioxidants; Autistic Disorder; Biomarkers; Brassica; Child; Female; Humans; Isothiocya | 2018 |
Identification of urinary metabolites that correlate with clinical improvements in children with autism treated with sulforaphane from broccoli.
Topics: Adolescent; Antioxidants; Autistic Disorder; Biomarkers; Brassica; Child; Female; Humans; Isothiocya | 2018 |
1 other study available for sulforaphane and Autism
| Article | Year |
|---|---|
Nrf2 activator, sulforaphane ameliorates autism-like symptoms through suppression of Th17 related signaling and rectification of oxidant-antioxidant imbalance in periphery and brain of BTBR T+tf/J mice.
Topics: Animals; Antioxidants; Autism Spectrum Disorder; Autistic Disorder; Behavior, Animal; Brain; Cytokin | 2019 |